Displaying drugs 901 - 925 of 2908 in total
Insulin detemir
Insulin detemir is a long-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes.[A2358, A2359, A2360, A44] Insulin is typically prescribed for the management of diabetes mellitus to mimic the activity of endogenously produced human insulin, a peptide hormone produced by beta...
Approved
Matched Synonyms: … Insulin,detemir,human …
Matched Description: … amino acid at position B29. ... typically prescribed for the management of diabetes mellitus to mimic the activity of endogenously produced human ... [A2358, A2359, A2360, A44] This insulin analogue has a 14-C fatty acid, myristic acid, bound to the lysine …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Alimentary Tract and Metabolism ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Description: … amino acid at position B29. ... typically prescribed for the management of diabetes mellitus to mimic the activity of endogenously produced human ... [A2358, A2359, A2360, A44] This insulin analogue has a 14-C fatty acid, myristic acid, bound to the lysine …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Alimentary Tract and Metabolism ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Carlumab
Carlumab has been used in trials studying the treatment of Cancer and Prostate Cancer.
Investigational
Withdrawn
Matched Synonyms: … Human monoclonal antibody targeting CC-chemokine ligand 2 (CNTO 888) …
Matched Description: … Carlumab has been used in trials studying the treatment of Cancer and Prostate Cancer. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … Carlumab has been used in trials studying the treatment of Cancer and Prostate Cancer. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
HMI-103
HMI-102 is an investigational gene therapy designed to encode the phenylalanine-4-hydroxylase (PAH) gene, mutated in people with phenylketonuria.
Investigational
Matched Synonyms: … Recombinant adeno-associated viral vector serotype HSC expressing human phenylalanine hydroxylase …
Expanded human allogeneic neural retinal progenitor cells extracted from neural retina
Investigational
Matched Synonyms: … Expanded human allogeneic neural retinal progenitor cells extracted from neural retina …
Matched Name: … Expanded human allogeneic neural retinal progenitor cells extracted from neural retina …
Matched Name: … Expanded human allogeneic neural retinal progenitor cells extracted from neural retina …
Pemtumomab
Pemtumomab is a murine monoclonal antibody radiolabeled with Yttrium-90. It targets the mucin 1 (MUC1) protein.
Investigational
Matched Synonyms: … Murine MAb to polymorphic epithelial mucin, human milk fat globule 1 …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
BGT-DTDS
BGT-DTDS is an investigational gene therapy comprising an adeno-associated viral vector type 2 (AAV2) encoding the human SLC6A3 gene. It is under investigation for the treatment of dopamine transporter deficiency syndrome (DTDS).
Investigational
Matched Synonyms: … Adeno-associated viral vector serotype 2 containing the human SLC6A3 gene …
Matched Description: … investigational gene therapy comprising an adeno-associated viral vector type 2 (AAV2) encoding the human …
Matched Description: … investigational gene therapy comprising an adeno-associated viral vector type 2 (AAV2) encoding the human …
Phenolsulfonic acid
Experimental
Matched Synonyms: … Sulfocarbolic acid ... Phenolsulfonic acid ... p-Phenolsulfonic acid …
Matched Name: … Phenolsulfonic acid …
Matched Iupac: … 4-hydroxybenzene-1-sulfonic acid …
Matched Name: … Phenolsulfonic acid …
Matched Iupac: … 4-hydroxybenzene-1-sulfonic acid …
Teriparatide
Teriparatide is a recombinant parathyroid hormone (PTH) analog and a potent osteoanabolic agent. It is made up of the first amino(N)-terminal 34 amino acids of the human PTH. First approved in the United States in November 2002 and in Europe in April 2003, teriparatide makes the first approved drug in...
