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Displaying drugs 8276 - 8300 of 11091 in total
3,6,9,12,15,18-HEXAOXAICOSANE
Experimental
Arbaclofen Placarbil
Arbaclofen Placerbil is a prodrug of Arbaclofen, which is a selective gamma-amino-butyric acid type B receptor agonist and the R-enantiomer of baclofen. It was discovered, and has been patented by XenoPort as a new chemical entity with an improved pharmacokinetic profile compared to baclofen, which allows for sustained release properties....
Investigational
Matched Iupac: … (3R)-3-(4-chlorophenyl)-4-({[(1S)-2-methyl-1-[(2-methylpropanoyl)oxy]propoxy]carbonyl}amino)butanoic …
Fitusiran
Fitusiran is under investigation in clinical trial NCT02554773 (An Open-label Extension Study of an Investigational Drug, ALN-AT3SC, in Patients With Moderate or Severe Hemophilia A or B).
Investigational
2,6-Diamino-(S)-9-[2-(Phosphonomethoxy)Propyl]Purine
Experimental
Matched Name: … 2,6-Diamino-(S)-9-[2-(Phosphonomethoxy)Propyl]Purine …
Matched Iupac: … ({[(2S)-1-(2,6-diamino-9H-purin-9-yl)propan-2-yl]oxy}methyl)phosphonate …
Matched Iupac: … ({[(2S)-1-(2,6-diamino-9H-purin-9-yl)propan-2-yl]oxy}methyl)phosphonate …
Amlitelimab
Amlitelimab is under investigation in clinical trial NCT06181435 (A Study to Evaluate the Efficacy and Safety of Subcutaneous Amlitelimab Monotherapy Compared With Placebo in Participants Aged 12 Years and Older With Moderate-to-severe Atopic Dermatitis (COAST 2)).
Investigational
Matched Description: … With Placebo in Participants Aged 12 Years and Older With Moderate-to-severe Atopic Dermatitis (COAST 2) …
TERT-BUTYL 2-CYANO-2-METHYLHYDRAZINECARBOXYLATE
Experimental
Matched Name: … TERT-BUTYL 2-CYANO-2-METHYLHYDRAZINECARBOXYLATE …
2-Ethylhexyl 4-phenylbenzophenone-2'-carboxylate
Experimental
Matched Name: … 2-Ethylhexyl 4-phenylbenzophenone-2'-carboxylate …
Matched Iupac: … 2-ethylhexyl 2-{[1,1'-biphenyl]-4-carbonyl}benzoate …
Matched Iupac: … 2-ethylhexyl 2-{[1,1'-biphenyl]-4-carbonyl}benzoate …
4-hydroxycoumarin
Experimental
Matched Synonyms: … 4-hydroxy-2-chromenone ... 4-hydroxychromen-2-one ... 4-hydroxy-2H-1-benzopyran-2-one …
Matched Iupac: … 4-hydroxy-2H-chromen-2-one …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Iupac: … 4-hydroxy-2H-chromen-2-one …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Afamitresgene autoleucel
Afamitresgene autoleucel is a specific Peptide Enhanced Affinity Receptor T cell product comprised of autologous CD4 and CD8 positive T cells genetically engineered with an affinity-enhanced T cell receptor to target cancer-testis antigen MAGE-A4
Investigational
Succinyl-Coenzyme A
Experimental
Matched Iupac: … 4-[(2-{3-[(2R)-3-[({[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)oxolan-2-yl ... ]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)methyl]-2-hydroxy-3-methylbutanamido]propanamido …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Malonyl-CoA
A coenzyme A derivative which plays a key role in the fatty acid synthesis in the cytoplasmic and microsomal systems.
Experimental
Matched Iupac: … 3-[(2-{3-[(2R)-3-[({[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)oxolan-2-yl ... ]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)methyl]-2-hydroxy-3-methylbutanamido]propanamido ... }ethyl)sulfanyl]-3-oxopropanoic acid …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Seletracetam
Seletracetam is a pyrrolidone derivative and with a structural similarity to newer generation antiepileptic drug levetiracetam. It binds to the same target as levetiracetam but with higher affinity and has shown potent seizure suppression in models of acquired and genetic epilepsy with high CNS tolerability. It is predicted to have...
Investigational
Matched Synonyms: … (2S)-2-((4S)-4-(2,2-Difluoroethenyl)-2-oxopyrrolidin-1-yl)butanamide …
Matched Iupac: … (2S)-2-[(4S)-4-(2,2-difluoroethenyl)-2-oxopyrrolidin-1-yl]butanamide …
Matched Iupac: … (2S)-2-[(4S)-4-(2,2-difluoroethenyl)-2-oxopyrrolidin-1-yl]butanamide …
1,2-Dichloro-Propane
Experimental
2-Hydroxyquinoline
Experimental
Matched Synonyms: … 2-quinolone ... Quinolin-2-ol ... 2(1H)-Quinolinone …
Matched Name: … 2-Hydroxyquinoline …
Matched Iupac: … 1,2-dihydroquinolin-2-one …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Name: … 2-Hydroxyquinoline …
Matched Iupac: … 1,2-dihydroquinolin-2-one …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Human interleukin-2
Human interleukin-2 is under investigation in clinical trial NCT03475134 (TIL-ACT After NMA Chemo With IL-2 and Nivo Rescue in mMEL).
