Displaying drugs 1026 - 1050 of 1129 in total
Allogenic Donor CD362-enriched Human Umbilical Cord-derived Mesenchymal Stem Cells
ORBCEL-C™ is the trade name of a product composed of highly purified stromal cells derived from the human umbilical cord. The isolated cells are expanded in culture and are able to be used allogenically -- meaning that one donor’s cells can be given to other unrelated patients. These cells are...
Investigational
Matched Synonyms: … Allogeneic donor CD362 enriched human umbilical cord-derived mesenchymal stromal cells …
Matched Name: … Allogenic Donor CD362-enriched Human Umbilical Cord-derived Mesenchymal Stem Cells …
Matched Description: … The isolated cells are expanded in culture and are able to be used allogenically -- meaning that one ... mesenchymal stem cells (UC-MSCs); UC-MSCs share stemness markers with both embryonic stem cells (ESCs) and ... adult mesenchymal stem cells (MSCs); this feature allows them to be hypoimmunogenic and non-inducible …
Matched Name: … Allogenic Donor CD362-enriched Human Umbilical Cord-derived Mesenchymal Stem Cells …
Matched Description: … The isolated cells are expanded in culture and are able to be used allogenically -- meaning that one ... mesenchymal stem cells (UC-MSCs); UC-MSCs share stemness markers with both embryonic stem cells (ESCs) and ... adult mesenchymal stem cells (MSCs); this feature allows them to be hypoimmunogenic and non-inducible …
RR001
RR001 is an investigational gene therapy consisting of autologous human adipose perivascular stromal cells genetically modified to secrete soluble tumour necrosis factor-related apoptosis-inducing ligand (AD-PC sTRAIL).
Investigational
Matched Synonyms: … autologous human adipose perivascular stromal cells genetically modified to secrete soluble tumour necrosis …
Matched Description: … RR001 is an investigational gene therapy consisting of autologous human adipose perivascular stromal …
Matched Description: … RR001 is an investigational gene therapy consisting of autologous human adipose perivascular stromal …
Mubodina
Mubodina is an investigational drug developed by Adienne Pharma & Biotech. It is a recombinant human minibody directed against complement component C5. It was investigated in various conditions including primary membranoproliferative glomerulonephritis and typical hemolytic uremic syndrome.
Investigational
Matched Synonyms: … Neutralizing scFv dimer to C5 fused at the C terminal end to the Fc domains of human IgG1 …
Matched Description: … It was investigated in various conditions including primary membranoproliferative glomerulonephritis and ... It is a recombinant human minibody directed against complement component C5. …
Matched Description: … It was investigated in various conditions including primary membranoproliferative glomerulonephritis and ... It is a recombinant human minibody directed against complement component C5. …
STM-217
Investigational
Matched Synonyms: … Soluble receptor fused to part of an antibody that is designed to block the growth factor activin a …
Interferon alfa-2a
Interferon a (human leukocyte protein moiety reduced). A type I interferon consisting of 165 amino acid residues with lysine in position 23. This protein is produced by recombinant DNA technology and resembles interferon secreted by leukocytes. It is used extensively as an antiviral or antineoplastic agent. An oral form is...
Approved
Investigational
Matched Synonyms: … Recombinant human interferon alfa-2a ... Recombinant human interferon-alfa-2a …
Matched Description: … This protein is produced by recombinant DNA technology and resembles interferon secreted by leukocytes ... Interferon a (human leukocyte protein moiety reduced). …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Intercellular Signaling Peptides and Proteins …
Matched Description: … This protein is produced by recombinant DNA technology and resembles interferon secreted by leukocytes ... Interferon a (human leukocyte protein moiety reduced). …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Intercellular Signaling Peptides and Proteins …
Anvatabart opadotin
Investigational
Matched Synonyms: … tyrosine-protein kinase erbB-2, EGFR2, HER2, HER-2, p185c-erbB2, NEU, CD340)], humanized monoclonal antibody ... HER2) (human-Mus musculus monoclonal Amab788 γ1-chain), disulfide with human-Mus musculus monoclonal ... Immunoglobulin G1 [121-(4-acetylphenylalanine),de-450-lysine], anti-(human epidermal growth factor receptor …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Eftrenonacog alfa
Eftrenonacog alfa is a long-acting recombinant fusion protein used in the treatment of hemophilia B. It is comprised of a single molecule of human factor IX (FIX) covalently linked to the constant region (Fc) domain of human IgG1 via recombinant DNA technology in a human embryonic kidney cell line (HEK293H)...
