Displaying drugs 10901 - 10925 of 12647 in total
IDD-1
Lipids promote the fusion of liposomes to cells. Eladem (IDD-1) is a therapeutic vaccine consisting of dendritophages that are loaded in vitro with tumor antigens and then reinjected into the subject. As with other monoclonal antibodies, this process stimulates an immune response to a particular disease-related antigen.
Investigational
Matched Description: … Lipids promote the fusion of liposomes to cells. ... Eladem (IDD-1) is a therapeutic vaccine consisting of dendritophages that are loaded in vitro with tumor …
OSI-7904L
OSI-7904L is a liposome encapsulated thymidylate synthase inhibitor, which is indicated for use in advanced gastric and/or gastroesophageal adenocarcinoma (A-G/GEJA). Current treatments also inhibit thymidylate synthase but the innovative lipid coating of OSI-7904L allows for more enduring results with administration of the TS inhibitor.
Investigational
Matched Description: … for more enduring results with administration of the TS inhibitor. ... Current treatments also inhibit thymidylate synthase but the innovative lipid coating of OSI-7904L allows …
TB-402
TB-402 is a human antibody binding to Factor VIII, which plays a crucial role in the coagulation of the blood. It is expected to be developed as a potential treatment to prevent blood clot formation in connection with certain types of heart arrhythmia, such as atrial fibrillation.
Investigational
Matched Description: … TB-402 is a human antibody binding to Factor VIII, which plays a crucial role in the coagulation of the ... developed as a potential treatment to prevent blood clot formation in connection with certain types of …
Myrcludex B
Myrcludex B is under investigation in clinical trial NCT03546621 (A Multicenter, Open-label, Randomized Clinical Study to Assess Efficacy and Safety of 3 Doses of Myrcludex B for 24 Weeks in Combination With Tenofovir Compared to Tenofovir Alone to Suppress HBV Replication in Patients With Chronic Hepatitis D).
Investigational
Matched Description: … trial NCT03546621 (A Multicenter, Open-label, Randomized Clinical Study to Assess Efficacy and Safety of ... 3 Doses of Myrcludex B for 24 Weeks in Combination With Tenofovir Compared to Tenofovir Alone to Suppress …
(1R, 2S)-cis 1,2 dihydroxy-1,2-dihydronaphthalene
(1R, 2S)-cis 1,2 dihydroxy-1,2-dihydronaphthalene is a solid. This compound belongs to the naphthalenes. These are compounds containing a naphthalene moiety, which consists of two fused benzene rings. Known drug targets of (1R, 2S)-cis 1,2 dihydroxy-1,2-dihydronaphthalene include naphthalene 1,2-dioxygenase subunit beta and naphthalene 1,2-dioxygenase subunit alpha.
Experimental
Matched Description: … These are compounds containing a naphthalene moiety, which consists of two fused benzene rings. ... Known drug targets of (1R, 2S)-cis 1,2 dihydroxy-1,2-dihydronaphthalene include naphthalene 1,2-dioxygenase …
SPL84-23-1
SPL84-23-1 is a sodium salt of 19-bp single-stranded RNA uniformly modified 2'-O-(2-methoxyethyl) phosphorothioate Antisense Oligonucleotide (ASO) consisting of 19 nucleotide residues with the sequence 5'-5MeC-5MeU-G-5MeC-A-A-5MeC-A-G-A-5MeU-G-G-A-A-G-A-5MeC-5MeU-3'
Investigational
Matched Description: … Antisense Oligonucleotide (ASO) consisting of 19 nucleotide residues with the sequence 5'-5MeC-5MeU-G ... SPL84-23-1 is a sodium salt of 19-bp single-stranded RNA uniformly modified 2'-O-(2-methoxyethyl) phosphorothioate …
Etryptamine
In the 1960's, alpha-ethyltryptamine (αET), a non hydrazine reversible monoamine oxidase inhibitor, was developed in the United States by the Upjohn chemical company for use as an antidepressant. αET was an FDA approved antidepressant under the name Monase. However, in 1962, after the discovery of an unacceptable incidence of agranulocytosis,...
Illicit
Investigational
Withdrawn
Matched Description: … However, in 1962, after the discovery of an unacceptable incidence of agranulocytosis, the development ... In 1993, the US Drug Enforcement Administration added αET to Schedule I of its Schedules of Controlled ... of Monase was halted and the drug was withdrawn from potential market use. …
ATL-104
ATL-104 is a potent mitogen for epithelial cells of the gastrointestinal tract. In animal models, ATL-104 aids regeneration of the gastrointestinal tract after treatment with chemotherapeutic agents.
Investigational
Matched Description: … ATL-104 is a potent mitogen for epithelial cells of the gastrointestinal tract. ... In animal models, ATL-104 aids regeneration of the gastrointestinal tract after treatment with chemotherapeutic …
Indusatumab vedotin
Indusatumab vedotin has been used in trials studying the treatment of Pancreatic Adenocarcinoma, Adenocarcinoma of the Stomach, Recurrent Gastric Adenocarcinoma, Metastatic Gastric Adenocarcinoma, and Advanced Gastrointestinal Carcinoma, among others.
