Displaying drugs 9051 - 9075 of 9822 in total
Adenosine disphosphate
Investigational
Matched Iupac: … [({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy] …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
AL5424
Experimental
Matched Iupac: … (4R)-4-hydroxy-2-(4-methoxyphenyl)-1,1-dioxo-2H,3H,4H-1lambda6-thieno[3,2-e][1,2]thiazine-6-sulfonamide …
AL7089A
Experimental
Matched Iupac: … (4R)-2-(3-methoxyphenyl)-4-(methylamino)-1,1-dioxo-2H,3H,4H-1lambda6-thieno[3,2-e][1,2]thiazine-6-sulfonamide …
Adenosine-5'-(Dithio)Phosphate
Experimental
Matched Iupac: … {[(2R,3S,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)sulfanyl-lambda5-phosphanethione …
AL7099A
Experimental
Matched Iupac: … (4S)-2-(3-methoxyphenyl)-4-(methylamino)-1,1-dioxo-2H,3H,4H-1lambda6-thieno[3,2-e][1,2]thiazine-6-sulfonamide …
Compound 4-D
Experimental
Matched Iupac: … (2S,3R)-3-(4-hydroxyphenyl)-2-{4-[2-(piperidin-1-yl)ethoxy]phenyl}-2,3-dihydro-1,4-benzoxathiin-6-ol …
Cediranib
The novel indole-ether quinazoline Cediranib is a highly potent (IC50 < 1 nmol/L) ATP-competitive inhibitor of recombinant KDR tyrosine kinase in vitro. It is being developed clinically as a once-daily oral therapy for the treatment of cancer.
Investigational
Matched Iupac: … 4-[(4-fluoro-2-methyl-1H-indol-5-yl)oxy]-6-methoxy-7-[3-(pyrrolidin-1-yl)propoxy]quinazoline …
Matched Salts cas: … 857036-77-2 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Salts cas: … 857036-77-2 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Canertinib
Canertinib is a pan-erbB tyrosine kinase inhibitor which work against esophageal squamous cell carcinoma in vitro and in vivo. Canertinib treatment significantly affects tumour metabolism, proliferation and hypoxia as determined by PET.
Investigational
Matched Iupac: … N-{4-[(3-chloro-4-fluorophenyl)amino]-7-[3-(morpholin-4-yl)propoxy]quinazolin-6-yl}prop-2-enamide …
Matched Salts cas: … 289499-45-2 …
Matched Salts cas: … 289499-45-2 …
LY-517717
LY517717 is an investigational oral direct inhibitor of activated Factor Xa. It is believed to be Lilly's PMD-3112 (licensed from Amgen).
Investigational
Matched Iupac: … N-[(1R)-2-[4-(1-methylpiperidin-4-yl)piperazin-1-yl]-2-oxo-1-phenylethyl]-1H-indole-6-carboxamide …
Torcetrapib
Torcetrapib (CP-529414, Pfizer) was developed to treat hypercholesterolemia but its development was halted in 2006 when phase III studies showed excessive mortality in the treatment group receiving a combination of atorvastatin and the study drug.
Investigational
Matched Iupac: … ethyl (2R,4S)-4-({[3,5-bis(trifluoromethyl)phenyl]methyl}(methoxycarbonyl)amino)-2-ethyl-6-(trifluoromethyl …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Pictilisib
Pictilisib has been used in trials studying the treatment of Solid Cancers, Breast Cancer, Advanced Solid Tumours, Metastatic Breast Cancer, and Non-Hodgkin's Lymphoma, Solid Cancers, among others.
Investigational
Matched Iupac: … 4-{6-[(4-methanesulfonylpiperazin-1-yl)methyl]-4-(morpholin-4-yl)thieno[3,2-d]pyrimidin-2-yl}-1H-indazole …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Phosphatidylinositol 3-Kinases, antagonists & inhibitors …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Phosphatidylinositol 3-Kinases, antagonists & inhibitors …
Voxtalisib
Voxtalisib has been used in trials studying the treatment of Cancer, Melanoma, Lymphoma, Glioblastoma, and Breast Cancer, among others.
Investigational
Matched Iupac: … 2-amino-8-ethyl-4-methyl-6-(1H-pyrazol-5-yl)-7H,8H-pyrido[2,3-d]pyrimidin-7-one …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Phosphatidylinositol 3-Kinases, antagonists & inhibitors …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Phosphatidylinositol 3-Kinases, antagonists & inhibitors …
RO-5028442
RO5028442 has been used in trials studying Autistic Disorder.
