Displaying drugs 976 - 1000 of 1311 in total
Retifanlimab
Retifanlimab is a humanized IgG4 kappa monoclonal antibody that binds to the programmed death receptor-1 (PD-1), blocking PD-1 interaction with its ligands, programmed death-ligand 1 (PD-L1) and programmed death-ligand 2 (PD-L2). By blocking the PD-1/PD-L1/2 pathway, retifanlimab potentiates T-cell activity and boosts the immune response against cancer cells. Other monoclonal...
Approved
Investigational
Matched Synonyms: … Anti-PD-1 monoclonal antibody MGA012 …
Matched Description: … -1 (PD-1), blocking PD-1 interaction with its ligands, programmed death-ligand 1 (PD-L1) and programmed ... By blocking the PD-1/PD-L1/2 pathway, retifanlimab potentiates T-cell activity and boosts the immune ... [L45603] Other monoclonal antibodies that block PD-1 include [pembrolizumab], [nivolumab] and [cemiplimab …
Matched Categories: … MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Programmed Death Receptor-1 Blocking Antibody …
Matched Description: … -1 (PD-1), blocking PD-1 interaction with its ligands, programmed death-ligand 1 (PD-L1) and programmed ... By blocking the PD-1/PD-L1/2 pathway, retifanlimab potentiates T-cell activity and boosts the immune ... [L45603] Other monoclonal antibodies that block PD-1 include [pembrolizumab], [nivolumab] and [cemiplimab …
Matched Categories: … MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Programmed Death Receptor-1 Blocking Antibody …
Ephedrine
Ephedrine was first described in western literature in 1888, as a naturally occurring component of the ephedra plant, along with pseudoephedrine. Ephedrine acts as both a direct and indirect sympathomimetic. It is an alpha- and beta-adrenergic receptor agonist; however, it also causes the indirect release of norepinephrine from sympathetic neurons,...
Approved
Matched Description: … [A193698] Ephedrine acts as both a direct and indirect sympathomimetic. ... It is an alpha- and beta-adrenergic receptor agonist; however, it also causes the indirect release of ... [A193650,L12972] Ephedrine is used for its vasoconstrictive, positive chronotropic, and positive inotropic …
Matched Categories: … Adrenergic and Dopaminergic Agents ... Alimentary Tract and Metabolism ... Alpha-and Beta-adrenergic Agonists ... Epinephrine and similars ... Herbs and Natural Products …
Matched Products: … HanPoong Gal Cheon Xin Extract Granules …
Matched Categories: … Adrenergic and Dopaminergic Agents ... Alimentary Tract and Metabolism ... Alpha-and Beta-adrenergic Agonists ... Epinephrine and similars ... Herbs and Natural Products …
Matched Products: … HanPoong Gal Cheon Xin Extract Granules …
diethyl [(1R)-1,5-diaminopentyl]boronate
Experimental
Matched Name: … diethyl [(1R)-1,5-diaminopentyl]boronate …
Matched Iupac: … diethyl [(1R)-1,5-diaminopentyl]boronate …
Matched Iupac: … diethyl [(1R)-1,5-diaminopentyl]boronate …
Micafungin
Micafungin is an antifungal drug. It belongs to the antifungal class of compounds known as echinocandins and exerts its effect by inhibiting the synthesis of 1,3-beta-D-glucan, an integral component of the fungal cell wall.
Approved
Investigational
Matched Description: … It belongs to the antifungal class of compounds known as echinocandins and exerts its effect by inhibiting …
Matched Salts name: … Micafungin sodium …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … Micafungin in Sodium Chloride ... Micafungin Sodium for Injection …
Matched Salts name: … Micafungin sodium …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … Micafungin in Sodium Chloride ... Micafungin Sodium for Injection …
Stypocaulon scoparium
Stypocaulon scoparium is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Synonyms: … Halopteris Scoparia Extract ... Sphacelaria Scoparia Extract …
Matched Description: … Stypocaulon scoparium is a plant/plant extract used in some OTC (over-the-counter) products. …
Matched Description: … Stypocaulon scoparium is a plant/plant extract used in some OTC (over-the-counter) products. …
SEA-BCMA
Investigational
Matched Synonyms: … Anti-bcma antibody sea-bcma ... Nonfucosylated humanized immunoglobulin G1 (IgG1) monoclonal antibody targeting B-cell maturation antigen …
Iva annua pollen
Iva annua pollen is the pollen of the Iva annua plant. Iva annua pollen is mainly used in allergenic testing.
