Displaying drugs 76 - 100 of 325 in total
Lonafarnib
Hutchinson-Gilford progeria syndrome (HGPS) is a rare autosomal dominant disorder estimated to affect approximately one in 20 million individuals resulting in adverse symptoms associated with premature ageing: skeletal dysplasia, joint contractures, atherosclerosis, myocardial fibrosis/dysfunction, scleroderma-like cutaneous effects, lipoatrophy, alopecia, and a severe failure to thrive; HGPS is uniformly fatal.[A224379, A224384,...
Approved
Investigational
Bedaquiline
Bedaquiline is a bactericidal antimycobacterial drug belonging to the class of diarylquinoline. The quinolinic central heterocyclic nucleus with alcohol and amine side chains is responsible for bedaquiline-mediated antimycobacterial activity. Although it is closely related to fluoroquinolones, bedaquiline does not affect DNA gyrase; instead, bedaquiline inhibits the c subunit of ATP...
Approved
Benzalkonium
Benzalkonium is a quaternary ammonium compound used as a biocide, a cationic surfactant, and as a phase transfer agent [FDA Label]. Benzalkonium is more commonly contained in consumer products in its salt form, benzalkonium chloride [FDA Label]. This salt is used in a great variety of international pharmaceutical products such...
Approved
Investigational
Matched Salts name: … Benzalkonium bromide …
Binimetinib
Binimetinib, also known as Mektovi, is a potent and selective oral mitogen-activated protein kinase 1/2 (MEK 1/2) inhibitor which is combined with Encorafenib.[A34275,L3335]
On June 27, 2018, the Food and Drug Administration approved the combination of Encorafenib and binimetinib (BRAFTOVI and MEKTOVI, from Array BioPharma Inc.) in combination for patients...
Approved
Investigational
Dequalinium
Dequalinium is an antibacterial agent with multi-targeted actions. It also possesses antifungal, antiparasitic, antiviral, anticancer, and neuroprotective properties. It is a quaternary ammonium compound, as it consists of an amphipathic cation with two aminoquinaldinium rings at both ends of a long hydrophobic hydrocarbon chain. Due to its flexible structure, dequalinium...
Approved
Investigational
Matched Salts name: … Dequalinium bromide …
Azoximer bromide
Azoximer bromide is under investigation in clinical trial NCT04381377 (Efficacy and Safety of Polyoxidonium® in Hospitalized Patients With Coronavirus Disease COVID-19).
Investigational
Matched Synonyms: … Azoximer bromide ... Poly((1-(carboxymethyl)piperazin-1-ium-1,4-diyl bromide)ethylene-co-((piperazin-1,4-diyl 1-oxide)ethylene …
Matched Name: … Azoximer bromide …
Matched Description: … Azoximer bromide is under investigation in clinical trial NCT04381377 (Efficacy and Safety of Polyoxidonium …
Matched Name: … Azoximer bromide …
Matched Description: … Azoximer bromide is under investigation in clinical trial NCT04381377 (Efficacy and Safety of Polyoxidonium …
Radium Ra-223
Radium 223 is under investigation in clinical trial NCT02463799 (Ph 2 Study of Sipuleucel-T W/ or W/O Radium-223 in Men With Asymptomatic or Minimally Symptomatic Bone-MCRPC).
Investigational
Matched Synonyms: … Radium-223 …
Matched Name: … Radium Ra-223 …
Matched Iupac: … (223Ra)radium …
Matched Description: … Radium-223 in Men With Asymptomatic or Minimally Symptomatic Bone-MCRPC). ... Radium 223 is under investigation in clinical trial NCT02463799 (Ph 2 Study of Sipuleucel-T W/ or W/O …
Matched Name: … Radium Ra-223 …
Matched Iupac: … (223Ra)radium …
Matched Description: … Radium-223 in Men With Asymptomatic or Minimally Symptomatic Bone-MCRPC). ... Radium 223 is under investigation in clinical trial NCT02463799 (Ph 2 Study of Sipuleucel-T W/ or W/O …
Fazadinium bromide
Experimental
Matched Synonyms: … Fazadinium bromide …
Matched Name: … Fazadinium bromide …
Matched Categories: … fazadinium bromide …
Matched Name: … Fazadinium bromide …
Matched Categories: … fazadinium bromide …
Ciclonium bromide
Experimental
Matched Synonyms: … Ciclonium bromide ... Cyclonium bromide …
Matched Name: … Ciclonium bromide …
Matched Iupac: … [2-(1-{bicyclo[2.2.1]hept-5-en-2-yl}-1-phenylethoxy)ethyl]diethylmethylazanium bromide …
Matched Name: … Ciclonium bromide …
Matched Iupac: … [2-(1-{bicyclo[2.2.1]hept-5-en-2-yl}-1-phenylethoxy)ethyl]diethylmethylazanium bromide …
Radium Ra-223 cation
Experimental
Matched Synonyms: … Radium-223 ion(2+) ... Radium, isotope of mass 223 (223Ra2+) …
Matched Name: … Radium Ra-223 cation …
Matched Iupac: … (223Ra)radium(2+) ion …
Matched Name: … Radium Ra-223 cation …
Matched Iupac: … (223Ra)radium(2+) ion …
Perflubron
Perflubron (Oxygent) is being developed as an intravascular oxygen carrier designed to augment oxygen delivery in surgical patients.
