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Displaying drugs 8826 - 8850 of 10730 in total
Terameprocol
Terameprocol has been investigated for the treatment of Brain and Central Nervous System Tumors.
Investigational
Matched Iupac: … 4-[(2R,3S)-3-[(3,4-dimethoxyphenyl)methyl]-2-methylbutyl]-1,2-dimethoxybenzene …
Adegramotide
Investigational
Ifenprodil
N-methyl-D-aspartate (NMDA) receptors (NMDARs) are members of the ionotropic glutamate receptor family, with key roles in brain development and neurological function.[A220118, A220128] NMDARs are heterotetramers that typically involve a dimer of dimers of both GluN1 and GluN2A-D subunits, with each subunit itself composed of an N-terminal domain (NTD), a ligand-binding...
Investigational
Withdrawn
Matched Iupac: … 4-[2-(4-benzylpiperidin-1-yl)-1-hydroxypropyl]phenol …
Matched Description: … Ifenprodil is being investigated for its potential utility in treating COVID-19 in an ongoing phase 2b/3 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Description: … Ifenprodil is being investigated for its potential utility in treating COVID-19 in an ongoing phase 2b/3 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Niceritrol
Experimental
Matched Iupac: … 3-(pyridine-3-carbonyloxy)-2,2-bis[(pyridine-3-carbonyloxy)methyl]propyl pyridine-3-carboxylate …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
AZD-7762
AZD7762 has been investigated for the treatment of Cancer, Solid Tumors, and Advanced Solid Malignancies.
Investigational
Matched Iupac: … 3-(carbamoylamino)-5-(3-fluorophenyl)-N-[(3S)-piperidin-3-yl]thiophene-2-carboxamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
WRR-99
Experimental
Matched Iupac: … (3S)-3-hydroxy-3-{[(1R)-1-[(3-methylbutyl)carbamoyl]-3-phenylpropyl]carbamoyl}propanoic acid …
Barnidipine
Barnidipine is a long-acting novel calcium antagonist that belongs to the dihydropyridine (DHP) group of calcium channel blockers. Used in the treatment of hypertension, barnidipine displays high affinity for the calcium channels of the smooth muscle cells in the vascular wall and selectivity against cardiovascular L-type calcium channels . Barnidipine...
Experimental
Matched Iupac: … 3-(3S)-1-benzylpyrrolidin-3-yl 5-methyl (4S)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate …
Matched Description: … The active component is composed of a single optical isomer (*3'S, 4S* configuration), which is the most ... moderate hypertension, the antihypertensive response from barnidipine treatment was maintained after a 1- …
Matched Salts cas: … 104757-53-1 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Description: … The active component is composed of a single optical isomer (*3'S, 4S* configuration), which is the most ... moderate hypertension, the antihypertensive response from barnidipine treatment was maintained after a 1- …
Matched Salts cas: … 104757-53-1 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Nisoxetine
Nisoxetine is a selective norepinephrine reuptake inhibitor (SNRI) developed in the 1970s. It was originally investigated as an antidepressant but has no current clinical applications aside from being a research standard SNRI. It has been used to research obesity and energy balance, and exerts some local analgesia effects.
Experimental
Matched Iupac: … [3-(2-methoxyphenoxy)-3-phenylpropyl](methyl)amine …
Methylmethionine chloride
Methylmethionine chloride may be useful in helping the healing of gastric ulcers. In Japan, it is used as an over the counter product for gastrointestinal health support. It is also called "Vitamin U", but it is not a true vitamin.
Experimental
Matched Iupac: … [(3S)-3-amino-3-carboxypropyl]dimethylsulfanium chloride …
TN-201
TN-201 is a gene therapy comprising a native AAV9 capsid with a genomic cassette containing a cardiomyocyte-specific promoter and the wild-type human MYBPC3 gene.
Investigational
beta-Hydroxyisovaleric acid
beta-Hydroxyisovaleric acid is under investigation in clinical trial NCT03018496 (Investigating the Effects of Beta-Hydroxy-Beta-Methylbutyrate on Glucose Handling in Older and Younger Men.).
Investigational
Matched Iupac: … 3-hydroxy-3-methylbutanoic acid …
2-[5,6-BIS-(4-METHOXY-PHENYL)-FURO[2,3-D]PYRIMIDIN-4-YLAMINO]-ETHANOL
Experimental
Matched Iupac: … 2-{[5,6-bis(4-methoxyphenyl)furo[2,3-d]pyrimidin-4-yl]amino}ethan-1-ol …
TRK-001
TRK-001 is an autologous regulatory T-cell therapy. It is being investigated for the prevention of graft rejection following solid organ transplantation.
Investigational
Lorecivivint
Lorecivivint is under investigation in clinical trial NCT03246399 (A Study of the Safety, Tolerability, and Pharmacokinetics of SM04690 Injectable Suspension Following Single Intradiscal Injection in Subjects With Degenerative Disc Disease).
Investigational
Matched Iupac: … N-(5-{3-[7-(3-fluorophenyl)-3H-imidazo[4,5-c]pyridin-2-yl]-1H-indazol-5-yl}pyridin-3-yl)-3-methylbutanamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Displaying drugs 8826 - 8850 of 10730 in total