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Displaying drugs 976 - 1000 of 3873 in total
Pioglitazone is an antihyperglycemic used as an adjunct to diet, exercise, and other antidiabetic medications to manage type 2 diabetes mellitus.[L11416,L11419,L11422,L11425] It is administered as a racemic mixture, though there is no pharmacologic difference between the enantiomers and they appear to interconvert in vivo with little consequence. The thiazolidinedione class...
Approved
Investigational
Matched Description: … [A19759] Thiazolidinediones, including pioglitazone, have fallen out of favor in recent years due ... Pioglitazone is an antihyperglycemic used as an adjunct to diet, exercise, and other antidiabetic medications ... , bladder cancer) and the availability of safer and more effective alternatives for patients with type …
Matched Mixtures name: … PIOGLITAZONE E METFORMINA DOC ... Pioglitazone Hydrochloride and Metformin Hydrochloride ... Pioglitazone Hydrochloride and Metformin Hydrochloride
Matched Salts name: … Pioglitazone hydrochloride
Matched Categories: … Alimentary Tract and Metabolism ... pioglitazone and alogliptin ... metformin and pioglitazone ... glimepiride and pioglitazone ... pioglitazone and sitagliptin …
Matched Products: … Pioglitazone Hydrochloride ... PIOGLITAZONE HYDROCHLORIDE ... MOPRO-D
Experimental
Matched Synonyms: … Carballylic acid ... 3-carboxyglutaric acid ... β-carboxyglutaric acid
Matched Name: … Tricarballylic acid
Matched Iupac: … propane-1,2,3-tricarboxylic acid
Matched Categories: … Acids, Acyclic ... Carboxylic Acids
An orally administered anthracycline antineoplastic. The compound has shown activity against breast cancer, lymphomas and leukemias, together with the potential for reduced cardiac toxicity.
Approved
Matched Description: … The compound has shown activity against breast cancer, lymphomas and leukemias, together with the potential …
Matched Salts name: … Idarubicin hydrochloride
Matched Categories: … Anthracyclines and Related Substances ... Antineoplastic and Immunomodulating Agents ... Cytotoxic Antibiotics and Related Substances …
Matched Products: … Idarubicin Hydrochloride ... Idarubicin Hydrochloride Injection …
Sotalol is a methanesulfonanilide developed in 1960. It was the first of the class III anti arrhythmic drugs. Sotalol was first approved as an oral tablet on 30 October 1992. A racemic mixture of sotalol is currently formulated as a tablet, oral solution, and intravenous injection indicated for life threatening...
Approved
Matched Description: … [L6334] A racemic mixture of sotalol is currently formulated as a tablet, oral solution, and intravenous ... injection indicated for life threatening ventricular arrhythmias and maintaining normal sinus rhythm …
Matched Salts name: … Sotalol hydrochloride
Matched Categories: … sotalol and acetylsalicylic acid ... Medications that reduce magnesium levels ... Beta Blocking Agents and Thiazides ... Beta Blocking Agents, Non-Selective, and Thiazides ... sotalol and thiazides …
Matched Products: … Dom-sotalol ... Sotalol Hydrochloride ... Sotalol hydrochloride
Experimental
Matched Name: … Ferricrocin-iron
Matched Iupac: … oxidaniumylideneethyl)amino]propyl})-15-(hydroxymethyl)-1,4,7,10,13,16-hexaazacyclooctadecane-2,5,8,11,14,17-hexone iron
A α,β-unsaturated monocarboxylic acid that is ethene substituted by a carboxy group.
Experimental
Matched Synonyms: … acroleic acid ... 2-Propenoic acid ... Propenoic acid
Matched Name: … Acrylic Acid
Matched Iupac: … prop-2-enoic acid
Matched Description: … A α,β-unsaturated monocarboxylic acid that is ethene substituted by a carboxy group. …
Matched Categories: … Equipment and Supplies ... Acids, Acyclic ... Carboxylic Acids
Colesevelam is a bile acid sequestrant. Colesevelam is used with exercise and diet changes (restriction of cholesterol and fat intake) to reduce the amount of cholesterol and certain fatty substances in the blood. It works by binding bile acids in the intestine. Bile acids are made when cholesterol is broken...
Approved
Matched Description: … Colesevelam is used with exercise and diet changes (restriction of cholesterol and fat intake) to reduce ... the amount of cholesterol and certain fatty substances in the blood. ... Colesevelam is a bile acid sequestrant. …
Matched Salts name: … Colesevelam hydrochloride
Matched Categories: … Bile Acid Sequestrants ... Bile-acid Binding Activity …
Matched Products: … Colesevelam Hydrochloride ... Colesevelam hydrochloride
The decarboxylation product of UDPglucuronic acid, which is used for formation of the xylosides of seryl hydroxyl groups in mucoprotein synthesis. Also forms plant xylans.
