Displaying drugs 9851 - 9875 of 10794 in total
Tofisopam
Tofisopam (marketed under brand names Emandaxin and Grandaxin) is a 2,3-benzodiazepine drug which is a benzodiazepine derivative. In contrast to classical 1,4-benzodiazepines, the compound does not bind to the benzodiazepine binding site of the gamma-aminobutyric acid receptor and its psychopharmacological profile differs from such compounds. Although Tofisopam is not approved...
Experimental
Matched Iupac: … 1-(3,4-dimethoxyphenyl)-5-ethyl-7,8-dimethoxy-4-methyl-5H-2,3-benzodiazepine …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Arsthinol
Arsthinol (INN) is an antiprotozoal agent that was first synthesized by Ernst A.H. Friedheim in 1949 via the complexing of acetarsol with 2,3-dimercaptopropanol. It has since been demonstrated that the agent possesses activity against amoebas and yaws. Considered well tolerated when compared to other related trivalent organoarsenicals, arsthinol has even...
Experimental
Matched Iupac: … N-{2-hydroxy-5-[4-(hydroxymethyl)-1,3,2-dithiarsolan-2-yl]phenyl}acetamide …
Nifurpirinol
Experimental
Vet approved
Matched Iupac: … {6-[(1E)-2-(5-nitrofuran-2-yl)ethenyl]pyridin-2-yl}methanol …
Aceneuramic acid
Aceneuramic acid has been used in trials studying the treatment of Distal Myopathy, Nonaka Type, Hereditary Inclusion Body Myopathy, and Distal Myopathy With Rimmed Vacuoles.
Investigational
Matched Iupac: … (4S,5R,6R,7S,8R)-5-acetamido-4,6,7,8,9-pentahydroxy-2-oxononanoic acid …
Briciclib
Briciclib has been used in trials studying the treatment of Lymphoma, Neoplasms, Advanced Solid Tumor, and Acute Lymphocytic Leukemia.
Investigational
Matched Iupac: … (2-methoxy-5-{[(E)-2-(2,4,6-trimethoxyphenyl)ethenesulfonyl]methyl}phenoxy)phosphonic acid …
Piribedil
Piribedil has been investigated in Parkinson's Disease.
Investigational
Matched Iupac: … 2-{4-[(2H-1,3-benzodioxol-5-yl)methyl]piperazin-1-yl}pyrimidine …
Olumacostat glasaretil
Olumacostat glasaretil has been used in trials studying the treatment of Acne Vulgaris.
Investigational
Matched Iupac: … ethyl 2-{N-methyl-2-[5-(tetradecyloxy)furan-2-carbonyloxy]acetamido}acetate …
Menglytate
Experimental
Matched Iupac: … (1R,2S,5R)-5-methyl-2-(propan-2-yl)cyclohexyl 2-ethoxyacetate …
N-cycloheptylglycyl-N-(4-carbamimidoylbenzyl)-L-prolinamide
Experimental
Matched Name: … N-cycloheptylglycyl-N-(4-carbamimidoylbenzyl)-L-prolinamide …
Matched Iupac: … (2S)-N-[(4-carbamimidoylphenyl)methyl]-1-[2-(cycloheptylamino)acetyl]pyrrolidine-2-carboxamide …
Matched Iupac: … (2S)-N-[(4-carbamimidoylphenyl)methyl]-1-[2-(cycloheptylamino)acetyl]pyrrolidine-2-carboxamide …
9-(2-Deoxy-Beta-D-Ribofuranosyl)-6-Methylpurine
Experimental
Matched Name: … 9-(2-Deoxy-Beta-D-Ribofuranosyl)-6-Methylpurine …
Matched Iupac: … (2R,3S,5R)-2-(hydroxymethyl)-5-(6-methyl-9H-purin-9-yl)oxolan-3-ol …
Matched Iupac: … (2R,3S,5R)-2-(hydroxymethyl)-5-(6-methyl-9H-purin-9-yl)oxolan-3-ol …
Sitafloxacin
Experimental
Investigational
Matched Iupac: … bis(7-[(7S)-7-amino-5-azaspiro[2.4]heptan-5-yl]-8-chloro-6-fluoro-1-[(1R,2S)-2-fluorocyclopropyl]-4-oxo ... -1,4-dihydroquinoline-3-carboxylic acid) trihydrate …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Amcasertib
Amcasertib is under investigation in clinical trial NCT02483247 (A Study of BBI503 in Combination With Selected Anti-Cancer Therapeutics in Adult Patients With Advanced Cancer).
Investigational
Matched Iupac: … N-[2-(diethylamino)ethyl]-2,4-dimethyl-5-{[(3Z)-2-oxo-5-(2-phenyl-1,3-thiazol-4-yl)-2,3-dihydro-1H-indol ... -3-ylidene]methyl}-1H-pyrrole-3-carboxamide …
Elenbecestat
Elenbecestat is under investigation in clinical trial NCT02956486 (A 24-Month Study to Evaluate the Efficacy and Safety of Elenbecestat (E2609) in Subjects With Early Alzheimer's Disease).
Investigational
Matched Iupac: … N-{3-[(4aS,5R,7aS)-2-amino-5-methyl-4H,4aH,5H,7H,7aH-furo[3,4-d][1,3]thiazin-7a-yl]-4-fluorophenyl}-5 ... -(difluoromethyl)pyrazine-2-carboxamide …
Praliciguat
Praliciguat is under investigation in clinical trial NCT03254485 (A Study of the Effect of IW-1973 on the Exercise Capacity of Patients With Heart Failure With Preserved Ejection Fraction (Hfpef)).