Approved
Investigational
Matched Synonyms: … Recombinant human coagulation factor IX, FC Fusion protein …
Matched Description: … benefits of prolonged therapeutic efficacy, less frequent intravenous injections for patient convenience and ... It was first approved by the FDA in March 2014 and later approved by the EMA in May 2016. ... blood disorder with an incidence of approximately once every 30,000 male births in all populations and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes …
Matched Description: … benefits of prolonged therapeutic efficacy, less frequent intravenous injections for patient convenience and ... It was first approved by the FDA in March 2014 and later approved by the EMA in May 2016. ... blood disorder with an incidence of approximately once every 30,000 male births in all populations and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes …
CRS-207
Investigational
Matched Synonyms: … Live-attenuated Listeria monocytogenes actA/inlB/human mesothelin (hMeso) Strain hMeso38 …
Roledumab
Roledumab is under investigation in clinical trial NCT02287896 (Pharmacokinetics and Safety of Roledumab in Rhd-negative Pregnant Women Carrying an Rhd-positive Foetus).
Investigational
Matched Synonyms: … -kappa, anti-(homo sapiens rhd(rhesus blood group d antigen, rhd, cd240d)), homo sapiens monoclonal antibody …
Matched Description: … Roledumab is under investigation in clinical trial NCT02287896 (Pharmacokinetics and Safety of Roledumab …
Matched Description: … Roledumab is under investigation in clinical trial NCT02287896 (Pharmacokinetics and Safety of Roledumab …
Tegoprubart
Investigational
Matched Synonyms: … Humanized Anti-Cd40Lg Igg1, Kappa Monoclonal Antibody With Heavy Chain C220S/C226S/C229S/P238S Substitutions …
Dornase alfa
Dornase alfa is a biosynthetic form of human deoxyribunuclease I (DNase I) enzyme. It is produced in genetically modified Chinese hamster ovary (CHO) cells using recombinant DNA technology. The 260-amino acid sequence of dornase alfa is identical to the endogenous human enzyme. Dornase alfa cleaves extracellular DNA to 5´-phosphodinucleotide and...
Approved
Matched Synonyms: … Deoxyribonuclease (human clone 18-1 protein moiety) …
Matched Description: … Enzymatic breakdown of this extracellular DNA appears to reduce sputum viscosity and viscoelasticity. ... Dornase alfa cleaves extracellular DNA to 5´-phosphodinucleotide and 5´-phosphooligonucleotide end products ... Dornase alfa is a biosynthetic form of human deoxyribunuclease I (DNase I) enzyme. …
Matched Categories: … Recombinant Human Deoxyribonuclease 1 ... Amino Acids, Peptides, and Proteins ... Cough and Cold Preparations ... Enzymes and Coenzymes …
Matched Description: … Enzymatic breakdown of this extracellular DNA appears to reduce sputum viscosity and viscoelasticity. ... Dornase alfa cleaves extracellular DNA to 5´-phosphodinucleotide and 5´-phosphooligonucleotide end products ... Dornase alfa is a biosynthetic form of human deoxyribunuclease I (DNase I) enzyme. …
Matched Categories: … Recombinant Human Deoxyribonuclease 1 ... Amino Acids, Peptides, and Proteins ... Cough and Cold Preparations ... Enzymes and Coenzymes …
Hemoglobin crosfumaril
Hemoglobin in which the alpha-subunit are cross-linked intramolecularly.
