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Displaying drugs 10701 - 10725 of 12517 in total
Experimental
Matched Iupac: … {[(3R)-4-[(2R,3R,4R)-3,4-dihydroxy-2-(hydroxymethyl)pyrrolidin-1-yl]-1,3-dihydroxybutan-2-yl]oxy}-lambda4 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Experimental
Matched Iupac: … (2E,4R,5S,6E)-3,5-dimethoxy-4-methyl-7-(2-{2-[(2S,3E,5E)-7-methylocta-3,5-dien-2-yl]-1,3-thiazol-4-yl …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
An alkaloid that has actions similar to nicotine on nicotinic cholinergic receptors but is less potent. It has been proposed for a variety of therapeutic uses including in respiratory disorders, peripheral vascular disorders, insomnia, and smoking cessation. [PubChem]
Investigational
Matched Iupac: … 2-[(2R,6S)-6-[(2S)-2-hydroxy-2-phenylethyl]-1-methylpiperidin-2-yl]-1-phenylethan-1-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Investigational
Matched Iupac: … N-(3,3-dimethyl-2,3-dihydro-1H-indol-6-yl)-2-{[(pyridin-4-yl)methyl]amino}pyridine-3-carboxamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …
Nimorazole has been used in trials studying the treatment of Hypoxia, Radiotherapy, Hypoxic Modification, Gene Profile, Gene Signature, and Head and Neck Squamous Cell Carcinoma, among others.
Investigational
Matched Iupac: … 4-[2-(5-nitro-1H-imidazol-1-yl)ethyl]morpholine …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
TAK-901 has been used in trials studying the treatment of Lymphoma, Myelofibrosis, Multiple Myeloma, Myeloid Metaplasia, and Advanced Solid Tumors, among others.
Investigational
Matched Iupac: … 5-[3-(ethanesulfonyl)phenyl]-3,8-dimethyl-N-(1-methylpiperidin-4-yl)-9H-pyrido[2,3-b]indole-7-carboxamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …
Investigational
Matched Iupac: … (1R,10S)-8-oxatetracyclo[8.7.0.0^{2,7}.0^{12,17}]heptadeca-2(7),3,5,12,14,16-hexaene-5,6,10,14,15-pentol …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …
Receptor binding domain SARS-CoV-2 Hepatitis B surface antigen virus-like particle vaccine (RBD SARS-CoV-2 HBsAg VLP vaccine), is a virus-like particle vaccine candidate where the RBD antigen is conjugated to the hepatitis B surface antigen . Virus-like particles (VLPs) are protein-based vaccines that stimulate high immune responses because of the VLPs’...
Investigational
Matched Synonyms: … RBD SARS-CoV-2 HBsAg VLP vaccine …
Matched Name: … Receptor binding domain (RBD) SARS-CoV-2 (COVID-19) hepatitis B surface antigen (HBsAg) virus-like particle …
Matched Description: … Receptor binding domain SARS-CoV-2 Hepatitis B surface antigen virus-like particle vaccine (RBD SARS-CoV ... -2 HBsAg VLP vaccine), is a virus-like particle vaccine candidate where the RBD antigen is conjugated …
Experimental
Matched Name: … N-(3-AMINOPROPYL)-2-NITROBENZENAMINE …
Matched Iupac: … N1-(2-nitrophenyl)propane-1,3-diamine …
Experimental
Matched Synonyms: … Salicylic acid, methyl ester, 2-ethylbutyrate …
Matched Name: … Methyl salicylate 2-ethylbutyrate …
Matched Iupac: … methyl 2-[(2-ethylbutanoyl)oxy]benzoate …
Experimental
Matched Name: … 4-(2-AMINOPHENYL)-4-OXOBUTANOIC ACID …
Matched Iupac: … 4-(2-aminophenyl)-4-oxobutanoic acid …
Remikiren is an orally active, high specificity renin inhibitor.
Experimental
Matched Iupac: … -3,4-dihydroxybutan-2-yl]-3-(1H-imidazol-5-yl)propanamide ... (2S)-2-[(2S)-2-benzyl-3-(2-methylpropane-2-sulfonyl)propanamido]-N-[(2S,3R,4S)-1-cyclohexyl-4-cyclopropyl …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
PH-797804 has been investigated for the treatment of Osteoarthritis.
