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Displaying drugs 9001 - 9025 of 10976 in total

Recombinant SARS-CoV-2 Vaccine (Sf9 Cell)

The Recombinant SARS-CoV-2 Vaccine was created by inserting genes of the SARS-CoV-2 spike protein’s receptor-binding domain into a baculovirus expression system[F4738, A226853]. In pre-clinical trial testing on mice, rabbits, and non-human primates, the candidate was able to induce a functional antibody response within 7-14 days of initial injection . It...
Investigational
Matched Name: … Recombinant SARS-CoV-2 Vaccine (Sf9 Cell) …
Matched Description: … The Recombinant SARS-CoV-2 Vaccine was created by inserting genes of the SARS-CoV-2 spike protein’s receptor-binding ... It also provided protection in non-human primates to an in vivo challenge with SARS-CoV-2[A226853]. …

1-Hydroxyamine-2-Isobutylmalonic Acid

Experimental
Matched Name: … 1-Hydroxyamine-2-Isobutylmalonic Acid …
Matched Iupac: … (2R)-2-(hydroxycarbamoyl)-4-methylpentanoic acid …

S-(2-Acetamidoethyl) hexadecanethioate

Experimental
Matched Name: … S-(2-Acetamidoethyl) hexadecanethioate …
Matched Iupac: … N-[2-(hexadecanoylsulfanyl)ethyl]acetamide …

2',6'-DIFLUOROBIPHENYL-4-CARBOXYLIC ACID

Experimental
Matched Name: … 2',6'-DIFLUOROBIPHENYL-4-CARBOXYLIC ACID …
Matched Iupac: … 2',6'-difluoro-[1,1'-biphenyl]-4-carboxylic acid …

Captodiame

Captodiame, also known as captodiamine, is an antihistamine which is used as a sedative and anxiolytic. It is a derivative of diphenhydramine. Captodiame has been suggested for use in preventing benzodiazepine withdrawal syndrome.
Experimental
Matched Synonyms: … 2-[(4-butylsulfanylphenyl)-phenyl-methyl]sulfanyl-N,N-dimethylethanamine …
Matched Iupac: … [2-({[4-(butylsulfanyl)phenyl](phenyl)methyl}sulfanyl)ethyl]dimethylamine …
Matched Categories: … Serotonin 5-HT2 Receptor Antagonists ... Serotonin 5-HT2C Receptor Antagonists …

4-PHENOXY-N-(PYRIDIN-2-YLMETHYL)BENZAMIDE

Experimental
Matched Name: … 4-PHENOXY-N-(PYRIDIN-2-YLMETHYL)BENZAMIDE …
Matched Iupac: … 4-phenoxy-N-[(pyridin-2-yl)methyl]benzamide …

N-oxo-2-(phenylsulfonylamino)ethanamide

Experimental
Matched Name: … N-oxo-2-(phenylsulfonylamino)ethanamide …
Matched Iupac: … 2-benzenesulfonamido-N-oxoacetamide …

N-hydroxy-4-({4-[4-(trifluoromethyl)phenoxy]phenyl}sulfonyl)tetrahydro-2H-pyran-4-carboxamide

N-hydroxy-4-({4-[4-(trifluoromethyl)phenoxy]phenyl}sulfonyl)tetrahydro-2H-pyran-4-carboxamide is a solid. This compound belongs to the diarylethers. These are organic compounds containing the dialkyl ether functional group, with the formula ROR', where R and R' are aryl groups. This substance is known to target a disintegrin and metalloproteinase with thrombospondin motifs 5.
Experimental
Matched Description: … This substance is known to target a disintegrin and metalloproteinase with thrombospondin motifs 5. …

L-erythro-7,8-dihydrobiopterin

7,8-Dihydrobiopterin is an inhibitor of the enzyme dihydroneopterin aldolase (DHNA), which catalyzes the conversion of 7,8-Dihydrobiopterin to 6-hydroxymethyl-7,8-dihydropterin and glycolaldehyde.
Experimental
Matched Iupac: … 2-amino-6-[(1R,2S)-1,2-dihydroxypropyl]-1,4,7,8-tetrahydropteridin-4-one …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Allogenic Donor CD362-enriched Human Umbilical Cord-derived Mesenchymal Stem Cells

ORBCEL-C™ is the trade name of a product composed of highly purified stromal cells derived from the human umbilical cord. The isolated cells are expanded in culture and are able to be used allogenically -- meaning that one donor’s cells can be given to other unrelated patients. These cells are...
Investigational
Matched Description: … Regarding the modifications of these UC-MSCs, CD362, also known as syndecan-2, is a surface marker identified …