Approved
Investigational
Matched Synonyms: … Teriparatide recombinant human …
Matched Description: … [A251395] It is made up of the first amino(N)-terminal 34 amino acids of the human PTH. ... Teriparatide is a recombinant parathyroid hormone (PTH) analog and a potent osteoanabolic agent. ... [A251395] First approved in the United States in November 2002 and in Europe in April 2003,[A251400] …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Sex Hormones and Insulins ... Calcium-Regulating Hormones and Agents ... Parathyroid Hormones and Analogues ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Description: … [A251395] It is made up of the first amino(N)-terminal 34 amino acids of the human PTH. ... Teriparatide is a recombinant parathyroid hormone (PTH) analog and a potent osteoanabolic agent. ... [A251395] First approved in the United States in November 2002 and in Europe in April 2003,[A251400] …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Sex Hormones and Insulins ... Calcium-Regulating Hormones and Agents ... Parathyroid Hormones and Analogues ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Mirococept
Mirococept (APT070) is a complement inhibitor currently under development for treatment of rheumatoid arthritis and I/RI. It is a truncated form of the human Complement Receptor 1 (CR1) linked to a unique Prodaptin™ construct that regulates the over-production of complement at the cell surface, which occurs in inflammation. It consists...
Investigational
Matched Synonyms: … myristoylated recombinant SCR1-3 of human complement reseptor type I …
Matched Description: … APT070) is a complement inhibitor currently under development for treatment of rheumatoid arthritis and ... in recombinant bacteria and modified with a membrane-targeting amphiphilic peptide based on the naturally ... It is a truncated form of the human Complement Receptor 1 (CR1) linked to a unique Prodaptin™ construct …
Matched Description: … APT070) is a complement inhibitor currently under development for treatment of rheumatoid arthritis and ... in recombinant bacteria and modified with a membrane-targeting amphiphilic peptide based on the naturally ... It is a truncated form of the human Complement Receptor 1 (CR1) linked to a unique Prodaptin™ construct …
Eptacog alfa pegol (activated)
Eptacog alfa pegol (activated) has been used in trials studying the prevention and treatment of Haemophilia A, Haemophilia B, Congenital Bleeding Disorder, Haemophilia B With Inhibitors, and Haemophilia A With Inhibitors.
Investigational
Matched Synonyms: … Activated Recombinant Human Factor VII, Long Acting …
Matched Description: … Eptacog alfa pegol (activated) has been used in trials studying the prevention and treatment of Haemophilia ... A, Haemophilia B, Congenital Bleeding Disorder, Haemophilia B With Inhibitors, and Haemophilia A With …
Matched Description: … Eptacog alfa pegol (activated) has been used in trials studying the prevention and treatment of Haemophilia ... A, Haemophilia B, Congenital Bleeding Disorder, Haemophilia B With Inhibitors, and Haemophilia A With …
Velmanase alfa
Velmanase alfa is a recombinant human lysosomal alpha-mannosidase developed for enzyme replacement therapy to treat alpha-mannosidosis. Alpha-mannosidosis is a rare autosomal recessive lysosomal storage disorder. Patients with alpha-mannosidosis have a genetic mutation that causes a deficiency in the lysosomal enzyme alpha-mannosidase, which is an enzyme responsible for breaking down complex...
Approved
Investigational
Matched Synonyms: … Recombinant Human Alpha Mannosidase …
Matched Description: … sugars in the body leads to an array of clinical manifestations leading to progressive neuromuscular and ... deterioration, such as skeletal abnormalities, motor function impairment, intellectual disability, and ... human alpha-mannosidase. …
Matched Categories: … Enzymes and Coenzymes ... Alimentary Tract and Metabolism ... Recombinant Human Lysosomal alpha-Mannosidase …
Matched Description: … sugars in the body leads to an array of clinical manifestations leading to progressive neuromuscular and ... deterioration, such as skeletal abnormalities, motor function impairment, intellectual disability, and ... human alpha-mannosidase. …
Matched Categories: … Enzymes and Coenzymes ... Alimentary Tract and Metabolism ... Recombinant Human Lysosomal alpha-Mannosidase …
Vonicog alfa
Vonicog alfa is a recombinant von Willebrand factor manufactured by Baxalta. It was FDA approved in December 2015. The gen of von Willebrand factor was first cloned in 1985 by Stuart Orkin and David Ginsburg. By the EMA, vonicog alfa is still under clinical analysis.
