Displaying drugs 851 - 875 of 1202 in total
MDX-210
Investigational
Matched Synonyms: … Bispecific antibody 520c9x22 …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Ubamatamab
Ubamatamab is under investigation in clinical trial NCT03564340 (Study of REGN4018 Administered Alone or in Combination With Cemiplimab in Adult Patients With Recurrent Ovarian Cancer or Other Recurrent Mucin-16 Expressing (MUC16+) Cancers).
Investigational
Matched Synonyms: … Anti-muc16/cd3 bite antibody regn4018 ... Bispecific t-cell engager antibody regn4018 …
Volociximab
Investigational
Matched Synonyms: … Anti-alpha5beta1 integrin monoclonal antibody …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Bemarituzumab
Bemarituzumab is under investigation in clinical trial NCT03694522 (A Study of Bemarituzumab (FPA144) Combined With Modified FOLFOX6 (Mfolfox6) in Gastric/gastroesophageal Junction Cancer (FIGHT)).
Investigational
Matched Synonyms: … Anti-fgfr2 monoclonal antibody fpa144 …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
ATG-101
ATG-101 is a novel PD-L1/4-1BB bispecific antibody that was designed to block the binding of immunosuppressive PD-1/PD-L1 and conditionally induce 4-1BB stimulation, thus activating anti-tumor immune effectors, while delivering enhanced anti-tumor activity, with an improved safety profile.
Investigational
Matched Synonyms: … PD-L1/4-1BB bispecific antibody …
Matched Description: … PD-1/PD-L1 and conditionally induce 4-1BB stimulation, thus activating anti-tumor immune effectors, ... ATG-101 is a novel PD-L1/4-1BB bispecific antibody that was designed to block the binding of immunosuppressive …
Matched Description: … PD-1/PD-L1 and conditionally induce 4-1BB stimulation, thus activating anti-tumor immune effectors, ... ATG-101 is a novel PD-L1/4-1BB bispecific antibody that was designed to block the binding of immunosuppressive …
Tidutamab
Tidutamab is under investigation in clinical trial NCT04590781 (Safety and Efficacy of Xmab18087 ± Pembrolizumab in Advanced Merkel Cell Carcinoma or Extensive-stage Small Cell Lung Cancer).
Investigational
Matched Synonyms: … Anti-sstr2/cd3 monoclonal antibody xmab18087 …
Matched Description: … Tidutamab is under investigation in clinical trial NCT04590781 (Safety and Efficacy of Xmab18087 ± Pembrolizumab …
Matched Description: … Tidutamab is under investigation in clinical trial NCT04590781 (Safety and Efficacy of Xmab18087 ± Pembrolizumab …
Zilovertamab
Investigational
Matched Synonyms: … Immunoglobulin g1, anti-(human receptor tyrosine kinase ror-1) (human-mus musculus monoclonal uc-961 ... .gamma.1-chain), disulfide with human-mus musculus monoclonal uc-961 .kappa. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Vixarelimab
Vixarelimab is under investigation in clinical trial NCT03816891 (A Study to Assess the Efficacy, Safety, and Tolerability of KPL-716 in Reducing Pruritus in Prurigo Nodularis).
Investigational
Matched Synonyms: … (human monoclonal kpl-716 .gamma.-chain), disulfide with human monoclonal kpl-716 .lambda. ... Immunoglobulin g (234-proline,303-glutamine), anti-(human oncostatin m receptor subunit .beta.) …
Matched Description: … Vixarelimab is under investigation in clinical trial NCT03816891 (A Study to Assess the Efficacy, Safety, and …
Matched Description: … Vixarelimab is under investigation in clinical trial NCT03816891 (A Study to Assess the Efficacy, Safety, and …
Denecimig
Delpacibart is a humanized, bispecific, bivalent monoclonal antibody against coagulation factor 9.
Investigational
Matched Synonyms: … Immunoglobulin G4 [230-proline,de-449-lysine], anti-(human blood-coagulation factor IX) (human clone ... .229′)-bis(disulfide) with anti-(human bl ... 0365-0001-9985 γ4-chain), disulfide with human clone 0365-0001-9985 κ-chain, (228.fwdarw.226′),(231.fwdarw …
Matched Description: … Delpacibart is a humanized, bispecific, bivalent monoclonal antibody against coagulation factor 9. …
Matched Description: … Delpacibart is a humanized, bispecific, bivalent monoclonal antibody against coagulation factor 9. …
Povidone
Povidone, also known as polyvinylpyrrolidone (PVP) or polyvidone, is a synthetic water-soluble polymer made from the monomer N-vinylpyrrolidone used as a binder in many pharmaceutical tablets and lubricant in eye drops. It is also used in many technical applications with various roles as an adhesive, additive, and emulsifier. When in...
