Advanced Filter

Filter by Group

Filter by Market Availability

Clear
Displaying drugs 901 - 925 of 5411 in total

Leflunomide

Leflunomide is a pyrimidine synthesis inhibitor belonging to the DMARD (disease-modifying antirheumatic drug) class of drugs, which are chemically and pharmacologically very heterogeneous. Leflunomide was approved by FDA and in many other countries (e.g., Canada, Europe) in 1999.
Approved
Investigational
Matched Synonyms: … 5-Methylisoxazole-4-carboxylic acid (4-trifluoromethyl)anilide ... alpha,alpha,alpha-Trifluoro-5-methyl-4-isoxazolecarboxy-p-toluidide ... 4-ISOXAZOLECARBOXAMIDE, 5-METHYL-N-(4-(TRIFLUOROMETHYL)PHENYL)- …
Matched Iupac: … 5-methyl-N-[4-(trifluoromethyl)phenyl]-1,2-oxazole-4-carboxamide …
Matched Description: … drug) class of drugs, which are chemically and pharmacologically very heterogeneous. ... Leflunomide was approved by FDA and in many other countries (e.g., Canada, Europe) in 1999. ... Leflunomide is a pyrimidine synthesis inhibitor belonging to the DMARD (disease-modifying antirheumatic …
Matched Categories: … Leflunomide and metabolite ... Antineoplastic and Immunomodulating Agents …
Matched Products: … Apo-leflunomide ... LEFLUNOMID ABZ 10MG ... LEFLUNOMID AL 10MG FILMTAB …

BQ-788

Investigational
Matched Synonyms: … (((2r,6s)-2,6-dimethyl-1-piperidinyl)carbonyl)-4-methyl-l-leucyl-1-(methoxycarbonyl)-d-tryptophyl-, sodium …
Matched Iupac: … sodium (2R)-2-[(2R)-2-[(2S)-2-{[(2R,6S)-2,6-dimethylpiperidine-1-carbonyl]amino}-4,4-dimethylpentanamido …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Colesevelam

Colesevelam is a bile acid sequestrant. Colesevelam is used with exercise and diet changes (restriction of cholesterol and fat intake) to reduce the amount of cholesterol and certain fatty substances in the blood. It works by binding bile acids in the intestine. Bile acids are made when cholesterol is broken...
Approved
Matched Description: … Colesevelam is used with exercise and diet changes (restriction of cholesterol and fat intake) to reduce ... the amount of cholesterol and certain fatty substances in the blood. ... Colesevelam is a bile acid sequestrant. …
Matched Salts name: … Colesevelam hydrochloride …
Matched Categories: … Bile Acid Sequestrants ... Bile-acid Binding Activity …
Matched Products: … Apo-colesevelam ... Colesevelam Hydrochloride ... Colesevelam hydrochloride …

Cyclic GMP

Cyclic guanosine monophosphate (Cyclic GMP) is a guanine nucleotide containing one phosphate group which is esterified to the sugar moiety in both the 3'- and 5'-positions. It is a cellular regulatory agent and has been described as a second messenger. Its levels increase in response to a variety of hormones,...
Experimental
Matched Synonyms: … Guanosine 3',5'-cyclic phosphate ... 3',5'-cyclic GMP ... Guanosine 3',5'-cyclic monophosphate …
Matched Description: … is esterified to the sugar moiety in both the 3'- and 5'-positions. ... It is a cellular regulatory agent and has been described as a second messenger. ... Its levels increase in response to a variety of hormones, including acetylcholine, insulin, and oxytocin …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …

PIK-75

PIK-75 is a preferential p110 alpha/gamma PI3K inhibitor.
Investigational
Matched Synonyms: … Benzenesulfonic acid, 2-methyl-5-nitro-, 2-((6-bromoimidazo(1,2-a)pyridin-3-yl)methylene)-1-methylhydrazide …
Matched Iupac: … N'-[(E)-{6-bromoimidazo[1,2-a]pyridin-3-yl}methylidene]-N,2-dimethyl-5-nitrobenzene-1-sulfonohydrazide …
Matched Description: … PIK-75 is a preferential p110 alpha/gamma PI3K inhibitor.[A253097] …

