Displaying drugs 1026 - 1050 of 1654 in total
Ivonescimab
Ivonescimab is under investigation in clinical trial NCT05184712 (Phase 3 Clinical Study of AK112 for NSCLC Patients).
Investigational
Matched Synonyms: … IMMUNOGLOBULIN G1 (240-ALANINE,241-ALANINE), ANTI-(HUMAN VASCULAR ENDOTHELIAL GROWTH FACTOR A) (HUMAN-MUS ... .GAMMA.1-CHAIN) FUSION PROTEIN WITH PEPTIDE LINKER (GGGS)4 FUSION PROTEIN WITH IMMUNOGLOBULIN ANTI-(HUMAN …
Ponsegromab
Ponsegromab is under investigation in clinical trial NCT05492500 (A Study of Ponsegromab in People With Heart Failure).
Investigational
Matched Synonyms: … ) (human-mus musculus monoclonal pf-06946860 .gamma.1-chain), disulfide with human-mus musculus monoclonal ... Immunoglobulin g1 (237-alanine,238-alanine,240-alanine), anti-(human growth differentiation factor 15 …
Lerodalcibep
Lerodalcibep is under investigation in clinical trial NCT05004675 (Trial to Evaluate Efficacy and Safety of LIB003 and Inclisiran in High-risk CVD Patients).
Investigational
Matched Synonyms: … from human tenth fibronectin type iii domain, fused via peptidyl linker (97gsgsgs102) to human serum ... Engineered binding protein (1-96) anti-(human proprotein convertase subtilisin/kexin type 9), derived ... Protein lib003 (recombinant human proprotein convertase subtilisin/kexin type 9 ligand-binding tenth …
Matched Description: … of LIB003 and Inclisiran in High-risk CVD Patients). ... Lerodalcibep is under investigation in clinical trial NCT05004675 (Trial to Evaluate Efficacy and Safety …
Matched Description: … of LIB003 and Inclisiran in High-risk CVD Patients). ... Lerodalcibep is under investigation in clinical trial NCT05004675 (Trial to Evaluate Efficacy and Safety …
Nemvaleukin alfa
Investigational
Matched Synonyms: … -chain (human) ... 2 receptor α-chain (human) ... human interleukin 2 fragment (1-59), variant (Cys125>Ser51), fused via peptidyl linker (60GG61) to human …
DADLE
A delta-selective opioid (ANALGESICS, OPIOID). It can cause transient depression of mean arterial blood pressure and heart rate.
Experimental
Matched Synonyms: … L-Tyrosyl-D-alanylglycyl-L-phenylalanyl-D-leucine ... H-Tyr-D-Ala-Gly-Phe-D-Leu …
Matched Description: … It can cause transient depression of mean arterial blood pressure and heart rate. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … It can cause transient depression of mean arterial blood pressure and heart rate. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Phenylacetylglutamine
Investigational
Matched Synonyms: … Phenylacetyl-l-glutamine ... L-glutamine, n2-(phenylacetyl)- …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
L-N(omega)-nitroarginine-(4R)-amino-L-proline amide
Experimental
Matched Name: … L-N(omega)-nitroarginine-(4R)-amino-L-proline amide …
L-Alfa-Lysophosphatidylcholine, Lauroyl
Experimental
Matched Name: … L-Alfa-Lysophosphatidylcholine, Lauroyl …
L-erythro-7,8-dihydrobiopterin
7,8-Dihydrobiopterin is an inhibitor of the enzyme dihydroneopterin aldolase (DHNA), which catalyzes the conversion of 7,8-Dihydrobiopterin to 6-hydroxymethyl-7,8-dihydropterin and glycolaldehyde.
Experimental
Matched Synonyms: … L-erythro-q-Dihydrobiopterin …
Matched Name: … L-erythro-7,8-dihydrobiopterin …
Matched Description: … (DHNA), which catalyzes the conversion of 7,8-Dihydrobiopterin to 6-hydroxymethyl-7,8-dihydropterin and …
Matched Categories: … Enzymes and Coenzymes …
Matched Name: … L-erythro-7,8-dihydrobiopterin …
Matched Description: … (DHNA), which catalyzes the conversion of 7,8-Dihydrobiopterin to 6-hydroxymethyl-7,8-dihydropterin and …
Matched Categories: … Enzymes and Coenzymes …
Pucotenlimab
Pucotenlimab is a recombinant humanized anti-PD-1 monoclonal antibody. It received its first global approval in China in July 2022 for the treatment of solid tumours. It is being investigated in other cancers.
