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Displaying drugs 8901 - 8925 of 11724 in total
Alisertib is a novel aurora A kinase inhibitor under investigation for the treatment of various forms of cancer.
Investigational
Matched Iupac: … 4-{[13-chloro-10-(2-fluoro-6-methoxyphenyl)-3,5,9-triazatricyclo[9.4.0.0^{2,7}]pentadeca-1(15),2,4,6,9,11,13 ... -heptaen-4-yl]amino}-2-methoxybenzoic acid …
Matched Salts cas: … 1208255-63-3
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Ceftiofur is a third generation cephalosporin antibiotic, first described in 1987, and now used in veterinary medicine. It is marketed by pharmaceutical company Zoetis as Excenel, and is the active ingredient in that company's Specramast LC (lactating cow formula) product. It is resistant to hydrolysis by beta-lactamase, and has activity...
Vet approved
Matched Iupac: … (6R,7R)-7-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-3-[(furan-2-carbonylsulfanyl) ... methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Nona-arginine is under investigation in clinical trial NCT00264706 (PolyArginine Treated vEiN grafTs (PATENT)).
Investigational
Zoliflodacin has been used in trials studying the basic science and treatment of Gonorrhoea.
Investigational
Matched Iupac: … (4'R,6'S,7'S)-17'-fluoro-4',6'-dimethyl-13'-[(4S)-4-methyl-2-oxo-1,3-oxazolidin-3-yl]-5',15'-dioxa-2' ... ,14'-diazaspiro[1,5-diazinane-3,8'-tetracyclo[8.7.0.0^{2,7}.0^{12,16}]heptadecane]-1'(10'),11',13',16 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Experimental
Matched Iupac: … 5-[(2S,3R)-2-{[(1S,2S)-2-{[(S)-(tert-butoxy)(hydroxy)methyl]amino}-1-hydroxy-3-phenylpropyl]amino}-3- ... hydroxy-3-(pentylamino)propyl]-2-(carboxymethoxy)benzoic acid …
Experimental
Experimental
Matched Name: … 1-Methylcytosine …
Matched Iupac: … 4-amino-1-methyl-1,2-dihydropyrimidin-2-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Experimental
Matched Synonyms: … (1R)-1-phenylethanol …
Matched Name: … (R)-1-phenylethanol …
Matched Iupac: … (1R)-1-phenylethan-1-ol …
GSK159797 ('797) is an inhaled, longer-acting Beta2 agonist developed for the treatment of respiratory disease such as asthma and COPD.
Investigational
Ginsenosides are a class of steroid glycosides, and triterpene saponins, found exclusively in the plant genus Panax (ginseng). Ginsenosides have been the target of research, as they are viewed as the active compounds behind the claims of ginseng's efficacy. Because ginsenosides appear to affect multiple pathways, their effects are complex...
Nutraceutical
Matched Synonyms: … GRb 1
Matched Iupac: … )-2-{[(2R,3R,4S,5S,6R)-2-{[(1S,3aR,3bR,5aR,7S,9aR,9bR,11R,11aR)-11-hydroxy-3a,3b,6,6,9a-pentamethyl-1- ... -5-en-2-yl)-hexadecahydro-1H-cyclopenta[a]phenanthren-7-yl]oxy}-4,5-dihydroxy-6-(hydroxymethyl)oxan-3- …
Ginsenosides are a class of steroid glycosides, and triterpene saponins, found exclusively in the plant genus Panax (ginseng). Ginsenosides have been the target of research, as they are viewed as the active compounds behind the claims of ginseng's efficacy. Because ginsenosides appear to affect multiple pathways, their effects are complex...
Nutraceutical
L-deprenyl-D2 C-11 is under investigation in clinical trial NCT01701089 (A Study of RO4602522 in Patients With Alzheimer Disease and in Healthy Volunteers).
Investigational
Matched Iupac: … (11C)methyl[(2R)-1-phenylpropan-2-yl][(1,1-2H2)prop-2-yn-1-yl]amine …
BOS172722 is a novel and selective Monopolar spindle 1 (Mps1) kinase inhibitor identified as a potential anticancer agent. Normally, Mps1 supports the proper division of cancer cells, ensuring survival and replication. The key role of Mps1 in the growth of cancer cells renders it an appealing target for cancer treatment,...
Experimental
Matched Iupac: … N8-(2,2-dimethylpropyl)-N2-[2-ethoxy-4-(4-methyl-4H-1,2,4-triazol-3-yl)phenyl]-6-methylpyrido[3,4-d]pyrimidine …
Matched Description: … BOS172722 is a novel and selective Monopolar spindle 1 (Mps1) kinase inhibitor identified as a potential …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
TRC150094 is under investigation in clinical trial NCT03254446 (Safety and Efficacy Study of TRC150094 to Improve the CV Risk in Subjects With Diabetes, Dyslipidemia and Hypertension).
Investigational
Matched Iupac: … 3-{4-[(7-hydroxy-6-methyl-2,3-dihydro-1H-inden-4-yl)methyl]-3,5-dimethyl-1H-pyrazol-1-yl}propanoic acid …
siG12D LODER is under investigation in clinical trial NCT01676259 (A Phase 2 Study of Sig12d LODER in Combination With Chemotherapy in Patients With Locally Advanced Pancreatic Cancer).
Investigational
Investigational
Investigational
ST101 is a cell-penetrating peptide that disrupts the protein-protein interactions driving ATF5-regulated gene transcription.
Investigational
QXL138AM is a masked immunocytokine (MIC) comprised of an anti-CD138 immunoglobulin G1 antibody fused to interferon alpha 2a. It binds the CD138 protein on the surface of the tumour cells.
Investigational
Experimental
Illicit
Matched Name: … 1-Androstenediol …
Experimental
Matched Synonyms: … (S)-(+)-1-Bromo-2-propanol …
Matched Name: … (+)-1-bromo-2-propanol …
Matched Iupac: … (2S)-1-bromopropan-2-ol …
Experimental
Matched Name: … 1-Deaza-Adenosine …
Matched Iupac: … (2R,3R,4S,5R)-2-{7-amino-3H-imidazo[4,5-b]pyridin-3-yl}-5-(hydroxymethyl)oxolane-3,4-diol …
Experimental
Matched Iupac: … methyl (2R,3R)-3-{[3'-(aminomethyl)-[1,1'-biphenyl]-4-yl]formamido}-2-[(3-carbamimidoylphenyl)methyl] …
Chlorotoxin I-131 is investigated in clinical trials for treating brain cancer. Chlorotoxin I-131 binds to and reduces the activity of a matrix metalloproteinase (MMP) that regulates functioning of the chloride channels on cell membranes. Chlorotoxin is a small 36-amino-acid peptide that selectively binds to glioma cells but not normal brain...
Investigational
Matched Iupac: … {2-[4-(1,2-diphenylbutyl)phenoxy]ethyl}dimethylamine …
Tipifarnib (R-115777) is a substance that is being studied in the treatment of acute myeloid leukemia (AML) and other types of cancer. It belongs to the family of drugs called farnesyltransferase inhibitors. It is also called Zarnestra. In June 2005, the FDA issued a Not Approvable Letter for Zarnestra.
Investigational
Matched Iupac: … 6-[amino(4-chlorophenyl)(1-methyl-1H-imidazol-5-yl)methyl]-4-(3-chlorophenyl)-1-methyl-1,2-dihydroquinolin …
Displaying drugs 8901 - 8925 of 11724 in total