Displaying drugs 1126 - 1150 of 1465 in total
alpha-Fluoro-carboxymethyldethia coenzyme A complex
Experimental
Matched Name: … alpha-Fluoro-carboxymethyldethia coenzyme A complex …
Alpha-Methyl-N-Acetyl-D-Glucosamine
Experimental
Matched Name: … Alpha-Methyl-N-Acetyl-D-Glucosamine …
Avalglucosidase alfa
Avalglucosidase alfa, or NeoGAA, is a drug for enzyme replacement therapy specifically designed for Pompe disease, a rare inherited neuromuscular disorder caused by the deficiency of the alpha-glucosidase (GAA) enzyme. GAA is an essential enzyme that hydrolyzes glycogen into free glucose for use in cellular functions. In Pompe disease, the...
Approved
Investigational
Matched Synonyms: … Neo-recombinant human acid alpha-glucosidase …
Matched Description: … , especially in smooth, cardiac, and skeletal muscle cells. ... In Pompe disease, the GAA enzyme is missing and patients are unable to properly break down glycogen, ... resulting in the accumulation of glycogen within lysosomes and progressive disruption of cellular function …
Matched Categories: … Alimentary Tract and Metabolism ... Enzymes and Coenzymes …
Matched Description: … , especially in smooth, cardiac, and skeletal muscle cells. ... In Pompe disease, the GAA enzyme is missing and patients are unable to properly break down glycogen, ... resulting in the accumulation of glycogen within lysosomes and progressive disruption of cellular function …
Matched Categories: … Alimentary Tract and Metabolism ... Enzymes and Coenzymes …
ASTX-029
ASTX-029 is under investigation in clinical trial NCT03520075 (Study of ASTX029 in Subjects With Advanced Solid Tumors).
Investigational
Matched Synonyms: … -METHYL-1-OXO-, (.ALPHA.R)- ... 2H-PYRAN-4-YL)AMINO)-4-PYRIMIDINYL)-N-((1S)-1-(3-FLUORO-5-METHOXYPHENYL)-2-HYDROXYETHYL)-1,3-DIHYDRO-.ALPHA …
Adenosine-5'-Rp-Alpha-Thio-Triphosphate
Experimental
Matched Name: … Adenosine-5'-Rp-Alpha-Thio-Triphosphate …
3-(alpha-D-Galactopyranosyloxy)-5-nitrobenzamide
Experimental
Matched Synonyms: … 5-aminocarbonyl-3-nitrophenyl-alpha-D-galactopyranose …
Matched Name: … 3-(alpha-D-Galactopyranosyloxy)-5-nitrobenzamide …
Matched Name: … 3-(alpha-D-Galactopyranosyloxy)-5-nitrobenzamide …
Glucosaminyl-(Alpha-6)-D-Myo-Inositol
Experimental
Matched Name: … Glucosaminyl-(Alpha-6)-D-Myo-Inositol …
2-O-methyl-alpha-L-fucopyranose
Experimental
Matched Synonyms: … 6-deoxy-2-O-methyl-alpha-L-galactopyranose …
Matched Name: … 2-O-methyl-alpha-L-fucopyranose …
Matched Name: … 2-O-methyl-alpha-L-fucopyranose …
Ciliary neurotrophic factor
NT-501 is an intraocular implant that contains human cells that have been genetically modified to secrete ciliary neurotrophic factor (CNTF). It is under investigation for the treatment of retinitis pigmentosa and age-related macular degeneration.
Investigational
Matched Synonyms: … allogenic retinal epithelial cells transfected with plasmid vector expressing ciliary neurotrophic growth …
Matched Description: … [L46762] It is under investigation for the treatment of retinitis pigmentosa and age-related macular …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins ... Nerve Tissue Proteins …
Matched Description: … [L46762] It is under investigation for the treatment of retinitis pigmentosa and age-related macular …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins ... Nerve Tissue Proteins …
Alphameprodine
Alphameprodine is an opioid analgesic classified by the United States Drug Enforcement Administration under Schedule I of illegal substances. The stereoisomer betameprodine is similarly classified, however alphameprodine is more widely used (both are referred to as Meprodine). Alphameprodine is a structural analogue of meperidine. It exerts physiological effects characteristic of...
