Displaying drugs 10926 - 10950 of 11746 in total
Tropifexor
Tropifexor is under investigation in clinical trial NCT02516605 (A Multi-part, Double Blind Study to Assess Safety, Tolerability and Efficacy of Tropifexor (LJN452) in PBC Patients).
Investigational
Matched Description: … Tropifexor is under investigation in clinical trial NCT02516605 (A Multi-part, Double Blind Study to …
TORL-2-307
TORL-2307 is a humanized immunoglobulin G1 (IgG1) monoclonal antibody (mAb) directed against claudin 18.2 (CLDN18.2) being investigated for the treatment of gastric and pancreatic cancer.
Investigational
Matched Description: … TORL-2307 is a humanized immunoglobulin G1 (IgG1) monoclonal antibody (mAb) directed against claudin …
Naporafenib
Naporafenib is under investigation in clinical trial NCT06346067 (A Study to Assess Naporafenib (ERAS-254) Administered With Trametinib in Patients With Nras-mutant Melanoma (SEACRAFT-2)).
Investigational
Matched Description: … Naporafenib is under investigation in clinical trial NCT06346067 (A Study to Assess Naporafenib (ERAS …
Tobemstomig
Tobemstomig is under investigation in clinical trial NCT05908786 (A Study Evaluating the Efficacy and Safety of Neoadjuvant Immunotherapy Combinations in Patients With Surgically Resectable Hepatocellular Carcinoma).
Investigational
Matched Description: … Tobemstomig is under investigation in clinical trial NCT05908786 (A Study Evaluating the Efficacy and …
N2-[(benzyloxy)carbonyl]-n1-[(3S)-1-cyanopyrrolidin-3-yl]-l-leucinamide
N2-[(benzyloxy)carbonyl]-n1-[(3S)-1-cyanopyrrolidin-3-yl]-l-leucinamide is a solid. This compound belongs to the n-acyl-alpha amino acids and derivatives. These are compounds containing an alpha amino acid (or a derivative thereof) which bears an acyl group at its terminal nitrogen atom. It is known to target cathepsin K.
Experimental
Matched Description: … N2-[(benzyloxy)carbonyl]-n1-[(3S)-1-cyanopyrrolidin-3-yl]-l-leucinamide is a solid. ... These are compounds containing an alpha amino acid (or a derivative thereof) which bears an acyl group …
Gevokizumab
Gevokizumab has been used in trials studying the treatment of Acne Vulgaris, Osteoarthritis, Behcet's Uveitis, Pyoderma Gangrenosum, and Behcet's Disease Uveitis, among others. Gevokizumab acts as a modulator of cytokine imbalance in IL-1 mediated disease states. It has a very high binding affinity of 300fM and blocks the activation of...
Investigational
Matched Description: … Gevokizumab acts as a modulator of cytokine imbalance in IL-1 mediated disease states. ... It has a very high binding affinity of 300fM and blocks the activation of IL-1 receptors. …
GMX1777
GMX1777 is a water-soluble prodrug of the cyanoguanidine compound GMX1778 with potential antineoplastic activity. In vivo, apoptosis inducer GMX1777 is rapidly converted into GMX1778 through hydrolytic cleavage of a carbonate ester bond. Although the exact mechanism of action has yet to be fully elucidated, GMX1778 appears to antagonize nuclear factor-kappa...
Investigational
Matched Description: … GMX1777 is a water-soluble prodrug of the cyanoguanidine compound GMX1778 with potential antineoplastic ... In vivo, apoptosis inducer GMX1777 is rapidly converted into GMX1778 through hydrolytic cleavage of a …
PAC-113
PAC-113 an anti-fungal, for the treatment of oral candidiasis infections. It is a 12 amino-acid antimicrobial peptide derived from a naturally occurring histatin protein found in saliva. In vitro studies demonstrate that it has potent anti-fungal activity against the Candida albicans, including drug-resistant HIV patient isolates. PAC-113 is targeting oral...
Investigational
Matched Description: … It is a 12 amino-acid antimicrobial peptide derived from a naturally occurring histatin protein found …
Orgotein
Superoxide is a natural byproduct of oxygen metabolism which, if left unchecked, leads to cell damage. Superoxide dismutase (SOD) is an enzyme that alternately catalyzes the dismutation of the superoxide radical into either the less damaging hydrogen peroxide or molecular oxygen. Hydrogen peroxide can be degraded by catalase. The antioxidant...