Approved
Matched Synonyms: … rough marshelder pollen extract …
Matched Categories: … Non-Standardized Pollen Allergenic Extract …
Matched Categories: … Non-Standardized Pollen Allergenic Extract …
Dolichovespula arenaria venom protein
Dolichovespula arenaria venom protein is an extract of Dolichovespula arenaria venom. Dolichovespula arenaria venom protein is used in allergenic testing.
Approved
Matched Synonyms: … Dolichovespula arenaria venom protein extract …
Matched Description: … Dolichovespula arenaria venom protein is an extract of Dolichovespula arenaria venom. …
Matched Categories: … Bee and Wasp Venom ... Allergenic Extracts ... Standardized Insect Venom Allergenic Extract …
Matched Description: … Dolichovespula arenaria venom protein is an extract of Dolichovespula arenaria venom. …
Matched Categories: … Bee and Wasp Venom ... Allergenic Extracts ... Standardized Insect Venom Allergenic Extract …
Citicoline
Citicoline is a donor of choline in biosynthesis of choline-containing phosphoglycerides. It has been investigated for the treatment, supportive care, and diagnosis of Mania, Stroke, Hypomania, Cocaine Abuse, and Bipolar Disorder, among others.
Approved
Experimental
Matched Description: … , Cocaine Abuse, and Bipolar Disorder, among others. ... It has been investigated for the treatment, supportive care, and diagnosis of Mania, Stroke, Hypomania …
Matched Salts name: … Citicoline sodium …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides ... Psychostimulants, Agents Used for ADHD and Nootropics …
Matched Products: … CITICOLINE SODIUM …
Matched Salts name: … Citicoline sodium …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides ... Psychostimulants, Agents Used for ADHD and Nootropics …
Matched Products: … CITICOLINE SODIUM …
STX-100
STX-100 is under investigation in clinical trial NCT01371305 (STX-100 in Patients With Idiopathic Pulmonary Fibrosis (IPF)).
Investigational
Matched Synonyms: … Humanized monoclonal antibody against human integrin alphaVbeta6 …
XMMME-001-RTA
Investigational
Matched Synonyms: … Antimelanoma antibody XMMME-001-RTA …
Matched Categories: … Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins …
Matched Categories: … Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins …
TCN-202
Investigational
Matched Synonyms: … TCN-202 (human anti-cytomegalovirus monoclonal antibody) …
CN-201
CN-201 is a humanized anti-CD3/CD19 bispecific antibody.
Investigational
Matched Synonyms: … recombinant humanized anti-CD3/CD19 bispecific antibody …
Matched Description: … CN-201 is a humanized anti-CD3/CD19 bispecific antibody. …
Matched Description: … CN-201 is a humanized anti-CD3/CD19 bispecific antibody. …
HH-009
HH-009 is a recombinant human IgG4 monoclonal antibody against FGF19 being studied for the treatment of hepatocellular carcinoma.
Investigational
Matched Synonyms: … recombinant human IgG4 monoclonal antibody against FGF19 …
Matched Description: … HH-009 is a recombinant human IgG4 monoclonal antibody against FGF19 being studied for the treatment …
Matched Description: … HH-009 is a recombinant human IgG4 monoclonal antibody against FGF19 being studied for the treatment …
American hazelnut
American hazelnut allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … Hazel seed extract ... Corylus americana nut extract ... Corylus americana (hazelnut) seed extract …
Matched Description: … American hazelnut allergenic extract is used in allergenic testing. …
Matched Categories: … Non-Standardized Food Allergenic Extract ... Non-Standardized Plant Allergenic Extract …
Matched Description: … American hazelnut allergenic extract is used in allergenic testing. …
Matched Categories: … Non-Standardized Food Allergenic Extract ... Non-Standardized Plant Allergenic Extract …
Girentuximab
Girentuximab is a monoclonal chimeric (mouse/human) antibody directed against carbonic anhydrase IX, an antigen expressed in 95% of clear cell renal cell carcinomas (RCC).
Investigational
Matched Synonyms: … Chimeric (human-murine) G250 IgG monoclonal antibody …
Matched Description: … Girentuximab is a monoclonal chimeric (mouse/human) antibody directed against carbonic anhydrase IX, …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … Girentuximab is a monoclonal chimeric (mouse/human) antibody directed against carbonic anhydrase IX, …
Matched Categories: … Amino Acids, Peptides, and Proteins …
LJP-538
Investigational
Matched Synonyms: … Human IgG1 anti-human cytomegalovirus monoclonal antibody LJP538 …
Rocatinlimab
Rocatinlimab is a subcutaneously administered anti-OX40 antibody developed for the treatment of moderate-to-severe atopic dermatitis. In clinical trials, it has shown significant efficacy and safety compared to a placebo. The drug works by targeting the OX40 receptor, which plays a role in the immune response associated with atopic dermatitis. Despite...
