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Displaying drugs 10126 - 10150 of 12396 in total
Peldesine is a potent inhibitor of human CCRF-CEM T-cell proliferation. It has undergone phase I trials for the treatment of Human Immunodeficiency Virus (HIV) infections.
Investigational
Matched Synonyms: … 2-Amino-3,5-dihydro-7-(3-pyridylmethyl)-4H-pyrrolo(3,2-d)pyrimidin-4-one …
Matched Iupac: … 2-amino-7-[(pyridin-3-yl)methyl]-1H,4H,5H-pyrrolo[3,2-d]pyrimidin-4-one …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Pipequaline is an anticonflict & anticonvulsant quinoline derivative. It is an anxiolytic drug that was never marketed. It presents a unique chemical structure that does not follow the structural properties of other drugs of its class. Pipequaline has a similar pharmacological profile to the reported for the benzodiazepines. However, it...
Experimental
Matched Synonyms: … 2-Phenyl-4-(2-(4-piperidyl)ethyl)quinoline …
Matched Iupac: … 2-phenyl-4-[2-(piperidin-4-yl)ethyl]quinoline …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Experimental
Matched Synonyms: … 2-(4-morpholinyl)ethanesulfonic acid ... 2-morpholinoethanesulphonic acid ... 2-(N-morpholino)ethanesulfonic acid …
Matched Name: … 2-(N-morpholino)ethanesulfonic acid …
Matched Iupac: … 4-(2-sulfonatoethyl)morpholin-4-ium …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Experimental
Matched Categories: … Heterocyclic Compounds, 1-Ring …
ASP4058 has been used in trials studying Food Effect of ASP4058 and Pharmacokinetics of ASP4058.
Investigational
Matched Iupac: … 5-{5-[3-(trifluoromethyl)-4-{[(2S)-1,1,1-trifluoropropan-2-yl]oxy}phenyl]-1,2,4-oxadiazol-3-yl}-1H-1,3 …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …
Efatutazone has been used in trials studying the treatment of Lymphoma, Liposarcoma, Solid Tumors, Multiple Myeloma, and Recurrent Thyroid Cancer, among others.
Investigational
Matched Iupac: … 5-[(4-{[6-(4-amino-3,5-dimethylphenoxy)-1-methyl-1H-1,3-benzodiazol-2-yl]methoxy}phenyl)methyl]-1,3-thiazolidine …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Golvatinib has been investigated for the treatment of Platinum-Resistant Squamous Cell Carcinoma of the Head and Neck.
Investigational
Matched Iupac: … N'1-{2-fluoro-4-[(2-{[4-(4-methylpiperazin-1-yl)piperidine-1-carbonyl]amino}pyridin-4-yl)oxy]phenyl}- …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Vascular Endothelial Growth Factor Receptor-2, antagonists & inhibitors …
JNJ-37822681 has been used in trials studying the treatment of Schizophrenia.
Investigational
Matched Iupac: … N-{1-[(3,4-difluorophenyl)methyl]piperidin-4-yl}-6-(trifluoromethyl)pyridazin-3-amine …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
CE-326,597 has been used in trials studying the treatment of Obesity.
Investigational
Matched Iupac: … -1(14),3,5,10,12-pentaen-9-yl]-N-(propan-2-yl)acetamide ... N-benzyl-2-[(7S)-7-[(1H-indol-3-yl)methyl]-8-oxo-3-phenyl-2,4,5,9-tetraazatricyclo[8.4.0.0^{2,6}]tetradeca …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …
Emicerfont has been used in trials studying the diagnostic and treatment of Social Anxiety Disorder and Irritable Bowel Syndrome (IBS).
Investigational
Matched Iupac: … 1-{1-[1-(4-methoxy-2-methylphenyl)-6-methyl-1H,2H,3H-pyrrolo[2,3-b]pyridin-4-yl]-1H-pyrazol-3-yl}imidazolidin ... -2-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Etamicastat is under investigation in clinical trial NCT02840565 (Tolerability, Pharmacokinetics and Pharmacodynamics of Six Multiple Rising Dose Regimens of BIA 5-453).
Investigational
Matched Iupac: … 5-(2-aminoethyl)-1-[(3R)-6,8-difluoro-3,4-dihydro-2H-1-benzopyran-3-yl]-2,3-dihydro-1H-imidazole-2-thione …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …
Nacubactam is under investigation in clinical trial NCT03174795 (A Study to Investigate the Pharmacokinetics of RO7079901 and Meropenem in Participants With a Complicated Urinary Tract Infection).