Investigational
Matched Iupac: … {2-[6-chloro-3-({3H-spiro[2-benzofuran-1,4'-piperidine]-1'-yl}carbonyl)-1H-indol-1-yl]ethyl}dimethylamine …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Methylestrenolone
Experimental
Matched Iupac: … (1S,2R,10R,11S,14S,15S)-14-hydroxy-14,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-6-en-5-one …
Ranimustine
Experimental
Matched Iupac: … 3-(2-chloroethyl)-3-nitroso-1-{[(2R,3S,4S,5R,6S)-3,4,5-trihydroxy-6-methoxyoxan-2-yl]methyl}urea …
LGH-447
LGH-447 is under investigation in clinical trial NCT02160951 (Dose Escalation Study of LGH447 in Japanese Patients With Relapsed and/or Refractory Hematologic Malignancies).
Investigational
Matched Iupac: … N-{4-[(1R,3S,5S)-3-amino-5-methylcyclohexyl]pyridin-3-yl}-6-(2,6-difluorophenyl)-5-fluoropyridine-2-carboxamide …
Fisogatinib
Fisogatinib is under investigation in clinical trial NCT04194801 (A Phase Ib/ii Study of Fisogatinib(blu-554) in Subjects With Hepatocellular Carcinoma).
Investigational
Matched Iupac: … N-[(3S,4S)-3-{[6-(2,6-dichloro-3,5-dimethoxyphenyl)quinazolin-2-yl]amino}oxan-4-yl]prop-2-enamide …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Nedisertib
Nedisertib is under investigation in clinical trial NCT03770689 (Study of M3814 in Combination With Capecitabine and Radiotherapy in Rectal Cancer).
Investigational
Matched Iupac: … (S)-{2-chloro-4-fluoro-5-[7-(morpholin-4-yl)quinazolin-4-yl]phenyl}(6-methoxypyridazin-3-yl)methanol …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Raceanisodamine
Investigational
Matched Iupac: … (1R,3S,5R,6S)-6-hydroxy-8-methyl-8-azabicyclo[3.2.1]octan-3-yl (2S)-3-hydroxy-2-phenylpropanoate …
Madecassoside
Experimental
Matched Iupac: … -6-methyloxan-2-yl]oxy}oxan-2-yl]oxy}methyl)-3,4,5-trihydroxyoxan-2-yl (1S,2R,4aS,6aS,6bR,8R,8aR,9R,10R ... (2S,3R,4S,5S,6R)-6-({[(2R,3R,4R,5S,6R)-3,4-dihydroxy-6-(hydroxymethyl)-5-{[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy …
CMG901
CMG901 is an anti-Claudin 18.2 monoclonal antibody conjugated with MMAE payload.
Investigational
5,8-dimethoxy-1,4-dimethylquinolin-2(1H)-one
Experimental
Matched Name: … 5,8-dimethoxy-1,4-dimethylquinolin-2(1H)-one …
Matched Iupac: … 5,8-dimethoxy-1,4-dimethyl-1,2-dihydroquinolin-2-one …
Matched Iupac: … 5,8-dimethoxy-1,4-dimethyl-1,2-dihydroquinolin-2-one …
10-formyl-5,8,10-trideazafolic acid
Experimental
Matched Iupac: … (2S)-2-({4-[(1S)-2-(2-amino-4-oxo-1,4-dihydroquinazolin-6-yl)-1-carboxyethyl]phenyl}formamido)pentanedioic …
(R)-minalrestat
Experimental
Matched Iupac: … (4R)-2-[(4-bromo-2-fluorophenyl)methyl]-6-fluoro-2,3-dihydro-1H-spiro[isoquinoline-4,3'-pyrrolidine]- …
Luseogliflozin
Luseogliflozin has been used in trials studying the treatment of Diabetes Melltius, Type 2.
Investigational
Matched Iupac: … (2S,3R,4R,5S,6R)-2-{5-[(4-ethoxyphenyl)methyl]-2-methoxy-4-methylphenyl}-6-(hydroxymethyl)thiane-3,4,5 …
Matched Description: … Luseogliflozin has been used in trials studying the treatment of Diabetes Melltius, Type 2. …
Matched Categories: … Sodium-glucose Cotransporter 2 (SGLT2) Inhibitors …
Matched Description: … Luseogliflozin has been used in trials studying the treatment of Diabetes Melltius, Type 2. …
Matched Categories: … Sodium-glucose Cotransporter 2 (SGLT2) Inhibitors …
Displaying drugs 9051 - 9075 of 9822 in total