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Displaying drugs 11376 - 11400 of 13885 in total

3,6,9,12,15-PENTAOXATRICOSAN-1-OL

Experimental

Broxyquinoline

Experimental
Matched Categories: … Heterocyclic Compounds, 2-Ring …

3,6,9,12,15-Pentaoxaheptadecane

Experimental

3-(Mercaptomethylene)Pyridine

Experimental
Matched Name: … 3-(Mercaptomethylene)Pyridine …
Matched Iupac: … (pyridin-3-yl)methanethiol …

Vadastuximab talirine

Vadastuximab Talirine has been used in trials studying the treatment of Acute myeloid leukemia, Myelodysplastic Syndrome, Acute Myelogenous Leukemia, and Acute Promyelocytic Leukemia.
Investigational
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Rovalpituzumab tesirine

Rovalpituzumab Tesirine has been used in trials studying the treatment of GLIOBLASTOMA, Malignant Melanoma, Other Solid Tumors, Small Cell Lung Cancer, and Medullary Thyroid Cancer, among others.
Investigational
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Cloricromen

Experimental
Matched Iupac: … ethyl 2-({8-chloro-3-[2-(diethylamino)ethyl]-4-methyl-2-oxo-2H-chromen-7-yl}oxy)acetate …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Odanacatib

Odanacatib is an inhibiter of cathepsin K which was originally developed be Merck & Co as a new treatment for osteoporosis . The drug made it to phase III trials before abandoned due to increased stroke.
Investigational
Matched Iupac: … (2S)-N-(1-cyanocyclopropyl)-4-fluoro-4-methyl-2-{[(1S)-2,2,2-trifluoro-1-{4'-methanesulfonyl-[1,1'-biphenyl …

DERIVATIVE OF AKLANONIC ACID METHYL ESTER (AAME)

Experimental
Matched Iupac: … methyl 2-{3-[(1R,3S)-1,3-dihydroxypentyl]-4,5-dihydroxy-9,10-dioxo-9,10-dihydroanthracen-2-yl}acetate …

4-HYDROXY-N'-(4-ISOPROPYLBENZYL)BENZOHYDRAZIDE

Experimental
Matched Iupac: … 4-hydroxy-N'-{[4-(propan-2-yl)phenyl]methyl}benzohydrazide …

Ganetespib

Ganetespib is under investigation for the treatment of BREAST CANCER, Small Cell Lung Cancer, Acute Myeloid Leukaemia, and Myelodysplastic Syndrome.
Investigational
Matched Iupac: … 3-[2,4-dihydroxy-5-(propan-2-yl)phenyl]-4-(1-methyl-1H-indol-5-yl)-4,5-dihydro-1H-1,2,4-triazol-5-one …

Oxiracetam

Experimental
Matched Iupac: … 2-(4-hydroxy-2-oxopyrrolidin-1-yl)acetamide …

Ladiratuzumab vedotin

Ladiratuzumab vedotin is under investigation in clinical trial NCT01969643 (A Safety Study of SGN-LIV1A in Breast Cancer Patients).
Investigational

(Z,Z)-4-Hydroxy-N,N,N-Trimethyl-10-Oxo-7-[(1-Oxo-9-Octadecenyl)Oxy]-3,5,9-Trioxa-4-Phosphaheptacos-18-En-1-Aminium-4-Oxide

Experimental
Matched Iupac: … [(2R)-2,3-bis[(9Z)-octadec-9-enoyloxy]propoxy][2-(trimethylazaniumyl)ethoxy]phosphinic acid …

Phenylalanine-N-Sulfonamide

Experimental
Matched Iupac: … (2S)-3-phenyl-2-(sulfamoylamino)propanoic acid …

Sambucus nigra flowering top

Experimental

6-Chloropurine Riboside, 5'-Monophosphate

Experimental
Matched Name: … 6-Chloropurine Riboside, 5'-Monophosphate …
Matched Iupac: … 6-chloro-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-[(phosphonooxy)methyl]oxolan-2-yl]-9H-purin-1-ium …

Relacatib

Investigational
Matched Iupac: … (2S)-2-[(1-benzofuran-2-yl)formamido]-4-methyl-N-[(4S,7R)-7-methyl-3-oxo-1-(pyridine-2-sulfonyl)azepan …

Telinavir

Telinavir has been used in trials studying the treatment of HIV Infections.
Investigational
Matched Iupac: … (2S)-N-[(2S,3R)-4-[(tert-butylcarbamoyl)(2-methylpropyl)amino]-3-hydroxy-1-phenylbutan-2-yl]-2-[(quinolin ... -2-yl)formamido]butanediamide …

Abafungin

Investigational
Matched Iupac: … N-{4-[2-(2,4-dimethylphenoxy)phenyl]-1,3-thiazol-2-yl}-1,3-diazinan-2-imine …

AZD-6280

AZD6280 has been used in trials studying the basic science of Anxiety.
Investigational
Matched Iupac: … 4-amino-8-(2,5-dimethoxyphenyl)-N-propylcinnoline-3-carboxamide …

Phenserine

Phenserine is under development by Axonyx, a US biopharmaceutical company that focuses on treatments for dementia. Phenserine is a next generation acetylcholinesterase (AChE) inhibitor indicated for the treatment of AD. Unlike currently marketed AChE inhibitors, it has a dual mechanism of action that also includes anti-amyloid activity, which may confer...
Investigational
Matched Iupac: … (3aS,8aR)-1,3a,8-trimethyl-1H,2H,3H,3aH,8H,8aH-pyrrolo[2,3-b]indol-5-yl N-phenylcarbamate …
Matched Description: … Axonyx announced on 20 September 2005 that phenserine was ineffective in two curtailed phase 3 trials …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Nitrocefin

Nitrocefin is a chromogenic cephalosporin substrate used to detect the presence of beta-lactamase enzymes, an important mediator of bacterial antibiotic resistance. While other detection methods exist, such as PCR, nitrocefin allows for rapid detection using few materials and inexpensive equipment.
Experimental
Matched Iupac: … (6R,7R)-3-[(E)-2-(2,4-dinitrophenyl)ethenyl]-8-oxo-7-[2-(thiophen-2-yl)acetamido]-5-thia-1-azabicyclo ... [4.2.0]oct-2-ene-2-carboxylic acid …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Abexinostat

Abexinostat has been used in trials studying the treatment of Sarcoma, Lymphoma, Leukemia, Lymphocytic, and Hodgkin Disease, among others. It is a novel, broad-spectrum hydroxamic acid-based inhibitor of histone deacetylase (HDAC) with potential antineoplastic activity.
Investigational
Matched Iupac: … 3-[(dimethylamino)methyl]-N-{2-[4-(hydroxycarbamoyl)phenoxy]ethyl}-1-benzofuran-2-carboxamide …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Omipalisib

Omipalisib has been used in trials studying the treatment of CANCER, Solid Tumours, and Idiopathic Pulmonary Fibrosis.
Investigational
Matched Iupac: … 2,4-difluoro-N-{2-methoxy-5-[4-(pyridazin-4-yl)quinolin-6-yl]pyridin-3-yl}benzene-1-sulfonamide …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Phosphatidylinositol 3-Kinases, antagonists & inhibitors …
Displaying drugs 11376 - 11400 of 13885 in total