Iotroxic acid

Iotroxic acid is a contrast medium molecule.
Experimental
Withdrawn
Matched Synonyms: … Iotroxic acid ... Acido iotroxico ... Acide iotroxique …
Matched Name: … Iotroxic acid …
Matched Iupac: … (2-{[(3-carboxy-2,4,6-triiodophenyl)carbamoyl]methoxy}ethoxy)ethoxy]acetamido}-2,4,6-triiodobenzoic acid …
Matched Description: … Iotroxic acid is a contrast medium molecule. …
Matched Categories: … Compounds used in a research, industrial, or household setting ... Acids, Carbocyclic ... Carboxylic Acids ... iotroxic acid ... Triiodobenzoic Acids …

Pamidronic acid

Pamidronic acid is a second generation, nitrogen containing bisphosphonate similar to neridronic acid and alendronic acid. Pamidronic acid was first described in the literature in 1977. The second generation bisphosphonates are less common as third generation bisphosphonates, such as ibandronic acid, zoledronic acid, minodronic acid, and risedronic acid are becoming...
Approved
Matched Synonyms: … Acide pamidronique ... Pamidronic acid ... Acido pamidronico …
Matched Name: … Pamidronic acid …
Matched Iupac: … (3-amino-1-hydroxy-1-phosphonopropyl)phosphonic acid …
Matched Description: … ] and [alendronic acid]. ... such as [ibandronic acid], [zoledronic acid], [minodronic acid], and [risedronic acid] are becoming more ... Pamidronic acid is a second generation, nitrogen containing bisphosphonate similar to [neridronic acid …
Matched Categories: … Drugs Affecting Bone Structure and Mineralization ... pamidronic acid …
Matched Products: … ./5 มล., 30 มก./10 มล. …

alpha-D-glucose-1-phosphate

Experimental
Matched Synonyms: … glucose-1-phosphate …
Matched Name: … alpha-D-glucose-1-phosphate …
Matched Iupac: … {[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}phosphonic acid …
Matched Salts name: … alpha-Glucose-1-phosphate disodium tetrahydrate …
Matched Categories: … Sugar Phosphates …
Matched Products: … Glucose-1-phosphat "Fresenius" 1 molar - Infusionszusatz - Ampullen …

Tiludronic acid

Tiludronate, or (4-chlorophenyl)thio-methylene-1,1-bisphosphonate, is a first generation bisphosphonate similar to etidronic acid and clodronic acid.[A1923,A203111] These drugs were developed to mimic the action of pyrophosphate, a regulator of calcification and decalcification. Tiludronic acid was first described in the literature in 1988 as a potential treatment for Paget's disease of bone....
Approved
Investigational
Vet approved
Matched Synonyms: … Acide tiludronique ... Tiludronic acid ... Acido tiludronico …
Matched Name: … Tiludronic acid …
Matched Iupac: … {[(4-chlorophenyl)sulfanyl](phosphono)methyl}phosphonic acid …
Matched Description: … similar to [etidronic acid] and [clodronic acid]. ... and decalcification. ... [A1923] Tiludronic acid was first described in the literature in 1988 as a potential treatment for Paget's …
Matched Categories: … Drugs Affecting Bone Structure and Mineralization ... tiludronic acid ... Drugs that are Mainly Renally Excreted ... Phospholipases A, antagonists & inhibitors …

Niflumic acid

Niflumic acid is an analgesic and anti-inflammatory agent used in the treatment of rheumatoid arthritis.
Experimental
Matched Synonyms: … Niflumic acid ... Acido niflumico ... Acide niflumique …
Matched Name: … Niflumic acid …
Matched Iupac: … 2-{[3-(trifluoromethyl)phenyl]amino}pyridine-3-carboxylic acid …
Matched Description: … Niflumic acid is an analgesic and anti-inflammatory agent used in the treatment of rheumatoid arthritis …
Matched Categories: … Niflumic Acid and Prodrugs ... Antiinflammatory and Antirheumatic Products ... Topical Products for Joint and Muscular Pain ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... Acids, Carbocyclic …

