Displaying drugs 1076 - 1100 of 3382 in total
PF-5212372
PF-5212372 is under investigation in clinical trial NCT02795832 (A Study to Determine the Safety & Efficacy of ZPL-5212372 in Healthy Subjects and in Subjects With Atopic Dermatitis).
Investigational
Matched Synonyms: … Benzenepropanoic acid, 4-((2-(5-chloro-1-(diphenylmethyl)-2-(2-((((2-(trifluoromethyl)phenyl)methyl)sulfonyl ... )amino)ethyl)-1h-indol-3-yl)ethyl)sulfonyl)- …
Matched Description: … clinical trial NCT02795832 (A Study to Determine the Safety & Efficacy of ZPL-5212372 in Healthy Subjects and …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids …
Matched Description: … clinical trial NCT02795832 (A Study to Determine the Safety & Efficacy of ZPL-5212372 in Healthy Subjects and …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids …
Chlorambucil
A nitrogen mustard alkylating agent used as antineoplastic agent for the treatment of various malignant and nonmalignant diseases. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
Approved
Matched Synonyms: … Phenylbutyric acid nitrogen mustard ... 4-(p-bis(beta-chloroethyl)aminophenyl)butyric acid ... 4-(p-bis(β-chloroethyl)aminophenyl)butyric acid …
Matched Iupac: … 4-{4-[bis(2-chloroethyl)amino]phenyl}butanoic acid …
Matched Description: … nitrogen mustard alkylating agent used as antineoplastic agent for the treatment of various malignant and …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Iupac: … 4-{4-[bis(2-chloroethyl)amino]phenyl}butanoic acid …
Matched Description: … nitrogen mustard alkylating agent used as antineoplastic agent for the treatment of various malignant and …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Ditiocarb zinc
Ditiocarb zinc, also known as Diethyldithiocarbamic acid zinc salt, is a known chelator for copper and zinc. It also a dermatological sensitizer and allergen. Sensitivity to ditiocarb zinc may be identified with a clinical patch test.
Approved
Matched Synonyms: … Diethyldithiocarbamic acid zinc salt ... Ethyl Ziram ... Ethyl cymate …
Matched Description: … Ditiocarb zinc, also known as Diethyldithiocarbamic acid zinc salt, is a known chelator for copper and ... It also a dermatological sensitizer and allergen. …
Matched Categories: … Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use ... Acids, Acyclic ... Carboxylic Acids …
Matched Description: … Ditiocarb zinc, also known as Diethyldithiocarbamic acid zinc salt, is a known chelator for copper and ... It also a dermatological sensitizer and allergen. …
Matched Categories: … Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use ... Acids, Acyclic ... Carboxylic Acids …
Lofexidine
Lofexidine is a non-opioid centrally acting alpha2-adrenergic receptor agonist that was first approved for the treatment of opioid withdrawal in the United Kingdom in 1992. It was first studied for use as an antihypertensive in 1980, but its researched was stopped as it was found less effective for the treatment...
Approved
Investigational
Matched Synonyms: … 2-(alpha-(2,6-Dichlorophenoxy)ethyl)2-imidazoline …
Matched Iupac: … 2-[1-(2,6-dichlorophenoxy)ethyl]-4,5-dihydro-1H-imidazole …
Matched Description: … [T209] Lofexidine was developed by US Woldmeds LLC and it was approved by the FDA on May 16, 2018. ... Lofexidine was then repurposed for the treatment of opioid withdrawal, as it was seen to be more economical and ... Lofexidine is a non-opioid centrally acting alpha2-adrenergic receptor agonist that was first approved …
Matched Categories: … Adrenergic alpha-Agonists ... Adrenergic alpha-2 Receptor Agonists ... Central alpha-2 Adrenergic Agonist …
Matched Iupac: … 2-[1-(2,6-dichlorophenoxy)ethyl]-4,5-dihydro-1H-imidazole …
Matched Description: … [T209] Lofexidine was developed by US Woldmeds LLC and it was approved by the FDA on May 16, 2018. ... Lofexidine was then repurposed for the treatment of opioid withdrawal, as it was seen to be more economical and ... Lofexidine is a non-opioid centrally acting alpha2-adrenergic receptor agonist that was first approved …
Matched Categories: … Adrenergic alpha-Agonists ... Adrenergic alpha-2 Receptor Agonists ... Central alpha-2 Adrenergic Agonist …
A-674563
Experimental
Matched Synonyms: … (alphaS)-alpha-(((5-(3-Methyl-1H-indazol-5-yl)-3-pyridinyl)oxy)methyl)benzeneethanamine …
Quilseconazole
Investigational
Matched Synonyms: … -difluoro-.alpha.-(1h-tetrazol-1-ylmethyl)-5-(4-(trifluoromethoxy)phenyl)-, (.alpha.r)- ... 2-pyridineethanol, .alpha.-(2,4-difluorophenyl)-.beta.,.beta. …
SR-9009
SR-9009 is a REV-ERB agonist. SR-9011 has been demonstrated that it is specifically lethal to cancer cells and oncogene-induced senescent cells, including melanocytic naevi, and has no effect on the viability of normal cells or tissues .
