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Displaying drugs 10776 - 10800 of 12992 in total
Zalypsis
Zalypsis has been used in trials studying the treatment of Lymphoma, Solid Tumors, Ewing's Sarcoma, Endometrial Cancer, and Uterine Cervical Cancer, among others.
Investigational
Matched Iupac: … enamido]methyl}-8,10-dioxa-14,24-diazahexacyclo[14.7.1.0^{2,14}.0^{4,12}.0^{7,11}.0^{18,23}]tetracosa-4( …
2-(2-Hydroxy-1,1-Dihydroxymethyl-Ethylamino)-Ethanesulfonic Acid
Experimental
Matched Iupac: … 2-{[1,3-dihydroxy-2-(hydroxymethyl)propan-2-yl]amino}ethane-1-sulfonic acid …
Neoantigen specific TCR-T cell therapy
Investigational
Inolimomab
Inolimomab is under investigation as an agent to treat steroid-resistant graft vs host disease. It has thus far offered similar efficacy to other monoclonal antibody options, though it may carry a higher risk of infections.
Investigational
4-Hydroxy-L-Threonine-5-Monophosphate
Experimental
Matched Name: … 4-Hydroxy-L-Threonine-5-Monophosphate …
Matched Iupac: … (2S,3S)-2-amino-3-hydroxy-4-(phosphonooxy)butanoic acid …
Matched Iupac: … (2S,3S)-2-amino-3-hydroxy-4-(phosphonooxy)butanoic acid …
2,6-dimethyl-4-[(E)-2-phenylethenyl]phenol
Experimental
Matched Name: … 2,6-dimethyl-4-[(E)-2-phenylethenyl]phenol …
Matched Iupac: … 2,6-dimethyl-4-[(1E)-2-phenylethenyl]phenol …
Matched Iupac: … 2,6-dimethyl-4-[(1E)-2-phenylethenyl]phenol …
4-(2,2,2-TRIFLUOROETHYL)-L-PHENYLALANINE
Experimental
Matched Name: … 4-(2,2,2-TRIFLUOROETHYL)-L-PHENYLALANINE …
Matched Iupac: … (2S)-2-amino-3-[4-(2,2,2-trifluoroethyl)phenyl]propanoic acid …
Matched Iupac: … (2S)-2-amino-3-[4-(2,2,2-trifluoroethyl)phenyl]propanoic acid …
4-(2-METHOXYPHENYL)-2-OXOBUT-3-ENOIC ACID
Experimental
Matched Name: … 4-(2-METHOXYPHENYL)-2-OXOBUT-3-ENOIC ACID …
Matched Iupac: … (3Z)-4-(2-methoxyphenyl)-2-oxobut-3-enoic acid …
Matched Iupac: … (3Z)-4-(2-methoxyphenyl)-2-oxobut-3-enoic acid …
Poliglusam
Poliglusam, or chitosan, is a linear polysaccharide consisting of D-glucosamine and N-acetyl-D-glucosamine. Naturally-occuring poliglusam is found in the cell walls of fungi, soil and sediments where it is produced from degradation of chitin induced by certain groups of bacteria that produce the enzymes deacetylase or chitosanase enzymes . In comparison,...
Experimental
Luteolin
Experimental
Matched Iupac: … 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Tosylchloramide
Tosylchloramide, also known as chloramine-T, is a chlorinated and deprotonated sulfonamide used as a mild disinfectant. It is not stable in the water dissolved form.
Experimental
Matched Iupac: … N-chloro-4-methylbenzene-1-sulfonamide …
Matched Salts cas: … 127-65-1 ... 7080-50-4 …
Matched Salts cas: … 127-65-1 ... 7080-50-4 …
AMP-201
AMP-201 comprises an adeno-associated virus type 8 vector (AAV8) encoding the collagen Q gene (COLQ). It is under investigation for the treatment of collagen Q congenital myasthenia.
Investigational
5R-(3,4-DICHLOROPHENYLMETHYL)-3-(2-THIOPHENESULFONYLAMINO)-4-OXO-2-THIONOTHIAZOLIDINE
Experimental
Matched Name: … 5R-(3,4-DICHLOROPHENYLMETHYL)-3-(2-THIOPHENESULFONYLAMINO)-4-OXO-2-THIONOTHIAZOLIDINE …
Matched Iupac: … N-[(5R)-5-[(3,4-dichlorophenyl)methyl]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]thiophene-2-sulfonamide …
Matched Iupac: … N-[(5R)-5-[(3,4-dichlorophenyl)methyl]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]thiophene-2-sulfonamide …
Muplestim
Muplestim is under investigation in clinical trial NCT00002258 (A Phase I, Open Label Trial to Evaluate the Safety, Tolerance and Biological Effects of SDZ ILE-964 (Recombinant Human Interleukin-3, RhIL-3) in HIV Infected Patients With Cytopenia).
Investigational
Rexin G
Rexin-G is a tumor-targeted, injectable retroviral vector carrying a mutant form of the cyclin G1 gene. It is under development by Epeius Biotechnologies for the potential treatment of metastatic cancer. It is also being investigated for preventing SARSCOV-2 viral entry.
Investigational
LGD2941
LGD2941 is a non-steroidal, selective androgen receptor modulator (SARM) developed jointly by Ligand and TAP.
Investigational
Matched Iupac: … 6-[(2R,5R)-2-methyl-5-[(1R)-2,2,2-trifluoro-1-hydroxyethyl]pyrrolidin-1-yl]-4-(trifluoromethyl)-1,2-dihydroquinolin …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Ocinaplon
Investigational
Matched Iupac: … 4-[3-(pyridine-2-carbonyl)pyrazolo[1,5-a]pyrimidin-7-yl]pyridine …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Cutamesine
Investigational
Matched Iupac: … 1-[2-(3,4-dimethoxyphenyl)ethyl]-4-(3-phenylpropyl)piperazine …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Galunisertib
Galunisertib has been used in trials studying the basic science and treatment of Glioma, Neoplasms, Solid Tumor, GLIOBLASTOMA, and Prostate Cancer, among others.
Investigational
Matched Iupac: … 4-[2-(6-methylpyridin-2-yl)-4H,5H,6H-pyrrolo[1,2-b]pyrazol-3-yl]quinoline-6-carboxamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Figopitant
Figopitant is under investigation in clinical trial NCT02209714 (Safety, Tolerability and Pharmacodynamics After Oral Administration of BIIF 1149 BS in Healthy Male Volunteers).
Investigational
Matched Iupac: … (2S)-N-{2-[3,5-bis(trifluoromethyl)phenyl]ethyl}-2-[4-(cyclopropylmethyl)piperazin-1-yl]-N-methyl-2-phenylacetamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Domiodol
Experimental
Matched Iupac: … [2-(iodomethyl)-1,3-dioxolan-4-yl]methanol …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Milciclib Maleate
Milciclib Maleate is under investigation in clinical trial NCT01301391 (Study of Oral PHA-848125AC in Patients With Malignant Thymoma Previously Treated With Multiple Lines of Chemotherapy).
Investigational
Matched Iupac: … N,1,4,4-tetramethyl-8-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-1H,4H,5H-pyrazolo[4,3-h]quinazoline-3 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Xylazine
Xylazine is a clonidine analog used as a non-opioid tranquilizer in veterinary medicine and as an emetic, especially in cats.[A9095,L42675,A251420] It acts as an agonist at α2 adrenoceptors; however, its affinity is lower than the one reported for other α2 adrenergic receptor agonists such as detomidine and medetomidine. Xylazine is...
Vet approved
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Displaying drugs 10776 - 10800 of 12992 in total