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Displaying drugs 1076 - 1100 of 1529 in total
Mavacamten
Mavacamten is a myosin inhibitor indicated for the treatment of adults with symptomatic New York Heart Association (NYHA) class II-III obstructive hypertrophic cardiomyopathy (HCM). It received initial US FDA approval in 2022, and it is one of the first myosin inhibitors to be used in humans. Mavacamten was also approved...
Approved
Investigational
Benzydamine
Benzydamine (also known as Tantum Verde or Difflam), available as the hydrochloride salt, is a locally-acting nonsteroidal anti-inflammatory drug (NSAID) with local anaesthetic and analgesic properties. It is used topically for pain relief and anti-inflammatory treatment of the mouth, throat, or muscoskeletal system.
Although the indazole analogue benzydamine is a...
Approved
Apremilast
Apremilast, also known as Otezla, is a phosphodiesterase 4 (PDE4) inhibitor used to treat various types of symptoms resulting from certain inflammatory autoimmune diseases. It belongs to the same drug class as Roflumilast and Crisaborole.[A181244,L7495] Initially approved in 2014, it is marketed by Celgene. In July 2019, apremilast was granted...
Approved
Investigational
Peginterferon alfa-2b
Peginterferon alfa-2b is a form of recombinant interferon used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most...
Approved
Matched Description: … Peginterferon alfa-2b is a form of recombinant interferon used as part of combination therapy to treat …
Spironolactone
Spironolactone is a potassium-sparing diuretic. It binds to mineralocorticoid receptors and functions as aldosterone antagonists. It promotes sodium and water excretion and potassium retention. Spironolactone was originally developed purely for this ability before other pharmacodynamic properties of the drug were discovered.[A11837, A178246] It is indicated to treat several conditions, including...
Approved
1,6-Fructose Diphosphate (Linear Form)
Experimental
Matched Name: … 1,6-Fructose Diphosphate (Linear Form) …
Open Form of 2'-Deoxy-Ribofuranose-5'-Phosphate
Experimental
Matched Name: … Open Form of 2'-Deoxy-Ribofuranose-5'-Phosphate …
2-KETO-6-PHOSPHATE-D-GLUCONIC ACID, ALPHA-FURANOSE FORM
Experimental
Matched Name: … 2-KETO-6-PHOSPHATE-D-GLUCONIC ACID, ALPHA-FURANOSE FORM …
D-threo-neopterin
A pteridine derivative present in body fluids; elevated levels result from immune system activation, malignant disease, allograft rejection, and viral infections. (From Stedman, 26th ed) Neopterin also serves as a precursor in the biosynthesis of biopterin.
Experimental
Matched Synonyms: … Neopterin D-threo-form …
(R)-Gossypol
(R)-Gossypol is the R-isomer of Gossypol.
Investigational
Matched Synonyms: … Gossypol r-form …
Vanglusagene ensiparvovec
Investigational
Matched Synonyms: … capsid (AAV-Spark100) and a codon-optimized expression cassette to drive expression of a secretable form …
PRGN-3006
PRGN-3006 are autologous CD3+ T cells genetically modified using a non-viral system to express a CD33 CAR, membrane-bound interleukin-15, and a truncated form of human HER1T (kill switch) on the cell surface.
Investigational
Matched Synonyms: … modified using a non-viral system to express a CD33 CAR, membrane bound Interleukin-15, and a truncated form …
Matched Description: … modified using a non-viral system to express a CD33 CAR, membrane-bound interleukin-15, and a truncated form …
Matched Description: … modified using a non-viral system to express a CD33 CAR, membrane-bound interleukin-15, and a truncated form …
Porphobilinogen deaminase, human recombinant
Investigational
Matched Synonyms: … Recombinant human porphobilinogen deaminase, erythropoietic form …
Bevantolol
Bevantolol is a beta-1 adrenoceptor antagonist that has been shown to be as effective as other beta blockers for the treatment of angina pectoris and hypertension. Mechanism of Action Animal experiments confirm both agonist and antagonist effects on alpha-receptors, in addition to antagonist activity at beta-1 receptors.
Experimental
Matched Products: … BETA FORM …
5alpha-androstane-3beta,17alpha-diol
5alpha-androstane-3beta,17alpha-diol is the unspecified form of the steroid, normally a major metabolite of testosterone with androgenic activity. It has been implicated as a regulator of gonadotropin secretion.
Experimental
Matched Description: … 5alpha-androstane-3beta,17alpha-diol is the unspecified form of the steroid, normally a major metabolite …
Galactose-uridine-5'-diphosphate
A nucleoside diphosphate sugar which can be epimerized into UDPglucose for entry into the mainstream of carbohydrate metabolism. Serves as a source of galactose in the synthesis of lipopolysaccharides, cerebrosides, and lactose.
Experimental
Matched Description: … Serves as a source of galactose in the synthesis of lipopolysaccharides, cerebrosides, and lactose. …
Displaying drugs 1076 - 1100 of 1529 in total