Experimental
Matched Synonyms: … ethyl ester ... 1-Pyrrolidinecarboxylic acid, 3-((((4-chlorophenyl)methyl)((5-nitro-2-thienyl)methyl)amino)methyl)-, …
Matched Iupac: … ethyl 3-({[(4-chlorophenyl)methyl][(5-nitrothiophen-2-yl)methyl]amino}methyl)pyrrolidine-1-carboxylate …
Matched Description: … SR-9011 has been demonstrated that it is specifically lethal to cancer cells and oncogene-induced senescent ... cells, including melanocytic naevi, and has no effect on the viability of normal cells or tissues [A32628 …
Matched Iupac: … ethyl 3-({[(4-chlorophenyl)methyl][(5-nitrothiophen-2-yl)methyl]amino}methyl)pyrrolidine-1-carboxylate …
Matched Description: … SR-9011 has been demonstrated that it is specifically lethal to cancer cells and oncogene-induced senescent ... cells, including melanocytic naevi, and has no effect on the viability of normal cells or tissues [A32628 …
m-Hydroxyhippuric acid
Experimental
Matched Synonyms: … 3-hydroxyhippuric acid ... 2-[(3-hydroxyphenyl)formamido]acetic acid …
Matched Name: … m-Hydroxyhippuric acid …
Matched Iupac: … 2-[(3-hydroxyphenyl)formamido]acetic acid …
Matched Categories: … Benzamides and benzamide derivatives ... Acids, Carbocyclic ... Keto Acids ... Carboxylic Acids …
Matched Name: … m-Hydroxyhippuric acid …
Matched Iupac: … 2-[(3-hydroxyphenyl)formamido]acetic acid …
Matched Categories: … Benzamides and benzamide derivatives ... Acids, Carbocyclic ... Keto Acids ... Carboxylic Acids …
L-threonic acid
Experimental
Matched Synonyms: … L-threonic acid ... (2R,3S)-2,3,4-trihydroxy-butanoic acid …
Matched Name: … L-threonic acid …
Matched Iupac: … (2R,3S)-2,3,4-trihydroxybutanoic acid …
Matched Categories: … Fatty Acids ... Acids, Acyclic ... Carboxylic Acids ... Fatty Acids, Volatile …
Matched Name: … L-threonic acid …
Matched Iupac: … (2R,3S)-2,3,4-trihydroxybutanoic acid …
Matched Categories: … Fatty Acids ... Acids, Acyclic ... Carboxylic Acids ... Fatty Acids, Volatile …
Mepenzolate
Mepenzolate is a post-ganglionic parasympathetic inhibitor. It decreases gastric acid and pepsin secretion and suppresses spontaneous contractions of the colon. Mepenzolate diminishes gastric acid and pepsin secretion. Mepenzolate also suppresses spontaneous contractions of the colon. Pharmacologically, it is a post-ganglionic parasympathetic inhibitor. It has not been shown to be effective...
Approved
Matched Synonyms: … Mepenzolic acid …
Matched Description: … Mepenzolate diminishes gastric acid and pepsin secretion. ... It decreases gastric acid and pepsin secretion and suppresses spontaneous contractions of the colon. …
Matched Categories: … Alimentary Tract and Metabolism ... Acids, Carbocyclic ... Carboxylic Acids ... Hydroxy Acids ... Diphenylacetic Acids …
Matched Description: … Mepenzolate diminishes gastric acid and pepsin secretion. ... It decreases gastric acid and pepsin secretion and suppresses spontaneous contractions of the colon. …
Matched Categories: … Alimentary Tract and Metabolism ... Acids, Carbocyclic ... Carboxylic Acids ... Hydroxy Acids ... Diphenylacetic Acids …
Tamibarotene
Tamibarotene is a novel synthetic retinoid for acute promyelocytic leukaemia (APL). Tamibarotene is currently approved in Japan for treatment of recurrent APL, and is undergoing clinical trials in the United States.
