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Displaying drugs 10101 - 10125 of 10540 in total

Ceralasertib

Ceralasertib is under investigation in clinical trial NCT03682289 (Phase II Trial of AZD6738 Alone and in Combination With Olaparib).
Investigational
Matched Iupac: … (R)-imino(methyl)(1-{6-[(3R)-3-methylmorpholin-4-yl]-2-{1H-pyrrolo[2,3-c]pyridin-4-yl}pyrimidin-4-yl} …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Coltuximab ravtansine

Coltuximab ravtansine (SAR3419) targets CD19 and is being investigated for the treatment of acute lymphoblastic leukemia (ALL).
Investigational

Pegilodecakin

Pegilodecakin is under investigation in clinical trial NCT03382912 (Study of Pegilodecakin (LY3500518) With Nivolumab Compared to Nivolumab Alone Second-line Tx in Participants With Metastatic Non-Small Cell Lung Cancer).
Investigational

Mubodina

Mubodina is an investigational drug developed by Adienne Pharma & Biotech. It is a recombinant human minibody directed against complement component C5. It was investigated in various conditions including primary membranoproliferative glomerulonephritis and typical hemolytic uremic syndrome.
Investigational

Col-Treg

Col-Treg is an autologous T-cell therapy comprising type I regulatory T-cells specific for human type II collagen.
Investigational
Matched Synonyms: … Purified autologous type 1 regulatory T lymphocytes specific for human type II collagen …

Seletracetam

Seletracetam is a pyrrolidone derivative and with a structural similarity to newer generation antiepileptic drug levetiracetam. It binds to the same target as levetiracetam but with higher affinity and has shown potent seizure suppression in models of acquired and genetic epilepsy with high CNS tolerability. It is predicted to have...
Investigational
Matched Synonyms: … (2S)-2-((4S)-4-(2,2-Difluoroethenyl)-2-oxopyrrolidin-1-yl)butanamide …
Matched Iupac: … (2S)-2-[(4S)-4-(2,2-difluoroethenyl)-2-oxopyrrolidin-1-yl]butanamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Volociximab

Investigational

Octyldodecanol

Experimental
Matched Synonyms: … 2-Octyl-1-dodecanol …
Matched Iupac: … 2-octyldodecan-1-ol …

D-Levofloxacin

A synthetic fluoroquinolone (FLUOROQUINOLONES) antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
Experimental
Matched Iupac: … (2R)-7-fluoro-2-methyl-6-(4-methylpiperazin-1-yl)-10-oxo-4-oxa-1-azatricyclo[7.3.1.0^{5,13}]trideca-5,7,9 …

Lometrexol

Lometrexol has been used in trials studying the treatment of Lung Cancer, Drug/Agent Toxicity by Tissue/Organ, and Unspecified Adult Solid Tumor, Protocol Specific.
Investigational
Matched Iupac: … (2S)-2-[(4-{2-[(6R)-2-amino-4-oxo-1H,4H,5H,6H,7H,8H-pyrido[2,3-d]pyrimidin-6-yl]ethyl}phenyl)formamido …
Matched Salts cas: … 120408-07-3 …

Parsaclisib

Parsaclisib is under investigation in clinical trial NCT03126019 (An Open-Label Study of Parsaclisib in Relapsed or Refractory Follicular Lymphoma (CITADEL-203)).
Investigational
Matched Iupac: … (4R)-4-{3-[(1S)-1-{4-amino-3-methyl-1H-pyrazolo[3,4-d]pyrimidin-1-yl}ethyl]-5-chloro-2-ethoxy-6-fluorophenyl …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Phosphatidylinositol-3-kinase (Pi3K) inhibitors …

Janagliflozin

Janagliflozin is under investigation in clinical trial NCT03851432 (Janagliflozin Treat Type 2 Diabetes Mellitus (T2DM) Inadequately Controlled With Metformin).
Investigational
Matched Iupac: … (2S,3R,4R,5S,6R)-2-[4-chloro-3-({4-[(1R,3s,5S)-bicyclo[3.1.0]hexan-3-yloxy]phenyl}methyl)phenyl]-6-(hydroxymethyl …

