Displaying drugs 11401 - 11425 of 12861 in total
Piprozolin
Experimental
Matched Iupac: … ethyl 2-[(2Z)-3-ethyl-4-oxo-5-(piperidin-1-yl)-1,3-thiazolidin-2-ylidene]acetate …
Tibezonium iodide
Experimental
Matched Iupac: … diethyl(methyl)[2-({4-[4-(phenylsulfanyl)phenyl]-3H-1,5-benzodiazepin-2-yl}sulfanyl)ethyl]azanium iodide …
Enarodustat
Enarodustat is under investigation in clinical trial NCT02581124 (Study to Evaluate Effect of Lapatinib on Pharmacokinetics of JTZ-951 in Subjects With End-stage Renal Disease).
Investigational
Matched Iupac: … 2-{[7-hydroxy-5-(2-phenylethyl)-[1,2,4]triazolo[1,5-a]pyridin-8-yl]formamido}acetic acid …
ABX-1431
ABX-1431 is under investigation in clinical trial NCT03625453 (Study of ABX-1431 in Adult Patients With Tourette Syndrome or Chronic Motor Tic Disorder).
Investigational
Matched Iupac: … 1,1,1,3,3,3-hexafluoropropan-2-yl 4-{[2-(pyrrolidin-1-yl)-4-(trifluoromethyl)phenyl]methyl}piperazine …
N-(5'-Phosphopyridoxyl)-D-Alanine
Experimental
Matched Iupac: … (2R)-2-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)amino]propanoic acid …
4'-Deoxy-4'-Acetylyamino-Pyridoxal-5'-Phosphate
Experimental
Matched Iupac: … 2-{[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)amino]oxy}acetic acid …
Phosphatidyl ethanol
Experimental
Matched Iupac: … [(2S)-2-[(9Z)-hexadec-9-enoyloxy]-3-[(9Z)-octadec-9-enoyloxy]propoxy](2-hydroxyethoxy)phosphinic acid …
TBC-3711
TBC3711 is a next-generation endothelin antagonist that is being studied through oral and intravenous formulations by Encysive Pharmaceuticals.
Investigational
Matched Iupac: … N-(2-acetyl-4,6-dimethylphenyl)-3-[(3,4-dimethyl-1,2-oxazol-5-yl)sulfamoyl]thiophene-2-carboxamide …
Odiparcil
Investigational
Matched Iupac: … 4-methyl-7-{[(2R,3R,4S,5S)-3,4,5-trihydroxythian-2-yl]oxy}-2H-chromen-2-one …
Demexiptiline
Demexiptiline is marketed under the names Deparon or Tinoran. It is a tricyclic antidepressant which acts primarily as a norepinephrine reuptake inhibitor.
Experimental
Matched Iupac: … methyl({2-[({tricyclo[9.4.0.0^{3,8}]pentadeca-1(15),3,5,7,9,11,13-heptaen-2-ylidene}amino)oxy]ethyl}) …
Matched Salts cas: … 18059-99-9 …
Matched Salts cas: … 18059-99-9 …
BI-671800
Bi 671800 has been used in trials studying the treatment of Asthma and Rhinitis, Allergic, Perennial.
Investigational
Matched Iupac: … 2-[4,6-bis(dimethylamino)-2-({4-[4-(trifluoromethyl)benzamido]phenyl}methyl)pyrimidin-5-yl]acetic acid …
Imipramine oxide
Experimental
Matched Iupac: … 3-{2-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(15),3,5,7,11,13-hexaen-2-yl}-N,N-dimethylpropanamine oxide …
Bisoxatin acetate
Experimental
Matched Iupac: … 4-{2-[4-(acetyloxy)phenyl]-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl}phenyl acetate …
DCFBC F-18
DCFBC F-18 is under investigation in clinical trial NCT02190279 (18F-DCFBC PET/CT in Prostate Cancer).
Investigational
Matched Iupac: … (2S)-2-({[(1R)-1-carboxy-2-({[4-(¹⁸F)fluorophenyl]methyl}sulfanyl)ethyl]carbamoyl}amino)pentanedioic …
Emprumapimod
Emprumapimod is a potent, orally active and selective inhibitor of p38α mitogen-activated kinase inhibitor. It was investigated for dilated cardiomyopathy.