Investigational
Matched Synonyms: … retinobenzoic acid …
Matched Iupac: … 4-[(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)carbamoyl]benzoic acid …
Matched Description: … Tamibarotene is currently approved in Japan for treatment of recurrent APL, and is undergoing clinical …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids …
Matched Iupac: … 4-[(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)carbamoyl]benzoic acid …
Matched Description: … Tamibarotene is currently approved in Japan for treatment of recurrent APL, and is undergoing clinical …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids …
Diaminopropanol tetraacetic acid
Diaminohydroxypropanetetraacetic acid has been investigated for the treatment of Vascular Disease, Coronary Disease, Myocardial Ischemia, Coronary Restenosis, and Coronary Artery Disease, among others.
Approved
Investigational
Matched Synonyms: … Diaminohydroxypropanetetraacetic acid …
Matched Name: … Diaminopropanol tetraacetic acid …
Matched Iupac: … 2-({3-[bis(carboxymethyl)amino]-2-hydroxypropyl}(carboxymethyl)amino)acetic acid …
Matched Description: … Disease, Myocardial Ischemia, Coronary Restenosis, and Coronary Artery Disease, among others. ... Diaminohydroxypropanetetraacetic acid has been investigated for the treatment of Vascular Disease, Coronary …
Matched Name: … Diaminopropanol tetraacetic acid …
Matched Iupac: … 2-({3-[bis(carboxymethyl)amino]-2-hydroxypropyl}(carboxymethyl)amino)acetic acid …
Matched Description: … Disease, Myocardial Ischemia, Coronary Restenosis, and Coronary Artery Disease, among others. ... Diaminohydroxypropanetetraacetic acid has been investigated for the treatment of Vascular Disease, Coronary …
Genipin
Genipin is under investigation in clinical trial NCT05755750 (Intratendinous Genipin Injection in Horses With Tendon Injuries).
Investigational
Matched Synonyms: … , (1r-(1.alpha.,4a.alpha.,7a.alpha ... Cyclopenta(c)pyran-4-carboxylic acid, 1,4a.alpha.,5,7a.alpha. ... Cyclopenta(c)pyran-4-carboxylic acid, 1,4a,5,7a-tetrahydro-1-hydroxy-7-(hydroxymethyl)-, methyl ester …
Matched Categories: … Cholagogues and Choleretics …
Matched Categories: … Cholagogues and Choleretics …
Arginine glutamate
Investigational
Matched Synonyms: … 2-aminoglutaric acid ... 2-amino-5-guanidino-pentanoic acid ... 2-amino-5-(diaminomethylideneamino)pentanoic acid …
Matched Iupac: … (2S)-2-amino-5-carbamimidamidopentanoic acid; (2S)-2-aminopentanedioic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Alimentary Tract and Metabolism ... Bile and Liver Therapy …
Matched Iupac: … (2S)-2-amino-5-carbamimidamidopentanoic acid; (2S)-2-aminopentanedioic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Alimentary Tract and Metabolism ... Bile and Liver Therapy …
3-Phosphono-D-alanine
Experimental
Matched Synonyms: … (S)-2-Amino-3-phosphonopropanoic acid ... D-2-Amino-3-phosphonopropionic acid …
Matched Iupac: … (2S)-2-amino-3-phosphonopropanoic acid …
Matched Iupac: … (2S)-2-amino-3-phosphonopropanoic acid …
NDI-5001
Investigational
Matched Synonyms: … 1,1'-(1,12-dodecanediyl)bis(cyclopropanecarboxylic acid) ... Cyclopropanecarboxylic acid, 1,1'-(1,12-dodecanediyl)bis- ... 1-(12-(1 carboxycyclopropyl)dodecyl)cyclopropane-1-carboxylic acid …
Acetylcysteine
Acetylcysteine is an antioxidant and glutathione inducer indicated for mucolytic therapy and the treatment of acetaminophen overdose.[L31378,L31383,L31388,L31478] Acetylcysteine has also been studied for a wide variety of off-label indications with mixed results.[A228158,A228163,A228168]
Acetylcysteine was granted FDA approval on 14 September 1963.