Approved
Investigational
Matched Synonyms: … Von willebrand factor, recombinant, human …
Matched Description: … [A32230] The gen of von Willebrand factor was first cloned in 1985 by Stuart Orkin and David Ginsburg …
Matched Description: … [A32230] The gen of von Willebrand factor was first cloned in 1985 by Stuart Orkin and David Ginsburg …
Pegilodecakin
Pegilodecakin is under investigation in clinical trial NCT03382912 (Study of Pegilodecakin (LY3500518) With Nivolumab Compared to Nivolumab Alone Second-line Tx in Participants With Metastatic Non-Small Cell Lung Cancer).
Investigational
Matched Synonyms: … INTERLEUKIN 10 (SYNTHETIC HUMAN), DIMER, N-TERMINAL 5-KILODALTON PEGYLATED …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
RLYB212
RLYB212 is a human monoclonal antibody against Antigen-1A Immunoglobulin (HPA-1A). It is currently being developed by Rallybio for the prevention of fetal and neonatal alloimmune thrombocytopenia.
Investigational
Matched Synonyms: … Recombinant human IgG monoclonal HPA-1a antibody …
Matched Description: … It is currently being developed by Rallybio for the prevention of fetal and neonatal alloimmune thrombocytopenia ... RLYB212 is a human monoclonal antibody against Antigen-1A Immunoglobulin (HPA-1A). …
Matched Description: … It is currently being developed by Rallybio for the prevention of fetal and neonatal alloimmune thrombocytopenia ... RLYB212 is a human monoclonal antibody against Antigen-1A Immunoglobulin (HPA-1A). …
p-Coumaric acid
Experimental
Matched Synonyms: … 4-coumaric acid ... p-Coumaric acid ... (E)-p-coumaric acid …
Matched Name: … p-Coumaric acid …
Matched Iupac: … (2E)-3-(4-hydroxyphenyl)prop-2-enoic acid …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids …
Matched Name: … p-Coumaric acid …
Matched Iupac: … (2E)-3-(4-hydroxyphenyl)prop-2-enoic acid …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids …
MK-2225
Investigational
Matched Synonyms: … transforming growth factor beta receptor type II linked to a human IgG1 Fc domain ... Homodimeric fragment crystallizable fusion protein comprised of the extracellular domain of the human …
Temelimab
Temelimab is under investigation in clinical trial NCT02782858 (Clinical Trial Assessing the HERV-W Env Antagonist Gnbac1 for Efficacy in MS).
Investigational
Matched Synonyms: … Immunoglobulin G4, anti-(multiple sclerosis-associated retrovirus viral envelope protein) (human-mus ... musculus monoclonal gnbac1 heavy chain), disulfide with human-mus musculus monoclonal gnbac1 kappa-chain …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Vinylsulfonic acid
Experimental
Matched Synonyms: … Vinylsulphonic acid ... Ethylenesulfonic acid …
Matched Name: … Vinylsulfonic acid …
Matched Iupac: … ethenesulfonic acid …
Matched Categories: … Acids ... Sulfur Acids ... Acids, Noncarboxylic …
Matched Name: … Vinylsulfonic acid …
Matched Iupac: … ethenesulfonic acid …
Matched Categories: … Acids ... Sulfur Acids ... Acids, Noncarboxylic …
Oxogluric acid
Oxogluric acid (α-Ketoglutarate) is not approved for any indication in the world but is an investigational drug in the United States. In the United States a phase I clinical trial is investigating whether oxogluric acid precursors found in nutritional supplements can benefit patients with the metabolic disorder propionic acidemia. Oxogluric...
