Displaying drugs 8826 - 8850 of 11799 in total
Acebilustat
Acebilustat is under investigation in clinical trial NCT01748838 (Phase 1 Study Assessing the Safety and Tolerability of CTX-4430).
Investigational
Matched Iupac: … 4-{[(1S,4S)-5-({4-[4-(1,3-oxazol-2-yl)phenoxy]phenyl}methyl)-2,5-diazabicyclo[2.2.1]heptan-2-yl]methyl …
Indatuximab ravtansine
Indatuximab ravtansine is under investigation in clinical trial NCT01001442 (Safety and Dose Determining Multi-dose Study of BT062 in Patients With Relapsed or Refractory Multiple Myeloma).
Investigational
Matched Synonyms: … N2'-Deacetyl-N2'-[4-Methyl-4-(Oxobuthyldithio)-1-Oxopentyl]-Maytansine-Chimerized Anti-Cd138 Igg4 Monoclonal …
ABO-202
Investigational
N~2~-Succinylornithine
Experimental
Matched Iupac: … (2S)-5-amino-2-(3-carboxypropanamido)pentanoic acid …
Sulopenem etzadroxil
Sulopenem etzadroxil is under investigation in clinical trial NCT03354598 (Oral Sulopenem-etzadroxil/probenecid Versus Ciprofloxacin for Uncomplicated Urinary Tract Infection in Adult Women).
Investigational
Matched Iupac: … (1R,3S)-3-{[(5R,6S)-2-({[(2-ethylbutanoyl)oxy]methoxy}carbonyl)-6-[(1R)-1-hydroxyethyl]-7-oxo-4-thia- ... 1-azabicyclo[3.2.0]hept-2-en-3-yl]sulfanyl}thiolan-1-ium-1-olate …
4-phospho-L-threonic acid
Experimental
Matched Synonyms: … 4-O-phosphono-L-threonic acid …
Matched Name: … 4-phospho-L-threonic acid …
Matched Iupac: … (2R,3S)-2,3-dihydroxy-4-(phosphonooxy)butanoic acid …
Matched Name: … 4-phospho-L-threonic acid …
Matched Iupac: … (2R,3S)-2,3-dihydroxy-4-(phosphonooxy)butanoic acid …
4-Hydroxyphenylglycine
Experimental
Matched Synonyms: … (RS)-2-(4-hydroxyphenyl)glycine ... (+/-)-alpha-amino-4-hydroxybenzeneacetic acid …
Matched Name: … 4-Hydroxyphenylglycine …
Matched Iupac: … 2-amino-2-(4-hydroxyphenyl)acetic acid …
Matched Name: … 4-Hydroxyphenylglycine …
Matched Iupac: … 2-amino-2-(4-hydroxyphenyl)acetic acid …
4-Nitrophenyl Phosphate
Experimental
Matched Name: … 4-Nitrophenyl Phosphate …
Matched Iupac: … (4-nitrophenoxy)phosphonic acid …
Matched Iupac: … (4-nitrophenoxy)phosphonic acid …
Paclitaxel trevatide
Three paclitaxel molecules linked by a cleavable succinyl ester linkage to a brain peptide vector, Angiopep-2, conjugate named ANG1005.
Investigational
Japanese encephalitis vaccine (live, attenuated)
Experimental
Eritoran
Eritoran is a structural analogue of the lipid A portion of lipopolysaccharide (LPS). It is being developed by Eisai Research Institute of Boston for the treatment of severe sepsis.
Investigational
Matched Iupac: … {[(2R,3R,4R,5S,6R)-4-(decyloxy)-5-hydroxy-6-({[(2R,3R,4R,5S,6R)-4-{[(3R)-3-methoxydecyl]oxy}-6-(methoxymethyl ... )-3-[(11Z)-octadec-11-enamido]-5-(phosphonooxy)oxan-2-yl]oxy}methyl)-3-(3-oxotetradecanamido)oxan-2-yl …
Matched Categories: … Toll-Like Receptor 4, antagonists & inhibitors …
Matched Categories: … Toll-Like Receptor 4, antagonists & inhibitors …
Incadronic acid
Incadronate, or YM-175, is a nitrogen containing bisphosphonate. Along with being investigated to treat hypercalcemia of malignancy, it has also been investigated in the treatment of myeloma, leukemia, and other cancers.[A14426,A14431,A14427,A202769]
Incadronic acid was first described in the literature in 1991.
