Displaying drugs 10476 - 10500 of 12327 in total
Siagoside
Siagoside (Sygen, AGF 2) has been investigated for the treatment of Parkinson Disease. It is a naturally occurring substance in the nerve cell’s membrane that is thought to play a role in cell growth, development, and repair. Siagoside completed phase 2 trials for parkinson's disease (PD) treatment. Sygen appears to...
Investigational
Matched Iupac: … N-[(2S,3R,4E)-1-{[(2R,3R,4R,5S,6R)-5-[(2S,4S,4'aR,5R,5'S,6R,7'R,8'S,8'aS)-5-acetamido-8'-{[(2S,3R,4R, …
Fasudil
Fasudil has been investigated in Carotid Stenosis.
Investigational
Matched Iupac: … 5-(1,4-diazepane-1-sulfonyl)isoquinoline …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Dithiazanine
Dithiazanine is a highly potent anthelmintic, introduced in 1959 for the treatment of strongyloid worms and whipworms. However, its use is severely limited due to its toxicity. Dithiazanine iodide was associated with eight fatal cases of severe acidosis and shock between 1961 and 1964. Dithiazanine iodide has been withdrawn from...
Vet approved
Withdrawn
Matched Iupac: … 3-ethyl-2-[5-(3-ethyl-2,3-dihydro-1,3-benzothiazol-2-ylidene)penta-1,3-dien-1-yl]-1,3-benzothiazol-3- …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Sagopilone
Sagopilone has been used in trials studying the treatment of Melanoma, Neoplasms, CNS Disease, Breast Cancer, and Breast Neoplasms, among others. It is a so-called fully synthetic epothilone and is the first such compound to be in clinical development to combat several forms of cancer. Epothilones are 16-member ring macrolides...
Investigational
Matched Iupac: … ,11S,12S,16R)-7,11-dihydroxy-8,8,12,16-tetramethyl-3-(2-methyl-1,3-benzothiazol-5-yl)-10-(prop-2-en-1- …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Irsogladine
Irsogladine is under investigation in clinical trial NCT02581696 (The Drug-drug Interaction and Safety of Lafutidine and Irsogladine Maleate in Healthy Adult Volunteers).
Investigational
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Phenoperidine
Experimental
Matched Iupac: … ethyl 1-(3-hydroxy-3-phenylpropyl)-4-phenylpiperidine-4-carboxylate …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Cefozopran
Experimental
Matched Iupac: … -1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl}imidazo[1,2-b]pyridazin-1-ium ... 1-{[(6R,7R)-7-[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-(methoxyimino)acetamido]-2-carboxy-8-oxo-5-thia …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
GC-376 free acid
GC-376 is a 3C-like protease (3CLpro or Mpro) inhibitor that stops the cleavage and activation of functional viral proteins required for replication and transcription in host cells . The compound is known as a direct acting antiviral (DAA) for coronaviruses, and was initially developed using structure-guided design to combat MERS-Cov...
Experimental
Matched Iupac: … -1-sulfonic acid ... (2S)-2-[(2S)-2-{[(benzyloxy)carbonyl]amino}-4-methylpentanamido]-1-hydroxy-3-(2-oxopyrrolidin-3-yl)propane …
Matched Description: … GC-376 is a 3C-like protease (3CLpro or Mpro) inhibitor that stops the cleavage ... A prodrug of [GC-373], GC-376 has recently been used to test inhibition of SARS-Cov-2 Mpro ... addition, GC-376 displays potent activity against various coronaviruses such as feline, ferret, and mink M< …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Description: … GC-376 is a 3C-like protease (3CLpro or Mpro) inhibitor that stops the cleavage ... A prodrug of [GC-373], GC-376 has recently been used to test inhibition of SARS-Cov-2 Mpro ... addition, GC-376 displays potent activity against various coronaviruses such as feline, ferret, and mink M< …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
9-(3-IODOBENZYLAMINO)-1,2,3,4-TETRAHYDROACRIDINE
Experimental
Sodium dichloroacetate
Investigational
Sulfachlorpyridazine
A sulfonamide antimicrobial used for urinary tract infections and in veterinary medicine.
Vet approved
Matched Iupac: … 4-amino-N-(6-chloropyridazin-3-yl)benzene-1-sulfonamide …
Amineptine
The Food and Drug Administration suspended the marketing authorisation for Survector in 1999 and France withdrew it from the market, however several developing countries continued to produce it up until 2005.
Illicit
Withdrawn
Matched Iupac: … 7-({tricyclo[9.4.0.0^{3,8}]pentadeca-1(15),3,5,7,11,13-hexaen-2-yl}amino)heptanoic acid …
1,4-Dideoxy-5-Dehydro-O2-Sulfo-Glucuronic Acid
Experimental
3-AMINO-3-BENZYL-[4.3.0]BICYCLO-1,6-DIAZANONAN-2-ONE
Experimental
Matched Iupac: … 2-({5,6-diphenyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl}amino)ethan-1-ol …
4-hydroxybenzyl coenzyme A
Experimental
5-monophosphate-9-beta-D-ribofuranosyl xanthine
Experimental
Adenosine-5'-[Beta, Gamma-Methylene]Triphosphate
Experimental
2-(3'-Methoxyphenyl) Benzimidazole-4-Carboxamide
Experimental
Astragalus mongholicus root polysaccharides
Investigational
Ectoine
Ectoine is under investigation in clinical trial NCT03186755 (Clinical Evaluation of Hylo-dual Versus Patanol in Children With Seasonal Allergic Conjunctivitis).
Investigational
Displaying drugs 10476 - 10500 of 12327 in total