Displaying drugs 11401 - 11425 of 12129 in total
Depatuxizumab mafodotin
Depatuxizumab/Denintuzumab mafodotin has been used in trials studying the treatment of Lymphoma, Gliosarcoma, Glioblastoma, Malignant Glioma, Squamous Cell Tumors, and Glioblastoma Multiforme.
Investigational
Chlorophyll B
A light, silvery, metallic element. It has the atomic symbol Mg, atomic number 12, and atomic weight 24.31. Its salts are essential in nutrition, being required for the activity of many enzymes, especially those concerned with oxidative phosphorylation. It is a component of both intra- and extracellular fluids and is...
Experimental
Matched Description: … A light, silvery, metallic element. ... It is a component of both intra- and extracellular fluids and is excreted in the urine and feces. …
MPI-674
MPI-674 is an aromatase inhibitor (AI) with a well-established, multi-year chronic safety and tolerability profile. AIs are a class of drugs that reduce the amount of estrogen circulating in the body by binding to and inhibiting the enzyme aromatase, which is responsible for converting certain hormones to estrogen. It is...
Investigational
Matched Description: … MPI-674 is an aromatase inhibitor (AI) with a well-established, multi-year chronic safety and tolerability ... AIs are a class of drugs that reduce the amount of estrogen circulating in the body by binding to and …
LNP-nCoVsaRNA Vaccine
LNP-nCoVsaRNA is a purified, synthetic mRNA vaccine candidate encoding the S glycoprotein of SARS-CoV-2, which is used primarily by the virus to attach to and invade human cells. The vaccine was developed in and tested by the Medical Research Council Clinical Trials Unit at UCL in the UK, and jointly...
Investigational
Matched Description: … LNP-nCoVsaRNA is a purified, synthetic mRNA vaccine candidate encoding the S glycoprotein of SARS-CoV ... As of July 2020, a clinical trial (COVAC1) is underway (ISRCTN17072692) to test the safety and immunogenicity …
MB07811
MB07811 is the first of a novel class of product candidates discovered by Metabasis designed to lower serum cholesterol and triglycerides. MB07811, a small molecule that is administered orally, has been extensively studied preclinically and is currently undergoing clinical testing. MB07811 combines a novel thyroid hormone receptor agonist with the...
Investigational
Matched Description: … MB07811 is the first of a novel class of product candidates discovered by Metabasis designed to lower ... MB07811, a small molecule that is administered orally, has been extensively studied preclinically and ... MB07811 combines a novel thyroid hormone receptor agonist with the Company's novel HepDirect liver targeting …
Tesofensine
Investigational
Narnatumab
Narnatumab is under investigation in clinical trial NCT01119456 (A Study of IMC-RON8 in Advanced Solid Tumors).
Investigational
Matched Description: … Narnatumab is under investigation in clinical trial NCT01119456 (A Study of IMC-RON8 in Advanced Solid …
TW-37
TW-37 is a small-molecule inhibitor of Bcl-2 investigated for its anti-cancer properties.
Investigational
Matched Description: … TW-37 is a small-molecule inhibitor of Bcl-2 investigated for its anti-cancer properties.[A253157] …
CGX-1321
CGX-1321 is a porcupine inhibitor that affects Wnt production and can block Wnt downstream signaling.
Investigational
Matched Description: … CGX-1321 is a porcupine inhibitor that affects Wnt production and can block Wnt downstream signaling. …
MEDI-491
MEDI-491 is a recombinant human parvovirus B19 vaccine composed of the VP1 and VP2 capsid proteins.
Investigational
Matched Description: … MEDI-491 is a recombinant human parvovirus B19 vaccine composed of the VP1 and VP2 capsid proteins. …
BHT-3034
BHT-3034 is a DNA plasmid vaccine immunotherapy under investigation for the treatment of myasthenia gravis.
Investigational
Matched Description: … BHT-3034 is a DNA plasmid vaccine immunotherapy under investigation for the treatment of myasthenia gravis …
RAG-17
RAG-17 is a siRNA oligonucleotide designed to target and knockdown the expression of superoxide dismutase (SOD).