Experimental
Matched Name: … UDP-alpha-D-xylose …
Matched Iupac: … dihydroxyoxolan-2-yl]methoxy}({[hydroxy({[(2R,3R,4S,5R)-3,4,5-trihydroxyoxan-2-yl]oxy})phosphoryl]oxy})phosphinic acid
Matched Description: … The decarboxylation product of UDPglucuronic acid, which is used for formation of the xylosides of seryl …
Experimental
Matched Name: … Methyl alpha-D-mannoside …
Experimental
Matched Name: … Dodecyl-Alpha-D-Maltoside …
Estradiol acetate is a pro-drug ester of DB00783, a naturally occurring hormone that circulates endogenously within the human body. Estradiol is the most potent form of all mammalian estrogenic steroids and acts as the major female sex hormone. As a pro-drug of estradiol, estradiol acetate therefore has the same downstream...
Approved
Investigational
Vet approved
Matched Synonyms: … Estradiol acetate ... Estradiol 3-acetate ... Estradiol-3-acetate
Matched Name: … Estradiol acetate
Matched Iupac: … 9bS,11aS)-1-hydroxy-11a-methyl-1H,2H,3H,3aH,3bH,4H,5H,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-7-yl acetate
Matched Description: … to severe vasomotor symptoms and vulvovaginal atrophy due to menopause. ... Administration of synthetic and bioidentical forms of estrogen, such as estradiol acetate, has shown ... Estradiol is the most potent form of all mammalian estrogenic steroids and acts as the major female sex …
Experimental
Matched Synonyms: … 1-ethanesulfonic acid ... 2-ethanesulfonic acid ... Ethylsulfonic acid
Matched Name: … Ethanesulfonic acid
Matched Iupac: … ethanesulfonic acid
Matched Categories: … Sulfur Acids ... Sulfonic Acids ... Alkanesulfonic Acids
A common saturated fatty acid found in fats and waxes including olive oil, palm oil, and body lipids.
Approved
Matched Synonyms: … 1-hexyldecanoic acid ... Hexadecoic acid ... Palmitic Acid
Matched Name: … Palmitic Acid
Matched Iupac: … hexadecanoic acid
Matched Description: … A common saturated fatty acid found in fats and waxes including olive oil, palm oil, and body lipids. …
Matched Salts name: … 16-chloropalmitic acid
Matched Categories: … Fatty Acids ... Palmitic Acids
Experimental
Matched Synonyms: … Tosic acid ... Tosylic acid ... 4-toluenesulfonic acid
Matched Name: … p-Toluenesulfonic acid
Matched Iupac: … 4-methylbenzene-1-sulfonic acid
Matched Categories: … Sulfur Acids ... Arylsulfonic Acids ... Sulfonic Acids
N4-Hydroxyctidine, or EIDD-1931, is a ribonucleoside analog which induces mutations in RNA virions.[A193008,A193011] N4-hydroxycytidine was first described in the literature in 1980 as a potent mutagen of bacteria and phage. It has shown antiviral activity against Venezuelan equine encephalitis virus, and the human coronavirus HCoV-NL63 in vitro. N4-hydroxycytodine has been...
Experimental
Matched Synonyms: … Uridine, 4-oxime ... β-D-N4-hydroxycytidine ... beta-D-N-4-Hydroxycytidine …
Matched Description: … in mice and human airway epithelial cells. ... A193011] N4-hydroxycytidine was first described in the literature in 1980 as a potent mutagen of bacteria and ... [A193023] It has shown antiviral activity against Venezuelan equine encephalitis virus,[A193008] and
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Oxyphenisatin acetate is the pro-drug of oxyphenisatin (3,3-bis(4-hydroxyphenyl)-1H-indol-2-one). The FDA withdrew its approval for the use of oxyphenisatin acetate due to safety reasons.
Approved
Investigational
Withdrawn
Matched Synonyms: … Oxyphenisatin acetate ... Oxyphenisatine acetate
Matched Name: … Oxyphenisatin acetate
Matched Iupac: … 4-{3-[4-(acetyloxy)phenyl]-2-oxo-2,3-dihydro-1H-indol-3-yl}phenyl acetate
Matched Description: … The FDA withdrew its approval for the use of oxyphenisatin acetate due to safety reasons.[L43942] ... Oxyphenisatin acetate is the pro-drug of [oxyphenisatin] (3,3-bis(4-hydroxyphenyl)-1H-indol-2-one). …
Experimental
Matched Synonyms: … 2,2,2-trifluoroethyl acetate ... 2,2,2-trifluoroethanol acetate
Matched Name: … Trifluoroethyl acetate
Matched Iupac: … 2,2,2-trifluoroethyl acetate
An anti-androgen that, in the form of its acetate (cyproterone acetate), also has progestational properties. It is used in the treatment of hypersexuality in males, as a palliative in prostatic carcinoma, and, in combination with estrogen, for the therapy of severe acne and hirsutism in females.
