Displaying drugs 8451 - 8475 of 11209 in total
Carbon black
Produced by the incomplete combustion of hydrocarbons, carbon black is an insoluble pigment with demonstrated adverse effects on pulmonary function. Upon inhalation, carbon black has been reported to trigger an inflammatory response in the lung tissue and has been linked to carcinogenicity.[A263406, A263411, A263416]
Investigational
Matched Synonyms: … BLACK 2 ... D&C black no. 2 ... DC BLACK NO. 2 …
Parasorbic acid
Sole constituent of "Vogelbeerol" oil obtained by steam distillation of the acidified juice of the ripe berries of the mountain ash.
Experimental
Matched Synonyms: … 2-Hexen-5,1-olide ... 5-Hydroxy-2-hexenoic acid lactone ... (S)-(+)-5,6-Dihydro-6-methyl-2H-pyran-2-one …
Matched Iupac: … (6S)-6-methyl-5,6-dihydro-2H-pyran-2-one …
Matched Iupac: … (6S)-6-methyl-5,6-dihydro-2H-pyran-2-one …
N-acetyl-alpha-D-glucosamine
The N-acetyl derivative of glucosamine.
Experimental
Matched Synonyms: … 2-(acetylamino)-2-deoxy-A-D-glucopyranose ... 2-(acetylamino)-2-deoxy-α-D-glucopyranose …
Matched Iupac: … N-[(2S,3R,4R,5S,6R)-2,4,5-trihydroxy-6-(hydroxymethyl)oxan-3-yl]acetamide …
Matched Iupac: … N-[(2S,3R,4R,5S,6R)-2,4,5-trihydroxy-6-(hydroxymethyl)oxan-3-yl]acetamide …
Denenicokin
Denenicokin is under investigation in clinical trial NCT01152788 (Phase II Study of Interleukin-21 (rIL-21) vs Dacarbazine (DTIC) in Patients With Metastatic or Recurrent Melanoma).
Investigational
N-T-Butylhydroxylamine
Investigational
Matched Synonyms: … 2-hydroxylamino-2-methylpropane ... N-hydroxy-2-methyl-2-propanamine …
Darleukin
Investigational
N-(2-Aminoethyl)-1-aziridineethanamine
First described in the literature in 2004, N-(2-Aminoethyl)-1-aziridineethanamine is an experimental angiotensin converting enzyme 2 inhibitor investigated for its use in treating cardiovascular disease and its activity against Severe Acute Respiratory Syndrome (SARS).
Experimental
Matched Synonyms: … N-(2-((2-Aminoethyl)amino)ethyl)aziridine ... N-(2-aminoethyl)-1 aziridine-ethanamine …
Matched Name: … N-(2-Aminoethyl)-1-aziridineethanamine …
Matched Iupac: … (2-aminoethyl)[2-(aziridin-1-yl)ethyl]amine …
Matched Description: … First described in the literature in 2004, N-(2-Aminoethyl)-1-aziridineethanamine is an experimental ... angiotensin converting enzyme 2 inhibitor investigated for its use in treating cardiovascular disease …
Matched Name: … N-(2-Aminoethyl)-1-aziridineethanamine …
Matched Iupac: … (2-aminoethyl)[2-(aziridin-1-yl)ethyl]amine …
Matched Description: … First described in the literature in 2004, N-(2-Aminoethyl)-1-aziridineethanamine is an experimental ... angiotensin converting enzyme 2 inhibitor investigated for its use in treating cardiovascular disease …
2-(2-METHYLPHENYL)-1H-INDOLE-5-CARBOXIMIDAMIDE
Experimental
Matched Name: … 2-(2-METHYLPHENYL)-1H-INDOLE-5-CARBOXIMIDAMIDE …
Matched Iupac: … 2-(2-methylphenyl)-1H-indole-5-carboximidamide …
Matched Iupac: … 2-(2-methylphenyl)-1H-indole-5-carboximidamide …
Ropidoxuridine
Ropidoxuridine is a novel, orally available, thymidine analogue and prodrug for IUdR, which demonstrated a survival advantage in Phase II studies in anaplastic astrocytoma, a type of brain tumor.
Investigational
Matched Synonyms: … 5-iodo-2-pyrimidinone-2'-deoxyribose ... 1-(2-DEOXY-.BETA.-D-ERYTHRO-PENTOFURANOSYL)-5-IODOPYRIMIDIN-2(1H)-ONE ... 2(1H)-PYRIMIDINONE, 1-(2-DEOXY-.BETA.-D-ERYTHRO-PENTOFURANOSYL)-5-IODO- …
Matched Iupac: … 1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-iodo-1,2-dihydropyrimidin-2-one …
Matched Iupac: … 1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-iodo-1,2-dihydropyrimidin-2-one …
Eflepedocokin alfa
Eflepedocokin alfa is a recombinant IL-22-Fc fusion protein manufactured in Chinese hamster ovary cells that is composed of 2 human interleukin 22 (IL-22) molecules linked to an immunoglobulin constant region (IgG2-Fc).[A225706, L27661] It is being developed by Evive Biotech (previously known as Generon BioMed Inc).
