Displaying drugs 851 - 875 of 1287 in total
Chelerythrine
A benzophenanthridine alkaloid evaluated as a kinase-inhibitor.
Investigational
Matched Description: … A benzophenanthridine alkaloid evaluated as a kinase-inhibitor.[A252982] …
PD-169316
PD-169316 is a p38 MAP kinase inhibitor.
Investigational
Matched Description: … PD-169316 is a p38 MAP kinase inhibitor.[A253062] …
PD-173952
PD-173952 is a potent Myt1 kinase inhibitor.
Investigational
Matched Description: … PD-173952 is a potent Myt1 kinase inhibitor.[A253067] …
Brasofensine
Brasofensine is an orally administered dopamine reuptake inhibitor being developed for the treatment of Parkinson's Disease. Phase I/II trials for brasofensine have been completed in the U.K. In November 2001, NeuroSearch confirmed that the drug's development was discontinued in favor of NS 2230.
Investigational
Matched Description: … Brasofensine is an orally administered dopamine reuptake inhibitor being developed for the treatment …
R-95845
R-95845 is an inhibitor of HIV-1 reverse transcriptase.
Experimental
Matched Description: … R-95845 is an inhibitor of HIV-1 reverse transcriptase. …
NSC-663284
NSC-663284 is a potent quinolinedione Cdc25 phosphatase inhibitor.
Investigational
Matched Description: … NSC-663284 is a potent quinolinedione Cdc25 phosphatase inhibitor.[A253052] …
GFH-925
GFH-925 is an irreversibly covalent inhibitor of KRAS G12C.
Investigational
Matched Description: … GFH-925 is an irreversibly covalent inhibitor of KRAS G12C. …
GB1211
GB1211 is an orally active galectin-3 (Gal-3) inhibitor.
Investigational
Matched Description: … GB1211 is an orally active galectin-3 (Gal-3) inhibitor. …
CKD-504
CKD-504 is a novel, selective histone deacetylase 6 inhibitor.
Investigational
Matched Description: … CKD-504 is a novel, selective histone deacetylase 6 inhibitor. …
Clorgiline
An antidepressive agent and monoamine oxidase inhibitor related to PARGYLINE.
Experimental
Matched Description: … An antidepressive agent and monoamine oxidase inhibitor related to PARGYLINE. …
LY-2183240
LY-2183240 is an inhibitor of endocannabinoid reuptake/breakdown.
Investigational
Matched Description: … LY-2183240 is an inhibitor of endocannabinoid reuptake/breakdown.[A253037] …
JAB-21822
JAB-21822 is an oral small-molecule KRAS G12C inhibitor.
Investigational
Matched Description: … JAB-21822 is an oral small-molecule KRAS G12C inhibitor. …
MK-0731
MK-0731 is a kinesin spindle protein inhibitor and antineoplastic agent.
Experimental
Matched Description: … MK-0731 is a kinesin spindle protein inhibitor and antineoplastic agent. …
CA-170
CA-170 is a selective, small molecule inhibitor of PD-L1.
Investigational
Matched Description: … CA-170 is a selective, small molecule inhibitor of PD-L1. …
DMP-777
DMP-777 is a selective inhibitor of polymorphonuclear leukocyte (PMN) elastase.
Investigational
Matched Description: … DMP-777 is a selective inhibitor of polymorphonuclear leukocyte (PMN) elastase. …
APL-030
APL-030 is a orally-active small molecule inhibitor of GCN2.
Investigational
Matched Description: … APL-030 is a orally-active small molecule inhibitor of GCN2. …
Tipifarnib
Tipifarnib (R-115777) is a substance that is being studied in the treatment of acute myeloid leukemia (AML) and other types of cancer. It belongs to the family of drugs called farnesyltransferase inhibitors. It is also called Zarnestra. In June 2005, the FDA issued a Not Approvable Letter for Zarnestra.
Investigational
Oxypurinol
Oxypurinol, an inhibitor of xanthine oxidase, is a metabolite of allopurinol.
Investigational
Matched Description: … Oxypurinol, an inhibitor of xanthine oxidase, is a metabolite of allopurinol. …
PD-98059
PD-98059 is an inhibitor of MAP-kinase kinase activation.
Investigational
Matched Description: … PD-98059 is an inhibitor of MAP-kinase kinase activation.[A253072] …
PIK-75
PIK-75 is a preferential p110 alpha/gamma PI3K inhibitor.
Investigational
Matched Description: … PIK-75 is a preferential p110 alpha/gamma PI3K inhibitor.[A253097] …
Aprinocarsen
Aprinocarsen is a specific antisense oligonucleotide inhibitor of protein kinase C-alpha.
Investigational
Matched Description: … Aprinocarsen is a specific antisense oligonucleotide inhibitor of protein kinase C-alpha. …
JNJ-27390467
JNJ-27390467 is a potent, nonpeptide inhibitor of human mast cell tryptase.
Experimental
Matched Description: … JNJ-27390467 is a potent, nonpeptide inhibitor of human mast cell tryptase. …
NNC-55-0396 free base
NNC-55-0396 is a T-type Ca(2+) channel inhibitor.
Investigational
Matched Description: … NNC-55-0396 is a T-type Ca(2+) channel inhibitor.[A253047] …
PI-103
PI-103 is an inhibitor of p110α of class I PI3K.
Investigational
Matched Description: … PI-103 is an inhibitor of p110α of class I PI3K.[A253092] …
EI-1071
EI-1071 is a selective Colony Stimulating Factor-1 Receptor kinase inhibitor.
Investigational
Matched Description: … EI-1071 is a selective Colony Stimulating Factor-1 Receptor kinase inhibitor. …
Displaying drugs 851 - 875 of 1287 in total