Experimental
Matched Synonyms: … Hemoglobin A0 (human alpha2 beta2 tetrameric subunit), alpha-chain 99,99'-diamide with (E)-2-butenoic …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Blood and Related Products ... Blood Substitutes and Perfusion Solutions ... Blood Substitutes and Plasma Protein Fractions …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Blood and Related Products ... Blood Substitutes and Perfusion Solutions ... Blood Substitutes and Plasma Protein Fractions …
Valoctocogene roxaparvovec
Valoctocogene roxaparvovec is an adeno-associated virus serotype 5 (AAV5) based gene therapy vector that expresses the B-domain deleted SQ form of human coagulation factor VIII (hFVIII-SQ). The expression of hFVIII-SQ is driven by a liver-specific promoter, which enables hepatocytes to produce factor VIII protein and increase the levels of active...
Approved
Investigational
Matched Synonyms: … DNA (synthetic adeno-associated virus 5 vector BMN 270 human blood-coagulation factor VIII SQ variant-specifying …
Matched Description: … hFVIII-SQ is driven by a liver-specific promoter, which enables hepatocytes to produce factor VIII protein and ... [L43282,A252807] Valoctocogene roxaparvovec was approved by EMA in September 2022 and is indicated for ... A252797] As opposed to these therapies, valoctocogene roxaparvovec offers the advantage of continuous and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Cellular and Gene Therapy …
Matched Description: … hFVIII-SQ is driven by a liver-specific promoter, which enables hepatocytes to produce factor VIII protein and ... [L43282,A252807] Valoctocogene roxaparvovec was approved by EMA in September 2022 and is indicated for ... A252797] As opposed to these therapies, valoctocogene roxaparvovec offers the advantage of continuous and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Cellular and Gene Therapy …
Axalimogene filolisbac
Axalimogene filolisbac is under investigation in clinical trial NCT02853604 (Study of ADXS11-001 in Subjects With High Risk Locally Advanced Cervical Cancer).
Investigational
Matched Synonyms: … Live, attenuated listeria monocytogenes bacteria, expressing human papilloma virus type 16-e7 tumor antigen …
Rexlemestrocel-L
Rexlemestrocel-L is an investigational human bone marrow-derived allogeneic mesenchymal precursor cell (MPC) product. It is being investigated in various cardiac conditions, such as chronic heart failure and acute myocardial infarction.
Investigational
Matched Synonyms: … Allogeneic human bone marrow-derived mpc …
Matched Description: … It is being investigated in various cardiac conditions, such as chronic heart failure and acute myocardial ... Rexlemestrocel-L is an investigational human bone marrow-derived allogeneic mesenchymal precursor cell …
Matched Description: … It is being investigated in various cardiac conditions, such as chronic heart failure and acute myocardial ... Rexlemestrocel-L is an investigational human bone marrow-derived allogeneic mesenchymal precursor cell …
Sulfanilamide
Sulfanilamide is a molecule containing the sulfonamide functional group attached to an aniline.
Approved
Matched Synonyms: … Prontosil album …
Matched Categories: … Genito Urinary System and Sex Hormones ... Sulfonamides and trimethoprim ... Gynecological Antiinfectives and Antiseptics …
Matched Categories: … Genito Urinary System and Sex Hormones ... Sulfonamides and trimethoprim ... Gynecological Antiinfectives and Antiseptics …
Imalumab
Imalumab is under investigation in clinical trial NCT02540356 (Phase 1/2a Two-arm Dose-escalation Study of BAX69 in Subjects With Malignant Ascites of Ovarian Cancer).
Investigational
Matched Synonyms: … migration inhibitory factor, glycosylation-inhibiting factor, glif, gif)), homo sapiens monoclonal antibody …
Activated charcoal
Activated charcoal, or activated carbon, is an amorphous form of carbon prepared from incomplete combustion of carbonaceous organic matter. It is activated by an oxidizing gas flow at high temperature passed over its surface to make a fine network of pores, producing a material with large surface area and high...