Approved
Investigational
Matched Synonyms: … Mercapturic acid ... (R)-mercapturic acid ... (2R)-2-acetylamino-3-sulfanylpropanoic acid …
Matched Iupac: … (2R)-2-acetamido-3-sulfanylpropanoic acid …
Matched Description: … Acetylcysteine is an antioxidant and glutathione inducer indicated for mucolytic therapy and the treatment ... [A228158,A228163,A228168] Acetylcysteine was granted FDA approval on 14 September 1963.[L31488] …
Matched Mixtures name: … Levomefolate Calcium Acetylcysteine and Mecobalamin Algal ... Levomefolate Calcium, Acetylcysteine, Mecobalamin and Algal …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Cough and Cold Preparations ... Amino Acids ... Amino Acids, Neutral ... Amino Acids, Sulfur …
Matched Products: … ALPAC Effervescent Tablet 600mg …
Matched Iupac: … (2R)-2-acetamido-3-sulfanylpropanoic acid …
Matched Description: … Acetylcysteine is an antioxidant and glutathione inducer indicated for mucolytic therapy and the treatment ... [A228158,A228163,A228168] Acetylcysteine was granted FDA approval on 14 September 1963.[L31488] …
Matched Mixtures name: … Levomefolate Calcium Acetylcysteine and Mecobalamin Algal ... Levomefolate Calcium, Acetylcysteine, Mecobalamin and Algal …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Cough and Cold Preparations ... Amino Acids ... Amino Acids, Neutral ... Amino Acids, Sulfur …
Matched Products: … ALPAC Effervescent Tablet 600mg …
Baclofen
Baclofen is a gamma-aminobutyric acid (GABA) agonist used as a skeletal muscle relaxant. Although originally designed in 1962 to treat epilepsy, baclofen was not effective in treating this condition but instead was shown to reduce spasticity in selected patients. Baclofen was reintroduced in 1971 as a treatment for spasticity and...
Approved
Matched Synonyms: … 4-Amino-3-(4-chlorophenyl)butyric acid ... DL-4-Amino-3-p-chlorophenylbutanoic acid ... beta-(Aminomethyl)-p-chlorohydrocinnamic acid …
Matched Iupac: … 4-amino-3-(4-chlorophenyl)butanoic acid …
Matched Description: … FDA in 1977. ... Baclofen is a gamma-aminobutyric acid (GABA) agonist used as a skeletal muscle relaxant. ... [A245338] Baclofen was reintroduced in 1971 as a treatment for spasticity and was later approved by the …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... gamma-Aminobutyric Acid-ergic Agonist …
Matched Iupac: … 4-amino-3-(4-chlorophenyl)butanoic acid …
Matched Description: … FDA in 1977. ... Baclofen is a gamma-aminobutyric acid (GABA) agonist used as a skeletal muscle relaxant. ... [A245338] Baclofen was reintroduced in 1971 as a treatment for spasticity and was later approved by the …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... gamma-Aminobutyric Acid-ergic Agonist …
Nifedipine
Nifedipine, or BAY a 1040, is a first generation dihydropyridine L-type calcium channel blocker, similar to nicardipine.[A190210,A190273,A175390,L11383] Nifedipine was developed by Bayer and first described in the literature, along with other dihydropyridines, in 1972.[A175390,A190276] Since nifedipine's development, second and third generation dihydropyridines have been developed with slower onsets and longer...
Approved
Matched Description: … developed with slower onsets and longer durations of action. ... [A190210,A190273,A175390,L11383] Nifedipine was developed by Bayer and first described in the literature ... [A175390,A190276] Since nifedipine's development, second and third generation dihydropyridines have been …
Matched Mixtures name: … Seaford Nifedipine and Lidocaine Hydrochloride Cream …
Matched Categories: … Calcium Channel Blockers and Diuretics ... Calcium-Regulating Hormones and Agents ... Beta blocking agents and calcium channel blockers ... atenolol and nifedipine ... nifedipine and diuretics …
Matched Products: … NIFEDIPIN ACIS 10MG RETARD ... NIFEDIPIN ACIS 20MG RETARD …
Matched Mixtures name: … Seaford Nifedipine and Lidocaine Hydrochloride Cream …
Matched Categories: … Calcium Channel Blockers and Diuretics ... Calcium-Regulating Hormones and Agents ... Beta blocking agents and calcium channel blockers ... atenolol and nifedipine ... nifedipine and diuretics …
Matched Products: … NIFEDIPIN ACIS 10MG RETARD ... NIFEDIPIN ACIS 20MG RETARD …
Gavorestat
Gavorestat is under investigation in clinical trial NCT04902781 (Clinical Benefit, Safety, PK and PD Study of AT-007 in Pediatric Subjects With Classic Galactosemia).