Investigational
Matched Description: … recombinant IL-22-Fc fusion protein manufactured in Chinese hamster ovary cells that is composed of 2 …
Pepinemab
Pepinemab is under investigation in clinical trial NCT03769155 (VX15/2503 With or Without Ipilimumab and/or Nivolumab in Patients With Resectable Stage IIIB-D Melanoma).
Investigational
3-Nitrophenylboronic Acid
Experimental
Matched Name: … 3-Nitrophenylboronic Acid …
Matched Iupac: … (3-nitrophenyl)boronic acid …
Matched Iupac: … (3-nitrophenyl)boronic acid …
3,6,9,12,15,18-HEXAOXAICOSANE
Experimental
1,2-Dimethoxyethane
Experimental
GSK2256098
GSK2256098 is under investigation in clinical trial NCT02523014 (Vismodegib and FAK Inhibitor GSK2256098 in Treating Patients With Progressive Meningiomas).
Investigational
Matched Iupac: … 2-[(5-chloro-2-{[3-methyl-1-(propan-2-yl)-1H-pyrazol-5-yl]amino}pyridin-4-yl)amino]-N-methoxybenzamide …
Cyclic GMP
Cyclic guanosine monophosphate (Cyclic GMP) is a guanine nucleotide containing one phosphate group which is esterified to the sugar moiety in both the 3'- and 5'-positions. It is a cellular regulatory agent and has been described as a second messenger. Its levels increase in response to a variety of hormones,...
Experimental
Matched Synonyms: … 3',5'-cyclic GMP ... Guanosine 3',5'-cyclic phosphate ... Guanosine 3',5'-cyclic monophosphate …
Matched Iupac: … 9-[(4aR,6R,7R,7aS)-2,7-dihydroxy-2-oxo-hexahydro-2lambda5-furo[3,2-d][1,3,2]dioxaphosphinin-6-yl]-2-amino …
Matched Description: … guanine nucleotide containing one phosphate group which is esterified to the sugar moiety in both the 3& …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Iupac: … 9-[(4aR,6R,7R,7aS)-2,7-dihydroxy-2-oxo-hexahydro-2lambda5-furo[3,2-d][1,3,2]dioxaphosphinin-6-yl]-2-amino …
Matched Description: … guanine nucleotide containing one phosphate group which is esterified to the sugar moiety in both the 3& …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Ivuxolimab
Ivuxolimab is under investigation in clinical trial NCT02554812 (A Study of Avelumab in Combination With Other Cancer Immunotherapies in Advanced Malignancies (JAVELIN Medley)).
Investigational
Saruplase
Experimental
Acimtamig
Acimtamig is a tetravalent bispecific chimeric anti-human CD30 x anti-human CD16A recombinant antibody construct.
Investigational
Matched Synonyms: … -(human FcγRIIIa receptor) (human heavy chain V-D-J region) fusion protein with peptide linker (GGS)3 ... with immunoglobulin anti-(human CD30 antigen) (human-Mus musculus single-chain Fv fragment VL-(GGS)3- …
Etigilimab
Etigilimab is under investigation in clinical trial NCT04761198 (A Study of Etigilimab and Nivolumab in Subjects With Locally Advanced or Metastatic Tumors.).
Investigational
6-Hydroxypropylthymine
Experimental
Matched Synonyms: … 6–(3-hydroxypropyl)thymine …
Matched Iupac: … 6-(3-hydroxypropyl)-5-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione …
Matched Iupac: … 6-(3-hydroxypropyl)-5-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione …
alpha-Methylleucine
Experimental
Matched Synonyms: … (S)-2-Methylleucine ... 2-Methyl-L-leucine …
Matched Iupac: … (2S)-2-amino-2,4-dimethylpentanoic acid …
Matched Iupac: … (2S)-2-amino-2,4-dimethylpentanoic acid …
(R)-Mandelic acid
Experimental
Matched Synonyms: … (2R)-2-hydroxy-2-phenylacetic acid ... (R)-2-Hydroxy-2-phenylacetic acid ... D-2-phenylglycolic acid …
Matched Iupac: … (2R)-2-hydroxy-2-phenylacetic acid …
Matched Iupac: … (2R)-2-hydroxy-2-phenylacetic acid …
ALT-P7
Investigational
Displaying drugs 8451 - 8475 of 11209 in total