Hemoglobin crosfumaril

Hemoglobin in which the alpha-subunit are cross-linked intramolecularly.
Experimental
Matched Synonyms: … Hemoglobin A0 (human alpha2 beta2 tetrameric subunit), alpha-chain 99,99'-diamide with (E)-2-butenoic ... acid …
Matched Description: … Hemoglobin in which the alpha-subunit are cross-linked intramolecularly. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Related Products ... Blood and Blood Forming Organs ... Blood Substitutes and Perfusion Solutions ... Blood Substitutes and Plasma Protein Fractions …

Nicardipine

A potent calcium channel blockader with marked vasodilator action. It has antihypertensive properties and is effective in the treatment of angina and coronary spasms without showing cardiodepressant effects. It has also been used in the treatment of asthma and enhances the action of specific antineoplastic agents. [PubChem]
Approved
Investigational
Matched Iupac: … 3-{2-[benzyl(methyl)amino]ethyl} 5-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate …
Matched Description: … It has antihypertensive properties and is effective in the treatment of angina and coronary spasms without ... It has also been used in the treatment of asthma and enhances the action of specific antineoplastic agents ... A potent calcium channel blockader with marked vasodilator action. …
Matched Salts name: … Nicardipine Hydrochloride …
Matched Categories: … Calcium-Regulating Hormones and Agents ... Adrenergic alpha-Antagonists ... Adrenergic alpha-1 Receptor Antagonists …
Matched Products: … Nicardipine Hydrochloride ... NICARDIPINE HYDROCHLORIDE …

Epoprostenol

A prostaglandin that is a powerful vasodilator and inhibits platelet aggregation. It is biosynthesized enzymatically from prostaglandin endoperoxides in human vascular tissue. The sodium salt has been also used to treat primary pulmonary hypertension.
Approved
Matched Synonyms: … (5Z,9α,11α,13E,15S)-6,9-epoxy-11,15-dihydroxyprosta-5,13-dien-1-oic acid ... (5Z,13E)-(15S)-6,9alpha-Epoxy-11alpha,15-dihydroxyprosta-5,13-dienoate …
Matched Iupac: … ylidene]pentanoic acid ... 5-[(2Z,3aR,4R,5R,6aS)-5-hydroxy-4-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-hexahydro-2H-cyclopenta[b]furan-2- …
Matched Description: … A prostaglandin that is a powerful vasodilator and inhibits platelet aggregation. ... The sodium salt has been also used to treat primary pulmonary hypertension. …
Matched Salts name: … Epoprostenol sodium …
Matched Categories: … Blood and Blood Forming Organs ... Fatty Acids ... Fatty Acids, Unsaturated ... Drugs that are Mainly Renally Excreted …
Matched Products: … Epoprostenol Sodium …

EF-022

EF-022 is a modified version of vitamin D binding protein macrophage activator, with potential antineoplastic and anti-angiogenic activities.
Investigational
Matched Synonyms: … Modified vitamin D binding protein ... Modified Vitamin D Binding Protein Macrophage Activator …
Matched Description: … and anti-angiogenic activities. ... EF-022 is a modified version of vitamin D binding protein macrophage activator, with potential antineoplastic …

Chloramphenicol

An antibiotic first isolated from cultures of Streptomyces venezuelae in 1947 but now produced synthetically. It has a relatively simple structure and was the first broad-spectrum antibiotic to be discovered. It acts by interfering with bacterial protein synthesis and is mainly bacteriostatic. (From Martindale, The Extra Pharmacopoeia, 29th ed, p106)...
Approved
Vet approved
Withdrawn
Matched Description: … It has a relatively simple structure and was the first broad-spectrum antibiotic to be discovered. ... It acts by interfering with bacterial protein synthesis and is mainly bacteriostatic. ... An antibiotic first isolated from cultures of _Streptomyces venezuelae_ in 1947 but now produced synthetically …
Matched Categories: … Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics ... Ophthalmological and Otological Preparations …
Matched Products: … CHLORAMPHENICOL PALMITATE ... KLORA KAPSÜL, 500 ADET ... ENCLOR EAR DROPS 5% W/V …

