Displaying drugs 1101 - 1125 of 1253 in total
Bisoprolol
Bisoprolol is a cardioselective β1-adrenergic blocking agent used to treat high blood pressure.[A180472,L7219] It is considered a potent drug with a long-half life that can be used once daily to reduce the need for multiple doses of antihypertensive drugs. Bisoprolol is generally well tolerated, likely due to its β1-adrenergic receptor...
Approved
Matched Synonyms: … (+-)-1-((alpha-(2-Isopropoxyethoxy)-p-tolyl)oxy)-3-(isopropylamino)-2-propanol …
Matched Description: … A180472] Bisoprolol is generally well tolerated, likely due to its β1-adrenergic receptor selectivity and ... alternative to non-selective β-blocker drugs in the treatment of hypertension such as [Carvedilol] and ... It may be used alone or in combination with other drugs to manage hypertension[L7219] and can be useful …
Matched Mixtures name: … Bisoprolol Fumarate and Hydrochlorothiazide ... Bisoprolol Fumarate and Hydrochlorothiazide ... Bisoprolol Fumarate and Hydrochlorothiazide …
Matched Categories: … Beta blocking agents and calcium channel blockers ... ramipril and bisoprolol ... bisoprolol and thiazides ... bisoprolol and amlodipine ... perindopril and bisoprolol …
Matched Description: … A180472] Bisoprolol is generally well tolerated, likely due to its β1-adrenergic receptor selectivity and ... alternative to non-selective β-blocker drugs in the treatment of hypertension such as [Carvedilol] and ... It may be used alone or in combination with other drugs to manage hypertension[L7219] and can be useful …
Matched Mixtures name: … Bisoprolol Fumarate and Hydrochlorothiazide ... Bisoprolol Fumarate and Hydrochlorothiazide ... Bisoprolol Fumarate and Hydrochlorothiazide …
Matched Categories: … Beta blocking agents and calcium channel blockers ... ramipril and bisoprolol ... bisoprolol and thiazides ... bisoprolol and amlodipine ... perindopril and bisoprolol …
Cystine
A covalently linked dimeric nonessential amino acid formed by the oxidation of cysteine. Two molecules of cysteine are joined together by a disulfide bridge to form cystine.
Approved
Nutraceutical
Matched Synonyms: … L-alpha-Diamino-beta-dithiolactic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
O1-Methyl-4-Deoxy-4-Thio-Alpha-D-Glucose
Experimental
Matched Name: … O1-Methyl-4-Deoxy-4-Thio-Alpha-D-Glucose …
Scopolamine
Scopolamine is a tropane alkaloid isolated from members of the Solanaceae family of plants, similar to atropine and hyoscyamine, all of which structurally mimic the natural neurotransmitter acetylcholine.[A228423, A228763] Scopolamine was first synthesized in 1959, but to date, synthesis remains less efficient than extracting scopolamine from plants. As an acetylcholine...
Approved
Investigational
Matched Synonyms: … 6-beta,7-beta-Epoxy-3-alpha-tropanyl S-(-)-tropate ... alpha-(Hydroxymethyl)benzeneacetic acid 9-methyl-3-oxa-9-azatricyclo(3.3.1.0(2.4))non-7-yl ester …
Matched Description: … nervous system and cholinergic signalling. ... vomiting associated with motion sickness and surgical procedures. ... available as both oral tablets and a transdermal delivery system. …
Matched Mixtures name: … Phenobarbital, Hyoscyamine Sulfate, Atropine Sulfate and Scopolamine Hydrobromide ... Phenobarbital, Hyoscyamine Sulfate, Atropine Sulfate and Scopolamine Hydrobromide …
Matched Categories: … Alimentary Tract and Metabolism ... Antiemetics and Antinauseants ... Hypnotics and Sedatives ... Mydriatics and Cycloplegics …
Matched Description: … nervous system and cholinergic signalling. ... vomiting associated with motion sickness and surgical procedures. ... available as both oral tablets and a transdermal delivery system. …
Matched Mixtures name: … Phenobarbital, Hyoscyamine Sulfate, Atropine Sulfate and Scopolamine Hydrobromide ... Phenobarbital, Hyoscyamine Sulfate, Atropine Sulfate and Scopolamine Hydrobromide …
Matched Categories: … Alimentary Tract and Metabolism ... Antiemetics and Antinauseants ... Hypnotics and Sedatives ... Mydriatics and Cycloplegics …
5-(PARA-NITROPHENYL PHOSPHONATE)-PENTANOIC ACID
Experimental
Matched Name: … 5-(PARA-NITROPHENYL PHOSPHONATE)-PENTANOIC ACID …
Matched Iupac: … 4-nitrophenyl (4-carboxybutyl)phosphonate …
Matched Iupac: … 4-nitrophenyl (4-carboxybutyl)phosphonate …
[(2-AMINO-ALPHA-METHOXYIMINO-4-THIAZOLYLACETYL)AMINO]METHYLBORONIC ACID
Experimental
Matched Name: … [(2-AMINO-ALPHA-METHOXYIMINO-4-THIAZOLYLACETYL)AMINO]METHYLBORONIC ACID …
Pravastatin
Pravastatin is the 6-alpha-hydroxy acid form of mevastatin. Pravastatin was firstly approved in 1991 becoming the second available statin in the United States. It was the first statin administered as the active form and not as a prodrug. This drug was developed by Sankyo Co. Ltd.; however, the first approved...
