Displaying drugs 851 - 875 of 2889 in total
Trimesic acid
Experimental
Matched Synonyms: … Trimesinic acid ... Trimesitinic acid ... 5-carboxyisophthalic acid …
Matched Name: … Trimesic acid …
Matched Iupac: … benzene-1,3,5-tricarboxylic acid …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids …
Matched Name: … Trimesic acid …
Matched Iupac: … benzene-1,3,5-tricarboxylic acid …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids …
Palifermin
Palifermin is a recombinant human keratinocyte growth factor (KGF). It is 140 residues long, and is produced using E. coli.
Palifermin was granted FDA approval on 15 December 2004.
Approved
Matched Synonyms: … 24-163 fibroblast growth factor 7 (human) …
Matched Description: … It is 140 residues long, and is produced using E. coli. ... Palifermin is a recombinant human keratinocyte growth factor (KGF). …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Matched Description: … It is 140 residues long, and is produced using E. coli. ... Palifermin is a recombinant human keratinocyte growth factor (KGF). …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
OptPA
Optimized tPA (OptPA; W253R/R275S-tPA) is an engineered variant of tPA designed to exhibit reduced neurotoxicity.
Investigational
Matched Synonyms: … Pptimized human tissue-type plasminogen activator …
Citraconic acid
Citraconic acid is one of the isomeric dicarboxylic acids produced by the distillation of citric acid, or as metabolites by microorganisms, cis-CH3-C(CO2H)=CHCO2H; the trans-isomer is mesaconic acid.
Experimental
Matched Synonyms: … 2-methylmaleic acid ... Methylmaleic acid ... α-methylmaleic acid …
Matched Name: … Citraconic acid …
Matched Iupac: … (2Z)-2-methylbut-2-enedioic acid …
Matched Description: … Citraconic acid is one of the isomeric dicarboxylic acids produced by the distillation of citric acid ... , or as metabolites by microorganisms, cis-CH3-C(CO2H)=CHCO2H; the trans-isomer is mesaconic acid. …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids ... Dicarboxylic Acids …
Matched Name: … Citraconic acid …
Matched Iupac: … (2Z)-2-methylbut-2-enedioic acid …
Matched Description: … Citraconic acid is one of the isomeric dicarboxylic acids produced by the distillation of citric acid ... , or as metabolites by microorganisms, cis-CH3-C(CO2H)=CHCO2H; the trans-isomer is mesaconic acid. …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids ... Dicarboxylic Acids …
Dehydrocholic acid
Dehydrocholic acid is a synthetic bile acid that was prepared from the oxidation of cholic acid with chromic acid . It has been used for stimulation of biliary lipid secretion. The use of dehydrocholic acid in over-the-counter products has been discontinued by Health Canada.
Approved
Investigational
Matched Synonyms: … Dehydrocholic acid ... 3,7,12-triketocholanic acid ... 3,7,12-trioxocholanic acid …
Matched Name: … Dehydrocholic acid …
Matched Iupac: … 9aS,9bS,11aR)-9a,11a-dimethyl-4,7,11-trioxo-hexadecahydro-1H-cyclopenta[a]phenanthren-1-yl]pentanoic acid …
Matched Description: … chromic acid [A33022]. ... Dehydrocholic acid is a synthetic bile acid that was prepared from the oxidation of cholic acid with ... The use of dehydrocholic acid in over-the-counter products has been discontinued by Health Canada. …
Matched Categories: … Bile Acids and Salts ... Cholagogues and Choleretics ... Cholic Acids …
Matched Name: … Dehydrocholic acid …
Matched Iupac: … 9aS,9bS,11aR)-9a,11a-dimethyl-4,7,11-trioxo-hexadecahydro-1H-cyclopenta[a]phenanthren-1-yl]pentanoic acid …
Matched Description: … chromic acid [A33022]. ... Dehydrocholic acid is a synthetic bile acid that was prepared from the oxidation of cholic acid with ... The use of dehydrocholic acid in over-the-counter products has been discontinued by Health Canada. …
Matched Categories: … Bile Acids and Salts ... Cholagogues and Choleretics ... Cholic Acids …
3',3-diselenodipropionic acid
Investigational
Matched Synonyms: … Diselenodipropionic acid ... 3',3-diseleno dipropionic acid ... Diseleno-3,3'-dipropionic acid …
Matched Name: … 3',3-diselenodipropionic acid …
Matched Iupac: … 3-[(2-carboxyethyl)diselanyl]propanoic acid …
Matched Name: … 3',3-diselenodipropionic acid …
Matched Iupac: … 3-[(2-carboxyethyl)diselanyl]propanoic acid …
Myristic acid
Experimental
Matched Synonyms: … Tetradecanoic acid ... N-tetradecanoic acid ... N-tetradecan-1-oic acid …
Matched Name: … Myristic acid …
Matched Iupac: … tetradecanoic acid …
Matched Categories: … Fatty Acids ... Myristic Acids …
Matched Name: … Myristic acid …
Matched Iupac: … tetradecanoic acid …
Matched Categories: … Fatty Acids ... Myristic Acids …
Ivonescimab
Ivonescimab is under investigation in clinical trial NCT05184712 (Phase 3 Clinical Study of AK112 for NSCLC Patients).
