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Displaying drugs 8976 - 9000 of 12147 in total

Bisegliptin

Bisegliptin is a compound for the treatment of type 2 diabetes. It is an orally active, dipeptidyl peptidase-IV (DPPIV) inhibitor which lowers blood glucose levels by blocking the degradation of the hormone GLP-1 thereby stimulating glucose-dependent insulin secretion and lowering blood glucose levels without hypoglycemic effects.
Investigational
Matched Iupac: … ethyl 4-({2-[(2S,4S)-2-cyano-4-fluoropyrrolidin-1-yl]-2-oxoethyl}amino)bicyclo[2.2.2]octane-1-carboxylate …

Torcetrapib

Torcetrapib (CP-529414, Pfizer) was developed to treat hypercholesterolemia but its development was halted in 2006 when phase III studies showed excessive mortality in the treatment group receiving a combination of atorvastatin and the study drug.
Investigational
Matched Iupac: … ethyl (2R,4S)-4-({[3,5-bis(trifluoromethyl)phenyl]methyl}(methoxycarbonyl)amino)-2-ethyl-6-(trifluoromethyl …

Ibacitabine

Experimental
Matched Iupac: … 4-amino-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-iodo-1,2-dihydropyrimidin-2-one …

2'-deoxythioguanosine

Investigational
Matched Iupac: … 2-amino-9-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-6,9-dihydro-1H-purine-6-thione …

RRx-001

RRx-001 has been used in trials studying the treatment of Lymphomas, Brain Metastases, Cholangiocarcinoma, Colorectal Neoplasms, and Malignant Solid Tumor, among others.
Investigational

LY3884961

LY3884961 (previously PR001) is being developed by Prevail Therapeutics as a single-dose gene therapy for patients with Parkinson's disease and Gaucher disease.
Investigational

Gildeuretinol

Investigational

4-Aminohydrocinnamic Acid

Experimental
Matched Name: … 4-Aminohydrocinnamic Acid …
Matched Iupac: … 3-(4-aminophenyl)propanoic acid …

6-(2,6-DIMETHOXYPHENYL)PYRIDO[2,3-D]PYRIMIDINE-2,7-DIAMINE

Experimental

Maropitant

Maropitant, used as maropitant citrate, is a neurokinin receptor antagonist, which was developed by Zoetis specifically for the treatment of motion sickness and vomiting in dogs. It was approved by the FDA in 2007 for use in dogs, and more recently has also been approved for use in cats.
Vet approved
Matched Iupac: … (2S,3S)-N-[(5-tert-butyl-2-methoxyphenyl)methyl]-2-(diphenylmethyl)-1-azabicyclo[2.2.2]octan-3-amine …

D-4-hydroxyphenylglycine

Experimental
Matched Synonyms: … (R)-(4-hydroxyphenyl)glycine ... 4-hydroxy-d-phenylglycine ... D-4-hydroxyphenylglycine …
Matched Name: … D-4-hydroxyphenylglycine …
Matched Iupac: … (2R)-2-amino-2-(4-hydroxyphenyl)acetic acid …

N-acetylhistamine

Experimental
Matched Synonyms: … 4-(2-acetamidoethyl)imidazole ... 4-(2-acetylaminoethyl)imidazole ... 4-(beta-Acetylaminoethyl)imidazole …

3,5-Diiodotyrosine

A product from the iodination of MONOIODOTYROSINE. In the biosynthesis of thyroid hormones, diiodotyrosine residues are coupled with other monoiodotyrosine or diiodotyrosine residues to form T4 or T3 thyroid hormones (THYROXINE and TRIIODOTHYRONINE). [PubChem]
Experimental
Matched Iupac: … (2S)-2-amino-3-(4-hydroxy-3,5-diiodophenyl)propanoic acid …

BNT162b3

The BNT162b3 vaccine is the latest addition to BioNTech and partner Pfizer’s mRNA COVID-19 vaccine program. Similar to BNT162b2, BNT162b3 uses a nucleoside-modified RNA (modRNA) technology. Pfizer and BioNTech deemed this compound as promising in preclinical trials and have decided to initiate further testing of it. As such, BNT162b3 has...
Investigational

