Displaying drugs 9751 - 9775 of 11267 in total
Tyvelose
Experimental
N-Formylpiperidine
Experimental
Matched Synonyms: … 1-Formylpiperidine ... 1-Piperidinecarboxaldehyde …
Matched Iupac: … piperidine-1-carbaldehyde …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Iupac: … piperidine-1-carbaldehyde …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Dendritic cells vaccine
The recombinant chimeric DC vaccine is a subunit-based vaccine candidate investigated for safety and effectiveness against SARS-CoV-2-induced pneumonia. With a better safety profile than inactivated and live-attenuated virus and virus-vector vaccines, the recombinant chimeric DC vaccine reduces the risk of virulence recovery, pre-existing anti-vector immunity, and incomplete viral inactivation.
As...
Investigational
Matched Description: … vaccine is a subunit-based vaccine candidate investigated for safety and effectiveness against SARS-CoV-2- …
2-Phenylamino-Ethanesulfonic Acid
Experimental
Matched Name: … 2-Phenylamino-Ethanesulfonic Acid …
Matched Iupac: … 2-(phenylamino)ethane-1-sulfonic acid …
Matched Iupac: … 2-(phenylamino)ethane-1-sulfonic acid …
4-(2-AMINOETHYL)BENZENESULFONAMIDE
Experimental
Matched Name: … 4-(2-AMINOETHYL)BENZENESULFONAMIDE …
Matched Iupac: … 4-(2-aminoethyl)benzene-1-sulfonamide …
Matched Iupac: … 4-(2-aminoethyl)benzene-1-sulfonamide …
MK-4965
MK-4965 is an HIV-1 reverse transcriptase inhibitor.
Experimental
Matched Iupac: … 3-[5-({6-amino-1H-pyrazolo[3,4-b]pyridin-3-yl}methoxy)-2-chlorophenoxy]-5-chlorobenzonitrile …
Matched Description: … MK-4965 is an HIV-1 reverse transcriptase inhibitor. …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Description: … MK-4965 is an HIV-1 reverse transcriptase inhibitor. …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Phthalocyanine
Phthalocyanine is under investigation in clinical trial NCT00103246 (Photodynamic Therapy Using Silicon Phthalocyanine 4 in Treating Patients With Actinic Keratosis, Bowen's Disease, Skin Cancer, or Stage I or Stage II Mycosis Fungoides).
Investigational
Matched Iupac: … 2,11,20,29,37,38,39,40-octaazanonacyclo[28.6.1.1³,¹⁰.1¹²,¹⁹.1²¹,²⁸.0⁴,⁹.0¹³,¹⁸.0²²,²⁷.0³¹,³⁶]tetraconta …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Vesencumab
Vesencumab is under investigation in clinical trial NCT00747734 (A Study of MNRP1685A in Patients With Locally Advanced or Metastatic Solid Tumors).
Investigational
Matched Categories: … Neuropilin-1 …
PF-06273340
Pf 06273340 is under investigation in clinical trial NCT01934738 (A Study to Evaluate Safety, Toleration and Time Course of Plasma Concentration of Multiple Oral Doses of PF-06273340 in Healthy Subjects of Two AgeGroups, Aged 18-55 Years (Group 1) and Aged 56-75 Years (Group 2)).
Investigational
Matched Iupac: … N-{5-[2-amino-7-(1-hydroxy-2-methylpropan-2-yl)-7H-pyrrolo[2,3-d]pyrimidine-5-carbonyl]pyridin-3-yl}- ... 2-(5-chloropyridin-2-yl)acetamide …
Matched Description: … and Aged 56-75 Years (Group 2)). ... of Multiple Oral Doses of PF-06273340 in Healthy Subjects of Two AgeGroups, Aged 18-55 Years (Group 1) …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Description: … and Aged 56-75 Years (Group 2)). ... of Multiple Oral Doses of PF-06273340 in Healthy Subjects of Two AgeGroups, Aged 18-55 Years (Group 1) …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
1-Aminocyclopropanecarboxylic Acid
Experimental
Matched Name: … 1-Aminocyclopropanecarboxylic Acid …
Matched Iupac: … 1-aminocyclopropane-1-carboxylic acid …
Matched Iupac: … 1-aminocyclopropane-1-carboxylic acid …
N-(1-adamantyl)-N'-(4-guanidinobenzyl)urea
Experimental
Matched Name: … N-(1-adamantyl)-N'-(4-guanidinobenzyl)urea …
Matched Iupac: … 3-(adamantan-1-yl)-1-({4-[(diaminomethylidene)amino]phenyl}methyl)urea …
Matched Iupac: … 3-(adamantan-1-yl)-1-({4-[(diaminomethylidene)amino]phenyl}methyl)urea …
4-Methylpiperazin-1-Yl Carbonyl Group
Experimental
Matched Name: … 4-Methylpiperazin-1-Yl Carbonyl Group …
Matched Iupac: … 4-methylpiperazine-1-carboxylic acid …
Matched Iupac: … 4-methylpiperazine-1-carboxylic acid …
CX-717
CX-717 is an ampakine compound previously investigated for the treatment of Attention-Deficit/Hyperactivity Disorder (ADHD) and Alzheimer's disease.