Investigational
Matched Synonyms: … Anti-CD134 human monoclonal antibody (IgG1, KHK4083 dimer) …
Matched Description: … injection reactions such as fever and chills have been reported. ... In clinical trials, it has shown significant efficacy and safety compared to a placebo. ... Additionally, the diverse genetic backgrounds of patients may influence the drug’s effectiveness and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … injection reactions such as fever and chills have been reported. ... In clinical trials, it has shown significant efficacy and safety compared to a placebo. ... Additionally, the diverse genetic backgrounds of patients may influence the drug’s effectiveness and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Vibecotamab
Vibecotamab is under investigation in clinical trial NCT05285813 (A Phase II Study of Vibecotamab (Xmab14045) for MRD- Positive AML and MDS After Hypomethylating Agent Failure).
Investigational
Matched Synonyms: … Anti-cd123 x anti-cd3 bispecific antibody xmab14045 …
Matched Description: … investigation in clinical trial NCT05285813 (A Phase II Study of Vibecotamab (Xmab14045) for MRD- Positive AML and …
Matched Description: … investigation in clinical trial NCT05285813 (A Phase II Study of Vibecotamab (Xmab14045) for MRD- Positive AML and …
Epoprostenol
A prostaglandin that is a powerful vasodilator and inhibits platelet aggregation. It is biosynthesized enzymatically from prostaglandin endoperoxides in human vascular tissue. The sodium salt has been also used to treat primary pulmonary hypertension.
Approved
Matched Description: … A prostaglandin that is a powerful vasodilator and inhibits platelet aggregation. ... The sodium salt has been also used to treat primary pulmonary hypertension. …
Matched Salts name: … Epoprostenol sodium …
Matched Categories: … Blood and Blood Forming Organs …
Matched Products: … Epoprostenol Sodium …
Matched Salts name: … Epoprostenol sodium …
Matched Categories: … Blood and Blood Forming Organs …
Matched Products: … Epoprostenol Sodium …
Glofitamab
Glofitamab is a full-length bispecific monoclonal antibody with affinity for both CD20 and CD3 surface antigens found on B- and T-cells, respectively. It has a 2:1 configuration, with bivalency towards CD20 and monovalency towards CD3, and works by recruiting T-cells directly to the surface of cancerous B-cells.[L45698,A258488]
Glofitamab was approved...
Approved
Investigational
Matched Synonyms: … Anti-CD20/CD3 bispecific monoclonal antibody RO7082859 …
Matched Description: … Glofitamab is a full-length bispecific monoclonal antibody with affinity for both CD20 and CD3 surface ... It has a 2:1 configuration, with bivalency towards CD20 and monovalency towards CD3, and works by recruiting ... antigens found on B- and T-cells, respectively. …
Matched Categories: … MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Description: … Glofitamab is a full-length bispecific monoclonal antibody with affinity for both CD20 and CD3 surface ... It has a 2:1 configuration, with bivalency towards CD20 and monovalency towards CD3, and works by recruiting ... antigens found on B- and T-cells, respectively. …
Matched Categories: … MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Simethicone
Simethicone is a silicon based surfactant that decreases the surface tension of gastrointestinal gas bubbles to facilitate their elimination. It has a favourable safety profile as it is not systemically absorbed. Simethicone has been in use since the 1940s but was granted FDA approval in 1952.
Approved
Matched Description: … Simethicone is a silicon based surfactant that decreases the surface tension of gastrointestinal gas …
Matched Mixtures name: … Gelusil Antacid and Anti-gas ... Antacid Plus Extra Strength ... Maalox Plus Extra Strength Tablets …
Matched Categories: … Silicones ... Silicon Compounds …
Matched Products: … LEFAX EXTRA ... Gas-X Extra Strength ... Vivascon Extra Strength …
Matched Mixtures name: … Gelusil Antacid and Anti-gas ... Antacid Plus Extra Strength ... Maalox Plus Extra Strength Tablets …
Matched Categories: … Silicones ... Silicon Compounds …
Matched Products: … LEFAX EXTRA ... Gas-X Extra Strength ... Vivascon Extra Strength …
Displaying drugs 976 - 1000 of 1311 in total