Approved
Matched Description: … oral ingestion of certain medications or poisons by absorbing most drugs and toxins. ... passed over its surface to make a fine network of pores, producing a material with large surface area and ... It is used as a gastric decontaminant and emergency medication to treat poisonings following excessive …
Matched Categories: … Alimentary Tract and Metabolism ... Antacids and Adsorbents …
Matched Products: … Humco Charcoal Activated …
Matched Categories: … Alimentary Tract and Metabolism ... Antacids and Adsorbents …
Matched Products: … Humco Charcoal Activated …
Luteinizing hormone
Approved
Matched Synonyms: … Luteinising hormone (human) …
Matched Mixtures name: … MENOGON 75 IU Powder and Solvent for solution for Injection …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Mixtures name: … MENOGON 75 IU Powder and Solvent for solution for Injection …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
BS-001
BS-001 is a recombinant oncolytic herpes simplex virus type II (OH2) therapeutic injection (Vero cell) for human use (rHSV2hGM-CSF).
Investigational
Matched Synonyms: … Recombinant Oncolytic Herpes Simplex Virus Type II (OH2) Therapeutic Injection (Vero Cell) for Human …
Matched Description: … is a recombinant oncolytic herpes simplex virus type II (OH2) therapeutic injection (Vero cell) for human …
Matched Description: … is a recombinant oncolytic herpes simplex virus type II (OH2) therapeutic injection (Vero cell) for human …
OTL-103
Investigational
Matched Synonyms: … Autologous CD34+ cells transfected with lentiviral vector containing the human WAS cDNA (Telethon 003 …
Cinrebafusp alfa
Investigational
Matched Synonyms: … LINKER) FUSION PROTEIN WITH LIPOCALIN 2 (HUMAN MU ... (S228>P,F234>A,L235>A) IMMUNOGLOBULIN G4-KAPPA (CHIMERIC HUMAN-MUS MUSCULUS, ANTI-(RECEPTOR TYROSINE-PROTEIN ... IMMUNOGLOBULIN G4 (228-PROLINE, 234-ALANINE, 235-ALANINE), ANTI-(HUMAN TYROSINE KINASE RECEPTOR HER2) …
Prezatide
Prezatide is a tripeptide consisting of glycine, histidine, and lysine which readily forms a complex with copper ions . Prezatide is used in cosmetic products for the skin and hair. It is known to aid wound healing and its potential applications in chronic obstructive pulmonary disease and metastatic colon cancer...
Experimental
Matched Synonyms: … Growth-modulating peptide (human) …
Matched Description: … It is known to aid wound healing and its potential applications in chronic obstructive pulmonary disease ... Prezatide is used in cosmetic products for the skin and hair. ... Prezatide is a tripeptide consisting of glycine, histidine, and lysine which readily forms a complex …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … It is known to aid wound healing and its potential applications in chronic obstructive pulmonary disease ... Prezatide is used in cosmetic products for the skin and hair. ... Prezatide is a tripeptide consisting of glycine, histidine, and lysine which readily forms a complex …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Pelacarsen
Pelacarsen is under investigation in clinical trial NCT03070782 (Phase 2 Study of ISIS 681257 (Akcea-apo(a)-lrx) in Participants With Hyperlipoproteinemia(a) and Cardiovascular Disease).
Investigational
Matched Synonyms: … Isis-681257 (galnac3--conjugated aso targeting human lipoprotein (a)) free acid …
Matched Description: … NCT03070782 (Phase 2 Study of ISIS 681257 (Akcea-apo(a)-lrx) in Participants With Hyperlipoproteinemia(a) and …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Matched Description: … NCT03070782 (Phase 2 Study of ISIS 681257 (Akcea-apo(a)-lrx) in Participants With Hyperlipoproteinemia(a) and …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Beremagene geperpavec
Beremagene geperpavec is a live, replication-defective herpes simplex virus type 1 (HSV-1)-based vector therapy. Developed by Krystal Biotech, it was first approved by the FDA on May 19, 2023, for the treatment of wounds associated with dystrophic epidermolysis bullosa (DEB). DEB is caused by mutations in the COL7A1 gene that...
Approved
Matched Synonyms: … Dna (recombinant herpes simplex virus type 1 strain kos plasmid vector kb103 human collagen col7a1-specifying …
Matched Categories: … Cellular and Gene Therapy ... Preparations for Treatment of Wounds and Ulcers …
Matched Categories: … Cellular and Gene Therapy ... Preparations for Treatment of Wounds and Ulcers …
Displaying drugs 1026 - 1050 of 1129 in total