Investigational
Matched Synonyms: … Acid ... 2-(4-Oxo-3-((5-(Trifluoromethyl)Benzo[D]Thiazol-2-Yl)Methyl)-3,4-Dihydrothieno[3,4-D]Pyridazin-1-Yl)Acetic …
Matched Iupac: … -oxo-3-{[5-(trifluoromethyl)-1,3-benzothiazol-2-yl]methyl}-3H,4H-thieno[3,4-d]pyridazin-1-yl)acetic acid …
Matched Description: … Gavorestat is under investigation in clinical trial NCT04902781 (Clinical Benefit, Safety, PK and PD …
Matched Iupac: … -oxo-3-{[5-(trifluoromethyl)-1,3-benzothiazol-2-yl]methyl}-3H,4H-thieno[3,4-d]pyridazin-1-yl)acetic acid …
Matched Description: … Gavorestat is under investigation in clinical trial NCT04902781 (Clinical Benefit, Safety, PK and PD …
Lysine
Lysine (abbreviated as Lys or K) is an α-amino acid with the chemical formula HO2CCH(NH2)(CH2)4NH2. This amino acid is an essential amino acid, which means that humans cannot synthesize it. Its codons are AAA and AAG. Lysine is a base, as are arginine and histidine. The ε-amino group acts as...
Approved
Nutraceutical
Matched Synonyms: … Lysine acid ... (S)-2,6-diaminohexanoic acid ... (S)-α,ε-diaminocaproic acid …
Matched Iupac: … (2S)-2,6-diaminohexanoic acid …
Matched Description: … Its codons are AAA and AAG. Lysine is a base, as are arginine and histidine. ... This amino acid is an essential amino acid, which means that humans cannot synthesize it. ... The ε-amino group acts as a site for hydrogen binding and a general base in catalysis. …
Matched Mixtures name: … Aminosyn II and Dextrose ... Aminosyn II and Dextrose ... NUTROPLEX LIQUID WITH IRON AND LYSINE …
Matched Categories: … Amino Acids, Peptides, and Proteins ... arginine and lysine ... Blood and Blood Forming Organs ... Blood Substitutes and Perfusion Solutions ... Amino Acids …
Matched Iupac: … (2S)-2,6-diaminohexanoic acid …
Matched Description: … Its codons are AAA and AAG. Lysine is a base, as are arginine and histidine. ... This amino acid is an essential amino acid, which means that humans cannot synthesize it. ... The ε-amino group acts as a site for hydrogen binding and a general base in catalysis. …
Matched Mixtures name: … Aminosyn II and Dextrose ... Aminosyn II and Dextrose ... NUTROPLEX LIQUID WITH IRON AND LYSINE …
Matched Categories: … Amino Acids, Peptides, and Proteins ... arginine and lysine ... Blood and Blood Forming Organs ... Blood Substitutes and Perfusion Solutions ... Amino Acids …
2-[(7-HYDROXY-NAPHTHALEN-1-YL)-OXALYL-AMINO]-BENZOIC ACID
Experimental
Matched Name: … 2-[(7-HYDROXY-NAPHTHALEN-1-YL)-OXALYL-AMINO]-BENZOIC ACID …
Matched Iupac: … 2-[1-carboxy-N-(7-hydroxynaphthalen-1-yl)formamido]benzoic acid …
Matched Iupac: … 2-[1-carboxy-N-(7-hydroxynaphthalen-1-yl)formamido]benzoic acid …
2-({[4-bromo-3-(diethylsulfamoyl)phenyl]carbonyl}amino)benzoic acid
Experimental
Matched Name: … 2-({[4-bromo-3-(diethylsulfamoyl)phenyl]carbonyl}amino)benzoic acid …
Matched Iupac: … 2-[4-bromo-3-(diethylsulfamoyl)benzamido]benzoic acid …
Matched Iupac: … 2-[4-bromo-3-(diethylsulfamoyl)benzamido]benzoic acid …
2-[(2,4-DICHLOROBENZOYL)AMINO]-5-(PYRIMIDIN-2-YLOXY)BENZOIC ACID
Experimental
Matched Name: … 2-[(2,4-DICHLOROBENZOYL)AMINO]-5-(PYRIMIDIN-2-YLOXY)BENZOIC ACID …
Matched Iupac: … 2-(2,4-dichlorobenzamido)-5-(pyrimidin-2-yloxy)benzoic acid …
Matched Iupac: … 2-(2,4-dichlorobenzamido)-5-(pyrimidin-2-yloxy)benzoic acid …
Dodecyl sulfate
Experimental
Matched Synonyms: … Dodecylsulfuric acid ... Lauryl sulfuric acid ... Sulfuric acid, monododecyl ester …
Matched Iupac: … (dodecyloxy)sulfonic acid …
Matched Categories: … Sulfur Acids ... Sulfonic Acids ... Alkanesulfonic Acids …
Matched Iupac: … (dodecyloxy)sulfonic acid …
Matched Categories: … Sulfur Acids ... Sulfonic Acids ... Alkanesulfonic Acids …
Displaying drugs 1076 - 1100 of 3382 in total