Investigational
Matched Synonyms: … IMMUNOGLOBULIN G1 (240-ALANINE,241-ALANINE), ANTI-(HUMAN VASCULAR ENDOTHELIAL GROWTH FACTOR A) (HUMAN-MUS ... .GAMMA.1-CHAIN) FUSION PROTEIN WITH PEPTIDE LINKER (GGGS)4 FUSION PROTEIN WITH IMMUNOGLOBULIN ANTI-(HUMAN …
Ponsegromab
Ponsegromab is under investigation in clinical trial NCT05492500 (A Study of Ponsegromab in People With Heart Failure).
Investigational
Matched Synonyms: … ) (human-mus musculus monoclonal pf-06946860 .gamma.1-chain), disulfide with human-mus musculus monoclonal ... Immunoglobulin g1 (237-alanine,238-alanine,240-alanine), anti-(human growth differentiation factor 15 …
D-Lactic acid
A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
Experimental
Matched Synonyms: … (−)-lactic acid ... (R)-lactic acid ... (R)-(−)-lactic acid …
Matched Name: … D-Lactic acid …
Matched Iupac: … (2R)-2-hydroxypropanoic acid …
Matched Categories: … Hydroxy Acids ... Carboxylic Acids …
Matched Name: … D-Lactic acid …
Matched Iupac: … (2R)-2-hydroxypropanoic acid …
Matched Categories: … Hydroxy Acids ... Carboxylic Acids …
Phenylpyruvic acid
Experimental
Matched Synonyms: … 3-phenylpyruvic acid ... Phenylpyruvic acid ... β-phenylpyruvic acid …
Matched Name: … Phenylpyruvic acid …
Matched Iupac: … 2-oxo-3-phenylpropanoic acid …
Matched Categories: … Keto Acids ... Carboxylic Acids ... Acids, Carbocyclic …
Matched Name: … Phenylpyruvic acid …
Matched Iupac: … 2-oxo-3-phenylpropanoic acid …
Matched Categories: … Keto Acids ... Carboxylic Acids ... Acids, Carbocyclic …
Isoferulic acid
Experimental
Matched Synonyms: … Hesperetic acid ... Isoferulic acid …
Matched Name: … Isoferulic acid …
Matched Iupac: … (2E)-3-(3-hydroxy-4-methoxyphenyl)prop-2-enoic acid …
Matched Categories: … Carboxylic Acids ... Acids, Carbocyclic …
Matched Name: … Isoferulic acid …
Matched Iupac: … (2E)-3-(3-hydroxy-4-methoxyphenyl)prop-2-enoic acid …
Matched Categories: … Carboxylic Acids ... Acids, Carbocyclic …
Oteracil
Oteracil is an adjunct to antineoplastic therapy, used to reduce the toxic side effects associated with chemotherapy. Approved by the European Medicines Agency (EMA) in March 2011, Oteracil is available in combination with DB09257 and DB09256 within the commercially available product "Teysuno". The main active ingredient in Teysuno is DB09256,...