Experimental
Investigational
Nutraceutical
Matched Synonyms: … 2-Ketoglutaric acid ... 2-oxoglutaric acid ... Ketoglutaric acid …
Matched Name: … Oxogluric acid …
Matched Iupac: … 2-oxopentanedioic acid …
Matched Description: … reactions during the metabolism of amino acids, forms glutamic acid by combining with ammonia, and reduces ... remove excess ammonia, but it is not officially approved for this indication and only experimental studies ... have shown a reduction in ammonia by oxogluric acid in hemodialysis patients. …
Matched Categories: … Keto Acids ... Acids, Acyclic ... Carboxylic Acids ... Dicarboxylic Acids ... Ketoglutaric Acids …
Matched Name: … Oxogluric acid …
Matched Iupac: … 2-oxopentanedioic acid …
Matched Description: … reactions during the metabolism of amino acids, forms glutamic acid by combining with ammonia, and reduces ... remove excess ammonia, but it is not officially approved for this indication and only experimental studies ... have shown a reduction in ammonia by oxogluric acid in hemodialysis patients. …
Matched Categories: … Keto Acids ... Acids, Acyclic ... Carboxylic Acids ... Dicarboxylic Acids ... Ketoglutaric Acids …
Amoxicillin
Amoxicillin, or BRL-2333, is a penicillin G derivative first described in the literature in 1972. Amoxicillin has similar activity to penicillin and ampicillin, but leads to higher serum concentrations than ampicillin. Amoxicillin was granted FDA approval on 18 January 1974.
Approved
Vet approved
Matched Synonyms: … 6-(p-hydroxy-α-aminophenylacetamido)penicillanic acid ... -2-(4-hydroxyphenyl)acetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid …
Matched Iupac: … amino-2-(4-hydroxyphenyl)acetamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid …
Matched Description: … [A190648] Amoxicillin has similar activity to [penicillin] and [ampicillin], but leads to higher serum …
Matched Mixtures name: … Clavulin 125 F Oral Sus ... Clavulin 250 F Oral Sus ... Amoxicillin/Clav Pot Oral Susp …
Matched Categories: … Drugs for Acid Related Disorders ... Alimentary Tract and Metabolism ... vonoprazan and amoxicillin ... omeprazole, amoxicillin and rifabutin ... vonoprazan, amoxicillin and clarithromycin …
Matched Products: … AMOXICILLINA E ACIDO CLAVULANICO PFIZER ... Nu-amoxi Sus 125/5ml ... Nu-amoxi Sus 250mg/5ml …
Matched Iupac: … amino-2-(4-hydroxyphenyl)acetamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid …
Matched Description: … [A190648] Amoxicillin has similar activity to [penicillin] and [ampicillin], but leads to higher serum …
Matched Mixtures name: … Clavulin 125 F Oral Sus ... Clavulin 250 F Oral Sus ... Amoxicillin/Clav Pot Oral Susp …
Matched Categories: … Drugs for Acid Related Disorders ... Alimentary Tract and Metabolism ... vonoprazan and amoxicillin ... omeprazole, amoxicillin and rifabutin ... vonoprazan, amoxicillin and clarithromycin …
Matched Products: … AMOXICILLINA E ACIDO CLAVULANICO PFIZER ... Nu-amoxi Sus 125/5ml ... Nu-amoxi Sus 250mg/5ml …
Dinutuximab
Dinutuximab is an IgG1 monoclonal human/mouse chimeric antibody against GD2, a disialoganglioside expressed on tumors of neuroectodermal origin, including human neuroblastoma and melanoma, with highly restricted expression on normal tissues. It is composed of the variable heavy- and light-chain regions of the murine anti-GD2 mAb 14.18 and the constant regions...
