Displaying drugs 951 - 975 of 1654 in total
Ofatumumab
Ofatumumab is a novel anti-CD20 monoclonal antibody that targets B-cells. It is an IgG1κ human monoclonal antibody produced from a recombinant murine cell line (NS0) via transgenic mouse and hybridoma technology. Ofatumumab works by recognizing antigens that are expressed on the tumour cells in certain cancers; however, the antigen is...
Approved
Matched Synonyms: … HuMax-CD20 ... HuMax-CD20, 2F2 …
Matched Description: … It is an IgG1κ human monoclonal antibody produced from a recombinant murine cell line (NS0) via transgenic ... mouse and hybridoma technology. ... In February 2020, FDA and EMA approved Supplemental Biologics License Application (sBLA) and Marketing …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Matched Description: … It is an IgG1κ human monoclonal antibody produced from a recombinant murine cell line (NS0) via transgenic ... mouse and hybridoma technology. ... In February 2020, FDA and EMA approved Supplemental Biologics License Application (sBLA) and Marketing …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
STX-100
STX-100 is under investigation in clinical trial NCT01371305 (STX-100 in Patients With Idiopathic Pulmonary Fibrosis (IPF)).
Investigational
Matched Synonyms: … Humanized monoclonal antibody against human integrin alphaVbeta6 …
TCN-202
Investigational
Matched Synonyms: … TCN-202 (human anti-cytomegalovirus monoclonal antibody) …
Alidornase alfa
Investigational
Matched Synonyms: … Deoxyribonuclease (synthetic human), amide with 1,2-ethanediamine …
CER-001
CER-001 is a negatively charged lipoprotein particle comprising human recombinant apolipoprotein A-I and two phospholipids: sphingomyelin and dipalmitoylphosphatidylglycerol. It is under investigation for the treatment of lecithin-cholesterol acyltransferase (LCAT) deficiencies.
Investigational
Matched Synonyms: … Recombinant human apolipoprotein A-I/phospholipid complexes …
Matched Description: … and two phospholipids: sphingomyelin and dipalmitoylphosphatidylglycerol. ... CER-001 is a negatively charged lipoprotein particle comprising human recombinant apolipoprotein A-I …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … and two phospholipids: sphingomyelin and dipalmitoylphosphatidylglycerol. ... CER-001 is a negatively charged lipoprotein particle comprising human recombinant apolipoprotein A-I …
Matched Categories: … Amino Acids, Peptides, and Proteins …
HH-009
HH-009 is a recombinant human IgG4 monoclonal antibody against FGF19 being studied for the treatment of hepatocellular carcinoma.
Investigational
Matched Synonyms: … recombinant human IgG4 monoclonal antibody against FGF19 …
Matched Description: … HH-009 is a recombinant human IgG4 monoclonal antibody against FGF19 being studied for the treatment …
Matched Description: … HH-009 is a recombinant human IgG4 monoclonal antibody against FGF19 being studied for the treatment …
Ammonia
Ammonia is a naturally-occurring compound with a chemical formula NH3 and structure of trigonal pyramidal geometry. It is a colorless gas with a pungent smell, and become NH4, or ammonium ion, when in water. Although ammonia is used as a food additive in the anhydrous form and serves as a...
