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Displaying drugs 11276 - 11300 of 13506 in total
Intermedine
Investigational
Matched Synonyms: … N-acetyl-acth(1-13)-amide …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Atibuclimab
Atibuclimab (IC14) is a chimeric CD14 antibody investigated for the treatment of patients with severe sepsis.
Investigational
Fenthion
Fenthion is an organothiophosphate drug used as an insecticide, avicide, and acaricide. Its mode of action is explained by cholinesterase enzyme inhibition, which is similar to other organophosphates. Fenthion is listed as a restricted use compound by the United States Environmental Protection Agency due to its potential to cause cholinesterase...
Vet approved
Matched Synonyms: … 4-methylmercapto-3-Methylphenyl dimethyl thiophosphate ... O,O-Dimethyl O-[3-methyl-4-(methylsulfanyl)phenyl] thiophosphate ... O,O-Dimethyl-O-4-(methylmercapto)-3-methylphenyl thiophosphate …
Matched Iupac: … O,O-dimethyl O-3-methyl-4-(methylsulfanyl)phenyl phosphorothioate …
Matched Iupac: … O,O-dimethyl O-3-methyl-4-(methylsulfanyl)phenyl phosphorothioate …
Escherichia coli strain Nissle 1917
Experimental
Di-Stearoyl-3-Sn-Phosphatidylcholine
Experimental
Matched Name: … Di-Stearoyl-3-Sn-Phosphatidylcholine …
Matched Iupac: … [(2R)-2,3-bis(octadecanoyloxy)propoxy][2-(trimethylazaniumyl)ethoxy]phosphinic acid …
Matched Iupac: … [(2R)-2,3-bis(octadecanoyloxy)propoxy][2-(trimethylazaniumyl)ethoxy]phosphinic acid …
Uprosertib
Uprosertib has been used in trials studying the treatment of Cancer, Melanoma, Solid Tumours, Cervical Cancer, and HER2/Neu Negative, among others.
Investigational
Matched Iupac: … N-[(2S)-1-amino-3-(3,4-difluorophenyl)propan-2-yl]-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)furan ... -2-carboxamide …
Matched Salts cas: … 1047635-80-2 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Salts cas: … 1047635-80-2 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Rose bengal lactone
Experimental
Matched Iupac: … 4,5,6,7-tetrachloro-3',6'-dihydroxy-2',4',5',7'-tetraiodo-3H-spiro[2-benzofuran-1,9'-xanthen]-3-one …
BACTEK-R
MV130 contains different components of whole heat-inactivated gram-positive and -negative bacteria that are involved in upper and lower respiratory infections. These include streptococcus pneumoniae and staphylococcus aureus. Though studies have shown that it reduces the rate of infections in recurrent respiratory tract infections (RRTIs), the complete mechanisms are not fully...
Investigational
Becotatug
Becotatug is under investigation in clinical trial NCT06380348 (JMT101 in Combination With Osimertinib, Versus Cisplatin-pemetrexed in Participants With Locally Advanced or Metastatic Non-small Cell Lung Cancer (NSCLC) Characterized by Epithermal Growth Factor Receptor (EGFR) Exon 20ins Mutations).
Investigational
Ethyl Oxo(Piperidin-1-Yl)Acetate
Experimental
Matched Name: … Ethyl Oxo(Piperidin-1-Yl)Acetate …
Matched Iupac: … ethyl 2-oxo-2-(piperidin-1-yl)acetate …
Matched Iupac: … ethyl 2-oxo-2-(piperidin-1-yl)acetate …
Alpha-D-Glucose 1,6-Bisphosphate
Experimental
Matched Iupac: … {[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[(phosphonooxy)methyl]oxan-2-yl]oxy}phosphonic acid …
1-Hexadecanosulfonyl-O-L-Serine
Experimental
Matched Name: … 1-Hexadecanosulfonyl-O-L-Serine …
Matched Iupac: … (2S)-2-amino-3-[(hexadecane-1-sulfonyl)oxy]propanoic acid …
Matched Iupac: … (2S)-2-amino-3-[(hexadecane-1-sulfonyl)oxy]propanoic acid …
COVID19 s-vax loaded autologous dendritic cell vaccine
Dendritic cells (DCs) can be derived and differentiated from peripheral blood mononuclear cells in the presence of specific cytokines and growth factors. These cells are then loaded with antigens produced by a virus or tumor cell and administered as a vaccine.
Dendritic Cells (DCs) are showing potential as natural adjuvants...
Investigational
Matched Description: … The rationale is that loading a DC cell with SARS-Cov-2 antigens and administering it as a vaccine can …
Donanemab
Donanemab (LY3002813) is a humanized IgG1 monoclonal antibody targeted against an epitope at the N-terminal of a specific type of amyloid beta (Aβ) - pyroglutamate Aβ - which is found only in the brain amyloid plaques associated with Alzheimer's Disease (AD). It works by inducing microglial-mediated clearance of existing Aβ...
Investigational
Matched Description: … [A232234,L32719]
In March 2021, Eli Lilly announced an expanded trial, named TRAILBLAZER-ALZ 2, which …
Orvepitant
Orvepitant has been used in trials studying the treatment of Depressive Disorder, Depressive Disorder, Major, Post-Traumatic Stress Disorder, and Posttraumatic Stress Disorder (PTSD).
Investigational
Matched Iupac: … ]ethyl]-2-(4-fluoro-2-methylphenyl)-N-methylpiperidine-1-carboxamide ... (2R,4S)-4-[(8aS)-6-oxo-octahydropyrrolo[1,2-a]pyrazin-2-yl]-N-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Pf-04531083
Pf-04531083 has been investigated for the treatment of Pain and Chronic Pain.
Investigational
Matched Iupac: … N-[6-amino-5-(2-chloro-5-methoxyphenyl)pyridin-2-yl]-1-methyl-1H-pyrazole-5-carboxamide …
Propyl Gallate
Propyl Gallate is under investigation in clinical trial NCT01450098 (A Study of LY2484595 in Healthy Subjects).
Investigational
OptPA
Optimized tPA (OptPA; W253R/R275S-tPA) is an engineered variant of tPA designed to exhibit reduced neurotoxicity.
Investigational
Tivirapine
Experimental
Matched Iupac: … (11S)-7-chloro-11-methyl-10-(3-methylbut-2-en-1-yl)-1,3,10-triazatricyclo[6.4.1.0^{4,13}]trideca-4(13 ... ),5,7-triene-2-thione …
Volrubigene ralaparvovec
Volrubigene ralaparvovec is under investigation in clinical trial NCT03223194 (Gene Transfer Clinical Study in Crigler-najjar Syndrome).
Investigational
Ulenistamab
Investigational
Matched Synonyms: … (human pancreatic adenocarcinoma up-regulated factor) (human-mus musculus monoclonal pbp1510 .gamma.1- …
Displaying drugs 11276 - 11300 of 13506 in total