Experimental
Illicit
Matched Synonyms: … alpha-3-ethyl-1-methyl-4-phenyl-4-propionoxypiperidine ... alpha-3-Ethyl-1-methyl-4-phenyl-4-propionyloxypiperidine …
Matched Description: … as well as itching, nausea, and respiratory depression. ... It exerts physiological effects characteristic of opioids, such as analgesia, euphoria and sedation, …
Matched Description: … as well as itching, nausea, and respiratory depression. ... It exerts physiological effects characteristic of opioids, such as analgesia, euphoria and sedation, …
Ephedrine
Ephedrine was first described in western literature in 1888, as a naturally occurring component of the ephedra plant, along with pseudoephedrine. Ephedrine acts as both a direct and indirect sympathomimetic. It is an alpha- and beta-adrenergic receptor agonist; however, it also causes the indirect release of norepinephrine from sympathetic neurons,...
Approved
Matched Description: … It is an alpha- and beta-adrenergic receptor agonist; however, it also causes the indirect release of ... [A193698] Ephedrine acts as both a direct and indirect sympathomimetic. ... norepinephrine from sympathetic neurons, inhibiting norepinephrine reuptake and displacing more norepinephrine …
Matched Categories: … Alpha-and Beta-adrenergic Agonists ... Adrenergic alpha-Agonists ... Adrenergic and Dopaminergic Agents ... Alimentary Tract and Metabolism ... Epinephrine and similars …
Matched Products: … HanPoong Gal Cheon Xin Extract Granules …
Matched Categories: … Alpha-and Beta-adrenergic Agonists ... Adrenergic alpha-Agonists ... Adrenergic and Dopaminergic Agents ... Alimentary Tract and Metabolism ... Epinephrine and similars …
Matched Products: … HanPoong Gal Cheon Xin Extract Granules …
N-{[(2S,3S)-3-(ETHOXYCARBONYL)OXIRAN-2-YL]CARBONYL}-L-ISOLEUCYL-L-ISOLEUCINE
Experimental
Matched Name: … N-{[(2S,3S)-3-(ETHOXYCARBONYL)OXIRAN-2-YL]CARBONYL}-L-ISOLEUCYL-L-ISOLEUCINE …
Ritodrine
Adrenergic beta-agonist used to control premature labor.
Approved
Investigational
Matched Synonyms: … p-Hydroxy-alpha-(1-((p-hydroxyphenethyl)amino)ethyl)benzyl alcohol …
Matched Categories: … Genito Urinary System and Sex Hormones …
Matched Categories: … Genito Urinary System and Sex Hormones …
Tolterodine
Tolterodine is an antimuscarinic drug that is used to treat urinary incontinence. Tolterodine acts on M2 and M3 subtypes of muscarinic receptors.
Approved
Investigational
Matched Synonyms: … (+)-(R)-2-(alpha-(2-(Diisopropylamino)ethyl)benzyl)-p-cresol …
Matched Description: … Tolterodine acts on M2 and M3 subtypes of muscarinic receptors. …
Matched Categories: … Genito Urinary System and Sex Hormones ... Drugs for Urinary Frequency and Incontinence …
Matched Description: … Tolterodine acts on M2 and M3 subtypes of muscarinic receptors. …
Matched Categories: … Genito Urinary System and Sex Hormones ... Drugs for Urinary Frequency and Incontinence …
5-O-phosphono-alpha-D-ribofuranosyl diphosphate
The key substance in the biosynthesis of histidine, tryptophan, and purine and pyrimidine nucleotides.
Approved
Experimental
Investigational
Matched Synonyms: … 5-Phospho-alpha-D-ribose 1-diphosphate …
Matched Name: … 5-O-phosphono-alpha-D-ribofuranosyl diphosphate …
Matched Description: … The key substance in the biosynthesis of histidine, tryptophan, and purine and pyrimidine nucleotides …
Matched Name: … 5-O-phosphono-alpha-D-ribofuranosyl diphosphate …
Matched Description: … The key substance in the biosynthesis of histidine, tryptophan, and purine and pyrimidine nucleotides …
Maltosyl-Alpha (1,4)-D-Gluconhydroximo-1,5-Lactam
Experimental
Matched Name: … Maltosyl-Alpha (1,4)-D-Gluconhydroximo-1,5-Lactam …
2,3-Di-O-Sulfo-Alpha-D-Glucopyranose
Experimental
Matched Name: … 2,3-Di-O-Sulfo-Alpha-D-Glucopyranose …
N7-(5'-Phospho-alpha-ribosyl)-2-hydroxypurine
Experimental
Matched Name: … N7-(5'-Phospho-alpha-ribosyl)-2-hydroxypurine …
4,6-dideoxy-4-amino-alpha-D-glucose
Experimental
Matched Name: … 4,6-dideoxy-4-amino-alpha-D-glucose …
N-Benzyl-3-(alpha-D-galactopyranosyloxy)benzamide
Experimental
Matched Name: … N-Benzyl-3-(alpha-D-galactopyranosyloxy)benzamide …
Prenylamine
Prenylamine was withdrawn from the Canadian, US, and UK markets in 1988 due to concerns regarding cardiac arrhythmias.