Sibofimloc

Sibofimloc is under investigation in clinical trial NCT03943446 (TAK-018 for Prevention of the Recurrence of Postoperative Crohn's Disease (CD)).
Investigational
Matched Iupac: … 1-[2,7-bis({2-[(2R,3S,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]ethynyl})spiro[fluorene-9,4 ... '-piperidin]-1'-yl]ethan-1-one …

Adegramotide

Investigational

Temelimab

Temelimab is under investigation in clinical trial NCT02782858 (Clinical Trial Assessing the HERV-W Env Antagonist Gnbac1 for Efficacy in MS).
Investigational

Yersinia pestis 195/p antigen (formaldehyde inactivated)

Yersinia pestis 195/p antigen (formaldehyde inactivated) is under investigation in clinical trial NCT02596308 (Immunogenicity and Safety of Subunit Plague Vaccine).
Investigational

COVID19 s-vax loaded autologous dendritic cell vaccine

Dendritic cells (DCs) can be derived and differentiated from peripheral blood mononuclear cells in the presence of specific cytokines and growth factors. These cells are then loaded with antigens produced by a virus or tumor cell and administered as a vaccine. Dendritic Cells (DCs) are showing potential as natural adjuvants...
Investigational

Acetophenone

Experimental
Matched Synonyms: … 1-phenylethanone …
Matched Iupac: … 1-phenylethan-1-one …

Leuvectin

Leuvectin (formerly known as VCL-1102) is a component of gene therapy along with cationic lipid 1,2-dimyristyloxypropyl-3-dimethyl-hydroxyethyl ammonium bromide/dioleyl-phosphatidyl-ethanolamine (DMRIE/DOPE).
Investigational
Matched Description: … known as VCL-1102) is a component of gene therapy along with cationic lipid 1,2-dimyristyloxypropyl-3- …

Cibacron Blue

Experimental
Matched Iupac: … 1-amino-4-{[4-({4-chloro-6-[(2-sulfophenyl)amino]-1,3,5-triazin-2-yl}amino)-3-sulfophenyl]amino}-9,10 …

Prostaglandin G2

A cyclic endoperoxide intermediate produced by the action of CYCLOOXYGENASE on ARACHIDONIC ACID. It is further converted by a series of specific enzymes to the series 2 prostaglandins. [PubChem]
Experimental
Matched Iupac: … (5Z)-7-[(1R,4S,5R,6R)-6-[(1E,3S)-3-hydroperoxyoct-1-en-1-yl]-2,3-dioxabicyclo[2.2.1]heptan-5-yl]hept- …

Alvelestat

Alvelestat has been investigated for the basic science of Chronic Obstructive Pulmonary Disease.
Investigational
Matched Iupac: … N-[(5-methanesulfonylpyridin-2-yl)methyl]-6-methyl-5-(1-methyl-1H-pyrazol-5-yl)-2-oxo-1-[3-(trifluoromethyl ... )phenyl]-1,2-dihydropyridine-3-carboxamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

MK-0812

MK0812 has been used in trials studying the treatment of Relapsing-Remitting Multiple Sclerosis.
Investigational
Matched Iupac: … -6-yl]methyl}cyclopentyl]oxan-4-amine ... (3S,4S)-3-methoxy-N-[(1R,3S)-3-(propan-2-yl)-3-{[3-(trifluoromethyl)-5,6,7,8-tetrahydro-1,6-naphthyridin …

Onatasertib

Onatasertib (CC-223) has been used in trials studying the treatment and basic science of Multiple Myeloma, Glioblastoma Multiforme, HepatoCellular Carcinoma, Non-small Cell Lung Cancer, and Diffuse Large B-Cell Lymphoma, among others.
Investigational
Matched Iupac: … 7-[6-(2-hydroxypropan-2-yl)pyridin-3-yl]-1-[(1r,4r)-4-methoxycyclohexyl]-1H,2H,3H,4H-pyrazino[2,3-b][ …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Laniquidar

Laniquidar has been used in trials studying the treatment of Breast Cancer.
Investigational
Matched Iupac: … ^{3,7}]tetradeca-1(14),3,5,10,12-pentaene-6-carboxylate ... methyl 2-[1-(2-{4-[(quinolin-2-yl)methoxy]phenyl}ethyl)piperidin-4-ylidene]-4,7-diazatricyclo[8.4.0.0 …
Displaying drugs 10101 - 10125 of 10540 in total