Displaying drugs 8376 - 8400 of 11304 in total
AT2220
AT2220 is an experimental, oral therapy for the treatment of Pompe disease and belongs to a class of molecules known as pharmacological chaperones. It is a small molecule designed to act as a pharmacological chaperone that specifically binds, stabilizes, and facilitates the proper folding and trafficking of α-glucosidase (GAA). GAA...
Investigational
GSK-2018682
GSK2018682 has been investigated for the treatment of Multiple Sclerosis, Relapsing-Remitting.
Investigational
Matched Iupac: … 4-(4-{5-[5-chloro-6-(propan-2-yloxy)pyridin-3-yl]-1,2,4-oxadiazol-3-yl}-1H-indol-1-yl)butanoic acid …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
GSK-2881078
Investigational
Matched Iupac: … 1-[(2R)-1-methanesulfonylpropan-2-yl]-4-(trifluoromethyl)-1H-indole-5-carbonitrile …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
DT2216
Investigational
Matched Iupac: … (2S,4R)-1-[(2S)-2-(7-{4-[(3R)-3-{[4-({[4-(4-{[2-(4-chlorophenyl)-5,5-dimethylcyclohex-1-en-1-yl]methyl ... }piperazin-1-yl)phenyl]formamido}sulfonyl)-2-trifluoromethanesulfonylphenyl]amino}-4-(phenylsulfanyl) ... -5-yl)phenyl]ethyl]pyrrolidine-2-carboxamide ... butyl]piperazin-1-yl}-7-oxoheptanamido)-3,3-dimethylbutanoyl]-4-hydroxy-N-[(1S)-1-[4-(4-methyl-1,3-thiazol …
3-Methylthiofentanyl
3-Methyl-thiofentanyl is a fentanyl analog and an opioid analgesic that works by inducing central nervous system (CNS) depression.
Experimental
Illicit
Matched Synonyms: … 3-Methyl-thiofentanyl …
Matched Name: … 3-Methylthiofentanyl …
Matched Iupac: … N-{3-methyl-1-[2-(thiophen-2-yl)ethyl]piperidin-4-yl}-N-phenylpropanamide …
Matched Description: … 3-Methyl-thiofentanyl is a [fentanyl] analog and an opioid analgesic that works by inducing central nervous …
Matched Name: … 3-Methylthiofentanyl …
Matched Iupac: … N-{3-methyl-1-[2-(thiophen-2-yl)ethyl]piperidin-4-yl}-N-phenylpropanamide …
Matched Description: … 3-Methyl-thiofentanyl is a [fentanyl] analog and an opioid analgesic that works by inducing central nervous …
Bermekimab
Bermekimab is under investigation in clinical trial NCT01384630 (Safety, Pharmacokinetics, and Efficacy of RA-18C3 in Subjects With Moderate to Severe Psoriasis).
Investigational
AVI-7537
AVI-7537 is an antisense molecule that binds to the Ebola virus mRNA to prevent the viral replication. AVI-7537 is under investigation in clinical trial NCT01593072 (A Study to Assess the Safety, Tolerability and Pharmacokinetics of AVI-7537 in Healthy Adult Volunteers).
Investigational
Matched Synonyms: … 5'-GCCATGGTTTTTTCTCAGG-3' …
L-2-aminopimelic acid
Experimental
Matched Synonyms: … 2-Aminopimelic acid ... (2S)-2-Aminoheptanedioic acid ... (S)-2-aminoheptanedioic acid …
Matched Name: … L-2-aminopimelic acid …
Matched Iupac: … (2S)-2-aminoheptanedioic acid …
Matched Name: … L-2-aminopimelic acid …
Matched Iupac: … (2S)-2-aminoheptanedioic acid …
ABT-639
ABT-639 is under investigation in clinical trial NCT01345045 (A Multicenter Study Comparing the Analgesic Effects and Safety of ABT-639 Compared to Placebo in Subjects With Diabetic Neuropathic Pain).