Investigational
Matched Synonyms: … Perfluorooctyl-bromide …
JBI-802
Investigational
Matched Synonyms: … N-hydroxy-4-((4-((((1R,2S)-2-phenylcyclopropyl) amino)methyl)-1H-pyrazol-1-yl)methyl)benzamide hydrogen bromide …
Hexatantalum Dodecabromide
Experimental
Matched Iupac: … tantalum(1+) undecahydrobromide pentatantalum bromide …
Bibenzonium
Experimental
Matched Salts name: … Bibenzonium bromide …
Matched Categories: … bibenzonium bromide …
Matched Categories: … bibenzonium bromide …
16-Bromoepiandrosterone
16-Bromoepiandrosterone is an injectable formulation of a compound called alpha-epi-bromide. It is a chemical relative of DHEA which was selected for development after it showed antiretroviral activity in laboratory tests.
Investigational
Matched Description: … 16-Bromoepiandrosterone is an injectable formulation of a compound called alpha-epi-bromide. …
Leuvectin
Leuvectin (formerly known as VCL-1102) is a component of gene therapy along with cationic lipid 1,2-dimyristyloxypropyl-3-dimethyl-hydroxyethyl ammonium bromide/dioleyl-phosphatidyl-ethanolamine (DMRIE/DOPE).
Investigational
Matched Description: … of gene therapy along with cationic lipid 1,2-dimyristyloxypropyl-3-dimethyl-hydroxyethyl ammonium bromide …
Timepidium
Experimental
Matched Salts name: … Timepidium bromide …
Matched Categories: … timepidium bromide …
Matched Categories: … timepidium bromide …
Thienylfentanyl
Thienylfentanyl is a fentanyl analog analgesic that was sold on the black market in the 1980s until the Federal Analog Act scheduled drugs based on structural similarity rather than scheduling drugs individually. Thienylfentanyl has a similar synthesis pathway to fentanyl except 2-(2-bromoethyl)thiophene is substituted for phenethyl bromide.
Illicit
Matched Description: … similar synthesis pathway to fentanyl except 2-(2-bromoethyl)thiophene is substituted for phenethyl bromide …
Otilonium
Experimental
Investigational
Matched Salts name: … Otilonium bromide …
Matched Categories: … otilonium bromide ... otilonium bromide and psycholeptics …
Matched Categories: … otilonium bromide ... otilonium bromide and psycholeptics …
Prifinium
Prifinium is an antimuscarinic agent with antispasmodic and antiemetic properties. It may be useful for the treatment of irritable bowel syndrome .
Experimental
Matched Salts name: … Prifinium bromide …
Matched Categories: … prifinium bromide …
Matched Categories: … prifinium bromide …
Codeine methylbromide
Experimental
Illicit
Matched Iupac: … dimethyl-12-oxa-4-azapentacyclo[9.6.1.0^{1,13}.0^{5,17}.0^{7,18}]octadeca-7(18),8,10,15-tetraen-4-ium bromide …
Distigmine
Distigmine is a parasympathomimetic agent with a longer duration of action and enhanced drug accumulation compared to DB00545 and DB01400. It is an anticholinergic drug and long-acting reversible carbamate cholinesterase inhibitor that binds directly and competitively to the agonist binding sites of muscurinic receptors. Distigmine is available in several countries...
Experimental
Matched Description: … underactive detrusor and voiding dysfunction in the urinary tract where the active ingredient is distigmine bromide …
Matched Salts name: … Distigmine bromide …
Matched Salts name: … Distigmine bromide …
Bromoform
Experimental
Aniline
Aniline, phenylamine or aminobenzene is an organic compound with the formula C6H5NH2. Consisting of an amine attached to a benzene ring, aniline is the prototypical aromatic amine. Being a precursor to many industrial chemicals, its main use is in the manufacture of precursors to polyurethane. Like most volatile amines, it...
Experimental
Displaying drugs 76 - 100 of 325 in total