Approved
Withdrawn
Matched Synonyms: … N-(3,3-Diphenylpropyl)-alpha-methylphenaethylamin ... N-(3,3-Diphenylpropyl)-alpha-methylphenethylamine …
Matched Description: … Prenylamine was withdrawn from the Canadian, US, and UK markets in 1988 due to concerns regarding cardiac …
Matched Categories: … Calcium-Regulating Hormones and Agents …
Matched Description: … Prenylamine was withdrawn from the Canadian, US, and UK markets in 1988 due to concerns regarding cardiac …
Matched Categories: … Calcium-Regulating Hormones and Agents …
Brimonidine
Brimonidine is an alpha-adrenergic agonist and 2-imidazoline derivative that was first introduced in 1996. It is considered to be a third generation alpha-2 aadrenergic receptor agonist, since it displays preferential binding at alpha-2 adrenoceptors over alpha-1 receptors. Brimonidine displays a higher selectivity toward the alpha-2 adrenergic receptors than clonidine or...
Approved
Matched Description: … Brimonidine is an alpha-adrenergic agonist and 2-imidazoline derivative that was first introduced in ... Early treatment and management of glaucoma, which predominantly involves the lowering of intraocular ... Ophthalmically, brimonidine is used to lower intraocular pressure by reducing aqueous humor production and …
Matched Mixtures name: … Brimonidine Tartrate and Timolol Maleate ... BRIMONIDINE TARTRATE and TIMOLOL MALEATE ... Brimonidine Tartrate and Timolol Maleate …
Matched Categories: … Skin and Mucous Membrane Agents ... Antiglaucoma Preparations and Miotics ... Decongestants and Antiallergics ... Adrenergic alpha-Agonists ... Adrenergic alpha-2 Receptor Agonists …
Matched Products: … Alpha-Vision sine 2 mg/ml Augentropfen, Lösung im Einzeldosisbehältnis …
Matched Mixtures name: … Brimonidine Tartrate and Timolol Maleate ... BRIMONIDINE TARTRATE and TIMOLOL MALEATE ... Brimonidine Tartrate and Timolol Maleate …
Matched Categories: … Skin and Mucous Membrane Agents ... Antiglaucoma Preparations and Miotics ... Decongestants and Antiallergics ... Adrenergic alpha-Agonists ... Adrenergic alpha-2 Receptor Agonists …
Matched Products: … Alpha-Vision sine 2 mg/ml Augentropfen, Lösung im Einzeldosisbehältnis …
Buclizine
Buclizine is an antihistamine medication with both antiemetic and anticholinergic effects , belonging to the piperazine derivative family of drugs. It was manufactured by Stuart Pharms and initially approved by the FDA in 1957. Following this, it was touted to be effective as an appetite stimulant in children when administered...
Approved
Matched Synonyms: … 1-(p-tert-Butylbenzyl)-4-(4-chloro-alpha-phenylbenzyl)piperazine …
Matched Description: … Buclizine is an antihistamine medication with both antiemetic and anticholinergic effects [L6220], belonging ... It was manufactured by Stuart Pharms and initially approved by the FDA in 1957. ... in the treatment of nausea and vomiting during pregnancy. …
Matched Description: … Buclizine is an antihistamine medication with both antiemetic and anticholinergic effects [L6220], belonging ... It was manufactured by Stuart Pharms and initially approved by the FDA in 1957. ... in the treatment of nausea and vomiting during pregnancy. …
Displaying drugs 1126 - 1150 of 1465 in total