Displaying drugs 10776 - 10800 of 11800 in total
KAI-1455
KAI-1455 is a selective epsilon protein kinase C (εPKC) activator designed to reduce ischemic organ injury during procedures where blood supply may be compromised, such as coronary artery bypass grafting (CABG), congenital cardiac defect repair, and hip replacement and may protect against renal injury associated with contrast media. Several studies...
Investigational
Matched Description: … KAI-1455 is a selective epsilon protein kinase C (εPKC) activator designed to reduce ischemic organ injury ... Several studies have demonstrated that epsilon PKC plays a key role in cytoprotection during periods ... In preclinical studies, KAI-1455 showed a dramatic reduction in infarct size when delivered prior to …
Rosemary
Rosemary is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Description: … Rosemary is a plant/plant extract used in some OTC (over-the-counter) products. …
Ipafricept
Ipafricept is under investigation in clinical trial NCT01608867 (A Dose Escalation Study of OMP-54F28 in Subjects With Solid Tumors).
Investigational
Matched Description: … Ipafricept is under investigation in clinical trial NCT01608867 (A Dose Escalation Study of OMP-54F28 …
Hemoporfin
Hemoporfin is under investigation in clinical trial NCT03125057 (A Pilot Study of Hemoporfin PDT in Children With Port-wine Stain).
Investigational
Matched Description: … Hemoporfin is under investigation in clinical trial NCT03125057 (A Pilot Study of Hemoporfin PDT in Children …
Orelabrutinib
Orelabrutinib is under investigation in clinical trial NCT04305197 (A Study of ICP-022 in Patients With Systemic Lupus Erythematosus (SLE)).
Investigational
Matched Description: … Orelabrutinib is under investigation in clinical trial NCT04305197 (A Study of ICP-022 in Patients With …
DCVax-L
DCVax-L is a personalized immunotherapy comprising an autologous vaccine with dendritic cells loaded in vitro with autologous tumour lysate.
Investigational
Matched Description: … DCVax-L is a personalized immunotherapy comprising an autologous vaccine with dendritic cells loaded …
DTx-1252
DTx-1252 is a siRNA therapeutic under investigation for the treatment of Charcot-Marie-Tooth Disease type 1A (CMTD1A).
Investigational
Matched Description: … DTx-1252 is a siRNA therapeutic under investigation for the treatment of Charcot-Marie-Tooth Disease …
Etavopivat
Etavopivat is a small molecule activator of erythrocyte pyruvate kinase (PKR) under investigation for the treatment of sickle cell disease.
Investigational
Matched Description: … Etavopivat is a small molecule activator of erythrocyte pyruvate kinase (PKR) under investigation for …
CLBS12
CLBS12 is a GCSF-mobilized autologous cell therapy derived from CD34+ cells being investigated for the treatment of Buerger’s disease.
Investigational
Matched Description: … CLBS12 is a GCSF-mobilized autologous cell therapy derived from CD34+ cells being investigated for the …
UV1
UV1 is a cancer vaccine consisting of p719-20, p728, and p725 synthetic peptides representing fragments of the hTERT subunit
Investigational
Matched Description: … UV1 is a cancer vaccine consisting of p719-20, p728, and p725 synthetic peptides representing fragments …
mRNA-3745
mRNA-3745 is a lipid nanoparticle (LNP) encapsulated with nucleoside-modified, codon-optimized mRNAs encoding human glucose 6-phosphatase (G6Pase).
Investigational
Matched Description: … mRNA-3745 is a lipid nanoparticle (LNP) encapsulated with nucleoside-modified, codon-optimized mRNAs …
JNJ-55308942
JNJ-55308942 is under investigation in clinical trial NCT05328297 (A Study of JNJ-55308942 in the Treatment of Bipolar Depression).
Investigational
Matched Description: … JNJ-55308942 is under investigation in clinical trial NCT05328297 (A Study of JNJ-55308942 in the Treatment …
Thioproperazine
Thioproperazine is a potent neuroleptic with antipsychotic properties. Thioproperazine has a marked cataleptic and antiapomorphine activity associated with relatively slight sedative, hypothermic and spasmolytic effects. It is virtually without antiserotonin and hypotensive action and has no antihistaminic property. It is used for the treatment of all types of acute and...
