Displaying drugs 10476 - 10500 of 12783 in total
AS-8112
AS-8112 is a synthetic compound that acts as a selective antagonist at the dopamine receptor subtypes D2 and D3, and the serotonin receptor 5-HT3. It has been shown to exert potent antiemetic effects in animal studies and has been investigated for potential medical use.
Experimental
Matched Iupac: … 5-bromo-N-[(6R)-1-ethyl-4-methyl-1,4-diazepan-6-yl]-2-methoxy-4-(methylamino)benzamide …
Matched Description: … acts as a selective antagonist at the dopamine receptor subtypes D2 and D3, and the serotonin receptor 5- …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Description: … acts as a selective antagonist at the dopamine receptor subtypes D2 and D3, and the serotonin receptor 5- …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Mericitabine
Mericitabine has been investigated for the treatment of Hepatitis C, Chronic.
Mericitabine is a polymerase inhibitor being developed for the treatment of chronic hepatitis C. Mericitabine is a prodrug of PSI-6130, which demonstrated excellent potency in preclinical studies. PSI-6130 is a pyrimidine nucleoside analog inhibitor of HCV RNA polymerase, an...
Investigational
Matched Iupac: … [(2R,3R,4R,5R)-5-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-4-fluoro-4-methyl-3-[(2-methylpropanoyl)oxy …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Entospletinib
Entospletinib has been used in trials studying the treatment of Oncology, Follicular Lymphoma, B-cell Malignancies, Mantle Cell Lymphoma, and Non-Hodgkin Lymphoma, among others.
Investigational
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Esreboxetine
Esreboxetine has been used in trials studying the treatment and basic science of Fibromyalgia.
Investigational
Matched Iupac: … (2S)-2-[(S)-(2-ethoxyphenoxy)(phenyl)methyl]morpholine …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Etanidazole
Etanidazole has been used in trials studying the diagnostic of Adult Ependymoma, Malignant Ascites, Adult Gliosarcoma, Adult Mixed Glioma, and Adult Glioblastoma, among others.
Investigational
Matched Iupac: … N-(2-hydroxyethyl)-2-(2-nitro-1H-imidazol-1-yl)acetamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Apricitabine
Apricitabine has been used in trials studying the treatment of HIV Infections.
Investigational
Matched Iupac: … 4-amino-1-[(2R,4R)-2-(hydroxymethyl)-1,3-oxathiolan-4-yl]-1,2-dihydropyrimidin-2-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
LY-2334737
LY2334737 has been used in trials studying the treatment of Solid Tumor, Metastatic Tumor, and Malignant Solid Tumor.
Investigational
Matched Iupac: … N-{1-[(2R,4R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-2-oxo-1,2-dihydropyrimidin-4-yl …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Cinepazet
Experimental
Matched Iupac: … ethyl 2-{4-[(2E)-3-(3,4,5-trimethoxyphenyl)prop-2-enoyl]piperazin-1-yl}acetate …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Fluzoparib
Fluzoparib is under investigation in clinical trial NCT03863860 (A Trial of Maintenance Treatment With Fluzoparib Versus Placebo in Relapsed Ovarian Cancer Patients).
Investigational
Matched Iupac: … trifluoromethyl)-5H,6H,7H,8H-[1,2,4]triazolo[1,5-a]pyrazine-7-carbonyl]phenyl}methyl)-1,2-dihydrophthalazin-1- …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Monophosphothiamine
Experimental
Matched Iupac: … 3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-4-methyl-5-[2-(phosphonooxy)ethyl]-1,3-thiazol-3-ium chloride …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Revaprazan
Revaprazan is under investigation in clinical trial NCT01750437 (Phase 2 Clinical Trial to Investigate the Safety, Tolerability and Efficacy of YH1885L in Patients With Non-erosive Reflux Disease(nerd)).