Investigational
Matched Iupac: … 3-{3-bromo-4-[(2,4-difluorophenyl)methoxy]-6-methyl-2-oxo-1,2-dihydropyridin-1-yl}-N,4-dimethylbenzamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Ricolinostat is under investigation for the treatment of Breast Carcinoma and Metastatic Breast Cancer.
Investigational
Matched Iupac: … 7-{[2-(diphenylamino)pyrimidin-5-yl]formamido}-N-hydroxyheptanamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
GC-373 is a peptide aldehyde which is metabolized from the bisulfide adduct, GC-376 free acid[A219031,A219036]. It is an inhibitor of Mpro (otherwise known as 3CLpro), a viral encoded protease that cleaves and activates functional proteins involved in viral replication and transcription . GC-373 has been shown to inhibit the Mpro...
Experimental
Matched Iupac: … benzyl N-[(1S)-3-methyl-1-{[(2S)-1-oxo-3-(2-oxopyrrolidin-3-yl)propan-2-yl]carbamoyl}butyl]carbamate …
Matched Description: … with its prodrug, GC-376, GC-373 was recently investigated _in vitro_ in cell culture against SARS-Cov-2
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Phenothiazine (PTZ) is an organic thiazine compound.
Experimental
Vet approved
Tifuvirtide is the first members of a new class of anti-HIV drugs which is also called fusion inhibitors. It has received fast-track designation from the FDA and is in Phase I/II clinical testing.
Investigational
A synthetic nonapeptide comprising cysteinyl, phenylalanyl, phenylalanyl, glutaminyl, asparaginyl, cysteinyl, prolyl, lysyl, and glycinamide residues in sequence, with a disulfide bridge joining the two cysteine residues. Its antidiuretic effects are less than those of vasopressin. It is a non-catecholamine vasoconstrictor used in local anaesthetic injections for dental use, and is...
Experimental
Matched Synonyms: … PLV-2 ... 2-(L-phenylalanine)-8-L-lysinevasopressin …
Ethylmercurithiosalicylic acid is a topical antiseptic used on skin and mucous membranes. It is also used as a preservative in pharmaceuticals.
Experimental
Matched Synonyms: … 2-(ethylmercuri-thio)-benzoic acid ... 2-(ethylmercuriothio)benzoic acid …
Matched Iupac: … [(2-carboxyphenyl)sulfanyl](ethyl)mercury …
Three paclitaxel molecules linked by a cleavable succinyl ester linkage to a brain peptide vector, Angiopep-2, conjugate named ANG1005.
Investigational
Matched Synonyms: … [a-N-(2'succinyl-paclitaxel)Thr]-Phe-Phe-Tyr-Gly-Gly-Ser-Arg-Gly-[epsilon-N-(2'succinyl-paclitaxel)Lys ... ]-Arg-Asn-Asn-Phe-[epsilon-N-(2'succinyl-paclitaxel)Lys]-Thr-Glu-Glu-Tyr …
Matched Description: … paclitaxel molecules linked by a cleavable succinyl ester linkage to a brain peptide vector, Angiopep-2, …
Investigational
Matched Synonyms: … Methyl 4-{[2-(acetamino)ethyl]sulfanyl}-4-oxobutanoate ... Butanoic acid, 4-[[2-(acetylamino)ethyl]thio]-4-oxo-, methyl ester …
Matched Iupac: … methyl 4-[(2-acetamidoethyl)sulfanyl]-4-oxobutanoate …
Ocrylate is under investigation in clinical trial NCT01918059 (Cosmetic Outcome Study of Lid Laceration Repair With Suture Versus Tissue Adhesive).
Investigational
Matched Synonyms: … OCTYL-2-CYANOACRYLATE …
Matched Iupac: … octyl 2-cyanoprop-2-enoate …
Pyrazoloacridine has been used in trials studying the treatment of Lung Cancer, Liver Cancer, Breast Cancer, Melanoma (Skin), and Metastatic Cancer, among others.
Investigational
Matched Iupac: … (3-{4-methoxy-10-nitro-8,14,15-triazatetracyclo[7.6.1.0^{2,7}.0^{13,16}]hexadeca-1(15),2,4,6,9(16),10,12 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Displaying drugs 10701 - 10725 of 12517 in total