Investigational
Matched Description: … RAG-17 is a siRNA oligonucleotide designed to target and knockdown the expression of superoxide dismutase …
CEB-01
CEB-01 is a biocompatible polymeric PLGA nanofiber membrane containing the active substance 7-ethyl-10-hydroxycamptothecin
Investigational
Matched Description: … CEB-01 is a biocompatible polymeric PLGA nanofiber membrane containing the active substance 7-ethyl-10 …
Sulfatide
Any of a class of cerebroside sulfuric esters, they are found largely in the medullated nerve fibers and may accumulate in metachromatic leukodystrophy.
Experimental
Matched Description: … Any of a class of cerebroside sulfuric esters, they are found largely in the medullated nerve fibers …
Lemuteporfin
Lemuteporfin, under development by QLT Incorporated, is a benzoporphyrin-derived chlorin-like photosensitizer. It is intended for the treatment of beign prostatic hyperplasia.
Investigational
Matched Description: … Lemuteporfin, under development by QLT Incorporated, is a benzoporphyrin-derived chlorin-like photosensitizer …
Fontolizumab
Fontolizumab (marketed under the trade name HuZAF™) is a humanized monoclonal antibody which is used as an immunosuppressive drug to treat Crohn's disease.
Investigational
Matched Description: … Fontolizumab (marketed under the trade name HuZAF™) is a humanized monoclonal antibody which is used …
TP-508
TP508 is a non-proteolytic synthetic peptide representing the portion of human thrombin originally identified as the fibroblast high-affinity receptor binding domain.
Investigational
Matched Description: … TP508 is a non-proteolytic synthetic peptide representing the portion of human thrombin originally identified …
Hydracarbazine
Hydracarbazine is a pyridazine that has found use as an antihypertensive agent It was once marketed in France under the tradename Normatensyl.
Experimental
Matched Description: … Hydracarbazine is a pyridazine that has found use as an antihypertensive agent [A19790] It was once marketed …
Robenacoxib
Robenacoxib is a non-steroidal anti-inflammatory drug used in veterinary medicine for the relief of pain and inflammation in cats and dogs.
Experimental
Vet approved
Matched Description: … Robenacoxib is a non-steroidal anti-inflammatory drug used in veterinary medicine for the relief of pain …
Imidocarb
Imidocarb is a urea derivative used in veterinary medicine as an antiprotozoal agent for the treatment of infection with Babesia and other parasites.
Vet approved
Matched Description: … Imidocarb is a urea derivative used in veterinary medicine as an antiprotozoal agent for the treatment …
Magnolia kobus flowering top
Magnolia kobus flowering top is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Description: … Magnolia kobus flowering top is a plant/plant extract used in some OTC (over-the-counter) products. …
Chamaecyparis obtusa wood oil
Chamaecyparis obtusa wood oil is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Description: … Chamaecyparis obtusa wood oil is a plant/plant extract used in some OTC (over-the-counter) products. …
Chlorotoxin
Chlorotoxin is under investigation in clinical trial NCT00733798 (A Safety and Efficacy Study of Intravenous 131I-TM601 in Adult Patients With Malignant Melanoma).
Investigational
Matched Description: … Chlorotoxin is under investigation in clinical trial NCT00733798 (A Safety and Efficacy Study of Intravenous …
REC-994
REC-994 was cleared by the FDA in July, 2018 for a phase I trial for the treatment of cerebral cavernous malformation (CCM).
Investigational
Matched Description: … REC-994 was cleared by the FDA in July, 2018 for a phase I trial for the treatment of cerebral cavernous …
Levophencynonate
Levophencynonate is under investigation in clinical trial NCT02299804 (A Clinical Trial to Evaluate Efficacy and Safety of Levophencynonate Hydrochloride in Patient With Vertigo).
Investigational
Matched Description: … Levophencynonate is under investigation in clinical trial NCT02299804 (A Clinical Trial to Evaluate Efficacy …
Displaying drugs 11401 - 11425 of 12129 in total