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Displaying drugs 8251 - 8275 of 11493 in total

4-(2,4-Dimethyl-Thiazol-5-Yl)-Pyrimidin-2-Ylamine

Experimental
Matched Name: … 4-(2,4-Dimethyl-Thiazol-5-Yl)-Pyrimidin-2-Ylamine …
Matched Iupac: … 4-(2,4-dimethyl-1,3-thiazol-5-yl)pyrimidin-2-amine …

4-[(5-bromopyridin-2-yl)amino]-4-oxobutanoic acid

Experimental
Matched Name: … 4-[(5-bromopyridin-2-yl)amino]-4-oxobutanoic acid …
Matched Iupac: … 3-[(5-bromopyridin-2-yl)carbamoyl]propanoic acid …

Lidorestat

Investigational
Matched Iupac: … 2-{3-[(4,5,7-trifluoro-1,3-benzothiazol-2-yl)methyl]-1H-indol-1-yl}acetic acid …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

(R,R)-2,3-Butanediol

Experimental

Biphenyl-2,3-Diol

Experimental

N-[4-(4-nitrophenylphospho)butanoyl]-D-alanine

Experimental
Matched Synonyms: … N-[4-(4-nitrophenylphospho)butyryl]-D-alanine …
Matched Name: … N-[4-(4-nitrophenylphospho)butanoyl]-D-alanine …
Matched Iupac: … (2R)-2-{4-[hydroxy(4-nitrophenoxy)phosphoryl]butanamido}propanoic acid …

Fenretinide

A synthetic retinoid that is used orally as a chemopreventive against prostate cancer and in women at risk of developing contralateral breast cancer. It is also effective as an antineoplastic agent.
Investigational
Matched Synonyms: … 4-HPR ... 4-hydroxy(phenyl)retinamide ... 4-hydroxyphenyl retinamide …
Matched Iupac: … (2E,4E,6E,8E)-N-(4-hydroxyphenyl)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenamide …

JZP-386 free base

JZP-386 is a deuterium-containing analog of sodium oxybate. Its safety, pharmacokinetics and pharmacodynamics were evaluated in clinical trial NCT02215499.
Investigational

Golvatinib

Golvatinib has been investigated for the treatment of Platinum-Resistant Squamous Cell Carcinoma of the Head and Neck.
Investigational
Matched Iupac: … N'1-{2-fluoro-4-[(2-{[4-(4-methylpiperazin-1-yl)piperidine-1-carbonyl]amino}pyridin-4-yl)oxy]phenyl}- ... N1-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Acazicolcept

Investigational
Matched Synonyms: … 1-122-INDUCIBLE COSTIMULATORY LIGAND PROTEIN (52-HISTIDINE,57-TYROSINE,100-ARGININE) (HUMAN) FUSION PROTEIN ... WITH SYNTHETIC PEPTIDE LINKER (GGGGSGGGGS) FUSION PROTEIN WITH IMMUNOGLOBULIN G1 (HUMAN .GAMMA.1-CHAIN ... HUMAN INDUCIBLE T-CELL CO-STIMULATOR LIGAND (ICOS LIGAND) N-TERMINAL FRAGMENT (1-122) (VARIANT (N52>H …

Coumermycin A1

Experimental
Matched Iupac: … (3S,4R,5S,6S)-5-hydroxy-6-[(4-hydroxy-3-{5-[(4-hydroxy-7-{[(2S,3S,4R,5S)-3-hydroxy-5-methoxy-6,6-dimethyl ... -4-(5-methyl-1H-pyrrole-2-carbonyloxy)oxan-2-yl]oxy}-8-methyl-2-oxo-2H-chromen-3-yl)carbamoyl]-4-methyl ... -1H-pyrrole-3-amido}-8-methyl-2-oxo-2H-chromen-7-yl)oxy]-3-methoxy-2,2-dimethyloxan-4-yl 5-methyl-1H-pyrrole …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Imidazole-4-carboxylic acid

Imidazole-4-carboxylic acid is under investigation in clinical trial NCT00583895 (Safety and Efficacy Study of Imcooh Cream in Patients Suffering From Moderate Atopic Dermatitis).
Investigational
Matched Synonyms: … 4-Carboxyimidazole ... 4-Imidazolecarboxylic acid …
Matched Name: … Imidazole-4-carboxylic acid …
Matched Iupac: … 1H-imidazole-4-carboxylic acid …
Matched Description: … Imidazole-4-carboxylic acid is under investigation in clinical trial NCT00583895 (Safety and Efficacy …