Approved
Investigational
Matched Synonyms: … WITH HUMAN-MUS MUSCULUS MONOCLONAL CH14.18 LIGHT CHAIN, DIMER ... WITH HUMAN-MUS MUSCULUS MONOCLONAL CH14.18/CHO LIGHT CHAIN, DIMER ... IMMUNOGLOBULIN G1, ANTI-(GANGLIOSIDE GD2) (HUMAN-MUS MUSCULUS MONOCLONAL CH14.18 HEAVY CHAIN), DISULFIDE …
Matched Description: … constant regions of human IgG1 heavy-chain and kappa light-chain. ... on tumors of neuroectodermal origin, including human neuroblastoma and melanoma, with highly restricted ... 13-cis-retinoic acid (RA), for the treatment of pediatric patients with high-risk neuroblastoma who …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Matched Description: … constant regions of human IgG1 heavy-chain and kappa light-chain. ... on tumors of neuroectodermal origin, including human neuroblastoma and melanoma, with highly restricted ... 13-cis-retinoic acid (RA), for the treatment of pediatric patients with high-risk neuroblastoma who …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
2,2-Dimethylbutyrate
Investigational
Matched Synonyms: … Dimebutic acid ... 2,2-dimethylbutanoic acid ... 2,2-dimethylbutyric acid …
Matched Iupac: … 2,2-dimethylbutanoic acid …
Matched Categories: … Fatty Acids ... Acids, Acyclic ... Carboxylic Acids ... Fatty Acids, Volatile …
Matched Iupac: … 2,2-dimethylbutanoic acid …
Matched Categories: … Fatty Acids ... Acids, Acyclic ... Carboxylic Acids ... Fatty Acids, Volatile …
(R)-Mandelic acid
Experimental
Matched Synonyms: … (−)-mandelic acid ... (−)-(R)-mandelic acid ... D-mandelic acid …
Matched Name: … (R)-Mandelic acid …
Matched Iupac: … (2R)-2-hydroxy-2-phenylacetic acid …
Matched Name: … (R)-Mandelic acid …
Matched Iupac: … (2R)-2-hydroxy-2-phenylacetic acid …
Thiosalicylic acid
Experimental
Matched Synonyms: … 2-Thiosalicylic acid ... 2-Mercaptobenzoic acid ... o-Benzoic acid thiol …
Matched Name: … Thiosalicylic acid …
Matched Iupac: … 2-sulfanylbenzoic acid …
Matched Categories: … Acids, Carbocyclic ... Hydroxy Acids ... Carboxylic Acids …
Matched Name: … Thiosalicylic acid …
Matched Iupac: … 2-sulfanylbenzoic acid …
Matched Categories: … Acids, Carbocyclic ... Hydroxy Acids ... Carboxylic Acids …
Citraconic acid
Citraconic acid is one of the isomeric dicarboxylic acids produced by the distillation of citric acid, or as metabolites by microorganisms, cis-CH3-C(CO2H)=CHCO2H; the trans-isomer is mesaconic acid.
Experimental
Matched Synonyms: … 2-methylmaleic acid ... Methylmaleic acid ... α-methylmaleic acid …
Matched Name: … Citraconic acid …
Matched Iupac: … (2Z)-2-methylbut-2-enedioic acid …
Matched Description: … Citraconic acid is one of the isomeric dicarboxylic acids produced by the distillation of citric acid ... , or as metabolites by microorganisms, cis-CH3-C(CO2H)=CHCO2H; the trans-isomer is mesaconic acid. …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids ... Dicarboxylic Acids …
Matched Name: … Citraconic acid …
Matched Iupac: … (2Z)-2-methylbut-2-enedioic acid …
Matched Description: … Citraconic acid is one of the isomeric dicarboxylic acids produced by the distillation of citric acid ... , or as metabolites by microorganisms, cis-CH3-C(CO2H)=CHCO2H; the trans-isomer is mesaconic acid. …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids ... Dicarboxylic Acids …
Displaying drugs 901 - 925 of 2908 in total