Displaying drugs 10826 - 10850 of 12647 in total
Elafin
Elafin is a human protein that is produced naturally in the skin, lung and breast, protecting the respective tissue from destruction by the immune system. Elafin’s ability to block the activity of destructive enzymes that are involved in inflammatory reactions makes it a highly promising active compound for the treatment...
Investigational
Matched Description: … makes it a highly promising active compound for the treatment of inflammatory lung diseases or severe ... Elafin’s ability to block the activity of destructive enzymes that are involved in inflammatory reactions ... The excellent tolerability of Elafin in human subjects was demonstrated in a Phase I clinical single …
Tipifarnib
Tipifarnib (R-115777) is a substance that is being studied in the treatment of acute myeloid leukemia (AML) and other types of cancer. It belongs to the family of drugs called farnesyltransferase inhibitors. It is also called Zarnestra. In June 2005, the FDA issued a Not Approvable Letter for Zarnestra.
Investigational
Matched Description: … (AML) and other types of cancer. ... It belongs to the family of drugs called farnesyltransferase inhibitors. ... Tipifarnib (R-115777) is a substance that is being studied in the treatment of acute myeloid leukemia …
Norclozapine
ACP-104, or N-desmethylclozapine, is the major metabolite of clozapine, and is being developed by ACADIA as a novel, stand-alone therapy for schizophrenia. It combines an atypical antipsychotic efficacy profile with the added potential benefit of enhanced cognition, thereby addressing one of the major challenges in treating schizophrenia today.
Investigational
Matched Description: … , thereby addressing one of the major challenges in treating schizophrenia today. ... ACP-104, or N-desmethylclozapine, is the major metabolite of clozapine, and is being developed by ACADIA ... It combines an atypical antipsychotic efficacy profile with the added potential benefit of enhanced cognition …
Amfecloral
Amfecloral is a stimulant drug of the phenethylamine and amphetamine chemical classes. For a short period of time, it was available under the brand Acutran and indicated as an appetite suppressant, but this product no longer exists. It acts as a prodrug which splits to form amphetamine and chloral hydrate,...
Experimental
Matched Description: … the stimulant effects of the amphetamine metabolite. ... Amfecloral is a stimulant drug of the phenethylamine and amphetamine chemical classes. ... chloral hydrate metabolite is a gabaminergic sedative/hypnotic, and would in theory counteract some of …
Setrusumab
Setrusumab is under investigation in clinical trial NCT01406548 (Safety and Efficacy of Multiple Dosing Regimens of BPS804 in Post Menopausal Women With Low Bone Mineral Density).
Investigational
Matched Description: … Regimens of BPS804 in Post Menopausal Women With Low Bone Mineral Density). ... Setrusumab is under investigation in clinical trial NCT01406548 (Safety and Efficacy of Multiple Dosing …
Vofatamab
Vofatamab is under investigation in clinical trial NCT02401542 (Dose Escalation, Expansion Study of Vofatamab (B-701) in Treatment of Locally Advanced or Metastatic Urothelial Cell Carcinoma).
Investigational
Matched Description: … (B-701) in Treatment of Locally Advanced or Metastatic Urothelial Cell Carcinoma). ... Vofatamab is under investigation in clinical trial NCT02401542 (Dose Escalation, Expansion Study of Vofatamab …
Imalumab
Imalumab is under investigation in clinical trial NCT02540356 (Phase 1/2a Two-arm Dose-escalation Study of BAX69 in Subjects With Malignant Ascites of Ovarian Cancer).
Investigational
Matched Description: … BAX69 in Subjects With Malignant Ascites of Ovarian Cancer). ... Imalumab is under investigation in clinical trial NCT02540356 (Phase 1/2a Two-arm Dose-escalation Study of …
Milciclib Maleate
Milciclib Maleate is under investigation in clinical trial NCT01301391 (Study of Oral PHA-848125AC in Patients With Malignant Thymoma Previously Treated With Multiple Lines of Chemotherapy).
Investigational
Matched Description: … Patients With Malignant Thymoma Previously Treated With Multiple Lines of Chemotherapy). ... Milciclib Maleate is under investigation in clinical trial NCT01301391 (Study of Oral PHA-848125AC in …
Pegcantratinib
Pegcantratinib is under investigation in clinical trial NCT03448081 (Safety, Tolerability and Efficacy of SNA-120 for Treatment of Pruritus and Psoriasis in Subjects Treated With Calcipotriene).
Investigational
Matched Description: … SNA-120 for Treatment of Pruritus and Psoriasis in Subjects Treated With Calcipotriene). ... Pegcantratinib is under investigation in clinical trial NCT03448081 (Safety, Tolerability and Efficacy of …
HSK-3486
HSK-3486 is under investigation in clinical trial NCT04620031 (A Study Evaluating Sedation of Intravenous Administration of HSK3486 Injectable Emulsion in ICU Patients Undergoing Mechanical Ventilation).