Approved
Investigational
Matched Synonyms: … Cyproterone acetate ... Cyproterone 17-O-acetate
Matched Name: … Cyproterone acetate
Matched Iupac: … acetyl-9-chloro-2,16-dimethyl-6-oxopentacyclo[9.7.0.0^{2,8}.0^{3,5}.0^{12,16}]octadeca-7,9-dien-15-yl acetate
Matched Description: … It is used in the treatment of hypersexuality in males, as a palliative in prostatic carcinoma, and, ... in combination with estrogen, for the therapy of severe acne and hirsutism in females. ... An anti-androgen that, in the form of its acetate (cyproterone acetate), also has progestational properties …
Matched Mixtures name: … CIPROTERONA ACETATO 2 MG + ETINILESTRADIOL 0.035 MG. …
Matched Categories: … Antiandrogens and Estrogens ... Combination Contraceptives (with Estrogen and derivatives) ... Genito Urinary System and Sex Hormones ... cyproterone and estrogen ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Andro - Diane 10 mg - Tabletten ... CIPROTERONE ACETATO BAYER ... CIPROTERONA ACETATO 50 MG TABLETAS …
Approved
Matched Synonyms: … Undecoylium chloride-iodine
Matched Name: … Undecoylium chloride iodine complex …
Girentuximab I-124 is under investigation in clinical trial NCT01762592 (REDECT 2: REnal Masses: Pivotal Trial to DEteCT Clear Cell Renal Cell Carcinoma With PET/CT).
Investigational
Matched Synonyms: … IODINE (124I) GIRENTUXIMAB …
Experimental
Matched Synonyms: … d-Dethiobiotin ... (4R-cis)-5-methyl-2-oxo-4-imidazolidinehexanoic acid ... (4R,5S)-5-methyl-2-oxo-4-imidazolidinehexanoic acid
Matched Iupac: … 6-[(4R,5S)-5-methyl-2-oxoimidazolidin-4-yl]hexanoic acid
Matched Categories: … Enzymes and Coenzymes …
A potent calcium channel blockader with marked vasodilator action. It has antihypertensive properties and is effective in the treatment of angina and coronary spasms without showing cardiodepressant effects. It has also been used in the treatment of asthma and enhances the action of specific antineoplastic agents. [PubChem]
Approved
Investigational
Matched Description: … It has antihypertensive properties and is effective in the treatment of angina and coronary spasms without ... It has also been used in the treatment of asthma and enhances the action of specific antineoplastic agents …
Matched Salts name: … Nicardipine Hydrochloride
Matched Categories: … Calcium-Regulating Hormones and Agents ... Adrenergic alpha-Antagonists ... Adrenergic alpha-1 Receptor Antagonists …
Matched Products: … Nicardipine Hydrochloride ... NICARDIPINE HYDROCHLORIDE
Decanoic acid is a solid. This compound belongs to the straight chain fatty acids. These are fatty acids with a straight aliphatic chain. The proteins that decanoic acid targets include furin, octanoyltransferase, 3-oxoacyl-[acyl-carrier-protein] synthase 1, peptostreptococcal albumin-binding protein, and putative uncharacterized protein tcp14.
Experimental
Matched Synonyms: … Capric acid ... Decanoic acid ... n-capric acid
Matched Name: … Capric acid
Matched Iupac: … decanoic acid
Matched Description: … ] synthase 1, peptostreptococcal albumin-binding protein, and putative uncharacterized protein tcp14. ... Decanoic acid is a solid. This compound belongs to the straight chain fatty acids. ... These are fatty acids with a straight aliphatic chain. …
Matched Categories: … Fatty Acids
Experimental
Matched Synonyms: … alpha-abequopyranose ... 3,6-dideoxy-α-D-xylo-hexopyranose …
Esmolol, commonly marketed under the trade name Brevibloc, is a cardioselective beta-1 receptor blocker. It has a rapid onset but short duration of action without causing significant intrinsic sympathomimetic or membrane stabilizing activities at recommended therapeutic doses. It works by blocking beta-adrenergic receptors in the heart, which leads to decreased...
Approved
Withdrawn
Matched Synonyms: … 3-[4-(2-Hydroxy-3-isopropylamino-propoxy)-phenyl]-propionic acid methyl ester …
Matched Description: … It works by blocking beta-adrenergic receptors in the heart, which leads to decreased force and rate ... Esmolol prevents the action of two naturally occurring substances: epinephrine and norepinephrine. ... FDA withdrew its approval for the use of all parenteral dosage form drug products containing esmolol hydrochloride
Matched Salts name: … Esmolol hydrochloride
Matched Products: … Esmolol Hydrochloride ... Esmolol Hydrochloride in Water ... Esmolol Hydrochloride In Sodium Chloride …
Displaying drugs 976 - 1000 of 3873 in total