Approved
Matched Description: … It is proposed that human adults produce about 1000 mmol of ammonia daily, most of which undergoes excretion ... pharmaceutical and commercial products, it is caustic and hazardous when concentrated. ... matter, including plants, animals, and animal wastes. …
Matched Mixtures name: … Physician EZ Use Joint Tunnel and Trigger Kit ... CVS Health Medication and Topical Refill Pouch ... JTT Physicians Joint, Tunnel and Trigger …
Matched Products: … Humco Aromatic Ammonia Spirit …
Matched Mixtures name: … Physician EZ Use Joint Tunnel and Trigger Kit ... CVS Health Medication and Topical Refill Pouch ... JTT Physicians Joint, Tunnel and Trigger …
Matched Products: … Humco Aromatic Ammonia Spirit …
Drozitumab
Drozitumab is a human monoclonal antibody directed against tumor necrosis factor receptor superfamily member 10B (TNFRSF10B), a member of tumor necrosis factor related apoptosis-inducing ligand (TRAIL). It was developed by Genentech as a drug for the treatment of cancers
Investigational
Matched Synonyms: … ), disulfide with human l3-chain, dimer ... Immunoglobulin g1, anti-(human citokine receptor dr5 (death receptor 5)) (human monoclonal heavy chain …
Matched Description: … Drozitumab is a human monoclonal antibody directed against tumor necrosis factor receptor superfamily …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … Drozitumab is a human monoclonal antibody directed against tumor necrosis factor receptor superfamily …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Quisovalimab
Investigational
Matched Synonyms: … TNFSF14) (human-Mus musculus monoclonal SAR252067 γ4-chain), disulfide with human-Mus musculus monoclonal ... Immunoglobulin G4 [230-proline,237-glutamic acid], anti-(human tumor necrosis factor superfamily protein …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
L-N(omega)-Nitroarginine-2,4-L-diaminobutyric amide
Experimental
Matched Name: … L-N(omega)-Nitroarginine-2,4-L-diaminobutyric amide …
delta-(L-alpha-Aminoadipoyl)-L-cysteinyl-D-vinylglycine
Experimental
Matched Name: … delta-(L-alpha-Aminoadipoyl)-L-cysteinyl-D-vinylglycine …
(2S,3S)-2-azanyl-3-methyl-pentanedioic acid
Experimental
Matched Synonyms: … (3S)-3-methyl-L-glutamic acid …
Calcium threonate
Calcium threonate is a calcium salt of threnoic acid and a novel drug developed for the treatment of osteoporosis and as a calcium supplement . It is found in dietary supplements as a source of L-threonate used in the treatment of calcium deficiency and prevention of osteoporosis. The most common...
Approved
Matched Synonyms: … Calcium L-threonate …
Matched Description: … and prevention of osteoporosis. ... osteoporosis and as a calcium supplement [A27266]. ... Calcium threonate is a calcium salt of threnoic acid and a novel drug developed for the treatment of …
Matched Mixtures name: … and Succinic Acid ... Threonate and Succinic Acid ... Iron Aspartate, Glycinate, Ascorbic Calcium, Vitamin B12, Calcium Threonate and Succinic Acid …
Matched Description: … and prevention of osteoporosis. ... osteoporosis and as a calcium supplement [A27266]. ... Calcium threonate is a calcium salt of threnoic acid and a novel drug developed for the treatment of …
Matched Mixtures name: … and Succinic Acid ... Threonate and Succinic Acid ... Iron Aspartate, Glycinate, Ascorbic Calcium, Vitamin B12, Calcium Threonate and Succinic Acid …
Selegiline
A selective, irreversible inhibitor of Type B monoamine oxidase. It is used in newly diagnosed patients with Parkinson's disease. It may slow progression of the clinical disease and delay the requirement for levodopa therapy. It also may be given with levodopa upon onset of disability. (From AMA Drug Evaluations Annual,...
Approved
Investigational
Vet approved
Matched Synonyms: … L-Deprenalin …
Matched Description: … It may slow progression of the clinical disease and delay the requirement for levodopa therapy. …
Matched Description: … It may slow progression of the clinical disease and delay the requirement for levodopa therapy. …
Mecasermin
Mecasermin contains recombinant-DNA-engineered human insulin-like growth factor-1 (rhIGF-1)[FDA Label]. IGF-1 consists of 70 amino acids in a single chain with three intramolecular disulfide bridges and a molecular weight of 7649 daltons. The amino acid sequence of the product is identical to that of endogenous human IGF-1. The rhIGF-1 protein is...
