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DB06350InvestigationalSmall molecule
A P2Y12 inhibitor and platelet aggregation inhibitor.
- Mechanism
- Curator reviewed
PRT060128 is a specific, reversible ADP receptor antagonist that binds to the P2Y12 receptor on platelets. PRT06128 prevents binding of adenosine diphosphate (ADP) to its platelet receptor, impairing the ADP-mediated activation of the glycoprotein GPIIb/IIIa complex, a key step in the coagulation cascade. PRT060128 likely has a similar mechanism of action to clopidogrel.
- Primary indication
- Investigated for use/treatment in cardiovascular disorders and myocardial infarction.Curator reviewed
- Formula / weight
- C20H15ClFN5O5S2 · 523.94 g/mol (avg)
- Code names
- PRT-060128
Resolves to
Structure
InChIKey
LGSDFTPAICUONK-UHFFFAOYSA-NSMILESCNC1=C(F)C=C2C(NC(=O)N(C2=O)C2=CC=C(NC(=O)NS(=O)(=O)C3=CC=C(Cl)S3)C=C2)=C1Targets
What you can answer from here — as of September 21, 2026
Which drugs share a target with Elinogrel, and which of those have an active Phase 3 trial?