Approved
Matched Description: … Pravastatin is the 6-alpha-hydroxy acid form of [mevastatin]. ... It was the first statin administered as the active form and not as a prodrug. ... Ltd.; however, the first approved pravastatin product was developed by Bristol Myers Squibb and FDA approved …
Matched Categories: … pravastatin and ezetimibe ... pravastatin and fenofibrate ... pravastatin and acetylsalicylic acid ... pravastatin, ezetimibe and fenofibrate …
Matched Products: … COL-ALPHAR …
Matched Categories: … pravastatin and ezetimibe ... pravastatin and fenofibrate ... pravastatin and acetylsalicylic acid ... pravastatin, ezetimibe and fenofibrate …
Matched Products: … COL-ALPHAR …
Lutikizumab
Lutikizumab is under investigation in clinical trial NCT02087904 (A Study Evaluating the Safety, Efficacy, and Pharmacodynamic Effects of ABT-981 in Patients With Knee Osteoarthritis).
Investigational
Matched Synonyms: … /interleukin 1.alpha.) …
Matched Description: … Lutikizumab is under investigation in clinical trial NCT02087904 (A Study Evaluating the Safety, Efficacy, and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … Lutikizumab is under investigation in clinical trial NCT02087904 (A Study Evaluating the Safety, Efficacy, and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Mefloquine
Malaria is a protozoan disease that places an enormous burden on human health in endemic areas around the world. The 2020 World Health Organization malaria report indicates a 60% decrease in the global malaria fatality rate between 2000 to 2019. Despite this, malaria remains a significant cause of morbidity and...
Approved
Investigational
Matched Synonyms: … alpha-2-Piperidinyl-2,8-bis(trifluoromethyl)-4-quinolinemethanol …
Matched Description: … Eastern Africa, nonimmune civilian and military travelers, pregnant women, and immigrants traveling ... It was approved by the FDA in 1989, and was first marketed by Hoffman Laroche. ... treatment of malaria caused by infection with Plasmodium vivax and Plasmodium falciparum. …
Matched Categories: … artesunate and mefloquine ... Antiparasitic Products, Insecticides and Repellents …
Matched Description: … Eastern Africa, nonimmune civilian and military travelers, pregnant women, and immigrants traveling ... It was approved by the FDA in 1989, and was first marketed by Hoffman Laroche. ... treatment of malaria caused by infection with Plasmodium vivax and Plasmodium falciparum. …
Matched Categories: … artesunate and mefloquine ... Antiparasitic Products, Insecticides and Repellents …
Hydroxyprogesterone caproate
Hydroxyprogesterone caproate is a synthetic steroid hormone that is similar to medroxyprogesterone acetate and megestrol acetate. It is an ester derivative of 17α-hydroxyprogesterone formed from caproic acid (hexanoic acid). Hydroxyprogesterone caproate was previously marketed under the trade name Delalutin by Squibb, which was approved by the U.S. Food and Drug...
