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Displaying drugs 801 - 825 of 1131 in total
A bone morphogenetic protein that is widely expressed during EMBRYONIC DEVELOPMENT. It is both a potent osteogenic factor and a specific regulator of nephrogenesis. Eptotermin alfa is an ingredient in the EMA-withdrawn product Osigraft.
Approved
Investigational
Withdrawn
Matched Synonyms: … Osteogenic protein 1 ... Bone morphogenetic protein 7 ... Human recombinant bone morphogenetic protein 7 …
Matched Description: … It is both a potent osteogenic factor and a specific regulator of nephrogenesis. ... A bone morphogenetic protein that is widely expressed during EMBRYONIC DEVELOPMENT. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins ... Drugs Affecting Bone Structure and Mineralization ... Proteins ... Bone Morphogenetic Proteins
Efbemalenograstim alfa is a long-acting recombinant fusion protein of granulocyte-colony stimulating factor (G-CSF) due to the addition of the Fc portion of human IgG2, allowing for once-per-cycle administration.[L48852,A262167] As endogenous G-CSF mediates the differentiation of hematopoietic stem cells into granulocytes and eventually neutrophils, the administration of recombinant G-CSF like efbemalenograstim...
Approved
Matched Synonyms: … Rh g-csf fc fusion protein f-627 ... Recombinant dimeric g-csf fusion protein f627 …
Matched Description: … thus reducing the severity and duration of neutropenia. ... GC-627-05 in the US and Europe respectively. ... A262167] As endogenous G-CSF mediates the differentiation of hematopoietic stem cells into granulocytes and
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Polistes metricus venom protein is an extract of Polistes metricus venom. Polistes metricus venom protein is used in allergenic testing.
Approved
Matched Synonyms: … Metricus paper wasp venom protein
Matched Name: … Polistes metricus venom protein
Matched Description: … Polistes metricus venom protein is used in allergenic testing. ... Polistes metricus venom protein is an extract of Polistes metricus venom. …
Matched Categories: … Bee and Wasp Venom …
Experimental
Matched Synonyms: … Silver protein
Matched Categories: … Amino Acids, Peptides, and Proteins ... Proteins
Osteoarthritis (OA) is a progressive and degenerative joint disease marked by loss of cartilage, bone changes, and synovial membrane inflammation. Treatment with chondroprotective drugs, such as glucosamine sulfate may offer additional benefits to nonsteroidal anti-inflammatory drugs treating the painful symptoms of OA. Glucosamine is commonly used over the counter as...
Approved
Investigational
Matched Description: … changes, and synovial membrane inflammation. ... Osteoarthritis (OA) is a progressive and degenerative joint disease marked by loss of cartilage, bone ... for arthritic joint pain, although its acceptance as a medical therapy varies due to contradictory and
Matched Mixtures name: … Bee Venom Joint And Bone Therapy Drops ... Blackmores Joint Formula with Glucosamine and Chondroitin ... Live-well® OsteSAMIN Plus CHONDROITIN Capsule …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Products: … Live-well™ OSTESAMIN 500 Capsule ... Live-well OsteSAMIN 1500 Powder …
Efmoroctocog alfa is a fully recombinant factor VIII-Fc fusion protein (rFVIIIFc) with an extended half-life compared with conventional factor VIII (FVIII) preparations, including recombinant FVIII (rFVIII) products such as DB13999 . It is an antihemorrhagic agent used in replacement therapy for patients with haemophilia A (congenital factor VIII deficiency). It...
Approved
Investigational
Matched Synonyms: … Antihemophilic factor (recombinant, FC fusion protein) ... Antihemophilic Factor (Recombinant BDD), FC Fusion Protein ... Coagulation factor VIII recombinant immunoglubulin g1 fusion protein
Matched Description: … Efmoroctocog alfa is a first commercially available rFVIII-Fc fusion protein (rFVIIIFc) where the conjugated ... is purified endogenous Factor VIII from human pooled blood and contains both A- and B-subunits. ... polyethylene glycol is covalently fused to the dimeric Fc domain of human immunoglobulin G1, a long-lived
EF-022 is a modified version of vitamin D binding protein macrophage activator, with potential antineoplastic and anti-angiogenic activities.
Investigational
Matched Synonyms: … Modified vitamin D binding protein ... Modified Vitamin D Binding Protein Macrophage Activator …
Matched Description: … and anti-angiogenic activities. ... EF-022 is a modified version of vitamin D binding protein macrophage activator, with potential antineoplastic …
Bevifimod is under investigation in clinical trial NCT01749787 (Safety Study of PRTX-100 With Methotrexate or Leflunomide to Treat Active Rheumatoid Arthritis).