Investigational
Matched Description: … Administration of HSK3486 Injectable Emulsion in ICU Patients Undergoing Mechanical Ventilation). ... HSK-3486 is under investigation in clinical trial NCT04620031 (A Study Evaluating Sedation of Intravenous …
Letaplimab
Letaplimab is under investigation in clinical trial NCT04485052 (Efficacy and Safety Evaluation of IBI188 in Combination With Azacitidine in Treatment of Patients With Acute Myeloid Leukemia).
Investigational
Matched Description: … in Combination With Azacitidine in Treatment of Patients With Acute Myeloid Leukemia). ... Letaplimab is under investigation in clinical trial NCT04485052 (Efficacy and Safety Evaluation of IBI188 …
Alfimeprase
Alfimeprase is a recombinant analog of fibrolase. Fibrolase is a zinc-containing metalloproteinase isolated from the venom of the southern copperhead snake (Agkistrodon contortrix contortrix). It is a small protein that contains 203 residues (Randolph et al. 1992). Alfimeprase is being developed by Nuvelo.
Investigational
Matched Description: … Alfimeprase is a recombinant analog of fibrolase. ... Fibrolase is a zinc-containing metalloproteinase isolated from the venom of the southern copperhead snake …
CTx-PDE6b
CTx-PDE6b is an adeno-associated virus (AAV) based gene therapy designed to deliver a full-length non-mutated copy of the functional human PDE6b gene. Being commercialied by Coave Therapeutics, it is being investigated for the treatment of retinitis pigmentosa due to PDE6b gene mutations.
Investigational
Matched Description: … adeno-associated virus (AAV) based gene therapy designed to deliver a full-length non-mutated copy of ... Being commercialied by Coave Therapeutics, it is being investigated for the treatment of retinitis pigmentosa …
Diethyltryptamine
Diethyltryptamine (DET) is an orally active hallucinogenic agent and a substituted form of tryptamine.
Experimental
Illicit
Matched Description: … Diethyltryptamine (DET) is an orally active hallucinogenic agent and a substituted form of tryptamine …
NCX 950
NCX 950, beta2-adrenoceptor agonists is widely used in the treatment of pulmonary diseases.
Investigational
Matched Description: … NCX 950, beta2-adrenoceptor agonists is widely used in the treatment of pulmonary diseases. …
Apabetalone
Apabetalone has been investigated for the treatment of Diabetes, Atherosclerosis, and Coronary Artery Disease.
Investigational
Matched Description: … Apabetalone has been investigated for the treatment of Diabetes, Atherosclerosis, and Coronary Artery …
Luseogliflozin
Luseogliflozin has been used in trials studying the treatment of Diabetes Melltius, Type 2.
Investigational
Matched Description: … Luseogliflozin has been used in trials studying the treatment of Diabetes Melltius, Type 2. …
Isunakinra
Isunakinra has been investigated for the treatment of Dry Eye and Allergic Conjunctivitis (AC).
Investigational
Matched Description: … Isunakinra has been investigated for the treatment of Dry Eye and Allergic Conjunctivitis (AC). …
Fenamole
Fenamole has been investigated for the supportive care of Side Effects and Dental Plaque.
Investigational
Matched Description: … Fenamole has been investigated for the supportive care of Side Effects and Dental Plaque. …
Carlumab
Carlumab has been used in trials studying the treatment of Cancer and Prostate Cancer.
Investigational
Withdrawn
Matched Description: … Carlumab has been used in trials studying the treatment of Cancer and Prostate Cancer. …
Crotedumab
Crotedumab has been used in trials studying the treatment of Diabetes Mellitus, Type 2.
Investigational
Matched Description: … Crotedumab has been used in trials studying the treatment of Diabetes Mellitus, Type 2. …
Miravirsen
Miravirsen has been investigated for the treatment of Hepatitis C and Hepatitis C, Chronic.
Investigational
Matched Description: … Miravirsen has been investigated for the treatment of Hepatitis C and Hepatitis C, Chronic. …
Corticorelin acetate
Corticorelin acetate has been investigated for the treatment of Brain Edema and Brain Tumor.
Investigational
Matched Description: … Corticorelin acetate has been investigated for the treatment of Brain Edema and Brain Tumor. …
Nepicastat
Nepicastat has been investigated for the treatment of Cocaine Dependence and Posttraumatic Stress Disorder.
Investigational
Matched Description: … Nepicastat has been investigated for the treatment of Cocaine Dependence and Posttraumatic Stress Disorder …
LI-301
LI 301 is an orally bio-available compound delivered in a fast melt mechanism with taste masking enabling it to be taken anytime without water. It has a novel mode of action combining both the light effect of a Selective Serotonin Reuptake Inhibitor ("SSRI")(most likely antagonistic at 5HT1a receptors) and antagonism...
Investigational
Matched Description: … It has a novel mode of action combining both the light effect of a Selective Serotonin Reuptake Inhibitor ... This results in a slight dulling of sensation that can be used to treat premature ejaculation without …
Displaying drugs 10826 - 10850 of 12647 in total