Approved
Matched Synonyms: … Oxonic Acid ... 5-azaorotic acid ... Allantoxanic acid …
Matched Iupac: … 4,6-dioxo-1,4,5,6-tetrahydro-1,3,5-triazine-2-carboxylic acid …
Matched Description: … European Medicines Agency (EMA) in March 2011, Oteracil is available in combination with [DB09257] and ... By mimicking a class of compounds called "pyrimidines" that are essential components of RNA and DNA, ... 5-FU is able to insert itself into strands of DNA and RNA, thereby halting the replication process necessary …
Matched Iupac: … 4,6-dioxo-1,4,5,6-tetrahydro-1,3,5-triazine-2-carboxylic acid …
Matched Description: … European Medicines Agency (EMA) in March 2011, Oteracil is available in combination with [DB09257] and ... By mimicking a class of compounds called "pyrimidines" that are essential components of RNA and DNA, ... 5-FU is able to insert itself into strands of DNA and RNA, thereby halting the replication process necessary …
Madecassic acid
Experimental
Matched Synonyms: … Brahmic acid ... 6β-hydroxyasiatic acid …
Matched Name: … Madecassic acid …
Matched Iupac: … 9,12a-hexamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-4a-carboxylic acid …
Matched Name: … Madecassic acid …
Matched Iupac: … 9,12a-hexamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-4a-carboxylic acid …
gamma-Hydroxybutyric acid
Gamma hydroxybutyric acid, commonly abbreviated GHB, is a therapeutic drug which is illegal in multiple countries. It is currently regulated in the US and sold by Jazz Pharmaceuticals under the name Xyrem. However, it is important to note that GHB is a designated Orphan drug (in 1985). Today Xyrem is...
Approved
Illicit
Investigational
Matched Synonyms: … 3-carboxypropoxy acid ... oxy-n-butyric acid ... 4-hydroxy-butyric acid …
Matched Name: … gamma-Hydroxybutyric acid …
Matched Iupac: … 4-hydroxybutanoic acid …
Matched Description: … Gamma hydroxybutyric acid, commonly abbreviated GHB, is a therapeutic drug which is illegal in multiple ... It is currently regulated in the US and sold by Jazz Pharmaceuticals under the name Xyrem. ... Today Xyrem is a Schedule III drug; however GHB remains a Schedule I drug and the illicit use of Xyrem …
Matched Categories: … Acids, Acyclic ... Fatty Acids ... Hydroxy Acids ... Carboxylic Acids ... Fatty Acids, Volatile …
Matched Name: … gamma-Hydroxybutyric acid …
Matched Iupac: … 4-hydroxybutanoic acid …
Matched Description: … Gamma hydroxybutyric acid, commonly abbreviated GHB, is a therapeutic drug which is illegal in multiple ... It is currently regulated in the US and sold by Jazz Pharmaceuticals under the name Xyrem. ... Today Xyrem is a Schedule III drug; however GHB remains a Schedule I drug and the illicit use of Xyrem …
Matched Categories: … Acids, Acyclic ... Fatty Acids ... Hydroxy Acids ... Carboxylic Acids ... Fatty Acids, Volatile …
5-aminonaphthalene-2-sulfonic acid
Experimental
Matched Synonyms: … 1,6-Cleve's acid ... Cleve's β-acid ... 1-naphthylamine-6-sulfonic acid …
Matched Name: … 5-aminonaphthalene-2-sulfonic acid …
Matched Iupac: … 5-aminonaphthalene-2-sulfonic acid …
Matched Name: … 5-aminonaphthalene-2-sulfonic acid …
Matched Iupac: … 5-aminonaphthalene-2-sulfonic acid …
Lutikizumab
Lutikizumab is under investigation in clinical trial NCT02087904 (A Study Evaluating the Safety, Efficacy, and Pharmacodynamic Effects of ABT-981 in Patients With Knee Osteoarthritis).
Investigational
Matched Synonyms: … (synthetic human a-1234138 heavy chain), disulfide with synthetic human a-1234138 light chain, dimer …
Matched Description: … Lutikizumab is under investigation in clinical trial NCT02087904 (A Study Evaluating the Safety, Efficacy, and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … Lutikizumab is under investigation in clinical trial NCT02087904 (A Study Evaluating the Safety, Efficacy, and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Resamirigene bilparvovec
AT132 is under investigation in clinical trial NCT03199469 (Gene Transfer Clinical Study in X-linked Myotubular Myopathy).