Approved
Investigational
Matched Synonyms: … 17-alpha-hydroxy-progesterone caproate …
Matched Description: … and megestrol acetate. ... Food and Drug Administration (FDA) in 1956 and withdrawn from marketing in 1999.[L46118] The U.S. ... In April 2023, the FDA withdrew its approval of Makena and its generics given an unfavorable risk-to-benefit …
Matched Categories: … Progesterone and Derivatives ... Combination Contraceptives (with Estrogen and derivatives) ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Description: … and megestrol acetate. ... Food and Drug Administration (FDA) in 1956 and withdrawn from marketing in 1999.[L46118] The U.S. ... In April 2023, the FDA withdrew its approval of Makena and its generics given an unfavorable risk-to-benefit …
Matched Categories: … Progesterone and Derivatives ... Combination Contraceptives (with Estrogen and derivatives) ... Hormones, Hormone Substitutes, and Hormone Antagonists …
TP-1287
Investigational
Matched Synonyms: … chlorophenyl)-5-hydroxy-8-((3S,4R)-3-hydroxy-1-methylpiperidin-4-yl)-4-oxo-4H-chromen-7-yl dihydrogen phosphate …
AR-42
AR-42 has been used in trials studying the treatment of Meningioma, Acoustic Neuroma, Testicular Lymphoma, Intraocular Lymphoma, and Vestibular Schwannoma, among others.
Investigational
Matched Synonyms: … BENZENEACETAMIDE, N-(4-((HYDROXYAMINO)CARBONYL)PHENYL)-.ALPHA.-(1-METHYLETHYL)-, (.ALPHA.S)- …
Matched Description: … studying the treatment of Meningioma, Acoustic Neuroma, Testicular Lymphoma, Intraocular Lymphoma, and …
Matched Description: … studying the treatment of Meningioma, Acoustic Neuroma, Testicular Lymphoma, Intraocular Lymphoma, and …
Clervonafusp alfa
Investigational
Matched Synonyms: … fragment targeting the equilibrative nucleoside transporter 2 (ent2), fused with a human lysosomal .alpha ... Immunoglobulin g1, (humanized monoclonal 3e10 .gamma.1-chain fab fragment) fusion protein with 67-952-lysosomal .alpha …
Inolimomab
Inolimomab is under investigation as an agent to treat steroid-resistant graft vs host disease. It has thus far offered similar efficacy to other monoclonal antibody options, though it may carry a higher risk of infections.
Investigational
Matched Synonyms: … Immunoglobulin G1, anti-(human interleukin 2 receptor alpha-chain) (mouse monoclonal B-B10 gammal-chain …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Mirvetuximab
Investigational
Matched Synonyms: … Immunoglobulin g1, anti-(human folate receptor .alpha.) …
Entacapone
Entacapone is a selective, reversible catechol-O-methyl transferase (COMT) inhibitor for the treatment of Parkinson's disease. It is a member of the class of nitrocatechols. When administered concomittantly with levodopa and a decarboxylase inhibitor (e.g., carbidopa), increased and more sustained plasma levodopa concentrations are reached as compared to the administration of...
Approved
Investigational
Matched Synonyms: … (E)-alpha-Cyano-N,N-diethyl-3,4-dihydroxy-5-nitrocinnamamide …
Matched Description: … and a decarboxylase inhibitor. ... When administered concomittantly with levodopa and a decarboxylase inhibitor (e.g., carbidopa), increased ... and more sustained plasma levodopa concentrations are reached as compared to the administration of levodopa …
Matched Mixtures name: … Carbidopa, Levodopa and Entacapone ... Carbidopa, Levodopa and Entacapone ... Carbidopa, Levodopa and Entacapone …
Matched Description: … and a decarboxylase inhibitor. ... When administered concomittantly with levodopa and a decarboxylase inhibitor (e.g., carbidopa), increased ... and more sustained plasma levodopa concentrations are reached as compared to the administration of levodopa …
Matched Mixtures name: … Carbidopa, Levodopa and Entacapone ... Carbidopa, Levodopa and Entacapone ... Carbidopa, Levodopa and Entacapone …
BR-007
Investigational
Matched Synonyms: … -4H-pyrrolo[1,2-b]pyrazol-3-yl)quinolin-7-yl)oxy)ethoxy)carbonyl)amino)butane-1,1-diyl)bis(hydrogen phosphonate …
D-Gluco-2,5-Anhydro-1-Deoxy-1-Phosphonohexitol-6-Phosphate
Experimental
Matched Name: … D-Gluco-2,5-Anhydro-1-Deoxy-1-Phosphonohexitol-6-Phosphate …
1,2-Di-1-(3,7,11,15-Tetramethyl-Hexadecane)-Sn-Glycero-3-Phosphate
Experimental
Matched Name: … 1,2-Di-1-(3,7,11,15-Tetramethyl-Hexadecane)-Sn-Glycero-3-Phosphate …
Streptomycin
Streptomycin, an antibiotic derived from Streptomyces griseus, was the first aminoglycoside to be discovered and used in practice in the 1940s.[A233325,A233390] Selman Waksman and eventually Albert Schatz were recognized with the Nobel Prize in Medicine for their discovery of streptomycin and its antibacterial activity.[A233325,A232294] Although streptomycin was the first antibiotic...