Investigational
Matched Iupac: … N-(4-fluorophenyl)-4,5-dimethyl-6-(1-methyl-1,2,3,4-tetrahydroisoquinolin-2-yl)pyrimidin-2-amine …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
4-(2,4-Dimethyl-Thiazol-5-Yl)-Pyrimidin-2-Ylamine
Experimental
Matched Name: … 4-(2,4-Dimethyl-Thiazol-5-Yl)-Pyrimidin-2-Ylamine …
Matched Iupac: … 4-(2,4-dimethyl-1,3-thiazol-5-yl)pyrimidin-2-amine …
Matched Iupac: … 4-(2,4-dimethyl-1,3-thiazol-5-yl)pyrimidin-2-amine …
3,5,6,8-Tetramethyl-N-Methyl Phenanthrolinium
Experimental
Matched Iupac: … 1,3,5,6,8-pentamethyl-1,10-phenanthrolin-1-ium …
4-(Cytidine 5'-diphospho)-2-C-methyl-D-erythritol
Experimental
Matched Name: … 4-(Cytidine 5'-diphospho)-2-C-methyl-D-erythritol …
Matched Iupac: … {[(2R,3S,4R,5R)-3,4-dihydroxy-5-(2-hydroxy-4-imino-1,4-dihydropyrimidin-1-yl)oxolan-2-yl]methoxy}({hydroxy …
Matched Iupac: … {[(2R,3S,4R,5R)-3,4-dihydroxy-5-(2-hydroxy-4-imino-1,4-dihydropyrimidin-1-yl)oxolan-2-yl]methoxy}({hydroxy …
4-[(5-bromopyridin-2-yl)amino]-4-oxobutanoic acid
Experimental
Matched Name: … 4-[(5-bromopyridin-2-yl)amino]-4-oxobutanoic acid …
Matched Iupac: … 3-[(5-bromopyridin-2-yl)carbamoyl]propanoic acid …
Matched Iupac: … 3-[(5-bromopyridin-2-yl)carbamoyl]propanoic acid …
Polyhexamethyleneguanidine
Investigational
Exon 45 specific phosphorothioate oligonucleotide
Investigational
Carfentanil
Carfentanil or carfentanyl (Wildnil) is an analogue of the popular synthetic opioid analgesic fentanyl, and is one of the most potent opioids known (also the most potent opioid used commercially). Carfentanil was first synthesized in 1974 by a team of chemists at Janssen Pharmaceutica which included Paul Janssen. It has...
Illicit
Investigational
Vet approved
Matched Iupac: … methyl 1-(2-phenylethyl)-4-(N-phenylpropanamido)piperidine-4-carboxylate …
Matched Description: … 10,000 times that of morphine and 100 times that of fentanyl, with activity in humans starting at about 1 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Description: … 10,000 times that of morphine and 100 times that of fentanyl, with activity in humans starting at about 1 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Batroxobin
Batroxobin is a defibrinogenating hemostatic agent derived from the venom of a pit viper, Bothrops atrox moojeni. In addition to batroxobin, the venom of Bothrops atrox has a composition of 10.2% neutral carbohydrate. Batroxobin is a serine protease, which cleaves the 16 Arginine - 17 Glycine bond in fibrinogen. The...
Experimental
Matched Description: … The MW of batroxobin is approximately 43,000 g/mol-1, and it contains 231 amino acids. …
Chlorfenson
Chlorfenson is developed by Moberg Derma for the treatment of onychomycosis (nail fungus) as the primary indication.
Investigational
Matched Iupac: … 4-chlorophenyl 4-chlorobenzene-1-sulfonate …
2'-Deoxyuridine 5'-alpha,beta-imido-triphosphate
Experimental
Matched Name: … 2'-Deoxyuridine 5'-alpha,beta-imido-triphosphate …
Matched Iupac: … ({[({[(2R,3S,5R)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-3-hydroxyoxolan-2-yl]methoxy}(hydroxy …
Matched Iupac: … ({[({[(2R,3S,5R)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-3-hydroxyoxolan-2-yl]methoxy}(hydroxy …
Displaying drugs 10476 - 10500 of 12783 in total