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Displaying drugs 9501 - 9525 of 10304 in total
Ralimetinib has been used in trials studying the treatment of Postmenopausal, Advanced Cancer, Adult Glioblastoma, Fallopian Tube Cancer, and Metastatic Breast Cancer, among others.
Investigational
Matched Iupac: … 5-[2-tert-butyl-5-(4-fluorophenyl)-1H-imidazol-4-yl]-3-(2,2-dimethylpropyl)-3H-imidazo[4,5-b]pyridin- ... 2-amine …
Basimglurant has been used in trials studying the diagnostic and treatment of Depression, Fragile X Syndrome, and Major Depressive Disorder.
Investigational
Matched Iupac: … 2-chloro-4-{2-[1-(4-fluorophenyl)-2,5-dimethyl-1H-imidazol-4-yl]ethynyl}pyridine …
Filociclovir is under investigation in clinical trial NCT01433835 (Safety and Pharmacokinetics of Single Oral Doses of Filociclovir in Healthy Volunteers).
Investigational
Matched Iupac: … 2-amino-9-{[(1Z)-2,2-bis(hydroxymethyl)cyclopropylidene]methyl}-6,9-dihydro-1H-purin-6-one …
Experimental
Matched Iupac: … 2-[2,5-bis(aziridin-1-yl)-4-methyl-3,6-dioxocyclohexa-1,4-dien-1-yl]-2-methoxyethyl carbamate …
Experimental
Matched Iupac: … }oxy)(hydroxy)phosphoryl]oxy}methyl)-3,4-dihydroxyoxolan-2-yl]-3-carbamoyl-4-[(2S)-3-oxopentan-2-yl]- ... 1-[(2R,3R,4S,5R)-5-({[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl phosphonato …
Experimental
Matched Name: … 2-Phenylamino-Ethanesulfonic Acid …
Matched Iupac: … 2-(phenylamino)ethane-1-sulfonic acid …
Experimental
Matched Iupac: … {[(2S,3S,4S,5R)-3,4-dihydroxy-5-[(phosphonooxy)methyl]oxolan-2-yl]methoxy}phosphonic acid …
Experimental
Matched Name: … (5-(PYRIDIN-3-YL)FURAN-2-YL)METHANAMINE …
Matched Iupac: … 1-[5-(pyridin-3-yl)furan-2-yl]methanamine …
Experimental
Matched Name: … 6-phenyl-4(R)-(7-phenyl-heptanoylamino)-hexanoic acid …
Matched Iupac: … (4R)-6-phenyl-4-(7-phenylheptanamido)hexanoic acid …
Experimental
Matched Name: … 4-(quinolin-3-ylmethyl)piperidine-1-carboxylic acid …
Matched Iupac: … 4-[(quinolin-3-yl)methyl]piperidine-1-carboxylic acid …
Experimental
Matched Name: … 2-Thiomethyl-3-Phenylpropanoic Acid …
Matched Iupac: … (2S)-2-benzyl-3-sulfanylpropanoic acid …
Experimental
Matched Name: … 2-[(Dioxidophosphoranyl)oxy]benzoate …
Matched Iupac: … 2-[(oxidophosphonoyl)oxy]benzoate …
BNT162b1 is one of four advanced mRNA-based vaccines being developed through "Project Lightspeed," a joint program between Pfizer and BioNTech.[L15002, L15007] BNT162b1 is a nucleoside modified mRNA (modRNA) vaccine encoding the receptor-binding domain (RBD) of the SARS-CoV-2 spike (S) protein together with a "foldon" trimerization domain derived from T4 fibritin...
Investigational
Matched Name: … BNT162b1 SARS-CoV-2 Vaccine …
Matched Description: … nucleoside modified mRNA (modRNA) vaccine encoding the receptor-binding domain (RBD) of the SARS-CoV-2 ... [L15007, L15012] Early results from a phase 1/2 study in 45 healthy adult volunteers demonstrated RBD-binding …
Experimental
Matched Iupac: … 2-amino-9-[(2R,3R,4S,5R)-5-({[({[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl] ... (hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)(hydroxy)phosphoryl]oxy}methyl)-3,4-dihydroxyoxolan-2- …
Guanosine 5'-(trihydrogen diphosphate), monoanhydride with phosphorothioic acid. A stable GTP analog which enjoys a variety of physiological actions such as stimulation of guanine nucleotide-binding proteins, phosphoinositide hydrolysis, cyclic AMP accumulation, and activation of specific proto-oncogenes.