Approved
Investigational
Matched Synonyms: … Human somatomedin C ... INSULIN-LIKE GROWTH FACTOR I (HUMAN) ... RECOMBINANT HUMAN INSULIN-LIKE GROWTH FACTOR-I …
Matched Description: … IGF-1 consists of 70 amino acids in a single chain with three intramolecular disulfide bridges and a ... The amino acid sequence of the product is identical to that of endogenous human IGF-1. ... Mecasermin contains recombinant-DNA-engineered human insulin-like growth factor-1 (rhIGF-1)[FDA Label …
Matched Categories: … Human Insulin-like Growth Factor Analogs ... Recombinant Human Insulin-like Growth Factor-1 ... Pituitary and Hypothalamic Hormones and Analogues ... Amino Acids, Peptides, and Proteins ... Sex Hormones and Insulins …
Matched Description: … IGF-1 consists of 70 amino acids in a single chain with three intramolecular disulfide bridges and a ... The amino acid sequence of the product is identical to that of endogenous human IGF-1. ... Mecasermin contains recombinant-DNA-engineered human insulin-like growth factor-1 (rhIGF-1)[FDA Label …
Matched Categories: … Human Insulin-like Growth Factor Analogs ... Recombinant Human Insulin-like Growth Factor-1 ... Pituitary and Hypothalamic Hormones and Analogues ... Amino Acids, Peptides, and Proteins ... Sex Hormones and Insulins …
Gresonitamab
Investigational
Matched Synonyms: … IMMUNOGLOBULIN, BISPECIFIC, ANTI-(HUMAN CLAUDIN 18.2) (HUMAN MONOCLONAL HWZV_KLA_L SINGLE-CHAIN VARIABLE ... VH1-(GGGGS)3-VL1) FUSION PROTEIN WITH PEPTIDE LINKER (GGGGS) FUSION PROTEIN WITH IMMUNOGLOBULIN ANTI-(HUMAN …
Vepsitamab
Investigational
Matched Synonyms: … IMMUNOGLOBULIN, BISPECIFIC, ANTI-(HUMAN MUCIN 17) (HUMAN MONOCLONAL MUC17_CD3_ALT2 SINGLE-CHAIN VARIABLE ... VH1-(GGGGS)3-VL1) FUSION PROTEIN WITH PEPTIDE LINKER (GGGGS) FUSION PROTEIN WITH IMMUNOGLOBULIN ANTI-(HUMAN …
Asparaginase Erwinia chrysanthemi
Asparaginase Erwinia chrysanthemi is an asparaginase-specific enzyme derived from Erwinia chrysanthemi used as an anticancer agent. It works by depleting the stores of an important amino acid called asparagine, which is involved in DNA synthesis and cell survival of malignant cells, leading to cell death. L-asparaginase was first identified in...
Approved
Investigational
Matched Synonyms: … Erwinia L-asparaginase ... L-asparaginase (Erwinia) ... L-asparaginase, Erwinia chrysanthemi …
Matched Description: … [L1448] L-asparaginase was first identified in 1963,[A236344] and there are different formulations of ... L-asparaginase, including [Asparaginase Escherichia coli] and a pegylated form of this enzyme, [Pegaspargase ... depleting the stores of an important amino acid called asparagine, which is involved in DNA synthesis and …
Matched Categories: … Enzymes and Coenzymes …
Matched Description: … [L1448] L-asparaginase was first identified in 1963,[A236344] and there are different formulations of ... L-asparaginase, including [Asparaginase Escherichia coli] and a pegylated form of this enzyme, [Pegaspargase ... depleting the stores of an important amino acid called asparagine, which is involved in DNA synthesis and …
Matched Categories: … Enzymes and Coenzymes …
Nacystelyn
Investigational
Matched Synonyms: … L-lysine, compd. with n-acetyl-l-cysteine …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Metyrosine
An inhibitor of the enzyme tyrosine 3-monooxygenase, and consequently of the synthesis of catecholamines. It is used to control the symptoms of excessive sympathetic stimulation in patients with pheochromocytoma. (Martindale, The Extra Pharmacopoeia, 30th ed)
Approved
Matched Synonyms: … (–)-α-methyl-L-tyrosine ... α-methyl-L-p-tyrosine ... (-)-alpha-Methyl-L-tyrosine …
Matched Description: … An inhibitor of the enzyme tyrosine 3-monooxygenase, and consequently of the synthesis of catecholamines …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … An inhibitor of the enzyme tyrosine 3-monooxygenase, and consequently of the synthesis of catecholamines …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Z-Val-Ala-Asp fluoromethyl ketone
Non-methylated, competitive, and irreversible inhibitor of caspase 1, as well as other caspases,1 which can be used directly with purified enzymes. It does not require an esterase to hydrolyze the O-methyl ester like the cell-permeable form, Z-Val-Ala-Asp(O-Me) fluoromethyl ketone.
Experimental
Matched Synonyms: … N-[(Benzyloxy)carbonyl]-L-valyl-N-[(2S)-1-carboxy-4-fluoro-3-oxo-2-butanyl]-L-alaninamide …
Matched Description: … Non-methylated, competitive, and irreversible inhibitor of caspase 1, as well as other caspases,1 which …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … Non-methylated, competitive, and irreversible inhibitor of caspase 1, as well as other caspases,1 which …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Fecal microbiota
Fecal microbiota, given either as a rectal transplant or in an oral formulation of live spores, is an FDA-approved option to prevent the recurrence of Clostridioides difficile infection (CDI) in patients given an antibacterial treatment for recurrent CDI.[A259182,L46217,L46222] Although the incidence of CDI has declined and the number of cases...