Investigational
Matched Iupac: … 5-[(8aR)-octahydropyrrolo[1,2-a]pyrazine-2-carbonyl]-4-chloro-2-fluoro-N-(2-fluorophenyl)benzene-1-sulfonamide …
3-Chloroalaninate
Experimental
Matched Name: … 3-Chloroalaninate …
Matched Iupac: … (2S)-2-azaniumyl-3-chloropropanoate …
Matched Iupac: … (2S)-2-azaniumyl-3-chloropropanoate …
3,5-Diiodotyrosine
A product from the iodination of MONOIODOTYROSINE. In the biosynthesis of thyroid hormones, diiodotyrosine residues are coupled with other monoiodotyrosine or diiodotyrosine residues to form T4 or T3 thyroid hormones (THYROXINE and TRIIODOTHYRONINE). [PubChem]
Experimental
Matched Iupac: … (2S)-2-amino-3-(4-hydroxy-3,5-diiodophenyl)propanoic acid …
BNT162b3
The BNT162b3 vaccine is the latest addition to BioNTech and partner Pfizer’s mRNA COVID-19 vaccine program. Similar to BNT162b2, BNT162b3 uses a nucleoside-modified RNA (modRNA) technology. Pfizer and BioNTech deemed this compound as promising in preclinical trials and have decided to initiate further testing of it. As such, BNT162b3 has...
Investigational
Spanlecortemlocel
Investigational
Eluvixtamab
Investigational
5-(2-METHOXYPHENYL)-2-FUROIC ACID
Experimental
Matched Name: … 5-(2-METHOXYPHENYL)-2-FUROIC ACID …
Matched Iupac: … 5-(2-methoxyphenyl)furan-2-carboxylic acid …
Matched Iupac: … 5-(2-methoxyphenyl)furan-2-carboxylic acid …
[2(R,S)-2-Sulfanylheptanoyl]-Phe-Ala
Experimental
Matched Name: … [2(R,S)-2-Sulfanylheptanoyl]-Phe-Ala …
Matched Iupac: … (2S)-2-[(2S)-3-phenyl-2-[(2S)-2-sulfanylheptanamido]propanamido]propanoic acid …
Matched Iupac: … (2S)-2-[(2S)-3-phenyl-2-[(2S)-2-sulfanylheptanamido]propanamido]propanoic acid …
1-(2,2'-bithiophen-5-yl)methanamine
Experimental
Inhibitor Bea428
Experimental
Matched Iupac: … [4-(pyridin-3-yl)phenyl]methoxy})hexanediimidic acid ... (2R,3R,4R,5R)-3,4-dihydroxy-N,N'-bis[(1S)-2-methyl-1-(methyl-C-hydroxycarbonimidoyl)propyl]-2,5-bis({ …
Inhibitor BEA409
Experimental
Matched Iupac: … (2R,3R,4R,5R)-3,4-dihydroxy-N,N'-bis[(1S)-2-methyl-1-(methylcarbamoyl)propyl]-2,5-bis({[4-(thiophen-3 …
A-674563
Experimental
Matched Synonyms: … (alphaS)-alpha-(((5-(3-Methyl-1H-indazol-5-yl)-3-pyridinyl)oxy)methyl)benzeneethanamine …
Matched Iupac: … (2S)-1-{[5-(3-methyl-1H-indazol-5-yl)pyridin-3-yl]oxy}-3-phenylpropan-2-amine …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Iupac: … (2S)-1-{[5-(3-methyl-1H-indazol-5-yl)pyridin-3-yl]oxy}-3-phenylpropan-2-amine …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
AN2898
AN2898 is under investigation in clinical trial NCT01301508 (Efficacy and Safety of AN2898 and AN2728 Topical Ointments to Treat Mild-to-moderate Atopic Dermatitis).
Investigational
Matched Iupac: … 4-[(1-hydroxy-1,3-dihydro-2,1-benzoxaborol-5-yl)oxy]benzene-1,2-dicarbonitrile …
GSK-2981278
GSK-2981278 is under investigation in clinical trial NCT03004846 (A Study of GSK2981278 Ointment in Subjects With Plaque Psoriasis).
Investigational
Matched Iupac: … N-(4-ethylphenyl)-3-(hydroxymethyl)-N-(2-methylpropyl)-4-[(oxan-4-yl)methoxy]benzene-1-sulfonamide …
OS2966
OS2966 is a humanized integrin β1 (CD29) blocking antibody currently evaluated for the treatment of acute myeloid leukemia, glioblastoma and ovarian cancer.[A254561, L47351]
Investigational
RLYB212
RLYB212 is a human monoclonal antibody against Antigen-1A Immunoglobulin (HPA-1A). It is currently being developed by Rallybio for the prevention of fetal and neonatal alloimmune thrombocytopenia.
Investigational
ER2001
Investigational
Displaying drugs 8376 - 8400 of 11304 in total