Experimental
Matched Salts cas: … 138330-18-4 …
Ivarmacitinib
Ivarmacitinib (SHR0302) is a selective inhibitor of Janus kinase 1 (JAK1) under investigation for the treatment of various immuno-inflammatory conditions. While ivarmactinib has yet to receive marketing authorization, as of February 2022 clinical trials are ongoing or completed evaluating its use in atopic dermatitis,[L40604,L40619,L40629] ankylosing spondylitis, rheumatoid arthritis, psoriatic arthritis,...
Experimental
Investigational
Matched Iupac: … (3aR,5S,6aS)-N-(3-methoxy-1,2,4-thiadiazol-5-yl)-5-[methyl({7H-pyrrolo[2,3-d]pyrimidin-4-yl})amino]-octahydrocyclopenta …
Matched Salts cas: … 1639419-51-4 …
Matched Salts cas: … 1639419-51-4 …
Reloxaliase
Reloxaliase is a crystalline formulation of oxalate decarboxylase derived from Bacillus Subtilis. Reloxaliase is under investigation in clinical trial NCT03456830 (Evaluate ALLN-177 in Patients With Enteric Hyperoxaluria).
Investigational
Hydrolyzed soy protein
Experimental
4-amino-5-aminomethyl-2-methylpyrimidine
Experimental
Matched Synonyms: … 2-Methyl-4-amino-5-aminomethylpyrimidine ... 4-Amino-2-methylpyrimidine-5-methylamine …
Matched Name: … 4-amino-5-aminomethyl-2-methylpyrimidine …
Matched Iupac: … 5-(aminomethyl)-2-methylpyrimidin-4-amine …
Matched Name: … 4-amino-5-aminomethyl-2-methylpyrimidine …
Matched Iupac: … 5-(aminomethyl)-2-methylpyrimidin-4-amine …
Vapreotide
Vapreotide is a synthetic octapeptide somatostatin analog. It was being studied for the treatment of cancer.
Experimental
Investigational
Matched Iupac: … (2R)-2-amino-N-[(4R,7S,10S,13R,16S,19R)-10-(4-aminobutyl)-4-{[(1S)-1-carbamoyl-2-(1H-indol-3-yl)ethyl ... ]carbamoyl}-16-[(4-hydroxyphenyl)methyl]-13-[(1H-indol-3-yl)methyl]-6,9,12,15,18-pentaoxo-7-(propan-2 ... -yl)-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-19-yl]-3-phenylpropanamide …
Indium In-111 satumomab pendetide
Tumor associated glycoprotein (TAG) 72 (B72.3) monoclonal antibody conjugated with Indium 111 for radioimaging colon tumors. Satumomab Pendetide (trade name: OncoScint®) is no longer commercially available.
Experimental
Withdrawn
Amdinocillin
Amidinopenicillanic acid derivative with broad spectrum antibacterial action. It is poorly absorbed if given orally and is used in urinary infections and typhus. Amdinocillin is not available in the United States.
Investigational
Withdrawn
Matched Iupac: … (2S,5R,6R)-6-{[(azepan-1-yl)methylidene]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2 …
Aniracetam
Compound with anti-depressive properties used as a mental performance enhancer.
Experimental
Matched Iupac: … 1-(4-methoxybenzoyl)pyrrolidin-2-one …
Cellotetraose
Experimental
Matched Iupac: … (2S,3R,4S,5S,6R)-2-{[(2R,3S,4R,5R,6S)-6-{[(2R,3S,4R,5R,6S)-4,5-dihydroxy-2-(hydroxymethyl)-6-{[(2R,3S ... ,4R,5R,6R)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxy}oxan-3-yl]oxy}-4,5-dihydroxy-2-(hydroxymethyl ... )oxan-3-yl]oxy}-6-(hydroxymethyl)oxane-3,4,5-triol …
Elsamitrucin
The cytostatic agent Elsamitrucin is a new fermentation product active in a variety of in vivo tumor models of murine and human origin. (PMID: 8150873)
Investigational
Matched Iupac: … 3-{[(2S,3R,4S,5S,6R)-3-{[(2R,3R,4R,5S,6R)-3-amino-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy}-4,5-dihydroxy …
Displaying drugs 8826 - 8850 of 11799 in total