Displaying drugs 9826 - 9850 of 12591 in total
Omecamtiv Mecarbil
Omecamtiv Mecarbil has been used in trials studying the treatment and basic science of Heart Failure, Echocardiogram, Pharmacokinetics, Chronic Heart Failure, and History of Chronic Heart Failure, among others.
Investigational
Matched Description: … Omecamtiv Mecarbil has been used in trials studying the treatment and basic science of Heart Failure, ... Echocardiogram, Pharmacokinetics, Chronic Heart Failure, and History of Chronic Heart Failure, among …
Ibipinabant
Ibipinabant has been used in trials studying the treatment of Obesity and Obesity and Type 2 Diabetes.
Investigational
Matched Description: … Ibipinabant has been used in trials studying the treatment of Obesity and Obesity and Type 2 Diabetes …
Neosaxitoxin
Neosaxitoxin is under investigation in clinical trial NCT01786655 (Safety Study of Long-Acting Local Anesthetic).
Investigational
Matched Description: … Neosaxitoxin is under investigation in clinical trial NCT01786655 (Safety Study of Long-Acting Local …
Benzamidine
Experimental
5-Amidino-Benzimidazole
Experimental
Indalpine
Indalpine was one of the first selective serotonin reuptake inhibitors to reach the American market. It was initially marketed by Pharmuka. However, after the emergence of widespread concern regarding adverse effects caused by SSRIs, and reported hematological effects caused by Indalpine, it was abruptly withdrawn from the US market.
Investigational
Withdrawn
Matched Description: … Indalpine was one of the first selective serotonin reuptake inhibitors to reach the American market. ... However, after the emergence of widespread concern regarding adverse effects caused by SSRIs, and reported …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Pirlindole
This drug is classified as a reversible inhibitor of monoamine oxidase A enzyme (also known as a RIMA drug). It was developed and is currently used as an antidepressant in Russia. Its chemical structure is similar to metralindole, and it also shares pharmacological properties with this drug.
Pirlindole is a...
Experimental
Matched Description: … supported by many years of clinical experience in the treatment of depression. ... Pirlindole's efficacy and safety have also been shown in the treatment of fibromyalgia. ... This drug is classified as a reversible inhibitor of monoamine oxidase A enzyme (also known as a RIMA …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Chloral betaine
Illicit
Withdrawn
Epofolate
Epofolate has been used in trials studying the treatment of Advanced Solid Tumors. Epofolate (BMS-753493) is a folate conjugate of the epothilone analog BMS-748285 that was designed to selectively target folate receptor expressing cancer cells. In Phase I/IIa pharmacokinetic and safety studies epofolate was generally tolerable and toxicities known to...
Investigational
Matched Iupac: … ethyl}disulfanyl)ethyl]carbamoyl}ethyl]carbamoyl}butyl]carbamoyl}-2-carboxyethyl]carbamoyl}butanoic acid …
Matched Description: … Epofolate has been used in trials studying the treatment of Advanced Solid Tumors. ... Epofolate (BMS-753493) is a folate conjugate of the epothilone analog BMS-748285 that was designed to ... Antitumor activity was not demonstrated and further development of BMS-753493 has been discontinued. …
Matched Description: … Epofolate has been used in trials studying the treatment of Advanced Solid Tumors. ... Epofolate (BMS-753493) is a folate conjugate of the epothilone analog BMS-748285 that was designed to ... Antitumor activity was not demonstrated and further development of BMS-753493 has been discontinued. …
N-[(Aminooxy)Carbonyl]Aniline
Experimental
Mebicar
Experimental
(Rp)-cAMPS
Experimental
Furazolidone
A nitrofuran derivative with antiprotozoal and antibacterial activity. Furazolidone binds bacterial DNA which leads to the gradual inhibition of monoamine oxidase. (From Martindale, The Extra Pharmacopoeia, 30th ed, p514)
Experimental
Vet approved
Matched Description: … Furazolidone binds bacterial DNA which leads to the gradual inhibition of monoamine oxidase. …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
AZD-8330
AZD-8330 is a potent, selective, orally active MEK inhibitor that blocks signal transduction pathways implicated in cancer cell proliferation and survival. AZD-8330 has shown tumor suppressive activity in multiple preclinical models of human cancer including melanoma, pancreatic, colon, lung, and breast cancers.
Investigational
Matched Description: … AZD-8330 has shown tumor suppressive activity in multiple preclinical models of human cancer including …
AZD-1305
AZD1305 has been used in trials studying the treatment and basic science of Atrial Flutter, Atrial Fibrillation, and Left Ventricle Function.
Investigational
Matched Description: … AZD1305 has been used in trials studying the treatment and basic science of Atrial Flutter, Atrial Fibrillation …
Omarigliptin
Omarigliptin has been used in trials studying the treatment of Type 2 Diabetes Mellitus and Chronic Renal Insufficiency.
Investigational
Matched Description: … Omarigliptin has been used in trials studying the treatment of Type 2 Diabetes Mellitus and Chronic Renal …
Bis(5-Amidino-Benzimidazolyl)Methane
Experimental
Diminazene
Diminazene, also known as Diminazine, 4,4'-(Diazoamino)benzamidine, 4,4'-(1-triazene-1,3-diyl)bis-benzenecarboximidamide, diminazine aceturate, or Diminazene aceturate, is a trypanocidal agent. Major brands of Diminazene are Berenil, Pirocide, Ganasag, and Azidin. This substance is a solid. This compound belongs to the phenylhydrazines. These are compounds containing a phenylhydrazide moiety, which consists of a hydrazide substituent...
Experimental
Matched Description: … Major brands of Diminazene are Berenil, Pirocide, Ganasag, and Azidin. This substance is a solid. ... These are compounds containing a phenylhydrazide moiety, which consists of a hydrazide substituent attached ... Known drug targets of diminazene include HTH-type transcriptional regulator QacR, trypsin-1, amiloride-sensitive …
Thieno[2,3-B]Pyridine-2-Carboxamidine
Experimental
4-(METHYLSULFONYL)BENZENECARBOXIMIDAMIDE
Experimental
Hemi-Babim
Experimental
Displaying drugs 9826 - 9850 of 12591 in total