Investigational
Vet approved
Matched Description: … A notable exception is Lactobacillus plantarum. ... Superoxide is a natural byproduct of oxygen metabolism which, if left unchecked, leads to cell damage …
Topsalysin
Topsalysin is being developed for the treatment of localized prostate cancer and also benign prostatic hyperplasia. Topsalysin is delivered locally to the prostate under ultrasound guidance.
Investigational
Tifuvirtide
Tifuvirtide is the first members of a new class of anti-HIV drugs which is also called fusion inhibitors. It has received fast-track designation from the FDA and is in Phase I/II clinical testing.
Investigational
Matched Description: … Tifuvirtide is the first members of a new class of anti-HIV drugs which is also called fusion inhibitors …
REV131
rEV131 is in development for allergic rhinitis, asthma and several inflammatory eye diseases. It is a topically delivered small protein that acts as an anti-inflammatory agent.
Investigational
Matched Description: … It is a topically delivered small protein that acts as an anti-inflammatory agent. …
LGD2941
LGD2941 is a non-steroidal, selective androgen receptor modulator (SARM) developed jointly by Ligand and TAP.
Investigational
Matched Description: … LGD2941 is a non-steroidal, selective androgen receptor modulator (SARM) developed jointly by Ligand …
Repinotan
Repinotan is a high-affinity, selective, full agonist of the 5HT1A-receptor subtype with neuroprotective properties.
Investigational
Matched Description: … Repinotan is a high-affinity, selective, full agonist of the 5HT1A-receptor subtype with neuroprotective …
Flumequine
Flumequine is a synthetic chemotherapeutic antibiotic of the fluoroquinolone drug class used to treat bacterial infections.
Withdrawn
Matched Description: … Flumequine is a synthetic chemotherapeutic antibiotic of the fluoroquinolone drug class used to treat …
Clorindione
Clorindione is a vitamin K antagonist, which may be useful to decrease prothrombin levels in humans.
Experimental
Matched Description: … Clorindione is a vitamin K antagonist, which may be useful to decrease prothrombin levels in humans. …
GsMtx-4
GsMtx-4 is a peptide found in tarantula venom that inhibits mechanosensitive ion channel (MSC) activity.
Investigational
Matched Description: … GsMtx-4 is a peptide found in tarantula venom that inhibits mechanosensitive ion channel (MSC) activity …
GIVI-MPC
GIVI-MPC is a therapy that uses human-induced pluripotent stem cell-derived myogenic progenitor cells.
Investigational
Matched Description: … GIVI-MPC is a therapy that uses human-induced pluripotent stem cell-derived myogenic progenitor cells …
P-42 peptide
P-42 peptide is a synthetic 23 amino acid peptide AASSGVSTPGSAGHDIITEQPRS derived from the Huntingtin protein
Investigational
Matched Description: … P-42 peptide is a synthetic 23 amino acid peptide AASSGVSTPGSAGHDIITEQPRS derived from the Huntingtin …
Cytidine-5'-Diphosphate
Cytidine 5'-(trihydrogen diphosphate). A cytosine nucleotide containing two phosphate groups esterified to the sugar moiety. Synonyms: CRPP; cytidine pyrophosphate. [PubChem]
Experimental
Matched Description: … A cytosine nucleotide containing two phosphate groups esterified to the sugar moiety. …
REP8839
REP8839 is a novel methionyl-tRNA synthetase (MetS) inhibitor being developed by Replidyne (GlaxoSmithKline licensed REP8839 to Replidyne in June of 2003).
Investigational
Matched Description: … REP8839 is a novel methionyl-tRNA synthetase (MetS) inhibitor being developed by Replidyne (GlaxoSmithKline …
MAHDL01
MAHDL01 is a pharmaceutical combination of whole plants, which is used to increase the HDL/LDL ratio that improves overall cardiovascular health.
Investigational
Matched Description: … MAHDL01 is a pharmaceutical combination of whole plants, which is used to increase the HDL/LDL ratio …
Phellinus linteus mycelium
Phellinus linteus mycelium is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Description: … Phellinus linteus mycelium is a plant/plant extract used in some OTC (over-the-counter) products. …
Reynoutria multiflora root
Reynoutria multiflora root is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Description: … Reynoutria multiflora root is a plant/plant extract used in some OTC (over-the-counter) products. …
Indigofera tinctoria leaf
Indigofera tinctoria leaf is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Description: … Indigofera tinctoria leaf is a plant/plant extract used in some OTC (over-the-counter) products. …
Displaying drugs 10926 - 10950 of 11746 in total