Displaying drugs 8426 - 8450 of 10807 in total
Avizakimab
Avizakimab is under investigation in clinical trial NCT03371251 (Study of BOS161721 in Systemic Lupus Erythematosus (SLE) Patients on a Background of Limited Standard of Care).
Investigational
2-amino-8-methyl-4(1H)-quinazolinone
Experimental
Matched Name: … 2-amino-8-methyl-4(1H)-quinazolinone …
Matched Iupac: … 2-amino-8-methyl-1,4-dihydroquinazolin-4-one …
Matched Iupac: … 2-amino-8-methyl-1,4-dihydroquinazolin-4-one …
9-(4-hydroxybutyl)-N2-phenylguanine
9-(4-hydroxybutyl)-N2-phenylguanine is a solid. This compound belongs to the hypoxanthines. These are compounds containing the purine derivative 1H-purin-6(9H)-one. 9-(4-hydroxybutyl)-n2-phenylguanine is known to target thymidine kinase.
Experimental
Matched Iupac: … 9-(4-hydroxybutyl)-2-(phenylamino)-6,9-dihydro-1H-purin-6-one …
2-Dimethylamino-Ethyl-Diphosphate
Experimental
Matched Name: … 2-Dimethylamino-Ethyl-Diphosphate …
Matched Iupac: … ({[2-(dimethylamino)ethoxy](hydroxy)phosphoryl}oxy)phosphonic acid …
Matched Iupac: … ({[2-(dimethylamino)ethoxy](hydroxy)phosphoryl}oxy)phosphonic acid …
(R)-1-Para-Nitro-Phenyl-2-Azido-Ethanol
Experimental
Matched Name: … (R)-1-Para-Nitro-Phenyl-2-Azido-Ethanol …
Matched Iupac: … (1R)-2-azido-1-(4-nitrophenyl)ethan-1-ol …
Matched Iupac: … (1R)-2-azido-1-(4-nitrophenyl)ethan-1-ol …
4-(2,5-DIAMINO-5-HYDROXY-PENTYL)-PHENOL
Experimental
Tralesinidase alfa
Tralesinidase alfa is a chimeric fusion protein comprised of recombinant human NAGLU and a modified human insulin-like growth factor 2. It is being investigated for the treatment of mucopolysaccharidosis type IIIB (MPS IIIB), also known as Sanfilippo syndrome B.
Investigational
Matched Synonyms: … Alpha-N-acetyglucosaminidase-insulin-like-growth-factor-2 fusion protein ... Recombinant human alpha-N-acetylglucosaminidase-insulin-like growth factor-2 …
Matched Description: … fusion protein comprised of recombinant human NAGLU and a modified human insulin-like growth factor 2. …
Matched Description: … fusion protein comprised of recombinant human NAGLU and a modified human insulin-like growth factor 2. …
6-[(Z)-Amino(Imino)Methyl]-N-[4-(Aminomethyl)Phenyl]-4-(Pyrimidin-2-Ylamino)-2-Naphthamide
Experimental
Matched Name: … 6-[(Z)-Amino(Imino)Methyl]-N-[4-(Aminomethyl)Phenyl]-4-(Pyrimidin-2-Ylamino)-2-Naphthamide …
Matched Iupac: … N-[4-(aminomethyl)phenyl]-6-carbamimidoyl-4-[(pyrimidin-2-yl)amino]naphthalene-2-carboxamide …
Matched Iupac: … N-[4-(aminomethyl)phenyl]-6-carbamimidoyl-4-[(pyrimidin-2-yl)amino]naphthalene-2-carboxamide …
(7R,8R)-8-(2,4,5-trifluorophenyl)-6,7,8,9-tetrahydroimidazo[1,2-a:4,5-c']dipyridin-7-amine
Experimental
Matched Iupac: … (11R,12R)-11-(2,4,5-trifluorophenyl)-1,5,8-triazatricyclo[7.4.0.0^{2,7}]trideca-2(7),3,5,8-tetraen-12 …
6-amino-2-[(thiophen-2-ylmethyl)amino]-1,7-dihydro-8H-imidazo[4,5-g]quinazolin-8-one
Experimental
Matched Name: … 6-amino-2-[(thiophen-2-ylmethyl)amino]-1,7-dihydro-8H-imidazo[4,5-g]quinazolin-8-one …
Matched Iupac: … 6-amino-2-{[(thiophen-2-yl)methyl]amino}-1H,7H,8H-imidazo[4,5-g]quinazolin-8-one …
Matched Iupac: … 6-amino-2-{[(thiophen-2-yl)methyl]amino}-1H,7H,8H-imidazo[4,5-g]quinazolin-8-one …
(S)-Mandelic acid
Experimental
Matched Synonyms: … (S)-2-Hydroxy-2-phenylacetic acid …
Matched Iupac: … (2S)-2-hydroxy-2-phenylacetic acid …
Matched Iupac: … (2S)-2-hydroxy-2-phenylacetic acid …
Serelaxin
Recombinant human relaxin is a hormone produced during pregnancy that facilitates the birth process by causing a softening and lengthening of the cervix and the pubic symphysis (the place where the pubic bones come together).It is a heterodimer protein secreted by the corpus luteum and placenta during pregnancy.