Experimental
Matched Iupac: … ({[({[(2R,3S,4R,5R)-5-(2-amino-6-oxo-6,9-dihydro-1H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy …
Acetrizoic acid presents the molecular formula of 3-acetamidol-2,4,6-triiodobenzoic acid and it is the first monomeric ionic compound used as an X-ray contrast agent. It was first synthesized by Wallingford in 1953 and it was filled in the FDA by the Johnson & Johnson subsidiary, Cilag Chemie AG, on February 8th,...
Withdrawn
Experimental
Matched Iupac: … (5R,6R,7S,8S)-5-(hydroxymethyl)-2-[(phenylamino)methyl]-5H,6H,7H,8H-imidazo[1,2-a]pyridine-6,7,8-triol …
MK0249 has been used in trials studying the treatment of Hypopnea Syndrome, Alzheimer's Disease, Paranoid Schizophrenia, Sleep Apnea, Obstructive, and Excessive Daytime Sleepiness, among others.
Investigational
Matched Iupac: … 2-methyl-3-{4-[3-(pyrrolidin-1-yl)propoxy]phenyl}-5-(trifluoromethyl)-3,4-dihydroquinazolin-4-one …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Aceprometazine is a is a drug with neuroleptic and anti-histamine properties. Although not widely prescribed, it is used in combination with meprobamate for the treatment of sleep disorders in France under the trade name Mepronizine.
Experimental
Matched Synonyms: … 10-(2-(Dimethylamino)propyl)phenothiazin-2-yl methyl ketone …
Matched Iupac: … 1-{10-[2-(dimethylamino)propyl]-10H-phenothiazin-2-yl}ethan-1-one …
An organic compound used often as a reagent in organic synthesis, as a flavoring agent, and in tanning. It has been demonstrated as an intermediate in the metabolism of acetone and its derivatives in isolated cell preparations, in various culture media, and in vivo in certain animals. [PubChem]
Experimental
Matched Synonyms: … 2-oxopropanal ... 2-ketopropionaldehyde …
Matched Iupac: … 2-oxopropanal …
Experimental
Matched Iupac: … (2Z)-2-amino-3-phenylprop-2-enoic acid …
The GX-19 vaccine is a DNA vaccine created by Genexine, Inc. Company in Gyeonggi, Korea . As of June 2020, the vaccine candidate is undergoing Phase I and Phase IIa trials to determine dose levels for safety and efficacy[A219758,L16488].
Investigational
Matched Synonyms: … DNA vaccine expressing SARS-CoV-2 S-protein antigen …
AZD1305 has been used in trials studying the treatment and basic science of Atrial Flutter, Atrial Fibrillation, and Left Ventricle Function.
Investigational
Matched Iupac: … tert-butyl N-{2-[(1R,5S)-7-[2-(4-cyano-2-fluorophenoxy)ethyl]-9-oxa-3,7-diazabicyclo[3.3.1]nonan-3-yl …
Lafutidine has been investigated in Peptic Ulcer, Community-acquired Pneumonia, and Gastroesophageal Reflux Disease (GERD).
Investigational
Matched Iupac: … 2-[(furan-2-yl)methanesulfinyl]-N-[(2Z)-4-({4-[(piperidin-1-yl)methyl]pyridin-2-yl}oxy)but-2-en-1-yl] …
AZD-9977 is under investigation in clinical trial NCT03843060 (A Phase 1 Study to Assess the Pharmacokinetics of AZD9977 Administered Alone and in Combination With Itraconazole in Healthy Volunteers).
Investigational
Matched Iupac: … 2-[(3S)-7-fluoro-4-(3-oxo-3,4-dihydro-2H-1,4-benzoxazine-6-carbonyl)-3,4-dihydro-2H-1,4-benzoxazin-3- ... yl]-N-methylacetamide …
Displaying drugs 9501 - 9525 of 10304 in total