Investigational
Matched Iupac: … (2S)-2-{[5-(2,4-difluorophenoxy)-1-(2-methylpropyl)-1H-indazol-6-yl]formamido}-4-(dimethylamino)butanamide …
PNU177836
Experimental
Matched Iupac: … 5-[(2S,3R)-2-{[(1S,2S)-2-{[(S)-(tert-butoxy)(hydroxy)methyl]amino}-1-hydroxy-3-phenylpropyl]amino}-3- ... hydroxy-3-(pentylamino)propyl]-2-(carboxymethoxy)benzoic acid …
Brivanib alaninate
Brivanib alaninate has been investigated for the treatment of Colorectal Cancer.
Investigational
Matched Iupac: … -2-yl (2S)-2-aminopropanoate ... (2R)-1-({4-[(4-fluoro-2-methyl-1H-indol-5-yl)oxy]-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yl}oxy)propan …
AZD-8165
AZD-8165 is under investigation in clinical trial NCT01150812 (Oral AZD8165 After Single Oral Ascending Doses in Healthy Male Subjects).
Investigational
Matched Iupac: … (1R)-2-[(5S)-5-({[5-chloro-2-(1H-1,2,3,4-tetrazol-1-yl)phenyl]methyl}carbamoyl)-4,5-dihydro-1H-pyrazol ... -1-yl]-1-(4-fluorophenyl)-2-oxoethyl propanoate …
(4-Hydroxymaltosephenyl)Glycine
Experimental
Matched Iupac: … -6-(hydroxymethyl)oxan-2-yl]oxy}oxan-2-yl]oxy}phenyl)acetic acid ... (2S)-2-amino-2-(4-{[(2R,3S,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-{[(2R,3S,4S,5S,6R)-3,4,5-trihydroxy …
SR 140333
SR 140333 is tachykinin antagonist which has potential to treat diarrhoea due to food allergy or inflammatory bowel disease.
Investigational
Matched Iupac: … 1-{2-[(3R)-3-(3,4-dichlorophenyl)-1-{2-[3-(propan-2-yloxy)phenyl]acetyl}piperidin-3-yl]ethyl}-4-phenyl …
Anamorelin
Investigational
Matched Iupac: … yl)-1-oxopropan-2-yl]-2-methylpropanamide ... 2-amino-N-[(2R)-1-[(3R)-3-benzyl-3-(N,N',N'-trimethylhydrazinecarbonyl)piperidin-1-yl]-3-(1H-indol-3- …
ONT-093
ONT-093 is an orally bioavailable inhibitor of P-glycoprotein (P-gp). In pre-clinical studies, ONT-093 could inhibit P-gp and reverse multidrug resistance at nM concentrations with no effect on paclitaxel pharmacokinetics.
Investigational
Matched Iupac: … -2-yl)aniline ... 4-(2-{4-[(1E)-3-ethoxyprop-1-en-1-yl]phenyl}-4-{4-[(propan-2-yl)amino]phenyl}-1H-imidazol-5-yl)-N-(propan …
Antipain
Antipain is a serine/cysteine protease inhibitor originally isolated from various strains of actinomycetes. Early studies investigated the potential for antipain to alter DNA damage and chromosomal aberrations in irradiated cells or those treated with chemical mutagens such as N-methyl-N'-nitro-N-nitrosoguanidine (MNNG).[A214484, A214487]
Antipain was used in 2010 to obtain a crystal...
Experimental
Matched Iupac: … (2S)-2-({[(1S)-4-carbamimidamido-1-{[(1S)-1-{[(2S)-5-carbamimidamido-1-oxopentan-2-yl]carbamoyl}-2-methylpropyl …
S-Hydroxymethyl Glutathione
Experimental
Matched Iupac: … (2S)-2-amino-4-{[(1R)-1-[(carboxymethyl)carbamoyl]-2-[(hydroxymethyl)sulfanyl]ethyl]carbamoyl}butanoic …
GLUTATHIONE SULFINATE
Experimental
Matched Iupac: … (2S)-2-amino-4-{[(1R)-1-[(carboxymethyl)carbamoyl]-2-[(S)-sulfino]ethyl]carbamoyl}butanoic acid …
Displaying drugs 11401 - 11425 of 12861 in total