Approved
Withdrawn
Matched Description: … water-soluble polymer made from the monomer N-vinylpyrrolidone used as a binder in many pharmaceutical tablets and ... It is also used in many technical applications with various roles as an adhesive, additive, and emulsifier ... antiseptic properties where the iodine, a bactericidal component, mainly contributes to this effect, and …
Matched Mixtures name: … Redness reliever and Lubricant ... Rohto Sun and Sport ... Meijer Advanced Redness and Irritation Relief …
Matched Products: … iVizia Lubricant Eye for Severe Night Dry Eyes …
Matched Mixtures name: … Redness reliever and Lubricant ... Rohto Sun and Sport ... Meijer Advanced Redness and Irritation Relief …
Matched Products: … iVizia Lubricant Eye for Severe Night Dry Eyes …
Stapokibart
Stapokibart is under investigation in clinical trial NCT06424470 (Study on the Treatment of Prurigo Nodularis With Stapokibart Injection).
Investigational
Matched Synonyms: … Immunoglobulin G4 [227-proline], anti-(human interleukin 4 receptor subunit α) (human-Mus musculus monoclonal ... CM310 γ4-chain), disulfide with human-Mus musculus monoclonal CM310 κ-chain, dimer …
Obinepitide
Obinepitide is a synthetic analogue of two natural human hormones, PYY and Pancreatic Polypeptide, which normally are released during a meal. These hormones are known to play a role in the regulation of food intake and appetite in man as satiety signal from the GI-tract to the CNS. In obinepitide,...
Investigational
Matched Synonyms: … (34-L-glutamine)pancreatic hormone (human) …
Matched Description: … Obinepitide is a synthetic analogue of two natural human hormones, PYY and Pancreatic Polypeptide, which ... These hormones are known to play a role in the regulation of food intake and appetite in man as satiety …
Matched Description: … Obinepitide is a synthetic analogue of two natural human hormones, PYY and Pancreatic Polypeptide, which ... These hormones are known to play a role in the regulation of food intake and appetite in man as satiety …
Humate-P
Investigational
Matched Name: … Humate-P …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Retifanlimab
Retifanlimab is a humanized IgG4 kappa monoclonal antibody that binds to the programmed death receptor-1 (PD-1), blocking PD-1 interaction with its ligands, programmed death-ligand 1 (PD-L1) and programmed death-ligand 2 (PD-L2). By blocking the PD-1/PD-L1/2 pathway, retifanlimab potentiates T-cell activity and boosts the immune response against cancer cells. Other monoclonal...
Approved
Investigational
Matched Synonyms: … Anti-PD-1 monoclonal antibody MGA012 …
Matched Description: … -1 (PD-1), blocking PD-1 interaction with its ligands, programmed death-ligand 1 (PD-L1) and programmed ... By blocking the PD-1/PD-L1/2 pathway, retifanlimab potentiates T-cell activity and boosts the immune ... [L45603] Other monoclonal antibodies that block PD-1 include [pembrolizumab], [nivolumab] and [cemiplimab …
Matched Categories: … MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Programmed Death Receptor-1 Blocking Antibody …
Matched Description: … -1 (PD-1), blocking PD-1 interaction with its ligands, programmed death-ligand 1 (PD-L1) and programmed ... By blocking the PD-1/PD-L1/2 pathway, retifanlimab potentiates T-cell activity and boosts the immune ... [L45603] Other monoclonal antibodies that block PD-1 include [pembrolizumab], [nivolumab] and [cemiplimab …
Matched Categories: … MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Programmed Death Receptor-1 Blocking Antibody …
Endostar
Endostar is under investigation for the treatment of Nasopharyngeal Carcinoma. Endostar has been investigated for the treatment of Non-small Cell Lung Cancer.
Investigational
Matched Synonyms: … Recombinant human endostatin protein ... N-TERMINAL-MGGSHHHHH-ENDOSTATIN (HUMAN RECOMBINANT) …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Tuvirumab
Investigational
Matched Synonyms: … Immunoglobulin g 1 (human monoclonal pe1-1 anti-hepatitis b virus surface antigen), disulfide with human ... Ostavir human anti-hepatitis b ... Immunoglobulin g 1 (human monoclonal pe1-1 anti-hepatitis b virus surface antigen), disulfide with human …
Aldesleukin
Aldesleukin, a lymphokine, is produced by recombinant DNA technology using a genetically engineered E. coli strain containing an analog of the human interleukin-2 gene. Genetic engineering techniques were used to modify the human IL-2 gene, and the resulting expression clone encodes a modified human interleukin-2. This recombinant form differs from...
