Displaying drugs 901 - 925 of 1258 in total
Ohmefentanyl
Ohmefentanyl is an extremely potent opioid analgesic drug which selectively binds to the µ-opioid receptor. The Chinese have recorded ohmefentanyl as having a potency that is 6,300 times morphine. Ohmefentanyl is one of the most potent μ -receptor agonists known, comparable to super-potent opioids such as carfentanil and etorphine which...
Illicit
Matched Synonyms: … Beta-hydroxy-3-methylfentanyl …
Matched Description: … the most potent μ -receptor agonists known, comparable to super-potent opioids such as carfentanil and ... In mice, ohmefentanyl was 28 times more powerful than fentanyl and 6300 times more effective than morphine ... Ohmefentanyl has three stereogenic centers and hence, it can derive into eight stereoisomers, currently …
Matched Description: … the most potent μ -receptor agonists known, comparable to super-potent opioids such as carfentanil and ... In mice, ohmefentanyl was 28 times more powerful than fentanyl and 6300 times more effective than morphine ... Ohmefentanyl has three stereogenic centers and hence, it can derive into eight stereoisomers, currently …
Vestronidase alfa
Vestronidase alfa, or vestronidase alfa-vjbk, is a recombinant human lysosomal beta glucuronidase that is a purified enzyme produced by recombinant DNA technology in a Chinese hamster ovary cell line. The enzyme is a homotetramer consisted of 4 monomers with 629 amino acids, and holds the same amino acid sequence as...
Approved
Investigational
Matched Synonyms: … Recombinant human beta-glucuronidase …
Matched Description: … and patients may experience developmental delay and progressive intellectual disability [FDA Label]. ... known as Sly syndrome, which is an inherited, rare genetic metabolic condition that targets a small subset ... spleen, heart valve abnormalities, and narrowed airways which can lead to lung infections and trouble …
Matched Categories: … Alimentary Tract and Metabolism ... Enzymes and Coenzymes ... Lysosomal beta Glucuronidase …
Matched Description: … and patients may experience developmental delay and progressive intellectual disability [FDA Label]. ... known as Sly syndrome, which is an inherited, rare genetic metabolic condition that targets a small subset ... spleen, heart valve abnormalities, and narrowed airways which can lead to lung infections and trouble …
Matched Categories: … Alimentary Tract and Metabolism ... Enzymes and Coenzymes ... Lysosomal beta Glucuronidase …
Ribaxamase
Ribaxamase is under investigation in clinical trial NCT02563106 (A Study of SYN-004 for the Prevention of c.diff in Patients With a LRTI).
Investigational
Matched Synonyms: … .beta.-lactamase (synthetic bacillus licheniformis isoenzyme syn-004) …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes …
Nicotinyl alcohol
A direct-acting peripheral vasodilator that causes flushing and may decrease blood pressure. It is used in vasospasm and threatened gangrene. [PubChem]
Experimental
Matched Synonyms: … beta-pyridylcarbinol …
Matched Description: … A direct-acting peripheral vasodilator that causes flushing and may decrease blood pressure. ... It is used in vasospasm and threatened gangrene. [PubChem] …
Matched Categories: … Nicotinic Acid and Derivatives …
Matched Description: … A direct-acting peripheral vasodilator that causes flushing and may decrease blood pressure. ... It is used in vasospasm and threatened gangrene. [PubChem] …
Matched Categories: … Nicotinic Acid and Derivatives …
Clevudine
Investigational
Matched Synonyms: … 2'-Fluoro-5-methyl-beta-L-arabinofuranosyluracil …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides ... Nucleoside and Nucleotide Reverse Transcriptase Inhibitors …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides ... Nucleoside and Nucleotide Reverse Transcriptase Inhibitors …
S-(N-hydroxy-N-bromophenylcarbamoyl)glutathione
Experimental
Matched Synonyms: … (2S)-2-Amino-5-[[(2R)-3-[(S)-(4-bromo-N-hydroxyanilino)-hydroxymethyl]sulfanyl-1-(carboxymethylamino) …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Aspacytarabine
Investigational
Matched Synonyms: … L-asparagine, n-(1-.beta.-d-arabinofuranosyl-1,2-dihydro-2-oxo-4-pyrimidinyl)- ... N4-(1-.beta.-d-arabinofuranosyl-2-oxo-1,2-dihydropyrimidin-4-yl)-l-asparagine …
Duloxetine
Duloxetine is a dual serotonin and norepinephrine reuptake inhibitor.[label] It was originally discovered in 1993 and developed by Eli Lilly and Company as LY248686. Duloxetine first received approval from the FDA in August, 2004 as Cymbalta for the treatment of Major Depressive Disorder. It has since received approval for a...
