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Displaying drugs 10576 - 10600 of 12990 in total
Fresolimumab has been used in trials studying the treatment of Primary Brain Tumors, Metastatic Breast Cancer, Diffuse Systemic Sclerosis, Pleural Malignant Mesothelioma, and Primary Focal Segmental Glomerulosclerosis.
Investigational
Halofuginone is a low molecular weight quinazolinone alkaloid, and a potent inhibitor of collagen alpha1(I) and matrix metalloproteinase 2 (MMP-2) gene expression. Halofuginone also effectively suppresses tumor progression and metastasis in mice. Collgard Biopharmaceuticals is developing halofuginone for the treatment of scleroderma and received orphan drug designation from the U.S....
Investigational
Vet approved
Matched Synonyms: … (+/-)-trans-7-bromo-6-chloro-3-(3-(3-hydroxy-2-piperidyl)-acetonyl)-4(3H)-quinazolinone …
Matched Iupac: … 7-bromo-6-chloro-3-{3-[(2R,3S)-3-hydroxypiperidin-2-yl]-2-oxopropyl}-3,4-dihydroquinazolin-4-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
B38-CAP is structured as a carboxypeptidase and derived from Paenibacillus sp. The molecule, an Angiotensin Converting Enzyme 2 (ACE2)-like enzyme, shares structural similarities to the mammalian ACE2. B38-CAP is an ACE2-like enzyme which decreases angiotensin II levels. It is being investigated for treating hypertension, myocardial fibrosis, and cardiac dysfunction.
Investigational
Phthalocyanine is under investigation in clinical trial NCT00103246 (Photodynamic Therapy Using Silicon Phthalocyanine 4 in Treating Patients With Actinic Keratosis, Bowen's Disease, Skin Cancer, or Stage I or Stage II Mycosis Fungoides).
Investigational
Matched Iupac: … 2,11,20,29,37,38,39,40-octaazanonacyclo[28.6.1.1³,¹⁰.1¹²,¹⁹.1²¹,²⁸.0⁴,⁹.0¹³,¹⁸.0²²,²⁷.0³¹,³⁶]tetraconta …
Matched Description: … under investigation in clinical trial NCT00103246 (Photodynamic Therapy Using Silicon Phthalocyanine 4
Vesencumab is under investigation in clinical trial NCT00747734 (A Study of MNRP1685A in Patients With Locally Advanced or Metastatic Solid Tumors).
Investigational
Matched Categories: … Neuropilin-1
Experimental
Matched Name: … 2-Amino-4-(2-Amino-Ethoxy)-Butyric Acid …
Matched Iupac: … (2S)-2-amino-4-(2-aminoethoxy)butanoic acid …
Experimental
Matched Iupac: … 5-methyl-1,2,3,4-tetrahydroisoquinolin-1-one …
Golvatinib has been investigated for the treatment of Platinum-Resistant Squamous Cell Carcinoma of the Head and Neck.
Investigational
Matched Iupac: … N'1-{2-fluoro-4-[(2-{[4-(4-methylpiperazin-1-yl)piperidine-1-carbonyl]amino}pyridin-4-yl)oxy]phenyl}- ... N1-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Ribose is under investigation in clinical trial NCT01727479 (Ribose and Sport Performance).
Investigational
Investigational
Matched Synonyms: … 4-((l-valyl)oxy)butanoic acid …
Matched Iupac: … 4-{[(2S)-2-amino-3-methylbutanoyl]oxy}butanoic acid …
2'-Fucosyllactose is under investigation in clinical trial NCT03847467 (Pilot and Feasibility Study of 2'-FL as a Dietary Supplement in IBD Patients Receiving Stable Maintenance Anti-tnf Therapy).
Investigational
Matched Iupac: … (2R,3R,4R,5R)-4-{[(2S,3R,4S,5R,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-{[(2S,3S,4R,5S,6S)-3,4,5-trihydroxy …
A glucocorticoid with the general properties of corticosteroids. It has been used by mouth in the treatment of all conditions in which corticosteroid therapy is indicated except adrenal-deficiency states for which its lack of sodium-retaining properties makes it less suitable than hydrocortisone with supplementary fludrocortisone. (From Martindale, The Extra Pharmacopoeia,...
Experimental
Matched Iupac: … (1R,2R,3aS,3bS,5S,9aR,9bS,10S,11aS)-5-fluoro-1,10-dihydroxy-1-(2-hydroxyacetyl)-2,9a,11a-trimethyl-1H …
Experimental
Matched Iupac: … }sulfonyl)amino]-2-[2-(methylsulfanyl)ethyl]ethan-1-one ... (2S)-2-amino-1-[({[(2R,3S,4R,5R)-5-(6-amino-4,9-dihydro-1H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy …
Investigational
Matched Iupac: … 31.2.2.2^{3,6}.2^{8,11}.2^{13,16}.2^{18,21}.2^{23,26}.2^{28,31}]nonatetracontan-5-yl]methoxy}butane-1- ... hexasodium 4-{[(1S,3R,5R,6S,8R,10R,11S,13R,15R,16S,18R,20R,21S,23R,25R,26S,28R,30R,31S,33R,35R,36R,37R ... 36,37,38,39,40,41,42,43,44,45,46,47,48,49-tetradecahydroxy-35-(hydroxymethyl)-10,15,20,25,30-pentakis[(4- …
Experimental
Displaying drugs 10576 - 10600 of 12990 in total