Investigational
Matched Synonyms: … Human relaxin 2 (relaxin h2) …
Seliciclib
R-roscovitine (Seliciclib or CYC202) is a cyclin-dependent kinase (CDK) inhibitor that preferentially inhibits multiple enzyme targets including CDK2, CDK7 and CDK9, which alter the growth phase of treated cells. Developed by Cyclacel, seliciclib is being researched for the treatment of non-small cell lung cancer (NSCLC), leukemia, HIV infection, herpes simplex...
Investigational
Matched Synonyms: … 2-(R)-(1-ethyl-2-hydroxyethylamino)-6-benzylamino-9-isopropylpurine …
Matched Iupac: … (2R)-2-{[6-(benzylamino)-9-(propan-2-yl)-9H-purin-2-yl]amino}butan-1-ol …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Iupac: … (2R)-2-{[6-(benzylamino)-9-(propan-2-yl)-9H-purin-2-yl]amino}butan-1-ol …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
5-(2-methylpiperazine-1-sulfonyl)isoquinoline
Experimental
Matched Synonyms: … 1-(5-Isoquinolinesulfonyl)-2-methylpiperazine ... 1-(5-Isoquinolinylsulfonyl)-2-methylpiperazine …
Matched Name: … 5-(2-methylpiperazine-1-sulfonyl)isoquinoline …
Matched Iupac: … 5-[(2-methylpiperazin-1-yl)sulfonyl]isoquinoline …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Name: … 5-(2-methylpiperazine-1-sulfonyl)isoquinoline …
Matched Iupac: … 5-[(2-methylpiperazin-1-yl)sulfonyl]isoquinoline …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
5-Chloryl-2,4,6-quinazolinetriamine
Experimental
1-(4-thiophen-2-ylphenyl)methanamine
Experimental
Matched Name: … 1-(4-thiophen-2-ylphenyl)methanamine …
Matched Iupac: … 1-[4-(thiophen-2-yl)phenyl]methanamine …
Matched Iupac: … 1-[4-(thiophen-2-yl)phenyl]methanamine …
Methyl salicylate 2-ethylbutyrate
Experimental
Matched Synonyms: … Salicylic acid, methyl ester, 2-ethylbutyrate …
Matched Name: … Methyl salicylate 2-ethylbutyrate …
Matched Iupac: … methyl 2-[(2-ethylbutanoyl)oxy]benzoate …
Matched Name: … Methyl salicylate 2-ethylbutyrate …
Matched Iupac: … methyl 2-[(2-ethylbutanoyl)oxy]benzoate …
OSI-027
OSI-027 has been used in trials studying the treatment of Any Solid Tumor or Lymphoma.