Sulfuric acid

Experimental
Matched Synonyms: … Acido sulfurico ... Acide sulfurique ... Brimstone acid …
Matched Name: … Sulfuric acid …
Matched Iupac: … sulfuric acid …
Matched Categories: … Acids ... Sulfur Acids ... Acids, Noncarboxylic …

Metamfetamine

Metamfetamine (methamphetamine) is a psychostimulant and sympathomimetic drug, and a member of the amphetamine group of sympathomimetic amines. Methamphetamine can induce effects such as euphoria, increased alertness and energy, and enhanced self-esteem. It is a scheduled drug in most countries due to its high potential for addiction and abuse. The...
Approved
Illicit
Withdrawn
Matched Description: … hydrochloride, a metamfetamine salt. ... Metamfetamine (methamphetamine) is a psychostimulant and sympathomimetic drug, and a member of the amphetamine ... Methamphetamine can induce effects such as euphoria, increased alertness and energy, and enhanced self-esteem …
Matched Salts cas: … 51-57-0 …
Matched Salts name: … Metamfetamine hydrochloride …
Matched Categories: … Psychostimulants, Agents Used for ADHD and Nootropics ... Adrenergic alpha-Agonists ... Adrenergic alpha-2 Receptor Agonists ... Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates ... Drugs that are Mainly Renally Excreted …
Matched Products: … Methamphetamine Hydrochloride …

Berberine

An alkaloid from Hydrastis canadensis L., Berberidaceae. It is also found in many other plants. It is relatively toxic parenterally, but has been used orally for various parasitic and fungal infections and as antidiarrheal.
Approved
Investigational
Matched Iupac: … 16,17-dimethoxy-5,7-dioxa-13lambda5-azapentacyclo[11.8.0.0^{2,10}.0^{4,8}.0^{15,20}]henicosa-1(21),2,4 …
Matched Description: … and as antidiarrheal. ... It is relatively toxic parenterally, but has been used orally for various parasitic and fungal infections ... An alkaloid from Hydrastis canadensis L., Berberidaceae. It is also found in many other plants. …
Matched Products: … Berberine Hydrochloride Granular …

7-alpha-D-Ribofuranosyl-2-aminopurine-5'-phosphate

Experimental
Matched Name: … 7-alpha-D-Ribofuranosyl-2-aminopurine-5'-phosphate …
Matched Iupac: … {[(2R,3S,4R,5S)-5-(2-amino-7H-purin-7-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}phosphonic acid …

Daptomycin

Daptomycin is a cyclic lipopeptide antibacterial agent with a broad spectrum of activity against Gram-positive bacteria, including methicillin-susceptible and -resistant Staphylococcus aureus (MSSA/MRSA) and vancomycin-resistant Enterococci (VRE).[A231379, A231384, L32534] Chemically, daptomycin comprises 13 amino acids, including several non-standard and D-amino acids, with the C-terminal 10 amino acids forming an ester-linked...
Approved
Investigational
Matched Iupac: … carbamoyl}-3-[(2R)-3-carbamoyl-2-[(2S)-2-decanamido-3-(1H-indol-3-yl)propanamido]propanamido]propanoic acid …
Matched Description: … and D-amino acids, with the C-terminal 10 amino acids forming an ester-linked ring and the N-terminal ... bacteria, including methicillin-susceptible and -resistant _Staphylococcus aureus_ (MSSA/MRSA) and vancomycin-resistant ... [A231379] Daptomycin was approved by the FDA on September 12, 2003, and is marketed under the name …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Drugs that are Mainly Renally Excreted …
Matched Products: … Daptomycin in Sodium Chloride ... CUBICIN® 350 MG POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCIÓN INYECTABLE ... DATABIN® 500 MG …

Sertraline

Sertraline is a popular antidepressant medication commonly known as a selective serotonin reuptake inhibitor (SSRI), and is similar to drugs such as Citalopram and Fluoxetine. Despite marked structural differences between compounds in this drug class, SSRIs exert similar pharmacological effects. Several weeks of therapy with sertraline may be required before...
Approved
Matched Description: … (SSRI), and is similar to drugs such as [Citalopram] and [Fluoxetine]. ... classes of antidepressants, which frequently cause high levels of drowsiness, dizziness, blurred vision, and ... Sertraline is a popular antidepressant medication commonly known as a selective serotonin reuptake inhibitor …
Matched Salts name: … Sertraline hydrochloride …
Matched Categories: … Monoamine Oxidase A Substrates …
Matched Products: … Sertraline Hydrochloride ... Sertraline hydrochloride ... SERTRAline Hydrochloride …