Experimental
Matched Description: … Thioproperazine is a potent neuroleptic with antipsychotic properties. ... Thioproperazine has a marked cataleptic and antiapomorphine activity associated with relatively slight …
V1003
V1003 is an intranasal formulation of buprenorphine, an opiate analgesic, for the management of post-operative pain in hospital and home settings. Buprenorphine is a well-known analgesic and the intranasal formulation has the potential to provide a convenient alternative to other treatments, allowing patients to manage their post-operative pain both prior...
Investigational
Matched Description: … Buprenorphine is a well-known analgesic and the intranasal formulation has the potential to provide a …
DG051
DG051 is a novel small-molecule inhibitor of leukotriene A4 hydrolase (LTA4H), the protein made by one of the genes in the leukotriene pathway that has been shown to link to risk of heart attack. DG051 is designed to decrease risk of heart attack by decreasing the production of leukotriene B4...
Investigational
Matched Description: … DG051 is a novel small-molecule inhibitor of leukotriene A4 hydrolase (LTA4H), the protein made by one ... by decreasing the production of leukotriene B4 (LTB4), an end product of the leukotriene pathway and a …
Guvacine
Guvacine is a pyridine alkaloid found in the Areca nut (also known as the Betel nut). It is an experimental drug with no approved indication. Experimental studies are still being investigated to determine all of the physiological effects and mechanisms of action of guvacine. Currently it has been determined that...
Experimental
Matched Description: … Guvacine is a pyridine alkaloid found in the Areca nut (also known as the Betel nut). ... Currently it has been determined that guvacine is a specific GABA reuptake inhibitor with no significant …
BacTRL-spike
BacTRL-Spike is composed of a bacterial medium with colony-forming-units of live Bifidobacterium longum engineered to deliver synthetic DNA encoding spike protein from SARS-CoV-2 contained by plasmids. The vaccine was developed by Symvivo Corporation. As of June, 2020, the company is pursuing a Phase 1, Randomized, Observer-Blind, Placebo-Controlled Trial (NCT04334980) to...
Investigational
Matched Description: … BacTRL-Spike is composed of a bacterial medium with colony-forming-units of live Bifidobacterium longum ... As of June, 2020, the company is pursuing a Phase 1, Randomized, Observer-Blind, Placebo-Controlled …
VGV-1
VGV-1 is a potential salvage therapy for treatment of HIV infected people who have failed anti-retroviral therapy.
Investigational
Matched Description: … VGV-1 is a potential salvage therapy for treatment of HIV infected people who have failed anti-retroviral …
Niguldipine
Niguldipine is a calcium channel blocker drug (CCB) with a1-adrenergic antagonist properties.
Experimental
Matched Description: … Niguldipine is a calcium channel blocker drug (CCB) with a1-adrenergic antagonist properties. …
Gestonorone
Gestonorone is often mistaken for gestonorone capproate which has a different chemical structure.
Experimental
Matched Description: … Gestonorone is often mistaken for gestonorone capproate which has a different chemical structure. …
TNG908
TNG908 is a small molecule inhibitor of protein arginine methyl transferase 5 (PRMT5).
Investigational
Matched Description: … TNG908 is a small molecule inhibitor of protein arginine methyl transferase 5 (PRMT5). …
TTAX01
TTAX01 is a cryopreserved human umbilical cord product being developed by TissueTech.
Investigational
Matched Description: … TTAX01 is a cryopreserved human umbilical cord product being developed by TissueTech.[L47246] …
INBRX-101
INBRX-101 is a recombinant human alpha-1 antitrypsin (AAT)-Fc fusion protein.
Investigational
Matched Description: … INBRX-101 is a recombinant human alpha-1 antitrypsin (AAT)-Fc fusion protein. …
VTP-201227
VTP-201227 has a novel mechanism of action and is being developed as a topical agent for the treatment of psoriasis with potential extensions into other dermatological indications. It is being developed by Vitae Pharmaceuticals.
Investigational
Matched Description: … VTP-201227 has a novel mechanism of action and is being developed as a topical agent for the treatment …
Displaying drugs 10776 - 10800 of 11800 in total