Approved
Matched Description: … [label] It was originally discovered in 1993 and developed by Eli Lilly and Company as LY248686. ... Duloxetine is a dual serotonin and norepinephrine reuptake inhibitor. ... Duloxetine continues to be investigated for the treatment of pain in cancer, surgery, and more. …
Matched Categories: … Serotonin and Noradrenaline Reuptake Inhibitors …
Matched Products: … DULOXETIN BETA 30MG ... DULOXETIN BETA 45MG ... DULOXETIN BETA 60MG …
Matched Categories: … Serotonin and Noradrenaline Reuptake Inhibitors …
Matched Products: … DULOXETIN BETA 30MG ... DULOXETIN BETA 45MG ... DULOXETIN BETA 60MG …
Propiolactone
Propiolactone is a lactone compound with a four-membered ring. It is a colorless liquid with a pungent slightly sweet odor. Propiolactone is a disinfectant used for the sterilization of blood plasma, vaccines, tissue grafts, surgical instruments, and enzymes. It has been used against bacteria, fungi, and virus. It is currently...
Approved
Withdrawn
Matched Synonyms: … beta-Propiolactone …
Matched Description: … It has been used against bacteria, fungi, and virus. ... disinfectant used for the sterilization of blood plasma, vaccines, tissue grafts, surgical instruments, and …
Matched Description: … It has been used against bacteria, fungi, and virus. ... disinfectant used for the sterilization of blood plasma, vaccines, tissue grafts, surgical instruments, and …
Isoquercitrin
Isoquercitrin is under investigation in clinical trial NCT04622865 (Masitinib Combined With Isoquercetin and Best Supportive Care in Hospitalized Patients With Moderate and Severe COVID-19).
Investigational
Matched Synonyms: … Quercetin 3-(beta-D-glucofuranoside) …
Matched Description: … Isoquercitrin is under investigation in clinical trial NCT04622865 (Masitinib Combined With Isoquercetin and ... Best Supportive Care in Hospitalized Patients With Moderate and Severe COVID-19). …
Matched Description: … Isoquercitrin is under investigation in clinical trial NCT04622865 (Masitinib Combined With Isoquercetin and ... Best Supportive Care in Hospitalized Patients With Moderate and Severe COVID-19). …
Fusidic acid
An antibiotic isolated from the fermentation broth of Fusidium coccineum. (From Merck Index, 11th ed) It acts by inhibiting translocation during protein synthesis. It is often used topically in creams and eyedrops but is available in systemic formulations including tablets and injections.
Approved
Investigational
Matched Description: … tablets and injections. ... It is often used topically in creams and eyedrops but is available in systemic formulations including …
Matched Mixtures name: … BACTAFUZ-B Fusidic Acid and Betamethasone Valerate Cream ... ACELER-CO …
Matched Products: … ACELER …
Matched Mixtures name: … BACTAFUZ-B Fusidic Acid and Betamethasone Valerate Cream ... ACELER-CO …
Matched Products: … ACELER …
(S)-4-bromo-3-hydroxy-3-methylbutyl diphosphate
Experimental
Matched Name: … (S)-4-bromo-3-hydroxy-3-methylbutyl diphosphate …
Matched Iupac: … ({[(3S)-4-bromo-3-hydroxy-3-methylbutoxy](hydroxy)phosphoryl}oxy)phosphonic acid …
Matched Iupac: … ({[(3S)-4-bromo-3-hydroxy-3-methylbutoxy](hydroxy)phosphoryl}oxy)phosphonic acid …
Riluzole
A glutamate antagonist (receptors, glutamate) used as an anticonvulsant (anticonvulsants) and to prolong the survival of patients with amyotrophic lateral sclerosis. Riluzole is marketed as Rilutek by Sanofi.
Approved
Investigational
Matched Description: … A glutamate antagonist (receptors, glutamate) used as an anticonvulsant (anticonvulsants) and to prolong …
Matched Products: … RILUZOL BETA 50MG …
Matched Products: … RILUZOL BETA 50MG …
4-BROMO-3-(CARBOXYMETHOXY)-5-PHENYLTHIOPHENE-2-CARBOXYLIC ACID
Experimental
Matched Name: … 4-BROMO-3-(CARBOXYMETHOXY)-5-PHENYLTHIOPHENE-2-CARBOXYLIC ACID …
Matched Iupac: … 4-bromo-3-(carboxymethoxy)-5-phenylthiophene-2-carboxylic acid …
Matched Iupac: … 4-bromo-3-(carboxymethoxy)-5-phenylthiophene-2-carboxylic acid …
Febuxostat
Febuxostat is a non-purine xanthine oxidase (XO) inhibitor. In early 2008, febuxostat was granted marketing authorization by the European Commission for the treatment of chronic hyperuricemia and gout. In the following year, the FDA for approved febuxostat for use in the chronic management of hyperuricemia in adult patients with gout...