Aracytidine 5'-monophosphate

Experimental
Matched Iupac: … {[(2R,3S,4S,5R)-5-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}phosphonic …

7-(alpha-D-Glucopyranosyloxy)-4-methyl-2H-1-benzopyran-2-one

Experimental
Matched Synonyms: … 4-Methylumbelliferyl α-D-glucoside ... 4-Methylumbelliferyl a-D-glucopyranoside ... 7-(α-D-glucopyranosyloxy)-4-methyl-2H-1-benzopyran-2-one …
Matched Name: … 7-(alpha-D-Glucopyranosyloxy)-4-methyl-2H-1-benzopyran-2-one …
Matched Iupac: … 4-methyl-7-{[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-2H-chromen-2-one …

5'-Deoxy-5'-(Methylthio)-Tubercidin

Experimental
Matched Iupac: … (2R,3R,4S,5S)-2-{4-amino-7H-pyrrolo[2,3-d]pyrimidin-7-yl}-5-[(methylsulfanyl)methyl]oxolane-3,4-diol …

6-Deoxyerythronolide B

Experimental
Matched Iupac: … (3R,4S,5R,6S,7S,9R,11R,12S,13R,14R)-14-ethyl-4,6,12-trihydroxy-3,5,7,9,11,13-hexamethyl-1-oxacyclotetradecane …

5'-deoxy-5'-piperidin-1-ylthymidine

Experimental
Matched Iupac: … 1-[(2R,4S,5R)-4-hydroxy-5-[(piperidin-1-yl)methyl]oxolan-2-yl]-5-methyl-1,2,3,4-tetrahydropyrimidine- …

4-hydroxybenzoyl-CoA

Experimental
Matched Synonyms: … 4-hydroxybenzoyl-CoA ... 4-hydroxybenzoyl coenzyme A ... 4-hydroxybenzoyl-coenzyme A …
Matched Name: … 4-hydroxybenzoyl-CoA …
Matched Iupac: … {[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-2-({[hydroxy({hydroxy[(3R)-3-hydroxy-3-[(2-{[2-(4 ... hydroxybenzoylsulfanyl)ethyl]carbamoyl}ethyl)carbamoyl]-2,2-dimethylpropoxy]phosphoryl}oxy)phosphoryl]oxy}methyl)oxolan-3- …

Retinamidic acid

Investigational
Matched Synonyms: … N-4-carboxyphenylretinamide ... Retinamide, n-(4-carboxyphenyl)- ... Benzoic acid, 4-((15-oxoretin-15-yl)amino)- …
Matched Iupac: … 4-[(2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenamido]benzoic …

MK-1454

A synthetic cyclic dinucleotide (CDN) and agonist of stimulator of interferon genes protein (STING), with potential immunoactivating and antineoplastic activities. Upon intratumoral (IT) administration, STING agonist MK-1454 binds to STING and activates the STING pathway, which promotes IKK-related kinase TANK-binding kinase 1 (TBK1) signaling and activates nuclear factor-kappa B (NF-kB)...
Investigational
Matched Description: … kinase 1 (TBK1) signaling and activates nuclear factor-kappa B (NF-kB) and interferon regulatory factor 3 …

N-acetyl-beta-D-galactosamine 6-sulfate

Experimental

COVID-19 Spike-GM-CSF Protein Lactated Ringer's Injection

COVID-19 Spike-GM-CSF Protein Lactated Ringer's Injection is an intradermal injection currently being investigated in the clinical trial NCT03348670 (Discovery Stage (Proof-of-concept) COVID-19 Antigen Presentation Therapeutic Biologics (COVID-19--AP) (AP-TP-Bio)) .
Investigational

Ruscogenin

Experimental
Matched Iupac: … (1'S,2R,2'S,4'S,5R,7'S,8'R,9'S,12'S,13'R,14'R,16'R)-5,7',9',13'-tetramethyl-5'-oxaspiro[oxane-2,6'-pentacyclo …
Displaying drugs 8976 - 9000 of 12147 in total