Approved
Investigational
Matched Synonyms: … Immunoglobulin g4 (252-theronine,306-proline,432-alanine), anti-(human programmed cell death 1) (human-mus ... musculus monoclonal hx008 .gamma.4-chain), disulfide with human-mus musculus monoclonal hx008 .kappa …
Ragifilimab
Ragifilimab is under investigation in clinical trial NCT04225039 (Anti-gitr/anti-pd1/stereotactic Radiosurgery, in Recurrent Glioblastoma).
Investigational
Matched Synonyms: … Immunoglobulin g1 (de-448-lysine), anti-(human tumor necrosis factor receptor tnfrsf18) (human-mus musculus ... monoclonal incagn01876.gamma.1-chain), disulfide with human-mus musculus monoclonal incagn01876 .kappa …
Palifermin
Palifermin is a recombinant human keratinocyte growth factor (KGF). It is 140 residues long, and is produced using E. coli.
Palifermin was granted FDA approval on 15 December 2004.
Approved
Matched Synonyms: … 24-163 fibroblast growth factor 7 (human) …
Matched Description: … It is 140 residues long, and is produced using E. coli. ... Palifermin is a recombinant human keratinocyte growth factor (KGF). …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Matched Description: … It is 140 residues long, and is produced using E. coli. ... Palifermin is a recombinant human keratinocyte growth factor (KGF). …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
OptPA
Optimized tPA (OptPA; W253R/R275S-tPA) is an engineered variant of tPA designed to exhibit reduced neurotoxicity.
Investigational
Matched Synonyms: … Pptimized human tissue-type plasminogen activator …
CR002
CR002 is a novel investigational fully human monoclonal antibody that blocks the activity of excess platelet-derived growth factor-D (PDGF-D), a target shown to play a role in kidney inflammation. This is a novel therapeutic approach to treat kidney inflammation.
Investigational
Matched Synonyms: … Human monoclonal antibody against platelet-derived growth factor D …
Matched Description: … CR002 is a novel investigational fully human monoclonal antibody that blocks the activity of excess platelet-derived …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … CR002 is a novel investigational fully human monoclonal antibody that blocks the activity of excess platelet-derived …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Vestronidase alfa
Vestronidase alfa, or vestronidase alfa-vjbk, is a recombinant human lysosomal beta glucuronidase that is a purified enzyme produced by recombinant DNA technology in a Chinese hamster ovary cell line. The enzyme is a homotetramer consisted of 4 monomers with 629 amino acids, and holds the same amino acid sequence as...
Approved
Investigational
Matched Synonyms: … Recombinant human beta-glucuronidase …
Matched Description: … sequence as human beta-glucuronidase (GUS) [FDA Label]. ... Vestronidase alfa, or vestronidase alfa-vjbk, is a recombinant human lysosomal beta glucuronidase that ... spleen, heart valve abnormalities, and narrowed airways which can lead to lung infections and trouble …
Matched Categories: … Enzymes and Coenzymes ... Alimentary Tract and Metabolism …
Matched Description: … sequence as human beta-glucuronidase (GUS) [FDA Label]. ... Vestronidase alfa, or vestronidase alfa-vjbk, is a recombinant human lysosomal beta glucuronidase that ... spleen, heart valve abnormalities, and narrowed airways which can lead to lung infections and trouble …
Matched Categories: … Enzymes and Coenzymes ... Alimentary Tract and Metabolism …
Spheramine
Investigational
Matched Synonyms: … Allogeneic human retinal pigment epithelial cells on gelatin microcarriers …
Human Recombinant Bone Morphogenetic Protein 4
Investigational
Matched Synonyms: … RECOMBINANT HUMAN BONE MORPHOGENETIC PROTEIN 4 …
Matched Name: … Human Recombinant Bone Morphogenetic Protein 4 …
Matched Name: … Human Recombinant Bone Morphogenetic Protein 4 …
Lutikizumab
Lutikizumab is under investigation in clinical trial NCT02087904 (A Study Evaluating the Safety, Efficacy, and Pharmacodynamic Effects of ABT-981 in Patients With Knee Osteoarthritis).
Investigational
Matched Synonyms: … (synthetic human a-1234138 heavy chain), disulfide with synthetic human a-1234138 light chain, dimer …
Matched Description: … Lutikizumab is under investigation in clinical trial NCT02087904 (A Study Evaluating the Safety, Efficacy, and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … Lutikizumab is under investigation in clinical trial NCT02087904 (A Study Evaluating the Safety, Efficacy, and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Displaying drugs 1026 - 1050 of 1654 in total