Approved
Vet approved
Matched Synonyms: … 2,4-diguanidino-3,5,6-trihydroxycyclohexyl 5-deoxy-2-O-(2-deoxy-2-methylamino-alpha-L-glucopyranosyl) …
Matched Description: … Medicine for their discovery of streptomycin and its antibacterial activity. ... Streptomycin, an antibiotic derived from _Streptomyces griseus_, was the first aminoglycoside to be discovered and ... [A233325,A233390] Selman Waksman and eventually Albert Schatz were recognized with the Nobel Prize in …
Matched Categories: … Alimentary Tract and Metabolism ... streptomycin and isoniazid …
Matched Description: … Medicine for their discovery of streptomycin and its antibacterial activity. ... Streptomycin, an antibiotic derived from _Streptomyces griseus_, was the first aminoglycoside to be discovered and ... [A233325,A233390] Selman Waksman and eventually Albert Schatz were recognized with the Nobel Prize in …
Matched Categories: … Alimentary Tract and Metabolism ... streptomycin and isoniazid …
Fenbendazole
Fenbendazole is a benzimidazole that presents a wide spectrum anthelmintic effect. It is used against a number of gastrointestinal parasites including giardia, roundworms, hookworms, whipworms, the Taenia genus of tapeworms, pinworms, aelurostrongylus, paragonimiasis, strongyles, and Strongyloides. Fenbendazole is approved to be administered under veterinary to sheep, cattle, horses, fish, dogs,...
Vet approved
Matched Synonyms: … Methyl [5-(phenylthio)-1H-benzimidazol-2-yl]carbamate …
Matched Iupac: … methyl N-[5-(phenylsulfanyl)-1H-1,3-benzodiazol-2-yl]carbamate …
Matched Description: … , whipworms, the Taenia genus of tapeworms, pinworms, aelurostrongylus, paragonimiasis, strongyles, and ... is approved to be administered under veterinary to sheep, cattle, horses, fish, dogs, cats, rabbits and …
Matched Categories: … Antiparasitic Products, Insecticides and Repellents …
Matched Iupac: … methyl N-[5-(phenylsulfanyl)-1H-1,3-benzodiazol-2-yl]carbamate …
Matched Description: … , whipworms, the Taenia genus of tapeworms, pinworms, aelurostrongylus, paragonimiasis, strongyles, and ... is approved to be administered under veterinary to sheep, cattle, horses, fish, dogs, cats, rabbits and …
Matched Categories: … Antiparasitic Products, Insecticides and Repellents …
Prostaglandin D2
The principal cyclooxygenase metabolite of arachidonic acid. It is released upon activation of mast cells and is also synthesized by alveolar macrophages. Among its many biological actions, the most important are its bronchoconstrictor, platelet-activating-factor-inhibitory, and cytotoxic effects.
Investigational
Matched Synonyms: … 11-Dehydroprostaglandin F2-alpha …
Matched Description: … It is released upon activation of mast cells and is also synthesized by alveolar macrophages. ... biological actions, the most important are its bronchoconstrictor, platelet-activating-factor-inhibitory, and …
Matched Description: … It is released upon activation of mast cells and is also synthesized by alveolar macrophages. ... biological actions, the most important are its bronchoconstrictor, platelet-activating-factor-inhibitory, and …
1-(O-Carboxy-Phenylamino)-1-Deoxy-D-Ribulose-5-Phosphate
Experimental
Matched Name: … 1-(O-Carboxy-Phenylamino)-1-Deoxy-D-Ribulose-5-Phosphate …
2'-deoxy-N-(naphthalen-1-ylmethyl)guanosine 5'-(dihydrogen phosphate)
Experimental
Matched Name: … 2'-deoxy-N-(naphthalen-1-ylmethyl)guanosine 5'-(dihydrogen phosphate) …
Displaying drugs 1101 - 1125 of 1253 in total