Investigational
Matched Synonyms: … STAPHYLOCOCCAL PROTEIN A …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Proteins ... Bacterial Proteins
Cry5B is a pore-forming crystal protein produced by and derived from the soil bacterium Bacillus thuringiensis. With demonstrated anthelmintic properties, it has been investigated in the treatment of parasitic intestinal infections.[A259372, A259377]
Investigational
Matched Synonyms: … Bacillus thuringiensis Cry5B Protein
Matched Description: … Cry5B is a pore-forming crystal protein produced by and derived from the soil bacterium _Bacillus thuringiensis ... With demonstrated anthelmintic properties, it has been investigated in the treatment of parasitic intestinal …
Tibolone is a synthetic steroid hormone drug, which is mainly non-selective in its binding profile, acting as an agonist primarily at estrogen receptors (ER), with a preference for ER alpha . Tibolone (Livial, Org OD 14), produced by Organon (West Orange, NJ), is a synthetic steroid that possesses estrogenic, androgenic...
Approved
Investigational
Matched Description: … and the treatment of post-menopausal symptoms [L1720]. ... produced by Organon (West Orange, NJ), is a synthetic steroid that possesses estrogenic, androgenic and ... Tibolone is approved in 90 countries to manage menopausal symptoms and in 45 countries to prevent the …
Matched Categories: … Genito Urinary System and Sex Hormones ... Estrogens, Antiestrogens, and Estrogen Agonist-Antagonists ... Hormones, Hormone Substitutes, and Hormone Antagonists ... Sex Hormones and Modulators of the Genital System …
Matched Products: … Liviel - Tabletten …
Investigational
Matched Synonyms: … BACTERICIDAL PERMEABILITY-INCREASING PROTEIN OPEBACAN [MI] ... 1-193-BACTERICIDAL/PERMEABILITY-INCREASING PROTEIN (132-ALANINE) (HUMAN) ... 1-193-BACTERICIDAL/PERMEABILITY-INCREASING PROTEIN (132-ALANINE) (HUMAN REDUCED) …
Human papillomavirus type 11 L1 capsid protein antigen is contained in Gardasil, or a recombinant Human Papillomavirus Quadrivalent (Types 6, 11, 16, and 18) vaccine for intramuscular injection. It is an immunization for young men and women 9-26 years of age for the prevention of diseases caused by Human Papillomavirus...
Approved
Matched Synonyms: … L1 protein, Human papillomavirus type 11 Vaccine ... Recombinant human papillomavirus type 11 L1 protein
Matched Name: … Human papillomavirus type 11 L1 capsid protein antigen …
Matched Description: … by Human Papillomavirus (HPV) types 6, 11, 16 and 18. ... cerevisiae* and self-assembled into VLPs. ... Papillomavirus Quadrivalent (Types 6, 11, 16, and 18) vaccine for intramuscular injection. …
Human papillomavirus type 58 L1 capsid protein antigen is contained in Gardasil is a vaccine for intramuscular injection. It is an immunization for young men and women 9-26 years of age for the prevention of diseases caused by Human Papillomavirus (HPV) type 58. The vaccine is prepared from the purified...
Approved
Matched Synonyms: … L1 protein, Human papillomavirus type 58 Vaccine ... Recombinant human papillomavirus type 58 L1 protein
Matched Name: … Human papillomavirus type 58 L1 capsid protein antigen …
Matched Description: … It is an immunization for young men and women 9-26 years of age for the prevention of diseases caused ... HPV Type 58 which are produced by separate fermentations in recombinant *Saccharomyces cerevisiae* and ... Human papillomavirus type 58 L1 capsid protein antigen is contained in Gardasil is a vaccine for intramuscular …
Marstacimab is a human Monoclonal Antibody Directed Against Tissue Factor Pathway Inhibitor currently being developed by Pfizer for the treatment of hemophilia A and hemophilia B.
Investigational
Matched Synonyms: … Immunoglobulin g1-lambda, anti-(human tissue factor pathway inhibitor (tfpi, extrinsic pathway inhibitor ... inhibitor) (human monoclonal pf-06741086 .gamma.1-chain), disulfide with human monoclonal pf-06741086 .lambda
Matched Description: … Tissue Factor Pathway Inhibitor currently being developed by Pfizer for the treatment of hemophilia A and
Matched Categories: … Amino Acids, Peptides, and Proteins ... Proteins ... Blood Proteins
Macadamia seed oil glycereth-8 esters is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Name: … Macadamia seed oil glycereth-8 esters …
Matched Description: … Macadamia seed oil glycereth-8 esters is a plant/plant extract used in some OTC (over-the-counter) products …
Polistes annularis venom protein is an extract of Polistes annularis venom. Polistes annularis venom protein is used in allergenic testing.
Approved
Matched Synonyms: … red paper wasp venom protein
Matched Name: … Polistes annularis venom protein
Matched Description: … Polistes annularis venom protein is used in allergenic testing. ... Polistes annularis venom protein is an extract of Polistes annularis venom. …
Matched Categories: … Bee and Wasp Venom …
Vespula pensylvanica venom protein is an extract of Vespula pensylvanica venom. Vespula pensylvanica venom protein is used in allergenic testing.