Investigational
Matched Synonyms: … DNA (synthetic adeno-associated virus 8 vector AT132 human myotubularin cDNA-specifying) ... Non-replicating adeno-associated viral vector, serotype 8, expressing human myotubularin gene …
Phenylbutyric acid
Phenylbutyric acid is a fatty acid and a derivative of butyric acid naturally produced by colonic bacteria fermentation. It demonstrates a number of cellular and biological effects, such as relieving inflammation and acting as a chemical chaperone. It is used to treat genetic metabolic syndromes, neuropathies, and urea cycle disorders.[L386,L42105]
Approved
Investigational
Matched Synonyms: … Benzenebutyric acid ... 4-phenylbutyric acid ... 4-Phenyl-n-butyric acid …
Matched Name: … Phenylbutyric acid …
Matched Iupac: … 4-phenylbutanoic acid …
Matched Description: … Phenylbutyric acid is a fatty acid and a derivative of [butyric acid] naturally produced by colonic bacteria ... It demonstrates a number of cellular and biological effects, such as relieving inflammation and acting ... [A249035] It is used to treat genetic metabolic syndromes, neuropathies, and urea cycle disorders. …
Matched Categories: … Acids, Carbocyclic ... Alimentary Tract and Metabolism ... Carboxylic Acids ... sodium phenylbutyrate and ursodoxicoltaurine ... Various Alimentary Tract and Metabolism Products …
Matched Name: … Phenylbutyric acid …
Matched Iupac: … 4-phenylbutanoic acid …
Matched Description: … Phenylbutyric acid is a fatty acid and a derivative of [butyric acid] naturally produced by colonic bacteria ... It demonstrates a number of cellular and biological effects, such as relieving inflammation and acting ... [A249035] It is used to treat genetic metabolic syndromes, neuropathies, and urea cycle disorders. …
Matched Categories: … Acids, Carbocyclic ... Alimentary Tract and Metabolism ... Carboxylic Acids ... sodium phenylbutyrate and ursodoxicoltaurine ... Various Alimentary Tract and Metabolism Products …
CR002
CR002 is a novel investigational fully human monoclonal antibody that blocks the activity of excess platelet-derived growth factor-D (PDGF-D), a target shown to play a role in kidney inflammation. This is a novel therapeutic approach to treat kidney inflammation.
Investigational
Matched Synonyms: … Human monoclonal antibody against platelet-derived growth factor D …
Matched Description: … CR002 is a novel investigational fully human monoclonal antibody that blocks the activity of excess platelet-derived …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … CR002 is a novel investigational fully human monoclonal antibody that blocks the activity of excess platelet-derived …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Vestronidase alfa
Vestronidase alfa, or vestronidase alfa-vjbk, is a recombinant human lysosomal beta glucuronidase that is a purified enzyme produced by recombinant DNA technology in a Chinese hamster ovary cell line. The enzyme is a homotetramer consisted of 4 monomers with 629 amino acids, and holds the same amino acid sequence as...
Approved
Investigational
Matched Synonyms: … Recombinant human beta-glucuronidase …
Matched Description: … The enzyme is a homotetramer consisted of 4 monomers with 629 amino acids, and holds the same amino acid ... sequence as human beta-glucuronidase (GUS) [FDA Label]. ... Vestronidase alfa, or vestronidase alfa-vjbk, is a recombinant human lysosomal beta glucuronidase that …
Matched Categories: … Enzymes and Coenzymes ... Alimentary Tract and Metabolism …
Matched Description: … The enzyme is a homotetramer consisted of 4 monomers with 629 amino acids, and holds the same amino acid ... sequence as human beta-glucuronidase (GUS) [FDA Label]. ... Vestronidase alfa, or vestronidase alfa-vjbk, is a recombinant human lysosomal beta glucuronidase that …
Matched Categories: … Enzymes and Coenzymes ... Alimentary Tract and Metabolism …
Spheramine
Investigational
Matched Synonyms: … Allogeneic human retinal pigment epithelial cells on gelatin microcarriers …
Cyclohexanepropanoic acid
Experimental
Matched Synonyms: … 3-Cyclohexanepropionic acid ... 3-Cyclohexylpropanoic acid ... 3-Cyclohexylpropionic acid …
Matched Name: … Cyclohexanepropanoic acid …
Matched Iupac: … 3-cyclohexylpropanoic acid …
Matched Name: … Cyclohexanepropanoic acid …
Matched Iupac: … 3-cyclohexylpropanoic acid …
Salicylamide O-acetic acid
Experimental
Matched Synonyms: … Salamidacetic acid ... Salicylamide-2-acetic acid ... 2-Carbamoylphenoxyacetic acid …
Matched Name: … Salicylamide O-acetic acid …
Matched Iupac: … 2-(2-carbamoylphenoxy)acetic acid …
Matched Name: … Salicylamide O-acetic acid …
Matched Iupac: … 2-(2-carbamoylphenoxy)acetic acid …
Displaying drugs 851 - 875 of 2889 in total