Illicit
Investigational
Matched Iupac: … 5-(morpholine-4-carbonyl)-2,1,3-benzoxadiazole …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Lesinidase alfa
Lesinidase alfa is under investigation in clinical trial NCT02324049 (Safety, Pharmacokinetics, and Pharmacodynamics/Efficacy of SBC-103 in Mucopolysaccharidosis III, Type B (MPS IIIB)).
Investigational
Zorubicin
Zorubicin is a drug of the anthracycline class - a class of medications that have historically demonstrated effective chemotherapy for a variety of cancer types.
Experimental
Matched Synonyms: … Benzoic acid hydrazide, 3-hydrazone with daunorubicin …
Matched Iupac: … N'-{1-[(2S,4S)-4-{[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy}-2,5,12-trihydroxy-7-methoxy ... -6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-2-yl]ethylidene}benzohydrazide …
Matched Salts cas: … 36508-71-1 …
Matched Iupac: … N'-{1-[(2S,4S)-4-{[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy}-2,5,12-trihydroxy-7-methoxy ... -6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-2-yl]ethylidene}benzohydrazide …
Matched Salts cas: … 36508-71-1 …
D-Lactic acid
A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
Experimental
Matched Synonyms: … D-2-Hydroxypropanoic acid ... D-2-Hydroxypropionic acid …
Matched Iupac: … (2R)-2-hydroxypropanoic acid …
Matched Iupac: … (2R)-2-hydroxypropanoic acid …
BBIBP-CorV
BBIBP-CorV vaccine contains a SARS-CoV-2 strain inactivated inside Vero Cells. Investigation shows this vaccine induces neutralizing antibodies in several mammalian species while also showing protective efficacy with SARS-CoV-2 challenge in rhesus macaques . As of August 2020, this vaccine is being tested for prophylaxis against COVID-19 in human clinical trials.
Investigational
Matched Synonyms: … Purified inactivated SARS-CoV-2 Vaccine …
Matched Description: … BBIBP-CorV vaccine contains a SARS-CoV-2 strain inactivated inside Vero Cells. ... neutralizing antibodies in several mammalian species while also showing protective efficacy with SARS-CoV-2 …
Matched Description: … BBIBP-CorV vaccine contains a SARS-CoV-2 strain inactivated inside Vero Cells. ... neutralizing antibodies in several mammalian species while also showing protective efficacy with SARS-CoV-2 …
Fluocortolone caproate
Experimental
Matched Iupac: … 4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl]-2-oxoethyl hexanoate ... 2-[(1S,2R,3aS,3bS,5S,9aR,9bS,10S,11aS)-5-fluoro-10-hydroxy-2,9a,11a-trimethyl-7-oxo-1H,2H,3H,3aH,3bH, …
Theralizumab
Theralizumab is a humanized anti-CD28 monoclonal antibody designed for treating autoimmune diseases and cancer. After the first human trial, it was withdrawn due to severe toxicity (likely due to lymphopenia and human cytokine release).[A216527,A216532]
Investigational
Neridronic Acid
Experimental
Investigational
Matched Synonyms: … (6-amino-1-hydroxyhexylidene)diphosphonic acid …
Matched Iupac: … (6-amino-1-hydroxy-1-phosphonohexyl)phosphonic acid …
Matched Iupac: … (6-amino-1-hydroxy-1-phosphonohexyl)phosphonic acid …
Acetorphine
Experimental
Illicit
Matched Synonyms: … 7alpha-etorphine 3-acetate …
Matched Iupac: … (1R,2R,6S,14R,15R,19R)-19-[(2R)-2-hydroxypentan-2-yl]-15-methoxy-3-methyl-13-oxa-3-azahexacyclo[13.2.2.1²,⁸.0¹,⁶.0⁶,¹⁴.0⁷,¹² …
Matched Iupac: … (1R,2R,6S,14R,15R,19R)-19-[(2R)-2-hydroxypentan-2-yl]-15-methoxy-3-methyl-13-oxa-3-azahexacyclo[13.2.2.1²,⁸.0¹,⁶.0⁶,¹⁴.0⁷,¹² …
Decoglurant
Decoglurant has been used in trials studying the treatment of Major Depressive Disorder.
Investigational
Matched Iupac: … 5-{2-[7-(trifluoromethyl)-5-[4-(trifluoromethyl)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]ethynyl}pyridin- ... 2-amine …
Pleconaril
Pleconaril is an antiviral drug from viral capsid inhibitor class, manufactured by Schering-Plough and intended for the prevention of acute asthma exacerbations and common cold symptoms in asthmatic patients who have had exposure to picornavirus. It acts by inhibiting viral replication. The use of pleconaril has not gained approval by...
Investigational
Matched Iupac: … 3-{3,5-dimethyl-4-[3-(3-methyl-1,2-oxazol-5-yl)propoxy]phenyl}-5-(trifluoromethyl)-1,2,4-oxadiazole …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Alovudine
Investigational
Matched Iupac: … 1-[(2R,4S,5R)-4-fluoro-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione …
Displaying drugs 9751 - 9775 of 11267 in total