Investigational
Matched Synonyms: … CYCLOHEXANECARBOXYLIC ACID, 4-(4-AMINO-5-(7-METHOXY-1H-INDOL-2-YL)IMIDAZO(5,1-F)(1,2,4)TRIAZIN-7-YL)- …
Matched Iupac: … (1r,4r)-4-[4-amino-5-(7-methoxy-1H-indol-2-yl)imidazo[4,3-f][1,2,4]triazin-7-yl]cyclohexane-1-carboxylic …
Matched Iupac: … (1r,4r)-4-[4-amino-5-(7-methoxy-1H-indol-2-yl)imidazo[4,3-f][1,2,4]triazin-7-yl]cyclohexane-1-carboxylic …
Citarinostat
Citarinostat is under investigation in clinical trial NCT02886065 (A Study of PVX-410, a Cancer Vaccine, and Citarinostat +/- Lenalidomide for Smoldering MM).
Investigational
Matched Synonyms: … (2-((2-chlorophenyl)(phenyl)amino)-N-(7-(hydroxyamino)-7-oxoheptyl)pyrimidine-5-carboxamide) …
Matched Iupac: … 7-({2-[(2-chlorophenyl)(phenyl)amino]pyrimidin-5-yl}formamido)-N-hydroxyheptanamide …
Matched Iupac: … 7-({2-[(2-chlorophenyl)(phenyl)amino]pyrimidin-5-yl}formamido)-N-hydroxyheptanamide …
P-(2'-Iodo-5'-Thenoyl)Hydrotropic Acid
Experimental
Matched Name: … P-(2'-Iodo-5'-Thenoyl)Hydrotropic Acid …
Matched Iupac: … (2S)-2-[4-(5-iodothiophene-2-carbonyl)phenyl]propanoic acid …
Matched Iupac: … (2S)-2-[4-(5-iodothiophene-2-carbonyl)phenyl]propanoic acid …
Benzo[B]Thiophene-2-Carboxamidine
Experimental
Matched Name: … Benzo[B]Thiophene-2-Carboxamidine …
Matched Iupac: … [amino(1-benzothiophen-2-yl)methylidene]azanium …
Matched Iupac: … [amino(1-benzothiophen-2-yl)methylidene]azanium …
2-chloro-5-nitro-N-phenylbenzamide
Experimental
Matched Name: … 2-chloro-5-nitro-N-phenylbenzamide …
Matched Iupac: … 2-chloro-5-nitro-N-phenylbenzamide …
Matched Iupac: … 2-chloro-5-nitro-N-phenylbenzamide …
4-(2-AMINOPHENYL)-4-OXOBUTANOIC ACID
Experimental
Matched Name: … 4-(2-AMINOPHENYL)-4-OXOBUTANOIC ACID …
Matched Iupac: … 4-(2-aminophenyl)-4-oxobutanoic acid …
Matched Iupac: … 4-(2-aminophenyl)-4-oxobutanoic acid …
Tianeptine
Tianeptine is a drug used primarily in the treatment of major depressive disorder and has been studied in the treatment of irritable bowel syndrome (IBS) . Structurally, it is classified as a tricyclic antidepressant (TCA), however, it possesses different pharmacological properties than typical tricyclic antidepressants .
Tianeptine was discovered and...
Investigational
Matched Iupac: … -hexaen-2-yl}amino)heptanoic acid ... 7-({6-chloro-10-methyl-9,9-dioxo-9lambda6-thia-10-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(15),3(8),4,6,11,13 …
Matched Salts cas: … 30123-17-2 …
Matched Salts cas: … 30123-17-2 …
Sulfamoxole
Sulfamoxole is an antibacterial in the sulfonamide class.
Experimental
Matched Synonyms: … 4,5-Dimethyl-2-sulfanilamidooxazole ... N1-(4,5-Dimethyl-2-oxazolyl)sulfanilamide ... 2-(p-Aminobenzenesulfonamido)-4,5-dimethyloxazole …
Matched Iupac: … 4-amino-N-(4,5-dimethyl-1,3-oxazol-2-yl)benzene-1-sulfonamide …
Matched Iupac: … 4-amino-N-(4,5-dimethyl-1,3-oxazol-2-yl)benzene-1-sulfonamide …
Displaying drugs 8426 - 8450 of 10807 in total