Approved
Matched Synonyms: … Recombinant human interleukin-2 ... Recombinant interleukin-2 human ... 125-L-serine-2-133-interleukin 2 (human reduced) …
Matched Description: … Genetic engineering techniques were used to modify the human IL-2 gene, and the resulting expression ... clone encodes a modified human interleukin-2. ... recombinant DNA technology using a genetically engineered E. coli strain containing an analog of the human …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Intercellular Signaling Peptides and Proteins …
Matched Description: … Genetic engineering techniques were used to modify the human IL-2 gene, and the resulting expression ... clone encodes a modified human interleukin-2. ... recombinant DNA technology using a genetically engineered E. coli strain containing an analog of the human …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Intercellular Signaling Peptides and Proteins …
Pagibaximab
Investigational
Matched Synonyms: … ), DISULFIDE WITH HUMAN-MOUSE MONOCLONAL .KAPPA. ... chain), disulfide with human-mouse monoclonal κ-chain, dimer ... HEAVY CHAIN), DISULFIDE WITH HUMAN MOUSE MONOCLONAL HU96 110 .KAPPA. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Livmoniplimab
Livmoniplimab is under investigation in clinical trial NCT06109272 (A Study to Assess the Dose, Adverse Events, and Change in Disease Activity of Livmoniplimab as an Intravenous (IV) Solution in Combination With Budigalimab as an IV Solution in Adult Participants With Hepatocellular Carcinoma (HCC)).
Investigational
Matched Synonyms: … (human monoclonal abbv-151 .gamma.4-chain), disulfide with human monoclonal abbv-151 .kappa. ... Immunoglobulin g4 (234-proline), anti-(human protein garp-transforming growth factor .beta.1 complex) …
Matched Description: … Livmoniplimab is under investigation in clinical trial NCT06109272 (A Study to Assess the Dose, Adverse Events, and …
Matched Description: … Livmoniplimab is under investigation in clinical trial NCT06109272 (A Study to Assess the Dose, Adverse Events, and …
Marstacimab
Marstacimab is a human Monoclonal Antibody Directed Against Tissue Factor Pathway Inhibitor currently being developed by Pfizer for the treatment of hemophilia A and hemophilia B.
Investigational
Matched Synonyms: … Immunoglobulin g1, anti-(human tissue factor pathway inhibitor) (human monoclonal pf-06741086 .gamma.1 ... -chain), disulfide with human monoclonal pf-06741086 .lambda. ... Immunoglobulin g1-lambda, anti-(human tissue factor pathway inhibitor (tfpi, extrinsic pathway inhibitor …
Matched Description: … being developed by Pfizer for the treatment of hemophilia A and hemophilia B. ... Marstacimab is a human Monoclonal Antibody Directed Against Tissue Factor Pathway Inhibitor currently …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … being developed by Pfizer for the treatment of hemophilia A and hemophilia B. ... Marstacimab is a human Monoclonal Antibody Directed Against Tissue Factor Pathway Inhibitor currently …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Finotonlimab
Finotonlimab is under investigation in clinical trial NCT04560894 (SCT-I10A Plus SCT510 Versus Sorafenib as First-line Therapy for Advanced Hepatocellular Carcinoma).
Investigational
Matched Synonyms: … Immunoglobulin g4 (226-proline), anti-(human programmed cell death 1) (human-mus musculus monoclonal ... sct-i10a .gamma.4-chain), disulfide with human-mus musculus monoclonal sct-i10a .kappa. …
Clesrovimab
Clesrovimab is under investigation in clinical trial NCT04938830 (Clesrovimab (MK-1654) in Infants and Children at Increased Risk for Severe Respiratory Syncytial Virus (RSV) Disease (MK-1654-007)).
Investigational
Matched Synonyms: … f protein) (human monoclonal rb1 .gamma.1-chain), disulfide with human monoclonal rb1 .kappa. ... Immunoglobulin g1 (262-tyrosine,264-threonine,266-glutamic acid), anti-(human respiratory syncytial virus …
Matched Description: … Clesrovimab is under investigation in clinical trial NCT04938830 (Clesrovimab (MK-1654) in Infants and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … Clesrovimab is under investigation in clinical trial NCT04938830 (Clesrovimab (MK-1654) in Infants and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Teropavimab
Teropavimab is under investigation in clinical trial NCT05729568 (A Study of GS-5423 and GS-2872 in Combination With Capsid Inhibitor Lenacapavir in Virologically Suppressed Adults With HIV-1 Infection).
Investigational
Matched Synonyms: … ) (human monoclonal 8c11-62a12 .gamma.1-chain), disulfide with human monoclonal 8c11-62a12 .kappa. ... Immunoglobulin g1 (434-leucine,440-serine), anti-(human immunodeficiency virus 1 envelope protein gp120env …
Matched Description: … Teropavimab is under investigation in clinical trial NCT05729568 (A Study of GS-5423 and GS-2872 in Combination …
Matched Description: … Teropavimab is under investigation in clinical trial NCT05729568 (A Study of GS-5423 and GS-2872 in Combination …
Depelestat
Investigational
Matched Synonyms: … Proteinase inhibitor m/nei (synthetic human) ... Recombinant human neutrophil inhibitor (hne) ... Human recombinant neutrophil elastase inhibitor, homologue of the second kunitz domain of inter-alpha-trypsin …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Alidornase alfa
Investigational
Matched Synonyms: … Deoxyribonuclease (synthetic human), amide with 1,2-ethanediamine …
Displaying drugs 851 - 875 of 1202 in total