Investigational
Matched Iupac: … [(1R,2S,5R)-2-[(2-aminoethoxy)carbamoyl]-7-oxo-1,6-diazabicyclo[3.2.1]octan-6-yl]oxidanesulfonic acid …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Rilematovir is under investigation in clinical trial NCT04056611 (Effects of JNJ-53718678 in Adult and Adolescent Participants Who Had a Hematopoietic Stem Cell Transplantation and Who Are Infected With Respiratory Syncytial Virus (RSV)).
Investigational
Matched Iupac: … 3-{[5-chloro-1-(3-methanesulfonylpropyl)-1H-indol-2-yl]methyl}-1-(2,2,2-trifluoroethyl)-1H,2H,3H-imidazo ... [4,5-c]pyridin-2-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …
BTRX-335140 is under investigation in clinical trial NCT04221230 (Study in Major Depressive Disorder With BTRX-335140 vs Placebo).
Investigational
Matched Iupac: … 1-[6-ethyl-8-fluoro-4-methyl-3-(3-methyl-1,2,4-oxadiazol-5-yl)quinolin-2-yl]-N-(oxan-4-yl)piperidin-4 …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …
AZD8529 is under investigation in clinical trial NCT00921804 (Study to Assess the Efficacy, Safety, and Tolerability of AZD8529 in Adult Schizophrenia Patients).
Investigational
Matched Iupac: … 7-methyl-5-{3-[(piperazin-1-yl)methyl]-1,2,4-oxadiazol-5-yl}-2-{[4-(trifluoromethoxy)phenyl]methyl}-2,3 ... -dihydro-1H-isoindol-1-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …
Fisogatinib is under investigation in clinical trial NCT04194801 (A Phase Ib/ii Study of Fisogatinib(blu-554) in Subjects With Hepatocellular Carcinoma).
Investigational
Matched Iupac: … N-[(3S,4S)-3-{[6-(2,6-dichloro-3,5-dimethoxyphenyl)quinazolin-2-yl]amino}oxan-4-yl]prop-2-enamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …
Experimental
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Neurokinin-1 Receptor Antagonists …
Investigational
Matched Iupac: … (3R,4R)-4-[(3,4-dimethoxyphenyl)methyl]-3-[(4-hydroxy-3-methoxyphenyl)methyl]oxolan-2-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Experimental
Matched Iupac: … (3S)-3-amino-4-[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy) …
Experimental
Matched Iupac: … 3-amino-N-[(1S)-1-{[(1S)-1-{[(2S,3R,4S)-1-cyclohexyl-3,4-dihydroxy-6-methylheptan-2-yl]carbamoyl}-2-( ... 1H-imidazol-5-yl)ethyl]carbamoyl}-2-(4-methoxyphenyl)ethyl]-3-methylbutanamide …
Experimental
Matched Name: … 3-(Benzyloxy)Pyridin-2-Amine …
Matched Iupac: … 3-(benzyloxy)pyridin-2-amine …
Experimental
Matched Name: … 2-(Oxalyl-Amino)-Benzoic Acid …
Matched Iupac: … 2-(carboxyformamido)benzoic acid …
Experimental
Matched Name: … S-9-(2-hydroxypropyl)adenine …
Matched Iupac: … (2S)-1-(6-amino-9H-purin-9-yl)propan-2-ol …
Experimental
Matched Name: … 2-carboxypropyl-coenzyme A …
Matched Iupac: … -2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)methyl]-2-hydroxy-3-methylbutanamido]propanamido ... }ethyl)sulfanyl]-2-methylpropanoic acid ... (2R)-3-[(2-{3-[(2R)-3-[({[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)oxolan …
Isoamyl 2 Cyanoacrylate is under investigation in clinical trial NCT02698644 (Hysteroscopic Tubal Occlusion With the Use of Iso Amyl-2-cyanoacrylate).
Investigational
Matched Name: … Isopentyl 2-cyanoacrylate …
Matched Iupac: … 3-methylbutyl 2-cyanoprop-2-enoate …
Matched Description: … With the Use of Iso Amyl-2-cyanoacrylate). ... Isoamyl 2 Cyanoacrylate is under investigation in clinical trial NCT02698644 (Hysteroscopic Tubal Occlusion …
Displaying drugs 10126 - 10150 of 12396 in total