Investigational
Matched Synonyms: … IL-2 ... INTERLEUKIN-2 ... Liposome encapsulated recombinant interleukin-2 …
Matched Name: … Human interleukin-2 …
Matched Description: … IL-2 and Nivo Rescue in mMEL). ... Human interleukin-2 is under investigation in clinical trial NCT03475134 (TIL-ACT After NMA Chemo With …
Matched Categories: … Interleukin-2 …
Matched Name: … Human interleukin-2 …
Matched Description: … IL-2 and Nivo Rescue in mMEL). ... Human interleukin-2 is under investigation in clinical trial NCT03475134 (TIL-ACT After NMA Chemo With …
Matched Categories: … Interleukin-2 …
GSK2798745
GSK2798745 is under investigation in clinical trial NCT03372603 (A Study to Assess the Effectiveness and Side Effects of GSK2798745 in Participants With Chronic Cough).
Investigational
Matched Iupac: … 1-{[(5S,7S)-3-[5-(2-hydroxypropan-2-yl)pyrazin-2-yl]-7-methyl-2-oxo-1-oxa-3-azaspiro[4.5]decan-7-yl]methyl …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
GSK2245035
GSK2245035 is under investigation in clinical trial NCT02833974 (Effect of the GSK2245035 on the Allergen-induced Asthmatic Response).
Investigational
Matched Iupac: … 6-amino-2-[(2S)-pentan-2-yloxy]-9-[5-(piperidin-1-yl)pentyl]-8,9-dihydro-7H-purin-8-one …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Glial growth factor 2
Glial growth factor 2 has been used in trials studying the treatment of Heart Failure.
Investigational
Matched Name: … Glial growth factor 2 …
Matched Description: … Glial growth factor 2 has been used in trials studying the treatment of Heart Failure. …
Matched Description: … Glial growth factor 2 has been used in trials studying the treatment of Heart Failure. …
Tesaglitazar
Tesaglitazar is a dual peroxisome proliferator-activated receptor alpha/gamma agonist which improves apolipoprotein levels in non-diabetic subjects with insulin resistance. Tesaglitazar is a proposed treatment for type 2 diabetes and has completed several phase III clinical trials, however in May 2006 AstraZeneca announced that they had discontinued further development.
Investigational
Matched Iupac: … (2S)-2-ethoxy-3-(4-{2-[4-(methanesulfonyloxy)phenyl]ethoxy}phenyl)propanoic acid …
Matched Description: … Tesaglitazar is a proposed treatment for type 2 diabetes and has completed several phase III clinical …
Matched Description: … Tesaglitazar is a proposed treatment for type 2 diabetes and has completed several phase III clinical …
CHIR-124
CHIR-124 is a potent inhibitor of Chk1 that potentiates the cytotoxicity of topoisomerase I poisons in vitro and in vivo.
Experimental
Matched Iupac: … 4-{[(3S)-1-azabicyclo[2.2.2]octan-3-yl]amino}-3-(1H-1,3-benzodiazol-2-yl)-6-chloro-1,2-dihydroquinolin ... -2-one …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
L-Baclofen
L-Baclofen has been used in trials studying the treatment of Trigeminal Neuralgia.
Investigational
Matched Iupac: … (3S)-4-amino-3-(4-chlorophenyl)butanoic acid …
Delta-2-Albomycin A1
Experimental
Matched Name: … Delta-2-Albomycin A1 …
Matched Iupac: … (8S,11R,14R)-14-amino-8-{[(1S)-1-{[(1R,2R)-2-[(2R,3S,4S,5R)-5-[(4Z)-4-(carbamoylimino)-3-methyl-2-oxo ... -1,2,3,4-tetrahydropyrimidin-1-yl]-3,4-dihydroxythiolan-2-yl]-1-carboxy-2-hydroxyethyl]carbamoyl}-2-hydroxyethyl …
Matched Iupac: … (8S,11R,14R)-14-amino-8-{[(1S)-1-{[(1R,2R)-2-[(2R,3S,4S,5R)-5-[(4Z)-4-(carbamoylimino)-3-methyl-2-oxo ... -1,2,3,4-tetrahydropyrimidin-1-yl]-3,4-dihydroxythiolan-2-yl]-1-carboxy-2-hydroxyethyl]carbamoyl}-2-hydroxyethyl …
L-2-aminopimelic acid
Experimental
Matched Synonyms: … 2-Aminopimelic acid ... (2S)-2-Aminoheptanedioic acid ... (S)-2-aminoheptanedioic acid …
Matched Name: … L-2-aminopimelic acid …
Matched Iupac: … (2S)-2-aminoheptanedioic acid …
Matched Name: … L-2-aminopimelic acid …
Matched Iupac: … (2S)-2-aminoheptanedioic acid …
Displaying drugs 8276 - 8300 of 11091 in total