Pacanalotamab

Investigational

WRR-112

Experimental
Matched Iupac: … (3S)-3-hydroxy-3-{[(1S)-1-[(3-methylbutyl)carbamoyl]-3-phenylpropyl]carbamoyl}propanoic acid …

Galegenimab

Galegenimab is under investigation in clinical trial NCT03972709 (A Study Assessing the Safety, Tolerability, and Efficacy of Galegenimab (FHTR2163) in Participants With Geographic Atrophy Secondary to Age-related Macular Degeneration (AMD)).
Investigational

Batoclimab

Batoclimab is under investigation in clinical trial NCT04428255 (A Clinical Study on the Efficacy and Safety of HBM9161 in Patients With ITP).
Investigational

Domvanalimab

Domvanalimab is under investigation in clinical trial NCT05502237 (Zimberelimab and Domvanalimab in Combination With Chemotherapy Versus Pembrolizumab With Chemotherapy in Patients With Untreated Metastatic Non-small Cell Lung Cancer).
Investigational

2-[1-(4-CHLORO-PHENYL)-ETHYL]-4,6-DINITRO-PHENOL

Experimental
Matched Name: … 2-[1-(4-CHLORO-PHENYL)-ETHYL]-4,6-DINITRO-PHENOL …
Matched Iupac: … 2-[(1R)-1-(4-chlorophenyl)ethyl]-4,6-dinitrophenol …

N-Pyridoxyl-1-Amino-Cyclopropanecarboxylic Acid-5-Monophosphate

Experimental
Matched Name: … N-Pyridoxyl-1-Amino-Cyclopropanecarboxylic Acid-5-Monophosphate …
Matched Iupac: … 1-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)amino]cyclopropane-1-carboxylic acid …

PMP-hydroxyisoxazole, pyridoxamine-5-phosphate-hydroxyisoxazole

Experimental
Matched Name: … PMP-hydroxyisoxazole, pyridoxamine-5-phosphate-hydroxyisoxazole …
Matched Iupac: … [(5-hydroxy-6-methyl-4-{[(3-oxo-2,3-dihydro-1,2-oxazol-4-yl)amino]methyl}pyridin-3-yl)methoxy]phosphonic …

1,2-Dipalmitoyl-Phosphatidyl-Glycerole

Experimental

2-(Thiomethylene)-4-Methylpentanoic Acid

Experimental
Matched Name: … 2-(Thiomethylene)-4-Methylpentanoic Acid …
Matched Iupac: … (2S)-4-methyl-2-(sulfanylmethyl)pentanoic acid …

4-Iodobenzo[B]Thiophene-2-Carboxamidine

Experimental
Matched Name: … 4-Iodobenzo[B]Thiophene-2-Carboxamidine …
Matched Iupac: … [amino(4-iodo-1-benzothiophen-2-yl)methylidene]azanium …

alpha-N-Acetyl-D-galactosamine

The N-acetyl derivative of galactosamine. [PubChem]
Experimental
Investigational
Matched Synonyms: … N-acetyl-2-deoxy-2-amino-galactose …
Matched Iupac: … N-[(2S,3R,4R,5R,6R)-2,4,5-trihydroxy-6-(hydroxymethyl)oxan-3-yl]acetamide …

Zinpentraxin alfa

Zinpentraxin alfa is a recombinant form of PTX-2, a naturally circulating human protein. It is under investigation in clinical trial NCT01981850 (A Phase 2 Study Of PRM-151 In Subjects With Myelofibrosis).
Investigational
Matched Synonyms: … rhPTX-2 ... Recombinant human pentraxin-2 …
Matched Description: … Zinpentraxin alfa is a recombinant form of PTX-2, a naturally circulating human protein. ... It is under investigation in clinical trial NCT01981850 (A Phase 2 Study Of PRM-151 In Subjects With …

Ontamalimab

Ontamalimab is under investigation in clinical trial NCT03627091 (Efficacy and Safety Study of SHP647 as Maintenance Treatment in Participants With Moderate to Severe Crohn's Disease (CARMEN CD 307)).
Investigational

NGN-401

NGN-401 is a recombinant serotype 9 adeno-associated virus (AAV) encoding an intron encoding a miRNA generating sequence, complementary miRNA binding sites and a full-length human methyl cytosine binding protein 2 (MECP2). Developed by Neurogene Inc., it is being investigated for the treatment of Rett syndrome.
Investigational
Matched Synonyms: … sequence, complementary miRNA binding sites and a full-length human methyl cytosine binding protein 2 …
Matched Description: … sequence, complementary miRNA binding sites and a full-length human methyl cytosine binding protein 2 …
Displaying drugs 9001 - 9025 of 10976 in total