Investigational
Matched Description: … Indusatumab vedotin has been used in trials studying the treatment of Pancreatic Adenocarcinoma, Adenocarcinoma ... of the Stomach, Recurrent Gastric Adenocarcinoma, Metastatic Gastric Adenocarcinoma, and Advanced Gastrointestinal …
Nemiralisib
Nemiralisib is under investigation in clinical trial NCT03345407 (Dose Finding Study of Nemiralisib (GSK2269557) in Subjects With an Acute Moderate or Severe Exacerbation of Chronic Obstructive Pulmonary Disease (COPD)).
Investigational
Matched Description: … Nemiralisib is under investigation in clinical trial NCT03345407 (Dose Finding Study of Nemiralisib ( ... GSK2269557) in Subjects With an Acute Moderate or Severe Exacerbation of Chronic Obstructive Pulmonary …
Depulfavirine
Depulfavirine is under investigation in clinical trial NCT05204394 (Study to Evaluate Efficacy and Safety of Switching to VM-1500A-LAI + 2nrtis From the 1st Line Standard of Care Therapy).
Investigational
Matched Description: … Switching to VM-1500A-LAI + 2nrtis From the 1st Line Standard of Care Therapy). ... Depulfavirine is under investigation in clinical trial NCT05204394 (Study to Evaluate Efficacy and Safety of …
alpha-D-quinovopyranose
The pyranose form of D-quinovose with an α-configuration at the anomeric position .
Experimental
Matched Description: … The pyranose form of D-quinovose with an α-configuration at the anomeric position . …
Atl146e
ATL146e is an anti-inflammatory compounds which is an agonist of A2A adenosine receptors.
Investigational
Matched Description: … ATL146e is an anti-inflammatory compounds which is an agonist of A2A adenosine receptors. …
FAV-201
FAV-201 is a patient-specific immunotherapy for the treatment of T-cell lymphoma.
Investigational
Matched Description: … FAV-201 is a patient-specific immunotherapy for the treatment of T-cell lymphoma. …
Bryostatin 1
Bryostatin 1 has been investigated for the treatment of HIV Infection and Alzheimer's Disease.
Investigational
Matched Description: … Bryostatin 1 has been investigated for the treatment of HIV Infection and Alzheimer's Disease. …
Interleukin-7
Interleukin 7 has been used in trials studying the treatment of Metastatic Breast Cancer.
Investigational
Matched Description: … Interleukin 7 has been used in trials studying the treatment of Metastatic Breast Cancer. …
Esreboxetine
Esreboxetine has been used in trials studying the treatment and basic science of Fibromyalgia.
Investigational
Matched Description: … Esreboxetine has been used in trials studying the treatment and basic science of Fibromyalgia. …
Muscimol
Muscimol has been used in trials studying the treatment of Epilepsy and Parkinson's Disease.
Investigational
Matched Description: … Muscimol has been used in trials studying the treatment of Epilepsy and Parkinson's Disease. …
AKN-028
AKN-028 has been used in trials studying the treatment of Acute Myeloid Leukemia.
Investigational
Matched Description: … AKN-028 has been used in trials studying the treatment of Acute Myeloid Leukemia. …
Methylinositol
Methylinositol has been used in trials studying the treatment of Dementia and Alzheimer's Disease.
Investigational
Matched Description: … Methylinositol has been used in trials studying the treatment of Dementia and Alzheimer's Disease. …
Nattokinase
Nattokinase is under investigation in clinical trial NCT00749801 (Efficacy and Safety of Geneferm Nattokinase).
Investigational
Matched Description: … Nattokinase is under investigation in clinical trial NCT00749801 (Efficacy and Safety of Geneferm Nattokinase …
Idursulfase beta
Idursulfase beta is under investigation in clinical trial NCT01645189 (Safety and Efficacy of Hunterase).
Investigational
Matched Description: … Idursulfase beta is under investigation in clinical trial NCT01645189 (Safety and Efficacy of Hunterase …
CDX-6210
CDX-6210 is a modified version of a leucine decarboxylase enzyme from Planctomycetaceae bacterium.
Investigational
Matched Description: … CDX-6210 is a modified version of a leucine decarboxylase enzyme from _Planctomycetaceae bacterium_. …
PT886
PT886 is a bispecific antibody against Claudin 18.2 and cluster of differentiation 47 (CD47)
Investigational
Matched Description: … PT886 is a bispecific antibody against Claudin 18.2 and cluster of differentiation 47 (CD47) …
XL844
XL844 is investigated for the use and treatment solid tumors. XL844 is a solid. XL844 is a potent inhibitor of the checkpoint kinases CHK1 and CHK2, which induce cell cycle arrest in response to a variety of DNA damaging agents. Known drug targets of XL844 including serine/threonine-protein kinase Chk1 and...
Investigational
Matched Description: … response to a variety of DNA damaging agents. ... XL844 is a potent inhibitor of the checkpoint kinases CHK1 and CHK2, which induce cell cycle arrest in ... Known drug targets of XL844 including serine/threonine-protein kinase Chk1 and serine/threonine-protein …
Displaying drugs 10901 - 10925 of 12647 in total