Approved
Matched Synonyms: … western yellow jacket venom protein
Matched Name: … Vespula pensylvanica venom protein
Matched Description: … Vespula pensylvanica venom protein is used in allergenic testing. ... Vespula pensylvanica venom protein is an extract of Vespula pensylvanica venom. …
Matched Categories: … Bee and Wasp Venom …
Maplirpacept is a recombinant fusion protein consisting of the CD47-binding domain of human signal regulatory protein alpha (SIRPa) linked to the IgG4 Fc region of human IgG.
Investigational
Matched Synonyms: … 1-118-Signal regulatory protein α (human) fusion protein with immunoglobulin G4 [128-proline] (human ... SIRPA-IGG4-FC FUSION PROTEIN TTI-622 …
Matched Description: … protein alpha (SIRPa) linked to the IgG4 Fc region of human IgG. ... Maplirpacept is a recombinant fusion protein consisting of the CD47-binding domain of human signal regulatory …
Eftrenonacog alfa is a long-acting recombinant fusion protein used in the treatment of hemophilia B. It is comprised of a single molecule of human factor IX (FIX) covalently linked to the constant region (Fc) domain of human IgG1 via recombinant DNA technology in a human embryonic kidney cell line (HEK293H)...
Approved
Investigational
Matched Synonyms: … Recombinant human coagulation factor IX, FC Fusion protein ... Coagulation factor IX recombinant immunoglubulin g1 fusion protein
Matched Description: … benefits of prolonged therapeutic efficacy, less frequent intravenous injections for patient convenience and ... blood disorder with an incidence of approximately once every 30,000 male births in all populations and ... It was first approved by the FDA in March 2014 and later approved by the EMA in May 2016. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes ... Proteins ... Blood Proteins ... Protein Precursors …
Sole constituent of "Vogelbeerol" oil obtained by steam distillation of the acidified juice of the ripe berries of the mountain ash.
Experimental
Matched Synonyms: … Sorbic oil
Matched Description: … Sole constituent of "Vogelbeerol" oil obtained by steam distillation of the acidified juice of the ripe …
Approved
Matched Synonyms: … Recombinant haemagglutinin protein-strain A (H3N2) …
AMT-101 is a recombinant human interleukin-10 fusion protein.
Investigational
Matched Synonyms: … Recombinant human interleukin-10 fusion protein
Matched Description: … AMT-101 is a recombinant human interleukin-10 fusion protein. …
Ramipril is a prodrug belonging to the angiotensin-converting enzyme (ACE) inhibitor class of medications. It is metabolized to ramiprilat in the liver and, to a lesser extent, kidneys. Ramiprilat is a potent, competitive inhibitor of ACE, the enzyme responsible for the conversion of angiotensin I (ATI) to angiotensin II (ATII)....
Approved
Matched Description: … It is metabolized to ramiprilat in the liver and, to a lesser extent, kidneys. ... ATII regulates blood pressure and is a key component of the renin-angiotensin-aldosterone system (RAAS ... Ramipril may be used in the treatment of hypertension, congestive heart failure, nephropathy, and to …
Matched Categories: … Protease Inhibitors ... ACE Inhibitors and Calcium Channel Blockers ... ACE Inhibitors and Diuretics ... ramipril and felodipine ... ramipril and amlodipine …
Matched Products: … DELIX PROTECT 10MG TABL ... DELIX PROTECT 10 MG TABLET, 90 ADET ... DELIX PROTECT 10 MG TABLET, 28 ADET …
Efavaleukin alfa is a fusion protein consisting of interleukin mutein fused to the C-terminus of an immunoglobulin G Fc domain by way of a G4S linker. It is under investigation in clinical trial NCT03422627 (Safety and Efficacy of AMG 592 in Subjects With Steroid Refractory Chronic Graft Versus Host Disease).
Investigational
Matched Synonyms: … Fc il-2 mutein fusion protein (amg-592) ... protein with interleukin 2 (synthetic human mutein), dimer ... Immunoglobulin g1 (fc domain-containing fragment) fusion protein with peptide (synthetic linker) fusion …
Matched Description: … It is under investigation in clinical trial NCT03422627 (Safety and Efficacy of AMG 592 in Subjects With ... Efavaleukin alfa is a fusion protein consisting of interleukin mutein fused to the C-terminus of an immunoglobulin …
Approved
Matched Synonyms: … Diphtheria CRM197 protein ... Corynebacterium diphtheriae CRM-197 protein
Matched Name: … Corynebacterium diphtheriae CRM197 protein
Matched Categories: … Amino Acids, Peptides, and Proteins ... Proteins
Displaying drugs 801 - 825 of 1131 in total