Approved
Matched Description: … Febuxostat is a non-purine xanthine oxidase (XO) inhibitor. ... granted marketing authorization by the European Commission for the treatment of chronic hyperuricemia and ... that is caused by the accumulation of uric acid crystal in or around a joint, leading to inflammation and …
Matched Categories: … Xanthine Oxidase Inhibitors …
Matched Products: … FEBUXOSTAT BETA 80MG FTA ... FEBUXOSTAT BETA 120MG FTA …
Matched Categories: … Xanthine Oxidase Inhibitors …
Matched Products: … FEBUXOSTAT BETA 80MG FTA ... FEBUXOSTAT BETA 120MG FTA …
2-Fluoro-2-Deoxy-Beta-D-Galactopyranosyl-Beta-D-Glucopyranose
Experimental
Matched Name: … 2-Fluoro-2-Deoxy-Beta-D-Galactopyranosyl-Beta-D-Glucopyranose …
Gabapentin
Gabapentin is a structural analogue of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA) that was first approved for use in the United States in 1993. It was originally developed as a novel anti-epileptic for the treatment of certain types of seizures[A186277,A186143] - today it is also widely used to treat neuropathic...
Approved
Investigational
Matched Description: … It is structurally and functionally related to another GABA derivative, [pregabalin]. ... other anti-epileptics, such as a relatively benign adverse effect profile, wide therapeutic index, and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Gabapentin and Prodrugs …
Matched Products: … GABAPENTIN BETA 100MG ... GABAPENTIN BETA 300MG ... GABAPENTIN BETA 400MG …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Gabapentin and Prodrugs …
Matched Products: … GABAPENTIN BETA 100MG ... GABAPENTIN BETA 300MG ... GABAPENTIN BETA 400MG …
Radgocitabine
2'-cyano-2'-deoxy-1-(beta-D-arabinofuranosyl)cytosine has been used in trials studying the treatment of Advanced Colorectal Cancer.
Investigational
Matched Synonyms: … 2'-cyano-2'-deoxy-1-(beta-D-arabinofuranosyl)cytosine …
Matched Description: … 2'-cyano-2'-deoxy-1-(beta-D-arabinofuranosyl)cytosine has been used in trials studying the treatment …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Matched Description: … 2'-cyano-2'-deoxy-1-(beta-D-arabinofuranosyl)cytosine has been used in trials studying the treatment …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
4-(5-Bromo-2-Oxo-2h-Indol-3-Ylazo)-Benzenesulfonamide
Experimental
Matched Name: … 4-(5-Bromo-2-Oxo-2h-Indol-3-Ylazo)-Benzenesulfonamide …
Matched Iupac: … 4-[(1E)-2-(5-bromo-2-oxo-2H-indol-3-yl)diazen-1-yl]benzene-1-sulfonamide …
Matched Iupac: … 4-[(1E)-2-(5-bromo-2-oxo-2H-indol-3-yl)diazen-1-yl]benzene-1-sulfonamide …
3-bromo-N'-[(1E)-(3,5-dibromo-2,4-dihydroxyphenyl)methylidene]benzohydrazide
Experimental
Matched Name: … 3-bromo-N'-[(1E)-(3,5-dibromo-2,4-dihydroxyphenyl)methylidene]benzohydrazide …
Matched Iupac: … 3-bromo-N'-[(E)-(3,5-dibromo-2,4-dihydroxyphenyl)methylidene]benzohydrazide …
Matched Iupac: … 3-bromo-N'-[(E)-(3,5-dibromo-2,4-dihydroxyphenyl)methylidene]benzohydrazide …
Dideoxyadenosine
Investigational
Matched Synonyms: … 6-amino-9-(2',3'-dideoxy-.beta.-d-glycero-pentofuranosyl)purine ... 9-(2,3-dideoxy-.beta.-d-glycero-pentofuranosyl)-9h-purin-6-amine …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
4-(Hydrogen sulfate)-beta-D-galactopyranose
Experimental
Matched Synonyms: … 4-(Hydrogen sulfate)-beta-D-galactopyranose …
Matched Name: … 4-(Hydrogen sulfate)-beta-D-galactopyranose …
Matched Name: … 4-(Hydrogen sulfate)-beta-D-galactopyranose …
Displaying drugs 901 - 925 of 1258 in total