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Displaying drugs 10226 - 10250 of 12317 in total
Experimental
Matched Categories: … Neurokinin-1 Receptor Antagonists …
Investigational
Dexamethasone isonicotinate is an anti-inflammatory, anti-allergic glucocorticoid that can be administered orally, by inhalation, topically, and parenterally. Its unintended mineralocorticoid action may cause salt and water retention.
Vet approved
Matched Synonyms: … Dexamethasone 21-(4-Pyridinecarboxylate) …
Matched Iupac: … ]heptadeca-3,6-dien-14-yl]-2-oxoethyl pyridine-4-carboxylate ... 2-[(1R,2S,10S,11S,13R,14R,15S,17S)-1-fluoro-14,17-dihydroxy-2,13,15-trimethyl-5-oxotetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵ …
Volrubigene ralaparvovec is under investigation in clinical trial NCT03223194 (Gene Transfer Clinical Study in Crigler-najjar Syndrome).
Investigational
A glucocorticoid with the general properties of corticosteroids. It has been used by mouth in the treatment of all conditions in which corticosteroid therapy is indicated except adrenal-deficiency states for which its lack of sodium-retaining properties makes it less suitable than hydrocortisone with supplementary fludrocortisone. (From Martindale, The Extra Pharmacopoeia,...
Experimental
Matched Iupac: … (1R,2R,3aS,3bS,5S,9aR,9bS,10S,11aS)-5-fluoro-1,10-dihydroxy-1-(2-hydroxyacetyl)-2,9a,11a-trimethyl-1H …
Tanaproget (NSP-989) is an investigational non-steroidal progestin. It is a high affinity, high efficacy agonist of the progesterone receptor (PR) with a much more selective binding profile relative to most conventional progestins. Because of this tanaproget may prove to produce fewer side effects in comparison. It is currently in the...
Investigational
Matched Iupac: … 5-(4,4-dimethyl-2-sulfanylidene-2,4-dihydro-1H-3,1-benzoxazin-6-yl)-1-methyl-1H-pyrrole-2-carbonitrile …
Matched Description: … An analog of tanaproget, 4-fluoropropyltanaproget (18F), has been developed as a radiotracer for imaging …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Mirodenafil has been used in trials studying the treatment and supportive care of Kidney Diseases, Urologic Diseases, Renal Insufficiency, Erectile Dysfunction, and Male Erectile Dysfunction.
Investigational
Matched Iupac: … 5-ethyl-2-(5-{[4-(2-hydroxyethyl)piperazin-1-yl]sulfonyl}-2-propoxyphenyl)-7-propyl-3H,4H,5H-pyrrolo[ ... 3,2-d]pyrimidin-4-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Anagliptin is under investigation for the treatment of LDL Cholesterol, Coronary Disease, Diabetes Mellitus, Glycosylated Hemoglobin, and Dipeptidyl-Peptidase 4 Inhibitors.
Investigational
Matched Iupac: … N-[2-({2-[(2S)-2-cyanopyrrolidin-1-yl]-2-oxoethyl}amino)-2-methylpropyl]-2-methylpyrazolo[1,5-a]pyrimidine …
Matched Description: … Cholesterol, Coronary Disease, Diabetes Mellitus, Glycosylated Hemoglobin, and Dipeptidyl-Peptidase 4
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Henatinib has been used in trials studying the treatment of Advanced Solid Cancer.
Investigational
Matched Iupac: … (3Z)-5-fluoro-3-({5-[(2R)-2-hydroxy-3-(morpholin-4-yl)propyl]-3-methyl-4-oxo-1H,4H,5H,6H,7H,8H-pyrrolo …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Experimental
Matched Iupac: … 5-(heptan-3-yl)-3-[(trichloromethyl)sulfanyl]imidazolidine-2,4-dione …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Lanifibranor is under investigation in clinical trial NCT03008070 (Phase 2b Study in NASH to Assess IVA337).
Investigational
Matched Iupac: … 4-[1-(1,3-benzothiazole-6-sulfonyl)-5-chloro-1H-indol-2-yl]butanoic acid …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Padsevonil is under investigation in clinical trial NCT03695094 (A Study in Participants With Epilepsy, to Evaluate the Pharmacokinetics, Safety and Tolerability of Oxcarbazepine on Padsevonil).
Investigational
Matched Iupac: … (4R)-4-(2-chloro-2,2-difluoroethyl)-1-{[2-(methoxymethyl)-6-(trifluoromethyl)imidazo[2,1-b][1,3,4]thiadiazol …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Centhaquine is under investigation in clinical trial NCT04045327 (Efficacy of PMZ-2010 (Centhaquine) a Resuscitative Agent for Hypovolemic Shock).
Investigational
Matched Iupac: … 2-{2-[4-(3-methylphenyl)piperazin-1-yl]ethyl}quinoline …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Investigational
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Experimental
Matched Name: … (5-(PYRIDIN-3-YL)FURAN-2-YL)METHANAMINE …
Matched Iupac: … 1-[5-(pyridin-3-yl)furan-2-yl]methanamine …
Experimental
Matched Iupac: … (2R,3S,4R,5R,6R)-5-amino-2-(aminomethyl)-6-{[(1R,2S,3S,4R,6S)-4,6-diamino-3-{[(2S,3R,4S,5S,6R)-4-amino ... -3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-2-hydroxycyclohexyl]oxy}oxane-3,4-diol …
Investigational
Experimental
Matched Name: … N-[3-(aminomethyl)benzyl]acetamidine …
Matched Iupac: … N-{[3-(aminomethyl)phenyl]methyl}ethanimidamide …
Experimental
Matched Name: … (2S)-2-Methyl-3-phenylpropanoic acid …
Matched Iupac: … (2S)-2-methyl-3-phenylpropanoic acid …
Experimental
Matched Name: … N-(3-AMINOPROPYL)-2-NITROBENZENAMINE …
Experimental
Matched Iupac: … 5-amino-N-(2,6-difluorophenyl)-3-[(4-sulfamoylphenyl)amino]-1H-1,2,4-triazole-1-carbothioamide …
Rilapladib is the third genomics-derived small molecule drug arising from the Human Genome Sciences-GlaxoSmithKline collaboration to enter clinical development. It is a lipoprotein-associated phospholipase A2 (Lp-PLA2) inhibitor. Lp-PLA2 is an enzyme associated with the formation of atherosclerotic plaques.
Investigational
Matched Iupac: … 2-(2-{[(2,3-difluorophenyl)methyl]sulfanyl}-4-oxo-1,4-dihydroquinolin-1-yl)-N-[1-(2-methoxyethyl)piperidin ... -4-yl]-N-{[4'-(trifluoromethyl)-[1,1'-biphenyl]-4-yl]methyl}acetamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Displaying drugs 10226 - 10250 of 12317 in total