Cevimeline

Cevimeline is a parasympathomimetic agent that act as an agonist at the muscarinic acetylcholine receptors M1 and M3. It is indicated by the Food and Drug Administration for the treatment of dry mouth associated with Sjögren's syndrome.
Approved
Matched Synonyms: … 2-Methyspiro(1,3-oxathiolane-5,3)quinuclidine …
Matched Iupac: … (2R)-5'-methyl-4-azaspiro[bicyclo[2.2.2]octane-2,2'-[1,4]oxathiolane] …
Matched Description: … M1 and M3. ... It is indicated by the Food and Drug Administration for the treatment of dry mouth associated with Sjögren's ... Cevimeline is a parasympathomimetic agent that act as an agonist at the muscarinic acetylcholine receptors …
Matched Salts name: … Cevimeline hydrochloride …
Matched Categories: … Drugs that are Mainly Renally Excreted …
Matched Products: … Cevimeline Hydrochloride …

Rimantadine

An RNA synthesis inhibitor that is used as an antiviral agent in the prophylaxis and treatment of influenza.
Approved
Investigational
Matched Synonyms: … alpha-Methyladamantanemethylamine ... alpha-Methyl-1-adamantanemethylamine …
Matched Description: … An RNA synthesis inhibitor that is used as an antiviral agent in the prophylaxis and treatment of influenza …
Matched Salts name: … Rimantadine hydrochloride …
Matched Categories: … Influenza A M2 Protein Inhibitor ... Nucleic Acid Synthesis Inhibitors …
Matched Products: … Rimantadine Hydrochloride …

Dapiprazole

Dapiprazole (U.S. trade name Rev-Eyes) is an alpha blocker. It is found in ophthalmic solutions used to reverse mydriasis after an eye examination.
Approved
Matched Synonyms: … 5,6,7,8-Tetrahydro-3-(2-(4-(o-tolyl)-1-piperazinyl)ethyl)-s-triazolo(4,3-a)pyridine …
Matched Iupac: … 1-(2-methylphenyl)-4-(2-{5H,6H,7H,8H-[1,2,4]triazolo[4,3-a]pyridin-3-yl}ethyl)piperazine …
Matched Description: … Dapiprazole (U.S. trade name Rev-Eyes) is an alpha blocker. ... It is found in ophthalmic solutions used to reverse mydriasis after an eye examination. …
Matched Salts name: … Dapiprazole hydrochloride …
Matched Categories: … Antiglaucoma Preparations and Miotics ... Adrenergic alpha-Antagonists ... Adrenergic alpha-1 Receptor Antagonists …

Monensin

Monensin is a polyether isolated from Streptomyces cinnamonensis that presents antibiotic properties. It is widely used in ruminant animal feeds.
Experimental
Vet approved
Matched Synonyms: … Monensin A ... Monensic acid …
Matched Iupac: … -7-yl]-3-methoxy-2-methylpentanoic acid ... (2S,3R,4S)-4-[(2S,5R,7S,8R,9S)-2-[(2S,2'R,3'S,5R,5'R)-2-ethyl-5'-[(2S,3S,5R,6R)-6-hydroxy-6-(hydroxymethyl ... )-3,5-dimethyloxan-2-yl]-3'-methyl-[2,2'-bioxolan]-5-yl]-9-hydroxy-2,8-dimethyl-1,6-dioxaspiro[4.5]decan …
Matched Description: … Monensin is a polyether isolated from _Streptomyces cinnamonensis_ that presents antibiotic properties …
Matched Salts name: … Monensin sodium …
Matched Categories: … Sodium Ionophores ... Compounds used in a research, industrial, or household setting ... Acids, Acyclic ... Fatty Acids ... Carboxylic Acids …
Displaying drugs 901 - 925 of 5411 in total