Pacmilimab

Pacmilimab is under investigation in clinical trial NCT04596150 (Study to Evaluate the Safety and Antitumor Activity of CX-2009 Monotherapy and in Combination With CX-072 in Advanced Breast Cancer).
Investigational
Matched Synonyms: … IMMUNOGLOBULIN G4, ANTI-(HUMAN PROGRAMMED CELL DEATH-LIGAND 1) (HUMAN MONOCLONAL CX-072 .GAMMA.4-CHAIN …

Begelomab

Begelomab is a murine monoclonal antibody against CD26.
Experimental
Investigational
Matched Synonyms: … IMMUNOGLOBULIN G2B-KAPPA, ANTI-(HOMO SAPIENS DPP4(DIPEPTIDYLPEPTIDASE 4, DIPEPTIDYLPEPTIDASE IV, ADENOSINE …

Recombinant CD40-ligand

Recombinant CD40-ligand is under investigation in clinical trial NCT00053391 (Vaccine Therapy in Treating Patients With Stage III or Stage IV Melanoma).
Investigational

NV1020

NV1020, a genetically engineered herpes simplex virus, is a novel anticancer therapeutic.
Investigational

AGRO100

AGRO100 is an oligonucleotide that functions as an aptamer and binds to nucleolin, a protein found intranuclear in all cells, but uniquely expressed on the surface of tumor cells. Such binding leads to internalization of the complex, and a strong anti-proliferative response in the tumor cell. Pre-clinical testing demonstrates that...
Investigational

AS1409

AS1409 is a genetically engineered fusion protein made up of two distinct components. One is the cytokine IL12, which has anti-cancer activity. The other is an antibody that targets tumours. It is developed by Antisoma is in a phase I of clinical trial for the treatment of renal cancer and...
Investigational

LX1031

LX1031 is an orally-dosed drug candidate for irritable bowel syndrome and other gastrointestinal disorders. LX1031 was generated by Lexicon medicinal chemists, and its target was internally identified as a key control point for the regulation of peripheral serotonin levels. LX1031 is designed to act locally in the gastrointestinal tract by...
Investigational

AP1081

A transdermal gel containing ethinyl estradiol and norelgestromin being investigated by Antares Pharma for use as a female contraceptive.
Investigational

SR-123781A

SR-123781A is a synthetic hexadecasaccharide Factor IIa and Xa antagonist. It is under investigation by Sanofi-Aventis and Organon for the treatment of thrombosis and acute coronary syndromes (ACS).
Investigational

Epicept NP-1

EpiCept NP-1 is a prescription topical analgesic cream designed to provide effective, long-term relief from the pain of peripheral neuropathies. Peripheral neuropathies are medical conditions caused by damage to the nerves in the peripheral nervous system. The peripheral nervous system includes nerves that run from the brain and spinal cord...
Investigational
Matched Name: … Epicept NP-1 …
Matched Iupac: … N1-(4-methyl-2-nitrophenyl)propane-1,3-diamine …
Matched Description: … EpiCept NP-1 is a prescription topical analgesic cream designed to provide effective, long-term relief ... EpiCept NP-1 Cream is a patented formulation containing two FDA-approved drugs, amitriptyline (a widely-used …

ISIS 113715

ISIS 113715 is our second-generation antisense inhibitor of protein tyrosine phosphatase 1b, or PTP‑1b, for the treatment of type 2 diabetes. In early trials, ISIS 113715 induced statistically significant improvements in multiple measures of glucose control along with statistically significant reductions in LDL-cholesterol.
Investigational

NLX-P101

NLX-P101, gene therapy is developed by Neurologix to treat Parkinson’s disease. The gene is glutamic acid decarboxylase (GAD), whose product synthesizes the major inhibitory neurotransmitter in the brain, (gamma)-aminobutyric acid (GABA), and targets the subthalamic nucleus (STN), which is overactive in patients with Parkinson’s disease. NLX-P101 is being evaluated as...
Investigational

TG1024

Investigational
Displaying drugs 8251 - 8275 of 11493 in total