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Displaying drugs 9726 - 9750 of 11213 in total
Dexelvucitabine has been used in trials studying the treatment of HIV Infections and Human Immunodeficiency Virus.
Investigational
Matched Iupac: … 4-amino-5-fluoro-1-[(2R,5S)-5-(hydroxymethyl)-2,5-dihydrofuran-2-yl]-1,2-dihydropyrimidin-2-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Brilacidin is under investigation for the supportive care of Mucositis, Stomatitis, Mouth Diseases, and Head and Neck Neoplasms.
Investigational
Matched Iupac: … N4,N6-bis[3-(5-carbamimidamidopentanamido)-2-[(3R)-pyrrolidin-3-yloxy]-5-(trifluoromethyl)phenyl]pyrimidine …
Matched Salts cas: … 1224095-99-1
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Experimental
Matched Iupac: … 5-(2-bromoprop-2-en-1-yl)-1-methyl-5-(propan-2-yl)-1,3-diazinane-2,4,6-trione …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
PF-05241328 is under investigation in clinical trial NCT01165736 (To Calculate the Pharmacokinetics (Concentration of Compound in and Rate of Excretion From the Blood) Following a Very Low Dose of Compound Which Will Not Have Any Pharmacological Activity).
Investigational
Matched Iupac: … 1-[5-chloro-6-(2-methylpropoxy)pyridin-3-yl]-N-methanesulfonyl-3-methyl-1H-indazole-5-carboxamide …
Investigational
Matched Iupac: … 5-{[4-({[(2R)-morpholin-2-yl]methyl}amino)-5-(trifluoromethyl)pyridin-2-yl]amino}pyrazine-2-carbonitrile …
Decoglurant has been used in trials studying the treatment of Major Depressive Disorder.
Investigational
Matched Iupac: … 5-{2-[7-(trifluoromethyl)-5-[4-(trifluoromethyl)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]ethynyl}pyridin- ... 2-amine …
Experimental
Matched Synonyms: … 3-Benzylthioalanine …
Matched Iupac: … (2R)-2-amino-3-(benzylsulfanyl)propanoic acid …
Desmoteplase is a chemical in the saliva of vampire bats. It activates plasminogen to the serine protease, plasmin. Plasmin acts by breaking down fibrin blood clots. When a vampire bat bites its victim, it secretes an enzyme that prevents the blood from clotting. The enzyme is called DSPA (Desmodus rotundus...
Investigational
Matched Synonyms: … rDSPA alpha 1 ... Salivary plasminogen activator alpha 1, Desmodus rotundus …
Matched Description: … Desmoteplase is a recombinant form of vampire bat DSPA (Salivary plasminogen activator alpha 1). …
Phenothiazine (PTZ) is an organic thiazine compound.
Experimental
Vet approved
Matched Categories: … Heterocyclic Compounds, 3-Ring …
Experimental
Matched Iupac: … (2S,3R,4R,5S,6R)-6-(hydroxymethyl)-2-methoxy-5-sulfanyloxane-3,4-diol …
Fresolimumab has been used in trials studying the treatment of Primary Brain Tumors, Metastatic Breast Cancer, Diffuse Systemic Sclerosis, Pleural Malignant Mesothelioma, and Primary Focal Segmental Glomerulosclerosis.
Investigational
Experimental
Matched Name: … D-phenylalanyl-N-(3-methylbenzyl)-L-prolinamide …
Matched Iupac: … (2S)-1-[(2R)-2-amino-3-phenylpropanoyl]-N-[(3-methylphenyl)methyl]pyrrolidine-2-carboxamide …
Experimental
Matched Name: … D-phenylalanyl-N-(3-fluorobenzyl)-L-prolinamide …
Matched Iupac: … (2S)-1-[(2R)-2-amino-3-phenylpropanoyl]-N-[(3-fluorophenyl)methyl]pyrrolidine-2-carboxamide …
Tifuvirtide is the first members of a new class of anti-HIV drugs which is also called fusion inhibitors. It has received fast-track designation from the FDA and is in Phase I/II clinical testing.
Investigational
Experimental
Matched Synonyms: … β-D-Galp-(1→4)-β-D-Galp ... β-D-galactopyranosyl-(1→4)-β-D-galactopyranose …
Matched Name: … beta-D-galactopyranosyl-(1->4)-beta-D-galactopyranose …
Matched Iupac: … (2R,3R,4R,5R,6R)-6-(hydroxymethyl)-5-{[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy …
As of July 2020, Medicine Invention Design, Inc. is sponsoring a small, controlled clinical trial for the COVID-19 AP TP Vaccine for ‘proof of concept.’ The vaccine utilizes granulocyte macrophage-colony stimulating factor (GM-CSF), a cytokine known to enhance vaccine efficacy through prolongation of humoral and cell immunity.
Investigational
Experimental
Matched Iupac: … 3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-4-methyl-5-[2-(phosphonooxy)ethyl]-1,3-thiazol-3-ium chloride …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
INZ-701 is an enzyme replacement therapy under development with the intention to be used for the treatment of calcification disorders of the circulatory system, bones, and kidneys.
Investigational
Matched Synonyms: … Recombinant human ectonucleotide pyrophosphatase/phosphodiesterase 1 fused to the Fc fragment of IGG1 …
Novolimus is under investigation in clinical trial NCT04483791 (Dynamx Bioadaptor Hong Kong Registry).
Investigational
Experimental
Matched Name: … (4S)-4-(2-NAPHTHYLMETHYL)-D-GLUTAMIC ACID …
Matched Iupac: … (2R,4S)-2-amino-4-[(naphthalen-2-yl)methyl]pentanedioic acid …
Experimental
Matched Synonyms: … 2-(4-hydroxyphenyl)benzo(b)thiophene-6-ol …
Matched Name: … 2-(4-hydroxyphenyl)benzo[b]thiophen-6-ol …
Matched Iupac: … 2-(4-hydroxyphenyl)-1-benzothiophen-6-ol …
Experimental
Matched Name: … 2-(4-CHLORO-PHENYLAMINO)-NICOTINIC ACID …
Matched Iupac: … 2-[(4-chlorophenyl)amino]pyridine-3-carboxylic acid …
Three paclitaxel molecules linked by a cleavable succinyl ester linkage to a brain peptide vector, Angiopep-2, conjugate named ANG1005.
Investigational
Matched Synonyms: … [a-N-(2'succinyl-paclitaxel)Thr]-Phe-Phe-Tyr-Gly-Gly-Ser-Arg-Gly-[epsilon-N-(2'succinyl-paclitaxel)Lys ... ]-Arg-Asn-Asn-Phe-[epsilon-N-(2'succinyl-paclitaxel)Lys]-Thr-Glu-Glu-Tyr …
Matched Description: … paclitaxel molecules linked by a cleavable succinyl ester linkage to a brain peptide vector, Angiopep-2, …
Experimental
Matched Name: … D-phenylalanyl-N-(3-chlorobenzyl)-L-prolinamide …
Matched Iupac: … (2S)-1-[(2R)-2-amino-3-phenylpropanoyl]-N-[(3-chlorophenyl)methyl]pyrrolidine-2-carboxamide …
Displaying drugs 9726 - 9750 of 11213 in total