Investigational
Matched Iupac: … 1,1,1-trifluoro-3-[(5-fluoro-2-{1-[(2-fluorophenyl)methyl]-5-(1,2-oxazol-3-yl)-1H-pyrazol-3-yl}pyrimidin ... -4-yl)amino]-2-(trifluoromethyl)propan-2-ol …
Famitinib
Famitinib has been used in trials studying the treatment of Colorectal Cancer, Renal Cell Cancer, Colorectal Cancer Recurrent, Colorectal Cancer Metastatic, and Metastatic Renal Cell Cancer, among others.
Investigational
Matched Iupac: … (3Z)-3-({5-[2-(diethylamino)ethyl]-3-methyl-4-oxo-1H,4H,5H,6H,7H-pyrrolo[3,2-c]pyridin-2-yl}methylidene ... )-5-fluoro-2,3-dihydro-1H-indol-2-one …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Lifirafenib
Lifirafenib is under investigation in clinical trial NCT03641586 (The Study of BGB-283 in Chinese Subjects With Local Advanced or Metastatic Malignant Solid Tumor).
Investigational
Matched Iupac: … 5-{[(2R,3R,4S)-3-[6-(trifluoromethyl)-1H-1,3-benzodiazol-2-yl]-5-oxatricyclo[4.4.0.0^{2,4}]deca-1(6), ... 7,9-trien-9-yl]oxy}-1,2,3,4-tetrahydro-1,8-naphthyridin-2-one …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
TOP-1288
TOP-1288 is under investigation in clinical trial NCT02888379 (Phase 2a Study to Evaluate the Safety/Tolerability and Efficacy of TOP1288 200 mg Rectal Solution Once Daily for 4 Weeks in Ulcerative Colitis).
Investigational
Matched Iupac: … 3-({4-[(4-{[(5-tert-butyl-3-methanesulfonamido-2-methoxyphenyl)carbamoyl]amino}naphthalen-1-yl)oxy]pyrimidin ... -2-yl}amino)-5-ethynyl-N-{2-[2-(2-methoxyethoxy)ethoxy]ethyl}benzamide …
Matched Description: … Study to Evaluate the Safety/Tolerability and Efficacy of TOP1288 200 mg Rectal Solution Once Daily for 4 …
Matched Description: … Study to Evaluate the Safety/Tolerability and Efficacy of TOP1288 200 mg Rectal Solution Once Daily for 4 …
Rusfertide
Rusfertide is a hepcidin mimetic currently being developed by Protagonist Therapeutics for the treatment of polycythemia vera and beta-thalassemia.
Investigational
L-1-naphthyl-2-acetamido-ethane boronic acid
Experimental
Matched Name: … L-1-naphthyl-2-acetamido-ethane boronic acid …
Matched Iupac: … [(1R)-1-acetamido-2-(naphthalen-1-yl)ethyl]trihydroxyboranuide …
Matched Iupac: … [(1R)-1-acetamido-2-(naphthalen-1-yl)ethyl]trihydroxyboranuide …
D-1-naphthyl-2-acetamido-ethane boronic acid
Experimental
Matched Name: … D-1-naphthyl-2-acetamido-ethane boronic acid …
Matched Iupac: … trihydroxy[(1S)-1-[(1-hydroxyethylidene)amino]-2-(naphthalen-1-yl)ethyl]boranuide …
Matched Iupac: … trihydroxy[(1S)-1-[(1-hydroxyethylidene)amino]-2-(naphthalen-1-yl)ethyl]boranuide …
[2(Formyl-Hydroxy-Amino)-Ethyl]-Phosphonic Acid
Experimental
Matched Name: … [2(Formyl-Hydroxy-Amino)-Ethyl]-Phosphonic Acid …
Matched Iupac: … [2-(N-hydroxyformamido)ethyl]phosphonic acid …
Matched Iupac: … [2-(N-hydroxyformamido)ethyl]phosphonic acid …
trifluoro-[hydroxy-[hydroxy-[2-(N-methyl-2-nitro-anilino)ethoxy]phosphoryl]oxy-phosphoryl]oxy-beryllium(1-)
Experimental
Matched Name: … trifluoro-[hydroxy-[hydroxy-[2-(N-methyl-2-nitro-anilino)ethoxy]phosphoryl]oxy-phosphoryl]oxy-beryllium …
Matched Iupac: … ({hydroxy[(trifluoroberylliuide)oxy]phosphoryl}oxy)({2-[methyl(2-nitrophenyl)amino]ethoxy})phosphinic …
Matched Iupac: … ({hydroxy[(trifluoroberylliuide)oxy]phosphoryl}oxy)({2-[methyl(2-nitrophenyl)amino]ethoxy})phosphinic …
Anacetrapib
Investigational
Matched Iupac: … (4S,5R)-5-[3,5-bis(trifluoromethyl)phenyl]-3-{[4'-fluoro-2'-methoxy-5'-(propan-2-yl)-4-(trifluoromethyl ... )-[1,1'-biphenyl]-2-yl]methyl}-4-methyl-1,3-oxazolidin-2-one …
Crinecerfont
Investigational
Matched Iupac: … 4-(2-chloro-4-methoxy-5-methylphenyl)-N-[(1S)-2-cyclopropyl-1-(3-fluoro-4-methylphenyl)ethyl]-5-methyl-N ... -(prop-2-yn-1-yl)-1,3-thiazol-2-amine …
Displaying drugs 9851 - 9875 of 10794 in total