Approved
Investigational
Matched Synonyms: … Donor human stool ... Donor human stool spores (ethanol treated) …
Matched Description: … Human fecal matter is then tested for a panel of transmissible pathogens and processed with methods aimed ... Recurrent CDI has a high risk of mortality and a high failure rate. ... [A259182,L46217,L46222] Although the incidence of CDI has declined and the number of cases requiring …
Matched Description: … Human fecal matter is then tested for a panel of transmissible pathogens and processed with methods aimed ... Recurrent CDI has a high risk of mortality and a high failure rate. ... [A259182,L46217,L46222] Although the incidence of CDI has declined and the number of cases requiring …
Allogenic Human Umbilical Derived Mesenchymal Stem Cells in Conditioned Media
Umbilical-cord derived MSCs are currently being tested for numerous clinical applications due to their immunosuppressive and anti-inflammatory properties. In comparison to bone-marrow derived MSCs, these cells are more resilient, easier to extract, and generally regarded as less immunogenic. The condition medium (CM) derived from these MSCs has also been implicated...
Investigational
Matched Synonyms: … Allogeneic Human Umbilical Derived Mesenchymal Stem Cells in Conditioned Media ... Allogenic Human Umbilical Derived Mesenchymal Stem Cells in Conditioned Media …
Matched Name: … Allogenic Human Umbilical Derived Mesenchymal Stem Cells in Conditioned Media …
Matched Description: … derived MSCs are currently being tested for numerous clinical applications due to their immunosuppressive and ... In comparison to bone-marrow derived MSCs, these cells are more resilient, easier to extract, and generally …
Matched Name: … Allogenic Human Umbilical Derived Mesenchymal Stem Cells in Conditioned Media …
Matched Description: … derived MSCs are currently being tested for numerous clinical applications due to their immunosuppressive and ... In comparison to bone-marrow derived MSCs, these cells are more resilient, easier to extract, and generally …
Asparagine
A non-essential amino acid that is involved in the metabolic control of cell functions in nerve and brain tissue. It is biosynthesized from aspartic acid and ammonia by asparagine synthetase. (From Concise Encyclopedia Biochemistry and Molecular Biology, 3rd ed)
Approved
Investigational
Nutraceutical
Matched Synonyms: … L-Asparagine ... L-aspartic acid β-amide ... L-2-aminosuccinamic acid …
Matched Description: … (From Concise Encyclopedia Biochemistry and Molecular Biology, 3rd ed) ... It is biosynthesized from aspartic acid and ammonia by asparagine synthetase. ... A non-essential amino acid that is involved in the metabolic control of cell functions in nerve and brain …
Matched Mixtures name: … ., Ltd. ... ., Ltd. ... ., Ltd. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … (From Concise Encyclopedia Biochemistry and Molecular Biology, 3rd ed) ... It is biosynthesized from aspartic acid and ammonia by asparagine synthetase. ... A non-essential amino acid that is involved in the metabolic control of cell functions in nerve and brain …
Matched Mixtures name: … ., Ltd. ... ., Ltd. ... ., Ltd. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Pegaspargase
Pegaspargase is a conjugate of monomethoxypolyethylene glycol (mPEG) and L-asparaginase (L-asparagine amidohydrolase), an asparagine-specific enzyme that converts L-asparagine into aspartic acid and ammonia. Asparagine is an amino acid that is vital for cell survival. In humans, most normal tissues can produce asparagine through the action of asparagine synthetase. However, leukemia...
Approved
Investigational
Matched Synonyms: … Peg/L-asparaginase …
Matched Description: … Pegaspargase is a conjugate of monomethoxypolyethylene glycol (mPEG) and L-asparaginase (L-asparagine ... reducing immune detection, and it also increases the half-life of L-asparaginase. ... However, leukemia cells have low levels of this enzyme and depend on exogenous sources. …
Matched Categories: … Enzymes and Coenzymes ... Antineoplastic and Immunomodulating Agents …
Matched Description: … Pegaspargase is a conjugate of monomethoxypolyethylene glycol (mPEG) and L-asparaginase (L-asparagine ... reducing immune detection, and it also increases the half-life of L-asparaginase. ... However, leukemia cells have low levels of this enzyme and depend on exogenous sources. …
Matched Categories: … Enzymes and Coenzymes ... Antineoplastic and Immunomodulating Agents …
Displaying drugs 951 - 975 of 1654 in total